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The information may be unavailable due to the results not being approved or confirmed. In particular, when a call includes regions where projects are cofunded by EC funds and others where that is not the case, confirmation or approval may be not simultaneous.
New neurohumoral pathways in Pulmonary Arterial Hypertension - Pathophysiologic and therapeutic implications. Joaquim Adelino Correia Ferreira Leite Moreira, Faculdade de Medicina da Universidade do Porto (FM/UP). €75,000.
Neuroprotective role of insulin and IGF-1 against Huntington´s disease-associated diabetes. Ana Cristina Carvalho Rego, Centro de Neurociências e Biologia Celular (CNBC/UC). €124,000.
alpha2C adrenoceptors in the adrenal medulla and cardiovascular profile. Maria Augusta Vieira Coelho, Faculdade de Medicina da Universidade do Porto (FM/UP). €85,000.
Microglial and Neuronal Changes in the Hippocampus Induced by Methamphetamine: Role of Pro-inflammatory Cytokines and Neuropeptide Y. Ana Paula Pereira da Silva Martins, Associação para a Investigação Biomédica e Inovação em Luz e Imagem (AIBILI). €88,000.
ROLE OF DENDRITIC CELLS IN LEISHMANIASIS: intracellular signalling pathways activated by virulent and attenuated parasite Leismania infantum. Anabela Cordeiro-da-Silva, Instituto de Biologia Molecular e Celular (IBMC/UP). €80,000.
Susceptibility of non-subtype B HIV-1 and HIV-2 isolates to entry inhibitors: identification and characterization of new pathways of resistance. Nuno Eduardo Moura dos Santos da Costa Taveira, Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM). €100,000.
Study of the effect of non-steroidal anti-inflammatory drugs on membrane enzymes and receptors with a relevant role in inflammatory processes and cellular pro-inflammatory signalization. Maria de La Salette de Freitas Fernandes Hipólito Reis, Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA). €92,850.
Interplay between adenosine and angiotensin II and glomerular injury in Diabetes with associated Hypertension: a putative new therapeutic target? Manuela Morato, Faculdade de Medicina da Universidade do Porto (FM/UP). €105,000.
Intestinal transport of diet components and protection against colorectal cancer. Fátima Martel, Faculdade de Medicina da Universidade do Porto (FM/UP). €62,360.
Neurodegeneration in a Transgenic Animal Model of Alzheimer`s Disease: Role of Apoptosis and its Modulation. Cecília Maria Pereira Rodrigues, Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa). €120,000.
Membrane receptors and mediators involved in plastic changes induced by neuronal insults: implications for neuroprotection. Joaquim Alexandre Ribeiro, Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa). €160,000.
Study of the blood-brain barrier disruption by neurotoxins and modulation by therapeutic agents in a human model: effects of bilirubin and endotoxin on brain microvascular endothelial cell monolayer integrity and protective role of bile acids. Maria Alexandra de Oliveira Silva Braga Pedreira de Brito, Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa). €120,000.
Quantitative Modeling of Passive Trancytotic Diffusion of Amphiphilic Molecules Across the Blood-Brain Barrier. Maria João Pedrosa Ferreira Moreno Silvestre, Universidade de Coimbra (UC). €167,000.
Targeting effective kyotorphin derivatives to the brain. Miguel Castanho, Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa). €126,000.
Silencing Machado-Joseph disease: lentiviral-mediated RNA interference to ataxin-3. LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA, Centro de Neurociências e Biologia Celular (CNBC/UC). €170,000.
IN VIVO/IN VITRO CORRELATION OF INTESTINAL ABSORPTION OF PROTEINS USING ANIMAL MODELS AND CACO-2 BASED CO-CULTURE CELL LINES. Domingos de Carvalho Ferreira, Faculdade de Farmácia da Universidade do Porto (FF/UP). €138,000.
Preparation of therapeutic ophthalmic articles using molecular imprinting methods and supercritical fluids. Hermínio José Cipriano de Sousa, PRODEQ - Associação para o Desenvolvimento da Engenharia Química (PRODEQ). €141,000.
Bone Turnover Associated-Pharmacogenomic Profile of Patients with Metastatic and Non-Metastatic Prostate Cancer: Predictive Factors for the Benefits of Bisphosphonate Treatment? RUI Manuel de MEDEIROS Melo Silva MEDEIROS, Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto). €143,000.
IMATINIB RESISTANCE AND TARGETS IN CHRONIC MYELOID LEUKAEMIA: POST-GENOMIC APPROACHES USING YEAST AS MODEL SYSTEM. Isabel Maria de Sá Correia Leite de Almeida, Instituto Superior Técnico (IST/ULisboa). €150,000.
Mechanisms of neuronal plasticity and neuroprotection induced by BDNF in the hippocampus: inhibition of degeneration vs. regeneration. Carlos Jorge Alves Miranda Bandeira Duarte, Centro de Neurociências e Biologia Celular (CNBC/UC). €136,000.
Characterization of lytic genes encoded by mycobacteriophages with antimicrobial activity against mycobacteria. Madalena Maria Vilela Pimentel, Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM). €80,000.
Regulation of intracellular anti-viral defense factor APOBEC3G as therapeutic strategy to control HIV-1 infection. Inês Sampaio de Sousa Soeiro, Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM). €122,820.
Role of extracellular ATP and characterization of purinergic receptors in the resistance of Candida albicans to macrophage attack. Teresa Maria Fonseca de Oliveira Gonçalves, Centro de Neurociências e Biologia Celular (CNBC/UC). €78,936.