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R&D Projects

Open Call for Research and Development Projects in Clinical Research

Painel de Avaliação de Projectos de Investigação Clínica - 2007

Coordination

Fernando Lopes da Silva

Evaluation

Armando Brito Sá
João António Catita Garcia Pereira
Jorge Soares
José Henrique Dias Pinto de Barros
Marta Hansen Lima Basto Correia Frade
Rui Manuel Martins Victorino

Projects assigned

PIC/IC/82712/2007

Lymphoid tissues in HIV-2 infected patients
Ana Espada de Sousa
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82714/2007

Tn antigen expression in gastric and bladder cancer: clinical-biological correlation with the dendritic cell immune response.
Paula Alexandra Quintela Videira
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/82719/2007

Identification of novel antigens in Mycobacterium tuberculosis clinical strains
Anabela Medo Miranda
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/82734/2007

The relationship of circulating biomarkers of apoptosis and endothelial function with the plaque composition using VH IVUS
Maria Teresa Ferreira Marques Pinheiro
Instituto Superior Técnico (IST/ULisboa)

PIC/IC/82735/2007

The ethiology and pathogenesis of venous thrombosis in the Portuguese “in risk” population: From clinical manifestations to identification of hereditary risk and protective factors as well as exogenous or ambiental factors
Dezso David
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/82737/2007

Suicide prevention and improved management of common mental health disorders : combined intervention of psychoeducation for patients and training for primary care practitioners
RICARDO DUARTE MIRANDA DE GUSMÃO
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/82738/2007

Total hip replacement failures in Portugal - pilot clinical investigation in two hospitals
Mário Barbosa
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PIC/IC/82739/2007

Assessment, translation and control of human pain: An integrated intelligent system of dedicated biomedical equipment and computer aided decision for closed-loop control of analgesic therapies
Joaquim Manuel Vieira da Silva Viana
Universidade da Beira Interior (UBI)

PIC/IC/82740/2007

FAMILIAL MIGRAINE - clinical and genetic study
José Maria Pereira Monteiro
Centro de Estudos de Cefaleias (CEC)

PIC/IC/82741/2007

Trigemino-autonomic cephalalgias - clinical and ethiopathogenic study
José Maria Pereira Monteiro
Centro de Estudos de Cefaleias (CEC)

PIC/IC/82746/2007

Lupus and its compensation in unaffected relatives by T-cell regulation
Constantin Fesel
Fundação Calouste Gulbenkian (FCG)

PIC/IC/82748/2007

Carotid Atherosclerosis Disease Diagnosis with 3D Ultrasound
Joao Sanches
Instituto Superior Técnico (IST/ULisboa)

PIC/IC/82752/2007

RETINOIDS FOR PSORIASIS AND CANCER: Molecular Mechanisms of Pharmacological and Toxicological Effects and Combination Therapies with Antiestrogenic Drugs
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PIC/IC/82754/2007

Transdermal drug delivery with photoacoustic waves
Luís Guilherme da Silva Arnaut Moreira
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PIC/IC/82755/2007

Direct action of diuretic drugs and aldosterone on kidney potassium channels
Ana Isabel Dias Bicho dos Santos
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PIC/IC/82760/2007

Slow and Rapid Progression Parkinson´s Disease: Molecular Determinants and Biomarkers
Tiago Outeiro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82765/2007

Respiratory Rehabilitation in Amyotrophic Lateral Sclerosis: clinical and biochemical impact
Mamede de Carvalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82766/2007

The role of microRNAs in colorectal cancer: profiling and cellular functions
Cecília Maria Pereira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PIC/IC/82772/2007

Neurotoxicity and neuroprotection in the chronic use of antidepressive drugs
Maria Teresa Burnay Summavielle
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/82775/2007

Markers of oxidative stress in HIV-1 infected naïve patients before and during therapeutic regimens with efavirenz or protease inibitors
Maria Emilia Carreira Saraiva Monteiro
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/82780/2007

Portuguese language version of Affective Neurosciences Personality Scales: Towards normative assessment of personality traits in health and disease (relevance of emotion based personality traits for treatment outcome evaluation in drug addiction)
Carlos Manuel da Cruz Farate
Instituto Superior Miguel Torga (ISMT)

PIC/IC/82784/2007

A follow-up model for prevention of gastric adenocarcinoma based on phenotype and genotype: a multicentre prospective study
Mario Dinis Ribeiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/82787/2007

Elderly Health condition and quality of life: A transcultural study
MANUEL JOSÉ LOPES
Universidade de Évora (UE)

PIC/IC/82796/2007

Neuropsychological predictors of the outcome in non-demented subjects with cognitive complaints
Alexandre Valério de Mendonça
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82801/2007

PAIN BRAIN MATRIX IN PATIENTS WITH MULTIPLE SCLEROSIS AND IN PATIENTS WITH MIGRAINE: A FUNCTIONAL AND PERFUSION MAGNETIC RESONANCE IMAGING STUDY.
Deolinda Maria Valente Alves Lima Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/82804/2007

Clinical applications of the Novel Silicon-containing Bonelike® (BonelikeR-Si) synthetic bone graft for Maxillofacial and Orthopaedic Surgery
José Domingos Santos
Medmat Innovation - Materias Médicos, Lda. (Medmat)

PIC/IC/82807/2007

Zebrafish as a transgenic in vivo model to analyse osteoporosis-related gene function and regulation - OSTEOFISH
Leonor Cancela
Centro de Ciências do Mar (CCMar)

PIC/IC/82810/2007

Clinical and Molecular characterization of congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency
lurdes lopes
Hospital de Dona Estefânia (HDE/CHLC)

PIC/IC/82812/2007

Bridging the extremes: how chronic granulomatous disease can help us understand rheumatoid arthritis
Maria Margarida Souto Carneiro
Fundação Calouste Gulbenkian (FCG)

PIC/IC/82815/2007

“DNA mimics” - Development and application of DNA mimics for the rapid identification of pathogens
Nuno Filipe Azevedo
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PIC/IC/82818/2007

From Human Proteomics to Identification of Therapeutic Targets for Lung Hypoplasia
Jorge Manuel Nunes Correia Pinto
Universidade do Minho (UM)

PIC/IC/82819/2007

Humoral and tissue Doppler characterization of the failing heart of infants with congenital diaphragmatic hernia
Jorge Manuel Nunes Correia Pinto
Universidade do Minho (UM)

PIC/IC/82820/2007

Health benefits of blue lupin (Lupinus angustifolius) on cardiovascular disease prevention: mechanisms of action and biomarkers evaluation
Ofelia Pereira Bento
Universidade de Évora (UE)

PIC/IC/82821/2007

Prognostic Signatures in Colorectal Cancer (PSCC)
Luis Antonio Marques da Costa
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82822/2007

Prognosis and prevention in a few inherited diseases existing in the Portuguese population
OLGA ALCINA MARTINS DE OLIVEIRA AMARAL
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/82826/2007

Congenital cytomegalovirus infection: evaluation of a new methodology for newborn screening
Maria Teresa Possante Marques
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/82829/2007

Evaluation of the utility of new rapid tests to improve the diagnosis of tuberculosis in Portugal
Margarida Correia-Neves
Universidade do Minho (UM)

PIC/IC/82830/2007

Implications of Claspin mutations in DNA replication, cell cycle checkpoint responses and oncogenesis
Teresa Maria Caldeira Martins
Instituto Português de Oncologia de Francisco Gentil, Centro Regional de Oncologia de Coimbra (IPO Coimbra)

