This website was discontinued on 20/12/2022. Visit the new website at www.fct.pt.

Skip nav

R&D Projects

Proposals for Research Projects in all Scientific Domains - 2006

Painel de Avaliação de Ciências Biológicas - BCM/PRO - 2006

Coordination

René Medema
University Medical Center, Netherlands

Evaluation

Anastassis Perrakis
Netherlands Cancer Institute, Netherlands
Christian Schlötterer
Veterinärmedizinische Universität Wien, Austria
Manfred S. Weiss
EMBL Hamburg Outstation, Germany
Paul J. Coffer
University Medical Center, Netherlands
René Medema
Stavros Taraviras
University of Patras, Greece

Projects assigned

PTDC/BIA-BCM/64062/2006

Study of the intranuclear life of a nonsense transcript
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/BIA-BCM/64145/2006

Functional organization and dynamics of chromatin and its role in plant gene expression and cellular differentiation
Rita Sobral Moutinho Abranches
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/64148/2006

Genome-wide RNAi screen for host factors required for Fc-mediated phagocytosis, Salmonella invasion and bacterial killing
Otília Vieira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/BIA-BCM/64172/2006

Role of mitotic checkpoint in aneuploidy: a brain tumor model
Hassan Bousbaa
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/BIA-BCM/64177/2006

Screening, identification and characterisation of novel Arabidopsis thaliana meiotic mutants.
José António Melo da Costa Nunes
Instituto Superior de Agronomia (ISA/ULisboa)

PTDC/BIA-BCM/64192/2006

Chromosome cohesion and DNA repair in Arabidopsis.
José António Melo da Costa Nunes
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/64195/2006

Suppressors of oxidative stress-transcriptional defects of gim-mutant.
Lisete Celestina Perpétua Fernandes
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/64215/2006

Chromatin remodelling and abiotic stresses responses in rice.
Ana Paula Santos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/64226/2006

The role of the DNA damage checkpoint pathways involving ATM and ATR in telomere protection
Cláudio Enrique Sunkel Cariola
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/64252/2006

Molecular bases of rhizobia response to stress
Isabel Solange Martins de Oliveira
Universidade de Évora (UE)

PTDC/BIA-BCM/64275/2006

A Novel Lentiviral Target-Specific Strategy for Molecular and Gene Therapy
Joao Goncalves
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/BIA-BCM/64296/2006

Actin-scaffold proteins in synaptic plasticity: analysis of gene expression at the single-cell level.
Vasco Miguel Clara Lopes Galhardo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/64299/2006

Integrating the role of Yap1 and Yap8 in arsenic stress response of S. cerevisiae
Regina Menezes Echaniz
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/64438/2006

Identification and function analysis of transcription factors that regulate salt/cold responsive gene expression in rice
Nelson José Madeira Saibo
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/64442/2006

Bunyaviridae virus whole-genome sequence
Líbia Maria Marques Zé-Zé
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/BIA-BCM/64478/2006

Study of nonsense-mediated mRNA decay inhibition by a small upstream open reading frame
Ângela Inácio
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/BIA-BCM/64516/2006

Effect of Endocrine Disruptors in the freswater bivalve Anodonta cygnea
Claudia Maria Santos Alves de Carvalho Barrias
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/BIA-BCM/64824/2006

Aging and the stress response: new models and paradigms
Maria João Gameiro de Mascarenhas Saraiva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/65045/2006

Morphological and molecular studies in Hypericum species applied to herbals
Generosa Maria Manso Teixeira Xavier
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/BIA-BCM/65107/2006

Genetic approach of stem secondary growth in Arabidopsis: understanding the development of wood formation
Rita Teresa Pereira Teixeira
IMAR - Instituto do Mar (IMAR)

PTDC/BIA-BCM/65184/2006

Identification of brassinosteroid receptor BRI1/gene family in a gymnosperm (Pinus pinaster) and potential roles in vascular cell differentiation
Célia Maria Romba Rodrigues Miguel
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/BIA-BCM/65202/2006

Glycoprotein trafficking and post-translational processing in ovarian carcinoma
Júlia Carvalho Costa
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/65231/2006

Functional characterization of the electron transfer flavoproteins and their involvement in mitochondrial function and redox state of the cell
Rui Pedro Soares de Oliveira
Universidade do Minho (UM)

