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R&D Projects

Call for Projects on Clinical and Translational Research Grants - Cooperation Agreement between Portugal and Harvard Medical School - 2013

Painel da Avaliação - 2013 - Concurso de Projetos de IC&DT no âmbito do Acordo de Cooperação entre Portugal e a Harvard Medical School - 2013 / Investigação Clínica e de Translação

Coordination

David S Pellman

Evaluation

David S Pellman
Harvard Medical School, United States
José Eduardo Torres de Eckenroth Guimaraes
Faculdade de Medicina do Porto, Portugal
Stephen Copan Harrison
Harvard Medical School, United States

Projects assigned

HMSP-ICT/0003/2013

Application of a synergist therapy in experimental Cerebral Ischemia
Sofia Santos
Instituto de Biologia Molecular e Celular (IBMC/UP)

HMSP-ICT/0004/2013

Insulin therapy of chronic wounds in diabetes - its role on skin insulin action, immune activation and microbiota
EUGÉNIA MARIA LOURENÇO DE CARVALHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

HMSP-ICT/0005/2013

Heme metabolism and the microbiome in liver regeneration
Carlos José Rodrigues Crispim Romão
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

HMSP-ICT/0006/2013

Pre-clinical development of NF-kB inhibitor dimethylaminoparthenolide (DMAPT) for treating genitourinary cancers.
Rui Miguel Gil da Costa
Faculdade de Engenharia da Universidade do Porto (FE/UP)

HMSP-ICT/0007/2013

Hippocampus Malplasticity in Chronic Pain Syndromes
Vasco Miguel Clara Lopes Galhardo
Faculdade de Medicina da Universidade do Porto (FM/UP)

HMSP-ICT/0009/2013

Adenosine A2A receptors and alpha-synuclein: basis for early cognitive deficits in Parkinson's Disease
Luisa Vaqueiro Lopes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0010/2013

Role of Scavenger Receptors in Human Listeriosis: Towards Innovative Therapeutic Strategies.
Didier Cabanes
Instituto de Biologia Molecular e Celular (IBMC/UP)

HMSP-ICT/0012/2013

Molecular Imaging of Liver Fibrosis
Gonçalo Bernardes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0013/2013

Evaluation of carbon monoxide releasing molecules as candidates for the treatment of rheumatoid arthritis
João Eurico Cortez Cabral da Fonseca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0015/2013

Changing dietary habits in Africa: the impact of host diet on the malaria transmission cycle
Miguel Prudêncio
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0016/2013

Next-Gen Cytogenetics Enters Clinical Care and Annotates the Human Genome
Dezso David
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

HMSP-ICT/0019/2013

Protective function of apolipoprotein against diabesity-linked liver disease
John Griffith Jones
Centro de Neurociências e Biologia Celular (CNBC/UC)

HMSP-ICT/0020/2013

Scouting the protein and PTM landscape of chronic obstructive pulmonary disease - New approaches for diagnosis and prognosis.
Rune Matthiesen
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

HMSP-ICT/0026/2013

"When the silence is interrupted". Histone methylation and cardiovascular disease: hypomethylating stress, EZH2-suppression, and endothelial cell homeostasis.
Maria Rita M A Azevedo e Castro
FARM-ID, Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento (FARM-ID)

HMSP-ICT/0027/2013

Subchondral bone markers as predictors of knee osteoarthritis severity, disease progression and articular cartilage regeneration response to innovative therapeutic approach with mesenchymal stem cell mobilization - the BiOA Project.
Helena Canhão
Sociedade Portuguesa de Reumatologia (SPR)

HMSP-ICT/0029/2013

Criação e caracterização de células estaminais pluripotentes induzidas derivadas de doentes de Huntington
Ana Cristina Carvalho Rego
Centro de Neurociências e Biologia Celular (CNBC/UC)

HMSP-ICT/0030/2013

Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis - Molecular Mechanisms and Clinical Implications
LUÍS FILIPE FERREIRA MOITA
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0032/2013

Accurate dose-response and target determination for metastatic liver cancer radiotherapy
Joep Stroom
Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (FC Champalimaud)