PIC/IC/82833/2007

Do low doses of ionizing radiation stimuate tumoral re-growth and metastasis?
Susana Constantino Rosa Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82835/2007

Non invasive monitoring of blood glucose in diabetes patients
Rui Guerra
Universidade do Algarve (UAlg)

PIC/IC/82840/2007

National Insomnia Network
Maria Teresa de Aguiar dos Santos Paiva
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82842/2007

Attachment of HIV to target cells and its inhibitions: clinical and therapeutic implications
José Miguel Azevedo Pereira
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PIC/IC/82847/2007

Ionizing radiation and malignant melanoma: a clinical and biomolecular approach
Margarida Alexandra Patrício Goulart de Medeiros
Instituto Tecnológico e Nuclear (ITN)

PIC/IC/82850/2007

Potential clinical relevance of human neurotropic polyomavirus JC-related molecular biomarkers of colorectal carcinogenesis in a Portuguese population
Luis Almeida
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/82857/2007

HCV-specific immune response in hepatitis C chronically infected patients during anti viral therapy. The role of HCV-specific CD8+. Looking for new molecular targets to improve therapy efficacy.
Paula Cristina Santos Luxo Maia
Universidade de Coimbra (UC)

PIC/IC/82859/2007

Interference of Mycobacterium tuberculosis with the endocytic/antigen presentation pathways on macrophages and dendritic cells from healthy and immunocompromised donnors
ELSA MARIA RIBEIRO DOS SANTOS ANES
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PIC/IC/82860/2007

Clinical decision support systems in improvement management and survival of patients with colorectal cancer
Lúcio Lara Santos
Instituto Português de Oncologia de Francisco Gentil, Centro Regional de Oncologia do Porto (IPO Porto)

PIC/IC/82862/2007

Haemophilus influenzae infection: surveillance and characterization of antibiotic resistance mechanisms and alterations of virulence in clinical strains isolated after the Hib vaccine introduction in National Vaccination Plan.
MARIA PAULA RAMALHO BAJANCA LAVADO
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/82863/2007

Evaluation of the prevalence of Streptococcus mutans and Streptococcus sobrinus in Portuguese schoolchildren
Paula Ferreira
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/82864/2007

WHITE-COAT HYPERTENSION. BLOOD PRESSURE REACTIVITY TO STRESSFUL HEMODYAMIC AND PSYCHOLOGICAL STIMULI
Jorge Manuel Silva Junqueira Polonia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/82865/2007

Impact of Non-Erosive Reflux Disease on Inflammation-Metaplasia-Dysplasia-Adenocarcinoma Sequence Associated With Gastroesophageal Reflux Disease
Maximino José Correia Leitão
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/82868/2007

Nanosensor for assessing the risk of a Cardiovascular Disease Risk Nanosensor (Cardiosensor)
Teresa Alexandra Peixoto Rocha Santos
Instituto Piaget, Cooperativa para o Desenvolvimento Humano, Integral e Ecológico CRL (IPiaget)

PIC/IC/82869/2007

Comparison between markers of hypoxia/reoxygenation and inflammation in hypertensive patients with obstructive sleep apnoea treated with angiotensin AT1- receptor antagonists or angiotensin converting enzyme inhibitors
Maria Emilia Carreira Saraiva Monteiro
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/82873/2007

Analysis of the interactions of group B streptococci with the plasminogen activation system and characterization of its role on the development of human invasive infections
Paula Ferreira
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/82875/2007

In office dental whitening, clinical eficacy and safety and effects on dental restorative materials
António Duarte Sola Pereira da Mata
Faculdade de Medicina Dentária da Universidade de Lisboa (FMD/ULisboa)

PIC/IC/82877/2007

Effects of gustative stimulants on salivary secretion efficacy and dental erosion on oncological patients
Sofia de Mello Lima Teixeira Santos Arantes e Oliveira
Faculdade de Medicina Dentária da Universidade de Lisboa (FMD/ULisboa)

PIC/IC/82878/2007

Genetic Testing and Counselling for Late-Onset Neurological Diseases: from quality assurance to the clinical, psychological, ethical and social impact
Jorge Sequeiros
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/82879/2007

Numerical and experimental studies of blood flow inside coronary artery stents: left main bifurcation coronary lesions the pitfall of interventional cardiology
João Bernardo Lares Moreira de Campos
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PIC/IC/82880/2007

Breast Cancer MicroRNAs as Clinical Tools for Diagnosis and Prognosis of the Portuguese Population
Patrícia Matos Cruz da Silva Pereira
Universidade de Aveiro (UA)

PIC/IC/82883/2007

Development of multiple approaches for the screening of lysosomal storage disorders - tandem mass spectrometry, biochemical characterisation and molecular analysis
Sandra Catarina da Conceição Alves
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/82887/2007

Mapping and identification of genes involved in familial thyroid cancer using the new SNP-Array technology
Branca Maria Prudêncio Limón Cavaco
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82889/2007

Antibody Neutralization in Human Immunodificiency Virus Type 2 (HIV-2) Infection: Production and Characterization of Human Monoclonal Antibodies Neutralizing HIV-2 Infection
Helena Barroso
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PIC/IC/82890/2007

Unravelling the role of G protein-coupled receptor kinases (GRKs) in Crohn's disease: from predictive biomarkers to potential therapeutic targets?
Fernando José Magro Dias
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/82895/2007

Invariant Natural Killer T Cells in Allergic Asthma and Tolerogenic Therapy.
Luis Ricardo Silva Graca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82896/2007

Clinical approaches for ACS photosensitizers in gastroenterology application
Maria Filomena Rabaça Roque Botelho
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/82898/2007

Primary hyperparathyroidism: Clinical surveillance and genetic alterations
Ana Paula Soares Dias Ferreira
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/82899/2007

Induction of programmed cell death for the development of anti-fungal and anti-tumor therapies
Arnaldo António de Moura Silvestre Videira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/82906/2007

Alcoholic phenotypes and their children: genetic, neurocognitive and behavioural aspects
JOSE MARIA NEVES CARDOSO
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PIC/IC/82907/2007

Evaluation of interventions for preschool children presenting Attention-Deficit/Hyperactivity Disorder symptoms
Maria João Rama Seabra Santos
Faculdade de Psicologia e de Ciências da Educação da Universidade de Coimbra (FPCE/UC)

PIC/IC/82908/2007

Copy number variation in male infertility: an array CGH screening in the Portuguese population
Alexandra Manuel Ferreira Lopes
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/82914/2007

National Network of Centers for Clinical Research and Clinical Trials (PTCRIN)
Ana Cristina Brito Almeida Sampaio Cruz
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82915/2007

Oral health in renal transplant recipients receiving different immunosuppressive agents
Benedita Sampaio Maia
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PIC/IC/82917/2007

Pediatric Helicobacter pylori infection: a study model of gastrointestinal mucosal innate immune response
Ana Isabel Gouveia Costa da Fonseca Lopes
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PIC/IC/82920/2007

Cardiovascular risk and inflammation- contribution to the etiopathogenesis of atherosclerosis and cardiovascular disease
João Eurico Cortez Cabral da Fonseca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82921/2007

Epidemiology of ESBL producers in nursing homes
Helena Maria Neto Ferreira de Sousa
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PIC/IC/82922/2007

Candida bloodstream infections in oncological patients: molecular epidemiology, antifungal susceptibility and risk factors in a portuguese central hospital
Célia Sacramento Santos Pais
Universidade do Minho (UM)

PIC/IC/82924/2007

Effects of Exercise in the Prevention of Osteoporosis and Falls - Study in Premenopausal and Postmenopausal Women
Jorge Mota
Faculdade de Desporto da Universidade do Porto (FADE/UP)