PTDC/BIA-BCM/65256/2006

Expression of antifreeze proteins (AFPs) as a method to improve cryopreservation ability in fish embryos
Vanesa Robles Rodríguez
Centro de Ciências do Mar (CCMar)

PTDC/BIA-BCM/65393/2006

Regulation of nucleoside, glutamate and GABA transporters by BDNF and adenosine receptors in astrocytes
Sylvie Duflot
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/BIA-BCM/65567/2006

Does P-cadherin expression interfere with E-cadherin function in invasive breast cancer cells?
Joana Cancela de Amorim Falcão Paredes
Universidade do Minho (UM)

PTDC/BIA-BCM/65593/2006

Oxidized hemoglobin is a pro-inflammatory agonist in endothelial cells
Gabriela Medeiros Silva
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/65634/2006

EvOC: A multidisciplinary approach to determine the biological function of osteocalcin isoforms
Vincent Laizé
Centro de Ciências do Mar (CCMar)

PTDC/BIA-BCM/65744/2006

Search of plant phenolic compounds exhibiting antioxidant activity and acting through the ubiquitin/proteasome pathway in neuronal cell models and animal models of Parkison's disease
Ricardo Manuel de Seixas Boavida Ferreira
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/65840/2006

Study of monocarboxylate transporters as potential therapeutic targets in solid tumors: physiological, biochemical and molecular approaches, using different biological systems.
Maria de Fátima Monginho Baltazar
Universidade do Minho (UM)

PTDC/BIA-BCM/65872/2006

Embryonic wound healing: a genetic approach
António Alfredo Coelho Jacinto
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/BIA-BCM/65874/2006

Interaction of aluminium with Na+/K+-ATPase and Ca2+-ATPase and relevance to neurotransmission impairment induced by aluminium
Virgília Sofia Almeida de Azevedo e Silva
Universidade de Aveiro (UA)

PTDC/BIA-BCM/65936/2006

Identification of red blood cell secreted proteins with cell growth bioactivity
Fernando Aguilar Arosa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/66145/2006

In the Cetartiodactyla "theatre" : Reconstruction of the ancestral karyotype and structural chromosome changes in interphase nuclei - a 3D translocation-model
Maria Filomena Lopes Adega
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/BIA-BCM/66241/2006

Molecular characterization of Yeast Apoptosis Effector Proteins
Björn Fredrik Johansson
Universidade do Minho (UM)

PTDC/BIA-BCM/66333/2006

ALMOND AS A MODEL FOR PRUNOIDEAE - AN INTEGRATIVE APPROACH TO THE TRANSCRIPTIONAL REGULATION OF FLOWER/SHOOT INDUCTION AND ABIOTIC STRESS RESPONSE
M Margarida Moutinho Girao de Oliveira
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/66345/2006

4D characterization of nuclear speckles and splicing factor dynamics
Joao Sanches
Instituto Superior Técnico (IST/ULisboa)

PTDC/BIA-BCM/66368/2006

Establishment and characterization of mosquito cell lines from the Culex pipiens complex (Diptera: Culicidae)
Aida Maria da Conceição Esteves Simões
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/BIA-BCM/66449/2006

Spatial and temporal organization of Staphylococcus aureus cell division
Mariana Luisa Tomás Gomes de Pinho
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/66486/2006

Neuronal control of bone homeostasis: expression and functions of Neuropetide Y -Y2 receptor in bone.
Meriem Lamghari Moubarrad
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/BIA-BCM/66798/2006

The role of protein phosphatases in stress signalling in Vitis vinifera plants
Etelvina Figueira
Universidade de Aveiro (UA)

PTDC/BIA-BCM/66976/2006

Identification and characterization of novel transthyretin-protein interactions - contributions to elucidate TTR biology
Maria Rosário Almeida
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/67035/2006

Investigation of runx3 structure and function in zebrafish.
Natércia Conceição
Centro de Ciências do Mar (CCMar)

PTDC/BIA-BCM/67058/2006

A novel insight into CFTR Phosphorylation: implications for its processing, trafficking and function
Carlos Miguel Ribeiro da Silva Farinha
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/BIA-BCM/67223/2006

The role of the human blood-testis barrier on the fluid seminiferous secretion
Augusta Maria Ferreira Rebelo da Costa
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/BIA-BCM/67261/2006

Identification of anti-checkpoint proteins at fission yeast telomeres
Miguel Godinho Ferreira
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/67437/2006

