This website was discontinued on 20/12/2022. Visit the new website at www.fct.pt.
The information may be unavailable due to the results not being approved or confirmed. In particular, when a call includes regions where projects are cofunded by EC funds and others where that is not the case, confirmation or approval may be not simultaneous.
Looking for evidences of human adaptation in the proteolysis universe: the case-study of serine protease inhibitors. Susana Seixas, Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP). €178,700.
Therapeutic approaches for Machado-Joseph disease: study in a mouse model. Patrícia Espinheira de Sá Maciel, Universidade do Minho (UM). €159,934.
Estrogen signaling and epigenetic modifications in the regulation of the CYP46A1 expression in the brain. Elsa Margarida Teixeira Rodrigues, Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa). €124,630.
Genetic epidemiology of stroke in the post-genomic era. Ana Sofia Simões Domingues de Almeida Oliveira, Fundação Calouste Gulbenkian (FCG). €194,000.
microRnomics and proteomics of Parkinson's disease. Ana Sofia Simões Domingues de Almeida Oliveira, Fundação Calouste Gulbenkian (FCG). €121,960.
Study of post-transcriptional regulation of HFE gene expression - a contribution to understand its role in iron homeostasis and in Hereditary Hemochromatosis development. Maria Paula Duarte Faustino Gonçalves, Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ). €149,790.
Molecular Genetics and Functional Genomics of Autism Spectrum Disorders. Astrid Vicente, Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ). €199,940.
The polyglycine expansion in the N-terminal domain of eRF3a in cancer development. Miguel Brito, Instituto Politécnico de Lisboa (IPL). €179,079.
THE GENETICS OF CD8+ T LYMPHOCYTE HOMEOSTASIS: implications in the clinical expression of Hereditary Hemochromatosis. Maria da Graça Beça Gonçalves Porto, Instituto de Biologia Molecular e Celular (IBMC/UP). €156,382.
Unravelling the in vitro epigenetic effects of intracellular S-adenosylhomocysteine accumulation on nitric oxide bioavailability. Maria Rita M A Azevedo e Castro, Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa). €74,850.
Mechanisms of splicing regulation by U2AF proteins. Maria Carmo-Fonseca, Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa). €194,445.
Functional analysis and origins of the pathophysiology of mutations within genes of the fatty acid oxidation pathway: implications in the multiple acyl-CoA dehydrogenase deficiency disorder. Cláudio Emanuel Moreira Gomes, ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL). €70,801.
Genome-wide screening with libraries of synthetic zinc-finger proteins capable to modulate host gene expression: Application in HIV-1 infection. Joao Goncalves, Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM). €168,100.
Mechanisms of Resistance to Imatinib in Chronic Myeloid Leukemia. Maria Purificação Valenzuela Sampaio Tavares, Centro de Genética Clínica e Patologia Prof. Amândio S. Tavares, Lda. (CGC). €125,000.
The study of Antley-Bixler Syndrome related mutations of cytochrome P450 oxidoreductase: CYPOR polymorphism and the human cytochrome P450 enzyme complex. Michel Kranendonk, Faculdade de Ciências Médicas (FCM/UNL). €151,874.
Papel de novos mechanismos regulatórios na perda de expressão da caderina-E. Carla Oliveira, Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP). €150,000.
Determine if the loss of heterozygosity for JAK2 V617F mutation along with the circulating levels of CD34+ and activated granulocytes and platelets are associated with disease progression in Myeloproliferative disorders patients. Maria Letícia de Sousa Ribeiro, Centro Hospitalar de Coimbra E.P.E. (CHC). €199,950.