PIC/IC/82931/2007

Complement system activation and erythrocyte complement-regulatory receptors in patients infected with Plasmodium falciparum.
Marcelo Sousa Silva
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PIC/IC/82932/2007

Psychomotor Therapy and Psychological Counselling to Manage Anxiety in Occupational Context
Rui Fernando Roque Martins
Faculdade de Motricidade Humana (FMH/ULisboa)

PIC/IC/82937/2007

Adjustment to divorce on parents and children on preschool age: Validation of a program to promote positive co-parenting
Bárbara Fernandes de Carvalho Figueiredo
Universidade do Minho (UM)

PIC/IC/82938/2007

EPIDEMIOLOGY OF DEMENTIA AND DEPRESSION IN THE ELDERLY: IMPLEMENTATION OF THE 10/66 RESEARCH PROTOCOL IN PORTUGAL
Fernando Miguel Teixeira Xavier
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/82940/2007

Oral Diseases in the Portuguese Geriatric Population
Sofia de Mello Lima Teixeira Santos Arantes e Oliveira
Faculdade de Medicina Dentária da Universidade de Lisboa (FMD/ULisboa)

PIC/IC/82942/2007

OSTEOBIOTICS- A novel therapy based on antibiotic local releasing for the treatment of osteomyelitis
Fernando Jorge Mendes Monteiro
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PIC/IC/82944/2007

Depression in young adulthood: vulnerability and pathology intervention
Anabela Maria Sousa Pereira
Universidade de Aveiro (UA)

PIC/IC/82946/2007

A new therapeutic approach for the wound-healing process in diabetic ulcerations - chitosan modified with silane wound dressings
Maria Ascensão F S Lopes
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PIC/IC/82947/2007

Etiology of osteoporosis: study of the causal relationships between elemental concentration profiles and mechanisms of bone formation and resorption.
José Américo Almeida de Brito
Fundação da Universidade de Lisboa (FUL/ULisboa)

PIC/IC/82955/2007

Predicting and preventing the adverse effects of intrahepathic cholestasis of pregnancy by determining bile acid profile and prescribing ursodeoxycholic acid
Dora Brites
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PIC/IC/82956/2007

Acção da insulina induzida pelo estado pós-prandial - da ciência básica aos estudos clínicos
Maria Paula Borges de Lemos Macedo
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/82957/2007

Food intake, hyperhomocysteinaemia and cardiovascular disease in type 2 diabetic patients
Maria Helena Rodrigues Gonçalves Soares Costa
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/82958/2007

Clinical and Genetic Study of the Agenesis of Maxillary Lateral Incisors
Elsa Logarinho
Universidade do Minho (UM)

PIC/IC/82962/2007

Evaluation of molecular defects in Myelodysplastic Syndromes and Secondary Acute Myeloblastic Leukemia patients - Implications in the prognostic and in the therapeutic approach
Ana Bela Sarmento Ribeiro
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/82963/2007

Tactile-kinaesthetic stimulation to the premature infant in a neonatal care unit: short, medium and long term effects in infants' and parents' health and well-being
Bárbara Fernandes de Carvalho Figueiredo
Universidade do Minho (UM)

PIC/IC/82964/2007

The Role of B-glucan in Pneumocystis jirovecii Pneumonia (PcP): from Diagnosis and Genetics to Drug Target.
Olga Maria Guerreiro de Matos
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PIC/IC/82965/2007

Stroke-induced changes on autonomic nervous system
Maria Isabel de Sousa Rocha
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82966/2007

Prevalence and progression of cardiovascular metabolic and atherosclerotic adverse drug reactions in HIV-Infected Patients Receiving “de novo” Highly Active Antiretroviral Therapy
Jorge Manuel Silva Junqueira Polonia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/82967/2007

Are genetic polymorphisms in inflammatory molecules risk factors for the development of autoimmune thyroiditis and associated cardiovascular and neoplasic diseases?
Ana Paula Soares Dias Ferreira
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/82968/2007

PTEN: a molecular determinant to HER-targeted therapies response rates in patients with breast cancer
Fernando Schmitt
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/82969/2007

Evaluating the therapeutic potential of VIP VPAC1 receptor antagonists to ameliorate the cognitive deficits in temporal lobe epilepsy.
Diana Lina Jerónimo da Cunha Reis
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82979/2007

Studying Chlamydia trachomatis chromosome rearrangements using clinical isolates: new antigenic combinations?
JOÃO PAULO DOS SANTOS GOMES
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/82985/2007

Genetic modifiers in the therapeutic response to hydroxyurea in Sickle Cell Disease
Ângela Inácio
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PIC/IC/82988/2007

Chronic Inflammatory Articular Diseases and Monocytes CD14lowCD16+ - Pathophisiology Implications and Therapeutic Potencial Applications
Jaime Branco
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/82989/2007

Advanced Clinical Analysis Tools for Bone Regenerative Treatments
Francisco Andrade Pires
Instituto de Engenharia Mecânica - Porto (IDMEC Porto/FE/UP)

PIC/IC/82990/2007

Environmental impact on the sperm quality of Portuguese men
João RamalhoSantos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PIC/IC/82991/2007

Immunological basis for the association of hypersomnic sleep disorders and cardiovascular disease
LUÍS FILIPE FERREIRA MOITA
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82995/2007

Evaluation of Concept Generalization Hability and Gestalt in People with Asperger Syndrome using Drawing Analysis and Eye Tracking
Carlos Manuel Nunes Filipe
CADIn - Centro de Apoio ao Desenvolvimento Infantil (CADIn)

PIC/IC/82996/2007

Implicit learning functions of the basal ganglia: A clinical and cognitive perspective
Marieke van Asselen
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/82997/2007

Identification of human genetic mutations affecting interaction between MEF2C and target genes during chondrocyte maturation (ChondroMEF)
Natércia Conceição
Centro de Ciências do Mar (CCMar)

PIC/IC/82998/2007

Predictive value of anxiety and depression on the course and mortality of heart failure
Graça Maria Pereira Cardoso
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/83000/2007

Characterisation of Chlamydia trachomatis infections in Portugal included those associated to proctitis (Lymphogranuloma venereum).
Filomena Martins Pereira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PIC/IC/83001/2007

NCLs: a model to study the role of lipids in neurodegenerative diseases
CARLA ANDREIA FIDALGO TEIXEIRA
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83002/2007

HLA association in five immune-mediated diseases
Hélder Spínola
Universidade da Madeira (UMA)

PIC/IC/83009/2007

Effects cardiac rehabilitation and exercise training programs on functional capacity, coronary risk factors, and endothelial dysfunction and inflammation markers in coronary artery disease patients
José Oliveira
Faculdade de Ciências do Desporto e de Educação Física (FCDEF/UP)

PIC/IC/83010/2007

The role of lipoproteins on the progression of hepatitis C viral infection and treatment response
Maria Fátima Soares Silveira Serejo Leal da Silva
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83012/2007

Clinical and immunological characterization of Giardia lamblia infection: application of Giardia-specific FABP proteins in immunodiagnostic and in control of therapy
Maria do Céu Rodrigues de Sousa
Universidade de Coimbra (UC)

PIC/IC/83017/2007

Cellular Kinetics and colorectal carcinogenesis: comparative study between right and left colon
PEDRO MANUEL NARRA DE FIGUEIREDO
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83018/2007

Mammography: Impact of digital imaging technologies and optimisation of its use in breast cancer screening and diagnosis
Ana Isabel Lourenço Pascoal
Faculdade de Engenharia da Universidade Católica Portuguesa (FE/UCP)