More than putting cells into place during development: cell-extracellular matrix interactions in myogenesis.
Solveig Thorsteinsdottir
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/BIA-BCM/67438/2006

Cardosins Intracellular Trafficking Pathways
José Pissarra
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/BIA-BCM/67504/2006

Role of ribonucleases on Enterococcus faecalis V583 virulence regulation
Paulo Emanuel de Oliveira Marujo
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/BIA-BCM/67609/2006

Mitochondrial directed mutagenesis in cell cultures
Rafael Montiel Duarte
Universidade dos Açores (UAçores)

PTDC/BIA-BCM/67653/2006

Dissection of Yap4 and Yap6 protein-protein interactions as a means to understand their functional role under conditions of hyperosmolarity
Claudina Amélia Marques Rodrigues Pousada
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/67793/2006

Role of aquaporin-4 in neonatal brain edema associated to hypoxia/ischemia and hyperbilirubinemia
Rui Fernando Marques da Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/BIA-BCM/67885/2006

STEMSOURCE - Converting Stem Cell Potential into Clinical Applications: Systematic Study of Different Cell Sources
Rui L Reis
Universidade do Minho (UM)

PTDC/BIA-BCM/67894/2006

The induction of regulatory T cells from naive precursors: how is the cell fate controlled by the activation threshold?
Luis Ricardo Silva Graca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/BIA-BCM/67922/2006

Linking Fibrillogenesis and the Apoptosis Induced by Amyloid β Peptides
Cecília Maria Pereira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/BIA-BCM/67948/2006

Water Deficit Recovery in Medicago truncatula: a transcriptomic and physiological integrative approach
DULCE MARIA METELO FERNANDES DOS SANTOS
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/67964/2006

Molecular characterization of the mating type locus of the unconventional basidiomycetous yeast Rhodosporidium (Rhodo-MAT)
Álvaro Luis Afonso Moreira Rato da Fonseca
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/BIA-BCM/68019/2006

PROMISSOY - Immunogenicity control and modulation of newly developed highly promising soy-based biomaterials.
Alexandra P Marques
Universidade do Minho (UM)

PTDC/BIA-BCM/68030/2006

Regulatory mechanisms of signalling cascades in plant cells - modulating the actin cytoskeleton in polarized cells
Rui Malhó
Instituto de Ciência Aplicada e Tecnologia - Faculdade de Ciências da Universidade de Lisboa (ICAT/FC/ULisboa)

PTDC/BIA-BCM/68097/2006

STIMCELL - Development of novel bioreactor systems for controlled biomechanical conditioning of bone and cartilage cells
Rui L Reis
Universidade do Minho (UM)

PTDC/BIA-BCM/68471/2006

Characterization of the mechanism through which multipotent mesenchymal stromal cells induce/participate in remyelination.
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/68814/2006

Ontogenic resetting of chromocenter structure in Arabidopsis: centromere identity and transcription of non-coding centromeric DNA
Maria Margarida Cabrita Xavier Delgado
Instituto Superior de Agronomia (ISA/ULisboa)

PTDC/BIA-BCM/68857/2006

CELL SHAPE AND POLARITY: THE ROLE OF Tetrahymena TUBULIN COFACTOR E IN MICROTUBULE BIOGENESIS
Maria Helena Antunes Soares
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/68870/2006

Fat4Bone - Development of alternative cell sources from adipose tissue and advanced in vitro culturing systems to obtain bone tissue engineered substitutes with high in vivo functionality
Maria Manuela Estima Gomes
Universidade do Minho (UM)

PTDC/BIA-BCM/68882/2006

NEW INSIGHTS INTO THE ROLE OF ANDROGENS AND PRL IN FEMALE BREAST PHYSIOLOGY
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/BIA-BCM/69252/2006

Purinergic Signalling in Human Sertoli Cells
Henrique Silva
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/BIA-BCM/69256/2006

Characterization of the transcriptional activation of the quiescent zygotic genome after oocyte fertilization.
Rui Gonçalo Viegas Russo da Conceição Martinho
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/69352/2006

FUNCTIONAL ANALYSIS OF THE TRANSCRIPTION REGULATOR Haa1: ROLE IN Saccharomyces cerevisiae RESPONSE TO ACETIC ACID AND COPPER
Isabel Maria de Sá Correia Leite de Almeida
Instituto Superior Técnico (IST/ULisboa)

