This website was discontinued on 20/12/2022. Visit the new website at www.fct.pt.

Skip nav

R&D Projects

Proposals for Research Projects in all Scientific Domains - 2006

Painel de Avaliação de Neurociências - 2006

Coordination

Therese Jay
Université Paris Descartes, France

Evaluation

Denis Hervé
Institut du Fer à Moulin, France
Laurent Journot
Institut de Genomique Fonctionelle - Universités Montpellier I & II, France
Michael Corner
Netherlands Institute for Neuroscience, Netherlands
Roland Pochet
Faculté de Medicine, Belgium
Therese Jay
Université Paris Descartes, France

Projects assigned

PTDC/SAU-NEU/64066/2006

Brain inflammatory response and progressive neurodegeneration: study in Machado-Joseph disease and Huntington disease mouse models
Patrícia Espinheira de Sá Maciel
Universidade do Minho (UM)

PTDC/SAU-NEU/64096/2006

Role of neurotrophic factors in the pathogenesis of Machado-Joseph disease: study in a mouse model
Patrícia Espinheira de Sá Maciel
Universidade do Minho (UM)

PTDC/SAU-NEU/64098/2006

Chromatin remodelling and plasticity of the nervous system: study of the synapse structure and proteome in a mouse model of Rett syndrome
Patrícia Espinheira de Sá Maciel
Universidade do Minho (UM)

PTDC/SAU-NEU/64126/2006

Trophic actions of neurotrophic factors: dependency of adenosine A2A receptors co-activation
Ana Maria Ferreira Sousa Sebastião
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/64151/2006

Design, synthesis and biological assessment of multifunctional compounds as anti-Alzheimer drugs
Maria Carmo Damaso Costa Silva A Carreiras
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NEU/64327/2006

Carbon monoxide as a neuroprotective agent against hypoxia-ischemia and reperfusion
Helena Luisa de Araujo Vieira
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-NEU/64345/2006

Impaired pathways in neurodegenerative diseases and treatment approaches
Isabel Alexandra Azevedo Silveira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/64382/2006

Molecular mechanisms of urinary bladder hyperactivity caused by spinal lesions
António Avelino Ferreira Saraiva da Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/64385/2006

Uncovering the potential neurodevelopmental deficits in common neonatal conditions such as hyperbilirubinemia and inflammation
Dora Brites
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NEU/64498/2006

IS THERE A ROLE FOR THE TRANSTHYRETIN-METALLOTHIONEIN INTERACTION IN AMYLOID BETA DEPOSITION?
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/SAU-NEU/64501/2006

Mitochondrial dysfunction towards protein aggregation in Parkinson disease: contribution of cytoskeletal disorganization
Sandra Morais Cardoso
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/64593/2006

Modulation of A-Beta toxicity by transthyretin in AlZheimer´s disease
Isabel dos Santos Cardoso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/64645/2006

Chronic pain control by gene therapy directed to brainstem centres involved in descending pain modulation
Isaura Ferreira Tavares
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/64876/2006

SELF-RENEWAL AND DIFFERENTIATION OF NEURAL STEM CELLS: ANTAGONISTIC ROLES OF APOPTOSIS
SUSANA ZEFERINO SOLÁ DA CRUZ
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NEU/64904/2006

Ageing and Chronic Pain: neuroplasticity of the limbic system and brainstem pain control centres induced by chronic neuropathy with ageing
Armando Almeida
Universidade do Minho (UM)

PTDC/SAU-NEU/64911/2006

Limbic System Contribution for Chronic Pain: which role for the amygdala and hypothalamus in neuropathic pain processing?
Armando Almeida
Universidade do Minho (UM)

PTDC/SAU-NEU/65272/2006

Molecular determinants for NMDA-type glutamate receptor traffic to synapses: implications in synaptic plasticity
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/65568/2006

Role of astrocytes in microglia modulation: involvement in the neuroprotective-neurotoxic microglia switch?
Graça Maria Fernandes Baltazar
Universidade da Beira Interior (UBI)