PIC/IC/83020/2007

Prevalence of Familial Hypercholesterolaemia and analysis of cardiovascular risk factors in the portuguese populution
Mafalda Bourbon
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83023/2007

Clinical implications of activation of PI3K/Akt signaling pathway in primary adult acute lymphoblastic leukemia
João Mascarenhas Forjaz de Lacerda
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83024/2007

Influence of an intervention program to identify and support cancer inpatients with emotional stress
Aida Maria de Oliveira Cruz Mendes
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PIC/IC/83027/2007

Dissecting genetic and behavioural determinants of obesity in Portuguese population aiming a management intervention
Teresa Maria Taylor da Silva Kay
Hospital de Dona Estefânia (HDE/CHLC)

PIC/IC/83028/2007

Community-acquired severe sepsis: early recognition and appropriate therapeutic will save lives
António Carlos Megre Eugénio Sarmento Megre Eugénio Sarmento
Hospital Geral de Santo António, SA (HGSA)

PIC/IC/83031/2007

Novel pathophysiological biomarkers in multiple sclerosis, glaucoma and genetic optic neuropathies: implications for early diagnosis, monitoring and understanding of disease progression
Miguel de Sá e Sousa de Castelo Branco
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83032/2007

Atherosclerosis in chronic inflammatory rheumatic diseases: T and NK cells as risk factors
Fernando Aguilar Arosa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/83033/2007

Portuguese Network of Drug Hepatotoxicity
Rui Manuel de Carvalho Marques dos Santos
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83035/2007

PROMPT RESPONSE TO (RE)EMERGING INFECTIONS AND BIO-PREPAREDNESS
Maria de Lurdes Paiva Monteiro
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83036/2007

Implementation of family psychoeducational interventions in the treatment of psychotic disorders
Maria de Fátima Pereira Batista Dias
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PIC/IC/83037/2007

Mapping of genes predisposing to familial thyroid tumours
Valdemar de Jesus Conde Máximo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/83040/2007

Pharmacological and toxicological characterization of new drugs combination for breast cancer therapy
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PIC/IC/83042/2007

Evaluating and monitoring the pattern of resistance of the antibiotics used for treatment and prophylaxis of meningococcal disease in Portugal from 2002 to 2010
Laura Maria Lourenço Brum da Cruz Martins
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83048/2007

Obesity, metabolic syndrome, and cardiovascular risk in premenopausal women: the effect of reduction in body fat mass
José António Silva-Nunes
Escola Superior de Tecnologia da Saúde de Lisboa (ESTeSL/IPL)

PIC/IC/83049/2007

Functional analysis of a newly identified CD27+CD28++ T-cell population and its role in autoimmune diseases
MARGARIDA LIMA
Hospital Geral de Santo António, SA (HGSA)

PIC/IC/83050/2007

Prevalence of psychopathology in Portuguese children and adolescents: a two-stage epidemiological study
Pedro Miguel Brito da Silva Dias
Centro Regional do Porto da Universidade Católica Portuguesa (CRP/UCP)

PIC/IC/83051/2007

Tumour Banks - In the Way of Translational Research
Lina Maria Rodrigues Carvalho
Hospitais da Universidade de Coimbra, E.P.E (HUC/UC)

PIC/IC/83052/2007

Regulation of gene expression and gemcitabine chemoresponse in non-small cell lung cancer
Lina Maria Rodrigues Carvalho
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83056/2007

Development and Impact of an Information System for Health Care Quality Assurance and Monitoring, on a Network of Primary Health Care Units with Electronic Medical Records
Paulo Jorge Morais Zamith Nicola
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PIC/IC/83057/2007

Evaluation of the factors of adherence to treatment in patients infected with the Human Imunodeficiency Acquired Virus (HIV)
Paulo Alexandre Soares Moreira
Fundação Minerva - Cultura - Ensino e Investigação Científica (FMinerva)

PIC/IC/83059/2007

CLINICAL RELEVANCE OF NEUROPHYSIOLOGY AND NEUROIMAGING MARKERS OF ABNORMAL BRAIN CONNECTIVITY IN SCHIZOPHRENIA: DIFFERENTIATION BETWEEN PATIENTS WITH THE FIRST EPISODE AND PATIENTS WITH CHRONIC SCHIZOPHRENIA
JOÃO EDUARDO MARQUES TEIXEIRA
Faculdade de Psicologia e de Ciências da Educação da Universidade do Porto (FPCE/UP)

PIC/IC/83062/2007

The differential effect of WT and V30M Transthyretin in the hepatic microenvironment and vasculature response.
Rui José Rodrigues Perdigoto
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83063/2007

CONTRIBUTION TO THE STUDY OF THE INFLUENCE OF LIFESTYLE IN CANCER DEVELOPMENT AND TREATMENT OUTCOMES: A STUDY CENTRED IN STOMACH AND COLERECTAL CANCER
Jorge Manuel Nunes dos Santos
Hospital Geral de Santo António, SA (HGSA)

PIC/IC/83064/2007

Chlamydia trachomatis and Genital Mycoplasma infections in pregnant women and in the neonate
Rita Maria Rodrigues Teixeira de Castro
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PIC/IC/83065/2007

Implications for therapy and disease presentation of the changes triggered by the use of the pneumococcal 7-valent conjugate vaccine
Mário Nuno Ramos de Almeida Ramirez
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83067/2007

Screening of urological cancers using novel epigenetic biomarkers
Carmen Jerónimo
Instituto Português de Oncologia de Francisco Gentil, Centro Regional de Oncologia do Porto (IPO Porto)

PIC/IC/83068/2007

Long-term impact of thymectomy performed in early infancy
Rui Manuel Martins Victorino
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83073/2007

PCR e RT PCR no diagnóstico da malaria importada e no seguimento do tratamento antimalárico.
Antonio Manuel Oliveira Castro
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PIC/IC/83074/2007

Transcriptional variation of the ATXN3 gene as modulator of the clinical heterogeneity in Machado-Joseph disease (MJD).
Maria Manuela de Medeiros Lima
Universidade dos Açores (UAçores)

PIC/IC/83075/2007

Acetylator status characterization and therapy individualization of tuberculosis patients
Henriqueta Alexandra Mendes Brêda Lobo Coimbra Silva
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83076/2007

DIAGNOSTIC VALUE OF FLOW CYTOMETRIC EVALUATION OF ERITHROID IMMUNOPHENOTIPIC ABNORMALITIES IN PERIPHERAL BLOOD OF PATIENTS WITH MYELODISPLASTIC SYNDROMES
Ana Maria Lopez de Macedo
Universidade da Beira Interior (UBI)

PIC/IC/83077/2007

Role of autonomic nervous system in paroxysmal atrial fibrillation
Filipe Silva Carvalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83082/2007

Genetics and Biochemical determinants of oxidative stress in Multiple Sclerosis patients
Ana Alexandra Duarte Martins da Silva
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/83083/2007

Disorders of nuclear-mitochondrial intergenomic communication: yet another challenge for clinicians
Laura Ferreira Teixeira Vilarinho
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83084/2007

DEVELOPMENT AND VALIDATION OF VASO-OCCLUSION EARLY PREDICTORS IN A MENDELIAN MODEL OF VASCULAR DISEASE
João Lavinha
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83085/2007

Group B streptococcal (GBS) neonatal infection, colonization and infection of pregnant women: association of serotypes with clinical syndromes, mechanisms of antimicrobial resistance and clonal types.
Filomena Martins Pereira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PIC/IC/83086/2007