PTDC/BIA-BCM/69463/2006

Dual control of inflammation by H2O2: steady-state titration, synergetic activation of NF-kappaB, and CO production.
Fernando José Nunes Antunes
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/BIA-BCM/69543/2006

What is the role of the “female” hormone (estradiol) in a male process (spermatogenesis)?
José Eduardo Brites Cavaco
Universidade da Beira Interior (UBI)

PTDC/BIA-BCM/69580/2006

Characterization of human kinechore subcomplexes required for accurate chromosome segregation and spindle checkpoint function
Elsa Logarinho
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/BIA-BCM/69912/2006

Study of the role of vertebrate ADTK1, a novel dual-specificity Ser/Thr/Tyr kinase gene family
José António Henriques de Conde Belo
Universidade do Algarve (UAlg)

PTDC/BIA-BCM/70110/2006

STEMFACTOR - Unveiling the Cross-talking Mechanisms of the Regulation of Neuronal and Glial Cells Survival, Proliferation and Differentiation by Mesenchymal, Adipose Tissue Derived and Umbilical Cord Stem Cells
Nuno Jorge Carvalho de Sousa
Universidade do Minho (UM)

PTDC/BIA-BCM/70361/2006

Yap1 and Yap2 cross talk in cadmium detoxification in Saccharomyces cerevisae
Claudina Amélia Marques Rodrigues Pousada
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/70597/2006

Molecular characterization of tissue regeneration in sea star model system - toward the discovery of new regeneration factors and their potential medical applications
Ana Varela Coelho
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/70662/2006

LUSOVENOME - Proteomic study of Portuguese snake venom.
Stéphane Pierre Besson
COFAC, Cooperativa de Formação e Animação Cultural, CRL (COFAC)

PTDC/BIA-BCM/70745/2006

Whole Genome Mapping of Small RNAs from Arabidopsis Pollen to analyze their involvement in Genome and Transcript Control during Sexual Plant Reproduction
Jörg Dieter Becker
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/70783/2006

Novel patterns and mechanisms of regulation of intracellular levels of glycerol in Saccharomyces cerevisiae through its high affinity transporter (Stl1p) regulation
Cândida Manuel Ribeiro Simões Lucas
Universidade do Minho (UM)

PTDC/BIA-BCM/71117/2006

Microarray-based surveying of Chlamydia trachomatis chromosomal mosaics
JOÃO PAULO DOS SANTOS GOMES
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/BIA-BCM/71131/2006

Virulence factors expressed by the parasitic nematode Steinernema carpocapsae
Nelson Simões
Universidade dos Açores (UAçores)

PTDC/BIA-BCM/71241/2006

Probing the Functional Importance of Pectin Methylesterase Inhibitors During Plant Development
Philip Anthony Patrick Jackson
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/71560/2006

Cellular Decisions in the Immune System
Fernão Rodrigues Vistulo de Abreu
Universidade de Aveiro (UA)

PTDC/BIA-BCM/71595/2006

Real-time imaging of Notch signalling with single-cell resolution during neurogenesis
Maria Leonor Tavares Saúde
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/71602/2006

The role of the gene terra in the coordination of the left-right establishment and somitogenesis
Maria Leonor Tavares Saúde
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/71619/2006

The molecular mechanisms by which Hox genes control development of the axial skeleton
Moises Mallo
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/71663/2006

Identification of ligands for γδ T cell receptors: a genomics/ transcriptomics approach.
Bruno Miguel de Carvalho Silva Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/BIA-BCM/71674/2006

Molecular control of actin dynamics and change in cell shape in the morphogenetic furrow during Drosophila eye development.
Florence Janody
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/71839/2006

Macrophage apoptosis in the control of Mycobacterium tuberculosis
Rui Appelberg Gaio Lima
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/71920/2006

The role of SR-BI in malaria infection
Miguel Prudêncio
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/BIA-BCM/72118/2006

Crosstalk between yeast cell metabolism and active cell death
Paula Cristina da Costa Alves Monteiro Ludovico
Universidade do Minho (UM)

PTDC/BIA-BCM/72225/2006

Role of Arabidopsis thaliana STP13, a putative monosaccharide transporter, in the defence response against the necrotrophic pathogen Botrytis cinerea
Herlander Anselmo Queirós Pereira Azevedo
Universidade do Minho (UM)