PTDC/SAU-NEU/65890/2006

Role of presynaptic nicotinic acetylcholine receptors in animal models of Alzheimer´s disease
PAULA MARIA GARCIA AGOSTINHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/65950/2006

Synaptic plasticity in the amygdala: cellular mechanisms of heterosynaptic plasticity in the lateral nucleus of the amygdala.
Rosalina Maria Regada Carvalho Fonseca de Alvarez
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NEU/65990/2006

Cardiovascular variability in pediatric coma: time course and outcome
Ana Paula de Frias Viegas Proença Rocha
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/SAU-NEU/66105/2006

Does the location of epileptic foci influence the growth direction of the brain tumours?
Carla Maria Quintão Pereira
Universidade do Algarve (UAlg)

PTDC/SAU-NEU/66439/2006

Migraine and Cluster Headache: clinical and genetic study
José Maria Pereira Monteiro
Centro de Estudos de Cefaleias (CEC)

PTDC/SAU-NEU/67206/2006

Modulation of neurogenesis by nitric oxide in striatal excitotoxic injury in a model of Huntington's disease
Inês Maria Pombinho de Araújo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/67309/2006

Chronic pain modulation by Locus Coeruleus and Dorsal Raphe Nucleus: mechanism of action of antidepressants in the induction of analgesia
Fani Lourença Moreira Neto
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/67543/2006

Identification of diffusible signals mediating GDNF up-regulation in substantia nigra and striatum upon dopaminergic injury to nigrostriatal dopaminergic neurons.
Graça Maria Fernandes Baltazar
Universidade da Beira Interior (UBI)

PTDC/SAU-NEU/67586/2006

Restoring Function Following Spinal Cord Injury
Artur Varejão
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/SAU-NEU/67769/2006

Cardiovascular regulation and endogenous pain control in hypertension and chronic pain conditions. Role of angiotensin and oxidative stress
Dora Pinho
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/67893/2006

Methamphetamine abuse, seeking for neuroprotection and treatment in a adolescent rat model of exposure
Maria Teresa Burnay Summavielle
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/67913/2006

Pain processing in a human model of injured central nervous system (multiple sclerosis): a functional magnetic resonance imaging study.
Deolinda Maria Valente Alves Lima Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/68170/2006

Neurogenesis as influenced by nitric oxide produced by inflammation in status epilepticus injury
Caetana Angelica Ermitao Monteiro Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/68395/2006

Mesial Temporal Lobe Epilepsy (MTLE): structural and functional abnormalities in brain tissue and their relation with risk factors and pharmaco-resistance
Maria Berta Silva
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-NEU/68411/2006

Cross-talk between alpha-synuclein and amyloid-beta peptides in Alzheimer´s disease
Catarina Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/68619/2006

Molecular basis of neuronal diversity: correlation between gene expression and morphophysiological profile of spinal nociceptive neurons.
Carlos Reguenga
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/69099/2006

Evidences for the involvement of secretory vesicles in local calcium dynamics
Maria Paula Polónia Gonçalves
Universidade de Aveiro (UA)

PTDC/SAU-NEU/69361/2006

Statins: a valuable therapeutic for Alzheimer´s disease?
Cláudia Maria Fragão Pereira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/69531/2006

Risk and reward in prefrontal cortex: neural correlates of decision-making at the single-cell level
Vasco Miguel Clara Lopes Galhardo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/69589/2006

Effects of polyphenols in the Rat brain during chronic ethanol consumption and aging: a behavioural, morphological and biochemical approach.
José Paulo Alves Vieira de Andrade
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/69639/2006

Estrogenic regulation of neuronal activity in dissociated cultures of ventromedial nucleus of the hypothalamus
Maria Dulce Cordeiro Madeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/70120/2006

Neuronal ageing induced by chronic exposure to methamphetamine: from neurobehaviour to proteomics
Maria Amélia Duarte Ferreira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/70290/2006