Introduction of RFID identification in the blood collection, storage and transfusion chain
ANTÓNIO MIGUEL PONTES PIMENTA MONTEIRO
Instituto Português do Sangue e Transplantação IP (IPS)

PIC/IC/83087/2007

Clinical and radiological characterisation of DISH/Chondrocalcinosis families
Jacome Bruges Armas
Hospital Santo Espírito de Angra do Heroísmo (HSEAH)

PIC/IC/83088/2007

Adipose tissue as endocrine organ: effects and actions in obesity
Luisa Maria Carvalho Veiga
Escola Superior de Tecnologia da Saúde de Lisboa (ESTeSL/IPL)

PIC/IC/83089/2007

Etiology of the lower respiratory infections in children under the age of two
Maria Teresa Possante Marques
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/83093/2007

BIOMESH - Study of synthetic and xenograft meshes implications in reconstructive surgery of female pelvic floor dysfunctions using animal models
Teresa Mascarenhas
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83095/2007

Sensitivity of Influenza A viruses to oseltamivir and amantadine by fluorescence assay and pyrosequencing: a study performed on viruses circulating in the community and in specific risk groups
Helena Rebelo-de-Andrade
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83097/2007

Effects of Bariatric Surgery on Clinical Co-Morbidities, Athero-Thrombogenic/Inflammatory Biomarkers and Gastrointestinal Peptides in High Cardiovascular Risk Massive Obese Patients with and without the Metabolic Syndrome: A Prospective Follow-up Study
Pedro Orlando Rodrigues
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/83098/2007

From human genomics to animal modeling of rheumatic diseases
Ana Sofia Simões Domingues de Almeida Oliveira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83099/2007

Genetic, epidemiologic and clinical contribution towards the understanding of mental retardation
Paula Maria Vieira Jorge
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83100/2007

Inteligente ECG Diagnostic
Rui Silva
Fundação Minerva - Cultura - Ensino e Investigação Científica (FMinerva)

PIC/IC/83102/2007

Cognition in Hyperactive Adults, their Relatives, and related disorders: an fMRI study - CHARM
Fernando Miguel Teixeira Xavier
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/83103/2007

Diagnosis, Prognosis and Treatment of Cystic Fibrosis
Margarida Sofia Pereira Duarte Amaral
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PIC/IC/83104/2007

Investigation of potential targets to inhibit the progression of HPV-induced cervical carcinoma
Adhemar Longatto
Universidade do Minho (UM)

PIC/IC/83107/2007

Tobacco Smoke and Risk for Chronic Obstructive Pulmonary Disease and Lung Cancer: Towards Early Diagnosis and Preventive Interventions
Deborah Penque
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83111/2007

Detection of serogroups and virulence genes of Vero cytotoxin-producing Escherichia coli (VTEC) in E. coli isolated from food, from cattle and human stools and from water samples
José Manuel Alves Correia da Costa
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83115/2007

Value of flow cytometry in the diagnosis and biological study, and evolution of membrane erythrocyte disorders
Alice Santos-Silva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/83116/2007

THREE-DIMENSIONAL ULTRASOUND IMAGING SEGMENTATION METHODS
Jaime Batista dos Santos
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PIC/IC/83117/2007

Study of the potential allergenicity of genetically modified food
Rita Batista
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83118/2007

Neuronal Ceroid-Lipofuscinosis: Genotype-phenotype analysis in old and new disease variants
Maria Gil Roseira Ribeiro
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83120/2007

Outcome after severe trauma: Implications for the clinical approach
Altamiro Manuel Rodrigues Costa Pereira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83121/2007

A new clinical approach and the novel concept for bioresorbable screw in orthopaedic surgery
José Carlos Pereira Pinto Noronha
Universidade de Aveiro (UA)

PIC/IC/83123/2007

Intra-prostatic botulinum toxin injection for the treatment of Benign Prostate hyperplasia (BPH)
Paulo Dinis dos Santos de Oliveira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83124/2007

Atherogenicity in obese children and adolescents. Premature definition of atherogenic risk and its progression with age and lifestyle
LUÍS FILIPE BARBOSA AMADO BELO
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/83125/2007

Molecular characterization of normal endometrium and simple hyperplasia in risk gynecological profiles to the development of endometrioid carcinoma.
Carlos Manuel Domingues Freire de Oliveira
Hospitais da Universidade de Coimbra, E.P.E (HUC/UC)

PIC/IC/83126/2007

New approaches for inactivation, treatment and immunoprophylaxy of cryptosporidiosis
José Manuel Alves Correia da Costa
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PIC/IC/83128/2007

Vulnerability to Stress: From Genetics to Psychometrics
Adriano Supardo Vaz Serra
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83129/2007

Surveillance, Control and Prevention of Nosocomial Outbreaks in Portugal.
Jorge Cândido Pinheiro da Costa Machado
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83130/2007

Small dense lipoproteins in dyslipidemia - Genetic and metabolic correlation
José Carlos Azevedo Oliveira
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/83131/2007

MAXBONE - New Routes towards Maxillofacial Reconstruction: from Stem Cells to Clinical Application
Rui L Reis
Universidade do Minho (UM)

PIC/IC/83132/2007

ANEURYSM - Investigation of blood flows in cerebral aneurysms
Mónica Sofia Neves de Freitas Oliveira
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PIC/IC/83134/2007

Studies on the diversity of Acinetobacter spp using phenotypic and genotypic tools
Paula Cristina Maia Teixeira
Escola Superior de Biotecnologia (ESB/UCP)

PIC/IC/83136/2007

BEFORE YOU GET BURNT: Peer Education in an academic context
António de Jesus Couto
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PIC/IC/83137/2007

Autonomic nervous system and cardiovascular control. Study in humans and in a rat model of vira targetting in paraventricular nucleus
Filipe Silva Carvalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83138/2007

Integrated Interventions For Severe Mental Ill People In The Community
Joaquim Filipe Candeias de Sousa Gago
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/83139/2007

Early laboratorial diagnosis of drug-resistant TB: new molecular insights into the emergency of M/XDRTB strains in Lisbon.
Isabel Couto
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PIC/IC/83142/2007

Maternal Overweight and Obesity versus Breastfeeding Success
Juliana Almeida de Souza
Instituto Politécnico de Bragança (IPBragança)

PIC/IC/83144/2007

Development of nutritive and non-nutritive sucking patterns in premature babies. Analysis of the temporal structure and pressure of sucking
Manuel de Sousa e Cunha
Hospital Professor Dr. Fernando da Fonseca (HPFF)

PIC/IC/83145/2007

Clinical and molecular pathology in Duchenne Muscular Dystrophy patients: towards personalised cutting-edge therapy
Elsa Maria Ribeiro Bronze da Rocha
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83146/2007

NEURODEVELOPMENTAL AND BEHAVIOUR OUTCOME OF CHILDREN BORN VERY-LOW-BIRTH-WEIGHT COMPARED WITH THEIR PEERS AT SCHOOL AGE
Manuel de Sousa e Cunha
Hospital Professor Dr. Fernando da Fonseca (HPFF)

PIC/IC/83147/2007

Impact of diet and drug therapy in a population of overweight patients with acute coronary syndromes
Pedro Monteiro
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83149/2007

Ankylosing Spondylitis: epidemiological economical and genomical characterization. The repercussion in clinical practice.
Jaime Branco
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/83151/2007

Identification of new antifungal targets to control human fungal recurrent infections
ANA PAULA FERNANDES MONTEIRO SAMPAIO CARVALHO
Universidade do Minho (UM)