PTDC/BIA-BCM/72291/2006

Regulation of the proteasome by brain-derived neurotrophic factor (BDNF)
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/BIA-BCM/72524/2006

Differential toxicogenomic responses involved in hepatic cholestasis and steatosis: molecular mechanisms of bile acids therapy
Carlos Palmeira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/BIA-BCM/72578/2006

Interactome analysis
André Xavier de Carvalho Negrão Valente
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/BIA-BCM/72643/2006

Antigenotoxic features of natural compounds: effects on DNA repair mechanisms
Olga Maria Fernandes Pereira Coutinho
Universidade do Minho (UM)

PTDC/BIA-BCM/72682/2006

Discovery of new ligands that bind cell-surface components associated with breast cancer by phage display
Maria Jose Miranda de Castro
Universidade do Algarve (UAlg)

PTDC/BIA-BCM/72761/2006

Primary molecular events, alterations of neuronal bioenergetics and implications of the actin cytoskeleton impairment in the toxicity of reactive oxygen and nitrogen species induced in neurodegenerative processes.
Teresa Paula Martins Tiago
Centro de Ciências do Mar (CCMar)

PTDC/BIA-BCM/72898/2006

Molecular and genetic characterization of the ion channels underlying calcium and chloride roles on pollen tube growth and morphogenesis in Arabidopsis thaliana
Erwan MICHARD
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/72966/2006

MONOTRAF - Posttranslational Regulation and Trafficking of Monocarboxylates Permeases in Yeast
Sandra Cristina Almeida Paiva
Universidade do Minho (UM)

PTDC/BIA-BCM/72975/2006

New proteins involved in the intracellular targeting of APP
Odete A B da Cruz e Silva
Universidade de Aveiro (UA)

PTDC/BIA-BCM/73053/2006

Molecular Tools for Avoidance Behaviour Assessment in Terrestrial Ecotoxicology - IMOL
Amadeu Mortágua Velho da Maia Soares
Universidade de Aveiro (UA)

PTDC/BIA-BCM/73146/2006

Molecular mechanisms of organelle motility
Miguel Seabra
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/73195/2006

Regulation Of Centriole Biogenesis And Function: An Integrative Approach
Monica Bettencourt Carvalho Dias
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/73232/2006

AraOxi - Functional characterization of Arabidopis thaliana TOB1 and OSR1, two putative ROS homeostasis-associated genes
Rui Manuel Peixoto Tavares
Universidade do Minho (UM)

PTDC/BIA-BCM/73371/2006

Which characteristics define functional sperm? Isolation of subpopulations of human sperm with distinct properties and implications for reproduction
João RamalhoSantos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/BIA-BCM/73401/2006

Nuclear Architecture in Rodents. A functional and dynamic model for nucleus: patterns of chromosome territories evolution, replication and transcripcion dynamic profiling, and disease.
RAQUEL MARIA GARCIA DOS SANTOS CHAVES
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/BIA-BCM/73616/2006

MOLECULAR DETERMINANTS FOR ENTRY, MAINTENANCE AND EXIT FROM QUIESCENCE (G0) IN YEAST: IMPLICATIONS FOR AGING RESEARCH
António Pedro Barros Gomes
Universidade do Minho (UM)

PTDC/BIA-BCM/73676/2006

Identification and characterization of quorum sensing systems involved in bacterial inter-species communication
Karina Xavier
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/73693/2006

Molecular mechanisms of melanocortin 5 receptor (MC5R) signal transduction
Alexandra Maria Monteiro Gouveia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/BIA-BCM/74583/2006

Dissecting the developmental genetic basis of evolutionary novelty
José Élio da Silva Sucena
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/76782/2006

Functional characterization of senescence-associated genes in Arabidopsis thaliana
Maria Teresa Correia Guedes Lino Neto
Universidade do Minho (UM)

PTDC/BIA-BCM/78272/2006

The fundamentals of nitric oxide bioactivity in hippocampus: dynamics and glutamatergic regulation
João António Nave Laranjinha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/BIA-BCM/80809/2006

The mechanism of function of Erk5 in orchestration of cell cycle, survival and differentiation in interneurons in mice
Sukalyan Chatterjee
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-BCM/81401/2006

Transcriptional regulation of tissue repair in vertebrates.
Rajeeb Kumar Swain
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/BIA-PRO/64020/2006