SEX DIFFERENCES IN THE RESPONSE TO ACUTE STRESS IN LONG-TERM ETHANOL TREATED AND WITHDRAWN RATS
Maria Dulce Cordeiro Madeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/70385/2006

Auto-digesting neurodegeneration in polyglutamine disorders - autophagy as a therapeutic strategy in Machado-Joseph disease
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/70465/2006

Influence of the Cyclically Fluctuating Leves of Sex Steroids in the Structural Organization of the Cerebellar Nuclei
Fernando Pedroso Brandão
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/70504/2006

Pontomesencephalic cholinergic projections to the forebrain: implications in stress response and cognitive processes.
NIKOLAY VSEVOLODOVICH LUKOYANOV
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/70854/2006

In vivo Nitric Oxide Dynamics in the brain. Relevance for brain aging and neurodegenerative disorders
João António Nave Laranjinha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/71033/2006

Evaluation by Functional Magnetic Resonance Imaging (fMRI) of the effects Physical Activity´s in the Brain of the Multiple Sclerosis deasease
Manuel Ferreira da Conceição Botelho
Faculdade de Desporto da Universidade do Porto (FADE/UP)

PTDC/SAU-NEU/71070/2006

Effects of nutritional deprivations in the hippocampal formation of the adult Rat. Interaction with chronic ethanol consumption.
José Paulo Alves Vieira de Andrade
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/71135/2006

Analisys of the Drawing Style and Eye Tracking in People with Asperger Syndrome
Carlos Manuel Nunes Filipe
CADIn - Centro de Apoio ao Desenvolvimento Infantil (CADIn)

PTDC/SAU-NEU/71310/2006

Stem cell based therapy for inner ear hair cell regeneration
Domingos Manuel Pinto Henrique
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/71442/2006

Determination of the Early Abnormalities in Familial Amyloid Polyneuropathy
Mamede de Carvalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/71647/2006

How do we learn the association of events separate in time? A Study on the mechanisms underlying auditory trace fear conditioning.
Marta de Aragão Pacheco Moita
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NEU/72048/2006

Insulin and Alzheimeir's disease: alterations in neuroexciability- shared and specific cellular mechanisms.
Pedro Afonso dos Santos Baltazer de Lima
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-NEU/72050/2006

Subthalamic Nucleus Deep Brain Stimulation cognitive effect in Parkinson's Disease patients: EEG/ERP and SPECT study
Maria Carolina Lobo de Almeida Garrett
Hospital de São João EPE (HSJ)

PTDC/SAU-NEU/72331/2006

Identification of biomarkers for Multiple Sclerosis in the cerebrospinal fluid and serum
Catarina Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/72836/2006

Molecular mechanisms coupling calcium-permeable AMPA receptors to excitotoxic signalling pathways
Armanda Emanuela Castro e Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/72879/2006

Are genetic variants in genes regulating exocytosis and cell signalling guilty of compulsive alcohol consumption?
Alda Maria Abreu Cardoso
Instituto Nacional de Medicina Legal e Ciências Forense, I.P. (INMLCF/MJ)

PTDC/SAU-NEU/72995/2006

Phosphorylation Dependent Neuronal Targeting of the Alzheimer´s Amyloid Precursor Protein
Odete A B da Cruz e Silva
Universidade de Aveiro (UA)

PTDC/SAU-NEU/73108/2006

Cognitive Performance in Adults with Attention Deficit / Hyperactivity Disorder and their First-Degree Relatives: Contribution to the Study of Endophenotypes.
Carlos Manuel Nunes Filipe
CADIn - Centro de Apoio ao Desenvolvimento Infantil (CADIn)

PTDC/SAU-NEU/73209/2006

Mechanisms of regulation of the proteasome under excitotoxic conditions
Paulo Pereira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/73257/2006

Impact of hyperglycemia on exocytosis in neuronal tissues
António Francisco Rosa Gomes Ambrósio
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-NEU/73662/2006

NEUROTOXICITY OF AMPHETAMINE DERIVATIVES. ROLE OF METABOLISM AND CELLULAR SIGNALLING SYSTEMS
Félix Carvalho
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-NEU/74035/2006