PIC/IC/83152/2007

Emotional management of stroke´s patient and caregiverers: A longitudinal and transversal study
carlos Manuel Lopes Pires
Universidade de Coimbra (UC)

PIC/IC/83153/2007

MUC1 mucin polymorphism- a new susceptibility and prognostic marker in lung cancer
Luis Filipe Santos Silva
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/83156/2007

Parasuicide, adolescence and families. An intervention in the area of mental health
José Carlos Pereira dos Santos
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PIC/IC/83157/2007

Clinical Guidelines to Care People with Dementia
MANUEL JOSÉ LOPES
Universidade de Évora (UE)

PIC/IC/83158/2007

SPIYChiLD - Spirometry Playground and Interpretation model for Young Children's Lung Disorder assessment
jOSE aNTONIO rEIS cOSTA TRINDADE
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PIC/IC/83162/2007

HPV, Cancro do Colo do Útero e Cancro da Cabeça e Pescoço: Combinação de MALDI Imagem, 2D-PAGE, HPLC-ESI-MS e RMN como nova abordagem para a identificação inequívoca de biomarcadores
José-Luis Capelo-Martinez
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PIC/IC/83163/2007

Comparative transcriptomics in human spermatozoa: identification of novel male (in)fertility genes
Carlos Eugenio Plancha dos Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83164/2007

Ultrasonic evaluator of cardiac implants: velocimetry and elastography (AULIC)
Maria da Graça Cristo dos Santos Lopes Ruano
Universidade do Algarve (UAlg)

PIC/IC/83170/2007

Epidemiology of human cytomegalovirus infection in young children and their families
José António Martinez Souto de Oliveira
Centro Hospitalar Cova da Beira (CHCB)

PIC/IC/83171/2007

Determinants of insomnia in portuguese adolescents. Repercussions in local health care planning
Carlos Manuel de Figueiredo Pereira
Escola Superior de Saúde de Viseu (ESSV/IPV)

PIC/IC/83172/2007

Development of markers with implications on the laboratory diagnosis of antibiotic resistance of Mycobacterium tuberculosis and the therapeutics of tuberculosis
Susana David
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/83174/2007

Genetic linkage of resistance and virulence determinants in uropathogenic Klebsiella pneumoniae and Escherichia coli isolated from hospital and community-acquired urinary tract infections
Aida Duarte
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PIC/IC/83175/2007

Metabolic impact of advanced heart failure and cachexia
Pedro Monteiro
Centro de Neurociências e Biologia Celular (CNBC/UC)

PIC/IC/83176/2007

Integrated DNA and Expression Array Studies Tailored to Identify Clinically Relevant Molecular Targets in Primary Brain Tumors.
Maria Lúcia Primo Nobre de Oliveira Roque
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83177/2007

Noninvasive measurement of hepatic triglyceride and visceral adiposity as early markers of type 2 diabetes in obese subjects
Filipe Caseiro Alves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PIC/IC/83182/2007

Study of Wilson Disease in Portugal: contribution to new diagnostic tools and novel therapeutic targets
LUCIANA MARIA GONÇALVES DA COSTA
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83184/2007

Aqueous spot fluorometry as an indicator for the role of intraocular inflammation in the progression of diabetic macular edema.
MARIA DA CONCEIÇÃO LOPES LOBO DA FONSECA
Associação para a Investigação Biomédica e Inovação em Luz e Imagem (AIBILI)

PIC/IC/83187/2007

PROGNOSTIC IMPACT OF MOLECULAR CHARACTERIZATION OF PRIMARY TUMOR, CIRCULATING TUMOR CELLS AND LIVER METATASES IN PATIENTS WITH COLORECTAL CANCER SUBMITED TO A SURGICAL TREATMENT.
José Guilherme Lopes Rodrigues Tralhão
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83189/2007

Increased bacteriological security and extension of shelflife of platelets products for transfusion.
Maria Salomé de Melo Maia Gonçalves
Instituto Português do Sangue e Transplantação IP (IPS)

PIC/IC/83191/2007

Role of the oral microbiota in the emergence and evolution of denture-related stomatitis
Célia Sacramento Santos Pais
Universidade do Minho (UM)

PIC/IC/83192/2007

Identification and Validation of Biomarkers for Glioblastoma Prognosis and Therapeutic Response Prediction
RUI MANUEL VIEIRA REIS
Universidade do Minho (UM)

PIC/IC/83193/2007

Regulation of ZAP-70 and PTEN activity and stability in chronic lymphocytic leukemia: prognostic and therapeutic implications
João Pedro Taborda Barata
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83195/2007

Reading assessment: design and validation of a test for children from 1st to 4th grade
Arlette Thérèse Marcelle Marie Joseph Verhaeghe
CADIn - Centro de Apoio ao Desenvolvimento Infantil (CADIn)

PIC/IC/83196/2007

Clinical relevance of assymptomatic colonization by beta-hemolytic Streptococcus
Ilda Maria Barros Santos Gomes Sanches
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PIC/IC/83197/2007

Evaluation of results and impact in drug prevention programmes
Telmo Ventura Mourinho Baptista
Faculdade de Psicologia e de Ciências da Educação da Universidade de Lisboa (FPCE/UL)

PIC/IC/83198/2007

Clinical relevance of Pharmacogenetics in Inflammatory Bowel Disease
Maria João Prata
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/83202/2007

DigiScope - DIGItally enhanced stethoSCOPE for clinical usage
Miguel Coimbra
Instituto de Telecomunicações (IT)

PIC/IC/83205/2007

Assessment of biochemical markers of bone turnover in normal and abnormal fracture healing and in osteoporosis. Novel cells-materials construct based approaches to fracture healing.
Maria Isabel Ribeiro Dias
Universidade do Minho (UM)

PIC/IC/83209/2007

Kidney lesion and dysfunction in obese children
Alberto António Moreira Caldas Afonso
Hospital de São João EPE (HSJ)

PIC/IC/83210/2007

Invasive candidosis: validation of new diagnostic, preventive and therapeutic concepts
Acácio Gonçalves Rodrigues
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83211/2007

Formulation of targeted functional micro/nanoparticles for cancer therapy
Maria Margarida Canas Mendes de Almeida Cardoso
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PIC/IC/83212/2007

Frequency of HFE mutations in hemophilia: possible influence on factor VIII plasma levels
Eugénia Ermelinda Martins da Cruz
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/83213/2007

Investigating the putative role of HPV microRNAs or siRNAs in the molecular transformation and pathogenesis of
Adhemar Longatto
Universidade do Minho (UM)

PIC/IC/83214/2007

Does malaria increase susceptibility to tuberculosis? The role of malaria-pigment induced immune-suppression.
Thomas Hänscheid
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83215/2007

Detection, typing and viability studies of emergent agents of nosocomial infections
Cidalia Pina Vaz
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83216/2007

Differential toxicogenomic responses involved in hepatic cholestasis and steatosis: molecular mechanisms of bile acids therapy
Carlos Palmeira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PIC/IC/83217/2007

Chlamydia trachomatis infection in adolescents: the “hidden epidemic”?
Maria José Borrego
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83219/2007

Quick Methods for Detection of Resistances in Candida non albicans
Domingas do Rosario Verissimo Jacinto Tavares de Oliveira
Universidade do Minho (UM)

PIC/IC/83220/2007

The role of cold weather on the incidence of acute coronary syndrome
Paula Santana
Universidade de Coimbra (UC)

PIC/IC/83225/2007

Neuro-computed assisted HIFU oncologic treatment system (NAHOTS)
Maria da Graça Cristo dos Santos Lopes Ruano
Universidade do Algarve (UAlg)