Characterization of hybrid tetramers of phenylalanine hydroxylase: investigation of negative complementation in a human enzyme.
Ana Paula Costa Santos Peralta Leandro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/BIA-PRO/64354/2006

Structural, mechanistic and functional studies of membrane calcium channels
Ilídio Joaquim Sobreira Correia
Universidade da Beira Interior (UBI)

PTDC/BIA-PRO/64937/2006

The Human Mitochondrial Carrier Carnitine Acylcarnitine Translocase (hCACT): Functional and Structural Characterisation
Maria de Fátima Vieira Ventura
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/BIA-PRO/65299/2006

Structural determinants of the biochemical properties of xylose transporters - improving xylose transport in yeasts
PAULA MARIA THERIAGA MENDES BERNARDO GONÇALVES
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/BIA-PRO/66049/2006

Structural aspects of melanocortin 5 receptor (MC5R) responsible for its cell surface expression
Alexandra Maria Monteiro Gouveia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/BIA-PRO/66517/2006

Islet amyloid polypeptide and type 2 diabetes: molecular mechanism of fibril formation and the role of lipid membranes
Manuel José Estevez Prieto
Instituto Superior Técnico (IST/ULisboa)

PTDC/BIA-PRO/66557/2006

Investigating the energy transduction Q-cycle mechanism in complexes of respiratory chains
Manuela Alexandra de Abreu Serra Marques Pereira
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/66711/2006

Understanding molecular mechanisms in ABC transporters. Structural Bioinformatics approaches
Claudio Manuel Simões Loureiro Nunes Soares
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/66833/2006

A structural genomics approach to membrane transport proteins from Archaea
Margarida Archer Frazão
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/67105/2006

Identification and characterization of the supercomplexes from the bacterial aerobic respiratory chain of Escherichia coli and Bacillus subtilis
Ana Margarida Nunes Portugal Carvalho Melo
Instituto de Investigação Científica Tropical,I.P. (IICT) (IICT/MNE)

PTDC/BIA-PRO/67107/2006

Iron metabolism in sulphate reducing bacteria
Ligia M Saraiva
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/67240/2006

Iron Metabolism Study in Deinococcus radiodurans- Novel strategies
Celia Romao
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/67263/2006

Microbial enzymes involved in superoxide and nitric oxide reduction
Miguel Nuno Sepúlveda de Gouveia Teixeira
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/68486/2006

Quinol oxidation by membrane cytochromes c widely implicated in bacterial respiration - structural studies of the model NrfHA complex
Inês Antunes Cardoso Pereira
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/69446/2006

The inhibitory function of the Scavenger-type receptors CD5 and CD6 in lymphocyte signaling
Monica Alexandra do Amaral Castro
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-PRO/69732/2006

Structure and function of novel carbohydrate-binding modules and cohesin-dockerin protein complexes from Clostridium thermocellum
Carlos MGA Fontes
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/BIA-PRO/69853/2006

Membrane-assisted pathogenic conversion of Prion Protein (PrP)
Miguel Castanho
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/BIA-PRO/70102/2006

Structural and functional understanding of the implications of frataxin mutations in the neurodegenerative disorder Friedreich's ataxia
Cláudio Emanuel Moreira Gomes
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/70429/2006

Towards biohydrogen production - study of a high-activity, oxygen-resistant bacterial hydrogenase
Pedro Manuel Henriques Marques Matias
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/70603/2006

Identification of the receptor(s) for West Nile virus in the brush border membrane of Culex mosquitoes
Aida Maria da Conceição Esteves Simões
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/BIA-PRO/71105/2006

A new biological source of fibrinolytic and trombolytic enzymers: nematode serine proteases
Nelson Simões
Universidade dos Açores (UAçores)

PTDC/BIA-PRO/71465/2006

Characterisation of CymA: a focal protein in anaerobic respiration by Shewanella - Reinforcement of the team
Ricardo Saraiva Loureiro de Oliveira Louro
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/71636/2006

The modular structure of protein networks: evolutionary study and application to bioinformatics method development
José Bartholo Pereira Leal
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-PRO/72294/2006

Effect of pH and other electrostatic factors on protein structure and function: molecular simulation studies using specialized methods
António Manuel Simões Carrão Albuquerque Baptista
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-PRO/72457/2006

BIOCHEMICAL, STRUCTURAL AND GENETIC CHARACTERIZATION OF THE MITOTIC KINETOCHORE
ÁLVARO AUGUSTO MARQUES TAVARES
Fundação Calouste Gulbenkian (FCG)