Myelomeningocele: characterization of the mechanisms of lesion and surgical repair in mutant mice models of spina bifida
Joaquim Luís Ramos Torres Couto Reis
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-NEU/74154/2006

TARGETING THE ENDOCANNABINOID SYSTEM AGAINST TYPE 2 DIABETES-INDUCED ENCEPHALOPATHY
Attila Köfalvi
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/74318/2006

EFFECT OF PURINES IN THE DEVELOPING HIPPOCAMPUS: CONSEQUENCES FOR THE ESTABLISHMENT OF CIRCUITS RELATED TO LEARNING AND MEMORY
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/74463/2006

Measurement of Neuropeptides in Neurosciences and Clinical Medicine
João Maria Martin Martins
Faculdade de Medicina da Universidade de Lisboa (FM/ULisboa)

PTDC/SAU-NEU/81184/2006

Perfusion of the brain and cardiac dysfunction in patients with coronary heart disease
Isabel Maria Amorim Pereira Ramos
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/65548/2006

Sensory processing in synapses of excitatory interneurons from the spinal substantia gelatinosa
Boris Safronov
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/65846/2006

Cleavage of the vesicular glutamate (VGLUT) and GABA (VGAT) transporters under excitotoxic conditions: identification of the cleavage sites and functional implications
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/66740/2006

Animal model of Fabry disease: can the neuropathophysiology events be correlated with lipidomics?
Maria Clara Pereira de Sá Miranda
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/68141/2006

Seizure-induced reorganization of synaptic connections in the limbic system and its functional implications
NIKOLAY VSEVOLODOVICH LUKOYANOV
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/68465/2006

Subventricular zone stem cells as a tool for brain repair in temporal lobe epilepsy
Joao Jose Oliveira Malva
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/68470/2006

Identification of the mechanisms allowing central nervous system regeneration after a pre-conditioning injury to the peripheral nervous system.
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/68483/2006

Retinocortical visual processing in normal and pathological aging and neurodevelopment
Miguel de Sá e Sousa de Castelo Branco
Associação para a Investigação Biomédica e Inovação em Luz e Imagem (AIBILI)

PTDC/SAU-NEU/68929/2006

Theoretical models of nociceptive information processing and transmission in the spinal cord´s dorsal horn.
Paulo de Castro Aguiar
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/69123/2006

Plant TTL and human RAGE: any common features between the signaling pathways in plant development and human nerve degeneration?
Ana Margarida Moreira Leitão de Barros Martins Damas
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/69831/2006

Role of transforming growth factor beta in the myelination and remyelination of the central nervous system
Joao Carlos Bettencourt de Medeiros relvas
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/70161/2006

UNCOVERING PATHOLOGICAL MECHANISM UNDERLYING JUVENILE NEURONAL CEROID LIPOFUSCINOSES: FROM YEAST TO MORE COMPLEX MODEL SYSTEMS
Fernando José dos Santos Rodrigues
Universidade do Minho (UM)

PTDC/SAU-NEU/71228/2006

Regulation of AMPA receptors by hyperglycemia in the retina
António Francisco Rosa Gomes Ambrósio
Universidade de Coimbra (UC)

PTDC/SAU-NEU/71675/2006

Contribution of N-methyl-D-aspartate receptor subunits to neuronal dysfunction in Alzheimer's disease
Ana Cristina Carvalho Rego
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/72699/2006

New perspectives in the neurobiology of depression: beyond the “neurochemical hypothesis”
Nuno Jorge Carvalho de Sousa
Universidade do Minho (UM)

PTDC/SAU-NEU/73119/2006

Neuropeptide Y in the retina: Why? What for?
CLÁUDIA MARGARIDA GONÇALVES CAVADAS
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/81064/2006

Interaction between nicotine and caffeine in the striatum. Relevance for Parkinson´s disease
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/81153/2006

Molecular Determinants of Brain Size.
Maria do Carmo Pinto Basto Avides Moreira
Universidade do Minho (UM)