PIC/IC/83228/2007

Breast Cancer Diagnosis - A new PET Scanner developped in Portugal
Miguel de Sá e Sousa de Castelo Branco
Universidade de Coimbra (UC)

PIC/IC/83230/2007

Delirium in post-surgical elderly patients: diagnosis, prevention, outcome and search for biomarkers
Horácio António Jesus Firmino
Hospitais da Universidade de Coimbra, E.P.E (HUC/UC)

PIC/IC/83237/2007

New Dimensions in Cervical Cancer Screening and in Clinical Practice: Cytology, HPV Genotyping, messenger RNA Transcription, Viral Load, and DNA Integration
Angela Maria Chambel Pista
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83240/2007

ICADD - Imagiology Computer Aided Detection and Diagnosis
Victor Alves
Universidade do Minho (UM)

PIC/IC/83242/2007

LASER - Evaluation of Er:YAG laser efficacy in soft and hard tissue impaired healing
Maria Helena Raposo Fernandes
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PIC/IC/83243/2007

Autonomic nervous system in recurrent renal stone disease
Maria Isabel de Sousa Rocha
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83245/2007

Study and characterization of dermatophytes: a contribution for the organization of a national mycological collection
Maria Laura Martins Rosado de Sousa
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83247/2007

Molecular Caracterization and Gene Expression of DNA Repair Genes and HER Family in Bronchial Aspirates
Carlos Manuel da Silva Robalo Cordeiro
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83248/2007

Health Promotion and Integrated Cardiovascular Disease Prevention - CINDI before 20 (Sub-20) (Healthy children in healthy families)
Fernando Manuel Archer Moreira Paraíso de Pádua
Instituto Nacional de Cardiologia Preventiva (INCP)

PIC/IC/83250/2007

CLINSKIN - Clinical relevance of a new strategy to (re)construct epidermal, dermal and skin analogues for severe skin lesions.
Alexandra P Marques
Universidade do Minho (UM)

PIC/IC/83251/2007

Contribution of blaCTX-M genes from Enterobacteriaceae isolates to the spread of multidrugresistance in hospiatal and community environments
Manuela Caniça
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83252/2007

Molecular analysis of the Mucolipidosis II and III in Portugal: characterization of the mutational spectrum and relationship with clinical phenotypes
Sandra Catarina da Conceição Alves
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83254/2007

Pharmacogenomic profile of prediction response to radiotherapeutic treatment in breast cancer
RUI Manuel de MEDEIROS Melo Silva MEDEIROS
Instituto Português de Oncologia de Francisco Gentil, Centro Regional de Oncologia do Porto (IPO Porto)

PIC/IC/83255/2007

The effects of exercise on mitochondrial function isolated from in vitro ischemic-reperfused rat hearts
José Magalhães
Faculdade de Desporto da Universidade do Porto (FADE/UP)

PIC/IC/83257/2007

NEEDS FOR CARE ASSESSMENT IN MENTALLY DISORDERD INMATES
Fernando Miguel Teixeira Xavier
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/83258/2007

Human immunodeficiency virus type 2: subtypes (groups) and patterns of resistance in the central region of Portugal
António Abel Garcia Meliço-Silvestre
Hospitais da Universidade de Coimbra, E.P.E (HUC/UC)

PIC/IC/83260/2007

Precursors of atherosclerosis in a high risk pediatric population
SILVIA ALVARES
Hospital Geral de Santo António, SA (HGSA)

PIC/IC/83265/2007

Plasmid-borne fluoroquinolone resistance in clinical Enterobacteriaceae isolates and potential risks of its dissemination in hospital and community environments
Manuela Caniça
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PIC/IC/83266/2007

Expression Analysis of Mitotic Checkpoint Genes and Prognostic Significance in Brain Cancer
Hassan Bousbaa
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PIC/IC/83267/2007

Genetic modulation of the response to morphine administration: pharmacogenomic profiling in cancer pain patients
RUI Manuel de MEDEIROS Melo Silva MEDEIROS
Instituto Português de Oncologia de Francisco Gentil, Centro Regional de Oncologia do Porto (IPO Porto)

PIC/IC/83269/2007

Natural transformation in aquisition and dynamic of integrons of multidrug resistant Acinetobacter spp.
Gabriela Conceição Duarte Jorge da Silva
Universidade de Coimbra (UC)

PIC/IC/83274/2007

Definition of Asperger Syndrome subtypes
Nuno Lobo Antunes
CADIn - Centro de Apoio ao Desenvolvimento Infantil (CADIn)

PIC/IC/83275/2007

Impact of diet and lifestyle intervention for diabetes in the clinical and biochemical profile and outcome in a population of acute coronary syndrome patients
Pedro Monteiro
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83276/2007

Gene expression of Candida albicans and Aspergillus fumigatus clinical isolates by microarrays following antifungal therapy in vivo
Cidalia Pina Vaz
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83278/2007

Nursing contributions and challenges to the promotion of self-care in the elderly: the case of motor activity in the elderly with CVA
José Manuel de Matos Pinto
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PIC/IC/83280/2007

Continuous home health care: needs and strategies
António de Jesus Couto
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PIC/IC/83283/2007

Oral cavity cancer - Tumoral microenvironment study and new therapeutic targets
Marília de Assunção Rodrigues Ferreira Dourado
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PIC/IC/83286/2007

Reassessment of the clinical spectrum of mood disorders: neurocognitve and neuroimaging correlations
João Miguel Seiça Bessa Peixoto
Universidade do Minho (UM)

PIC/IC/83287/2007

Prompt Patient Height and Weight (PPHW)
João José Lopes Gomes
Hospital Geral de Santo António, SA (HGSA)

PIC/IC/83289/2007

Diagnosis and Clinical Profile of Infections caused by Rickettsia slovaca and Rickettsia akari in Portuguese Children
Rita De Sousa
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83293/2007

The role of exercise on mitochondrial function from diabetic rats: Biochemical, functional and histological evidence in skeletal muscle, heart and liver mitochondria
António Alexandre Moreira Ribeiro de Ascensão
Faculdade de Desporto da Universidade do Porto (FADE/UP)

PIC/IC/83294/2007

Study and caracterization of the prevalence of feline and canine hyperthyroidism and its correlation with human hyperthyroidism in Portugal
Ana Isabel Calado Lopes
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/83298/2007

Preventive oral rehabilitation using new biomaterials
Mario Ramalho de Vasconcelos
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PIC/IC/83299/2007

Impact of apoptosis regulatory genes in the clinical responses of myelodysplastic patients to hypomethylating agents
Sérgio Dias
Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE (IPO Lisboa)

PIC/IC/83301/2007

Characterization and comparison of the multidrug-resistant enterococcal populations circulating in several Portuguese hospitals.
Rosario Mato Labajos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PIC/IC/83306/2007

Cognitive and Sensorial Stimulation Effects on Cognition, Functionality, Well-being and Quality of life of Alzheimer´s patients
José Aníbal Ribeiro da Fonte
Fundação Ensino e Cultura Fernando Pessoa (FECFP)

PIC/IC/83307/2007

Ambicios - Ambient Intelligence in Hospital Infection Control
José Maia Neves
Universidade do Minho (UM)

PIC/IC/83311/2007

The importance of endothelial progenitors and endothelial cells in vascular problems/complications of Age related Macular Degeneration and diabetic retinopathy
Sérgio Dias
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83315/2007

Sleep@home
José Luís Malaquias Ferreira Lima
ISA - Instrumentação e Sistemas de Automação (ISA)