PTDC/BIA-PRO/72540/2006

Design of selective inhibitors for human pro-coagulant proteases
Miguel Xavier Jesus Josefat Fernandes
Universidade da Madeira (UMA)

PTDC/BIA-PRO/72560/2006

Prion Diseases: A Biophysical Approach to the Pathological Protein Conformer
Eduardo Pinho Melo
Universidade do Algarve (UAlg)

PTDC/BIA-PRO/72986/2006

Understanding the structure-function relationship of atypical aspartic proteinases from Arabidopsis thaliana.
Carlos José Fialho Costa Faro
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/BIA-PRO/73128/2006

Computer aided molecular modeling of phosphodiesterase 3 inhibitors
Miguel Xavier Jesus Josefat Fernandes
Universidade da Madeira (UMA)

PTDC/BIA-PRO/73129/2006

Structural and functional investigation of protein phosphatase 1 targeting and regulation
Edgar Figueiredo da Cruz e Silva
Universidade de Aveiro (UA)

PTDC/BIA-PRO/73608/2006

Studying biological iron containing cofactors by Mössbauer spectroscopy. Development of a global iterative analysis program.
Pedro Tavares
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/BIA-PRO/73659/2006

Studies of Potential Targets for Anti-HIV-1 Chemotherapy
Pedro Manuel Azevedo Alexandrino Fernandes
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/BIA-PRO/74498/2006

Characterization of a new family of heme-containing sensor proteins from Geobacter sulfurreducens
Carlos Alberto Gomes Salgueiro
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/BIA-PRO/80486/2006

Structural characterization of mRNA localization mechanisms
Jose Pedro da Silva Trincao
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/BIA-PRO/81483/2006

Structural-Function Relationships in Prokaryotic Multicopper Oxidases
Lígia Maria Oliveira Martins
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/BIA-BCM/64224/2006

Molecular dissection of the spindle assembly checkpoint proteins in Drosophila
Cláudio Enrique Sunkel Cariola
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/64745/2006

Implementation of a Nacional Facility for DNA Microarrays: Phase II
Manuel António Silva Santos
Universidade de Aveiro (UA)

PTDC/BIA-BCM/64771/2006

The molecular mechanisms of protein import into mammalian peroxisomes: a Pex5p- and Pex19p-centered perspective
Jorge Eduardo da Silva Azevedo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/66106/2006

Functional Dissection of Cell Division and Aneuploidy with Laser Microsurgery in Living Cells
Helder Jose Martins Maiato
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/66818/2006

HFE as a multitask protein: genomic and biochemical analysis
Maria Angela Brito de Sousa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/BIA-BCM/69448/2006

Elucidation of ceramide-induced apoptosis: modulation of Protein Kinase C isoforms
Maria Manuela Sansonetty Goncalves Corte Real
Universidade do Minho (UM)

PTDC/BIA-BCM/69841/2006

Role of integrin-linked-kinase and associated molecules in myelination and remyelination of the nervous system
Joao Carlos Bettencourt de Medeiros relvas
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-BCM/71789/2006

Role of cortactin in the cellular trafficking of AMPA-type glutamate receptors
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/BIA-BCM/71932/2006

Biogenesis of peroxisomes: Identification and characterization of the molecular machinery required for the growth and division of peroxisomes
Michael Schrader
Universidade de Aveiro (UA)

PTDC/BIA-BCM/72251/2006

Developing new tools for studying mRNA mistranslation
Gabriela Moura
Universidade de Aveiro (UA)

PTDC/BIA-PRO/64437/2006

Search for the molecular basis of transthyretin involvement in the biology of the nervous system.
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-PRO/70455/2006

PROFILING ATAXIN-3 UBIQUITIN PROTEASE ACTIVITY: A BIOCHEMICAL AND STRUCTURAL APPROACH
Sandra de Macedo Ribeiro
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-PRO/70627/2006

MACROMOLECULAR ANTI-COAGULANTS: UNVEILING THE MOLECULAR DETAILS OF THROMBIN INHIBITION
Pedro José Barbosa Pereira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/BIA-PRO/72838/2006

Searching for high level rules in protein folding and unfolding: from amyloid diseases to protein structure prediction
Rui Brito
Centro de Neurociências e Biologia Celular (CNBC/UC)