HMSP-ICT/0033/2013

Development of multi-target antimicrobial agents for the treatment of bacterial and fungal infections.
Maria Adelaide de Pinho Almeida
Universidade de Aveiro (UA)

HMSP-ICT/0034/2013

Targeting Germinal Centre Dysregulation in Allergy
Luis Ricardo Silva Graca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0035/2013

Metabolic Syndrome and Non-Alchoolic Fatty Liver Disease: Bile Acids as metabolic regulators and biomarkers
João Carlos Moura Bordado
Instituto de Ciências e Tecnologia de Polímeros (ICTPOL)

HMSP-ICT/0036/2013

Mycobacterium tuberculosis fitness - genetic and transcriptional adaptations to diabetic patients
Margarida Correia-Neves
Universidade do Minho (UM)

HMSP-ICT/0037/2013

Childhood obesity and later NCD Risk - from finding the causes to prevention
Ana Isabel Gomes Rito
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

HMSP-ICT/0039/2013

CardioRegen: Integrative studies from the embryo to Scalable Multipronged Generation of hESC-derived Myocardial progenitors for heart repair
José António Henriques de Conde Belo
Faculdade de Ciências Médicas (FCM/UNL)

HMSP-ICT/0040/2013

Understanding neurodegeneration in Spinal Muscular Atrophy - exploring transcriptome conservation in fly and human disease models
Margarida Henriques da Gama Carvalho
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

HMSP-ICT/0041/2013

Development of Minimally Invasive Biofluid Analysis of Exosomal mRNA: HOXA9 as a Diagnostic and Prognostic Biomarker of Glioblastoma
Bruno Costa
Universidade do Minho (UM)

HMSP-ICT/0042/2013

Prospective, randomized, unblinded, multi-center, phase II, futility design trial of antiplatelets versus anticoagulation in patients with undetermined stroke etiology with NT-proBNP equal or greater than 912 pg/mL
Ana Catarina Gaspar Fonseca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0043/2013

Identification of peripheral retinal lesions as biomarkers for diabetic retinopathy progression
Maria Luisa Ferreira Soares e Silva Reis Ribeiro
Associação para a Investigação Biomédica e Inovação em Luz e Imagem (AIBILI)

HMSP-ICT/0045/2013

New Dimensions in Vaccine Studies: The Case of Influenza
Maria Gabriela Miranda Gomes
Fundação Calouste Gulbenkian (FCG)

HMSP-ICT/0048/2013

Chemogenomic Approach to tRNA Synthetase Inhibitors as Novel Antimalarials
Maria Alexandra da Silva Paulo
FARM-ID, Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento (FARM-ID)

HMSP-ICT/0054/2013

Cerebral small vessel disease: new tools for preclinical risk assessment and preventive management
Elsa Azevedo
Faculdade de Medicina da Universidade do Porto (FM/UP)

HMSP-ICT/0056/2013

Genetic and molecular basis of skin pigmentation: improving phototherapy for vitiligo.
Duarte Barral
Faculdade de Ciências Médicas (FCM/UNL)

HMSP-ICT/0057/2013

THERAPEUTIC AND MOLECULAR RESPONSES TO EPIGENETIC AGENTS IN MYELOID NEOPLASMS
Bruno Miguel de Carvalho Silva Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0058/2013

Mistranslation in fungal pathogenesis and drug resistance
Manuel António Silva Santos
Universidade de Aveiro (UA)

HMSP-ICT/0061/2013

ANGIOGENIC BIOMARKERS IN PREECLAMPSIA RISK STRATIFICATION
Luis Guedes Martins
Centro Hospitalar Universitário do Porto (CHP/MS)

HMSP-ICT/0062/2013

Improving outcomes in women with HER2 positive metastatic breast cancer
Luis Antonio Marques da Costa
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

HMSP-ICT/0064/2013

From habit to compulsion: Dissecting the neural circuit basis of behavioral compulsions in Obsessive-Compulsive Disorder
Rui Costa
Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (FC Champalimaud)