PIC/IC/83316/2007

Development of Human IgG Monoclonal Antibodies. Potential use as immunotherapy in hemato-oncologic diseases.
SUSANA MAGADAN MOMPO
Instituto Superior de Saúde do Alto Ave (ISAVE)

PIC/IC/83317/2007

New Instrumentation for the Early Detection and Remote Monitoring of Cardiovascular Condition
João Manuel Peixoto Maldonado
Instituto de Investigação e Formação Cardiovascular (IIFC)

PIC/IC/83318/2007

Endothelial dysfunction, left ventricle dysfunction and cardiovascular risk factors in a paediatric population with coarctation of the aorta corrected in the neonatal period: a prospective study
José Carlos Neves da Cunha Areias
Hospital de São João EPE (HSJ)

PIC/IC/83322/2007

Quality Indicators of SNS Units.
Carles Iglesias Garcías
Novexem PORTUGAL, Lda (Novexem)

PIC/IC/83325/2007

Immunogenetic Determinants (HLA and non-HLA) of Susceptibility and Severity in Psoriatic Patients
Maria Manuela Selores Azevedo Gomes Meirinhos
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/83330/2007

Perinatal health care and early mother-child interaction
Isabel Loureiro
Escola Nacional de Saúde Pública (ENSP/UNL)

PIC/IC/83332/2007

The different presentations of Streptococcus pyogenes infections and the shifting patterns of antibiotic resistance
Jose Melo Cristino
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83333/2007

Clinical and molecular study of familial lipoprotein disorders with increase cardiovascular risk
Mafalda Bourbon
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PIC/IC/83335/2007

GENETIC SUSCEPTIBILITY TO METASTATIC BREAST CANCER
Jorge Francisco Dias Rodrigues Gaspar
Universidade Nova de Lisboa (UNL)

PIC/IC/83336/2007

Look4MyHealth
João Manuel Peixoto Maldonado
Instituto de Investigação e Formação Cardiovascular (IIFC)

PIC/IC/83340/2007

Characterization of products with antimicrobial activity in a black slug - Arion ater - used as anti-infectious traditional medicine
Luisa Maria Sobreira Vieira Peixe
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PIC/IC/83344/2007

Systemic lesions induced by chronic exposure to noise and vibration
MARIA JOÃO FEYTOR PINTO RODRIGUES DE OLIVEIRA DE MEIRELES MOREIRA
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/83345/2007

Towards In Utero Surgical Repair of Myelomeningocele: characterization of cytopathology and timing of the spina bifida lesion in a mutant mouse model of the disease.
Joaquim Luís Ramos Torres Couto Reis
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/83352/2007

Ventricular and endothelial dysfunction in a pediatric obese population with arterial hypertension
José Carlos Neves da Cunha Areias
Hospital de São João EPE (HSJ)

PIC/IC/83353/2007

Effects of n-3 DHA and EPA Essential Fatty Acids on the Clinical Outcomes and Atherosclerotic Plaque Instability/ Thrombogenic Bio-Markers in Patients with Acute Coronary Syndrome
Pedro Orlando Rodrigues
Faculdade de Ciências Médicas (FCM/UNL)

PIC/IC/83354/2007

Effects of aerobic and strength exercise therapies on physical condition, muscle strength and quality of life among Type II diabetes mellitus patients
Armando Manuel Mendonça Raimundo
Universidade de Évora (UE)

PIC/IC/83362/2007

Improving Acute Myeloid Leukemia therapy with drugs targeting topoisomerase II and prevention of secondary malignancy
João António Augusto Ferreira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/83363/2007

Septic and Hemorrhagic Shock - study of pathophysiology mechanisms, diagnosis e and therapeutic approach in a rat model.
MARIA MANUELA GRAVE RODEIA ESPADA NIZA
Faculdade de Medicina Veterinária (FMV/ULisboa)

PIC/IC/83364/2007

Changing patterns of Streptococcus agalactiae infections
Jose Melo Cristino
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PIC/IC/82716/2007

Early detection of cancer using serum biomarkers based on aberrant post-translational modifications of O-glycoproteins, O-PTM-Biomarkers.
Celso Albuquerque Reis
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/82773/2007

Risk Assessment in Acute Heart Failure - RAAHF
Paulo Bettencourt
Hospital de São João EPE (HSJ)

PIC/IC/82785/2007

MODIFIERS OF EXPRESSION OF HEMOCHROMATOSIS: looking for new markers of disease prognosis
Maria da Graça Beça Gonçalves Porto
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/82794/2007

Molecular diagnosis of OTC deficiency: too many unsolved cases
Luísa Cristina da Costa Azevedo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/82802/2007

Crohn's disease and mycobacterial infection
Amélia Maria Marques da Silva Rodrigues Sarmento Assunção
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/82824/2007

Therapies in familial amyloidotic polyneuropathy
Maria João Gameiro de Mascarenhas Saraiva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/82858/2007

Trends in incidence and outcome of Neurological Attacks: the second population-based study in Northern Portugal
Manuel Jorge Maia Pereira Correia
Centro Hospitalar Universitário do Porto (CHP/MS)

PIC/IC/82897/2007

Implicações clínicas dos factores genéticos envolvidos em doenças neurodegenerativas caracterizadas por alterações do movimento ou cognitivas
Isabel Alexandra Azevedo Silveira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/82923/2007

Exploring the role of E-Cadherin-HER interaction in the search of molecular biomarkers for the clinical management of gastric cancer patients
Raquel Seruca
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/82943/2007

Determinants of left ventricular hypertrophy before and after surgical treatment of aortic stenosis: clinical, morphofunctional, genetic and molecular correlations
Joaquim Adelino Correia Ferreira Leite Moreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/82986/2007

Vision and action processing in neurodevelopmental disorders: from disease mechanisms to new interventional strategies
Miguel de Sá e Sousa de Castelo Branco
Universidade de Coimbra (UC)

PIC/IC/83006/2007

Determinants of the decline in coronary heart disease (CHD) mortality in Portugal, 1987-2000
Ana Azevedo
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83013/2007

Clinical and Genetic study of X-linked mental retardation (XLMR) in Portugal: validation of a gene panel for diagnosis
Patrícia Espinheira de Sá Maciel
Universidade do Minho (UM)

PIC/IC/83026/2007

Idiopathic mental retardation: evaluation of a CGH microarray strategy for genetic diagnosis
Patrícia Espinheira de Sá Maciel
Universidade do Minho (UM)

PIC/IC/83029/2007

Increased cardiovascular risk in chronic renal insufficiency. Role of the novel monoamine-oxidase renalase in the sympathetic and renal dopaminergic activities
Manuel Pestana
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83038/2007

Cardiovascular risks factors for mothers and children 3 years after delivery
Ana Azevedo
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83108/2007

Whole human genome analysis of genetic imbalances and numerical abnormalities by single-nucleotide polymorphism (SNP)-arrays in gliomas: correlation with clinical and biological features of the disease.
Catarina Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PIC/IC/83122/2007

Study of Helicobacter pylori primary and secondary resistance to antimicrobial agents
JOSÉ MANUEL GODINHO MATOS ROMÃOZINHO
Universidade de Coimbra (UC)

PIC/IC/83154/2007

Cancer risk and irradiation: an epidemiological and genetic study of a cohort irradiated for Tinea capitis
José Manuel Lopes Teixeira Gomes
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/83155/2007

Mechanisms of neurosensorial inhibition associated with the cognitive deficits in Neurofibromatosis type 1: psychophysics, neurophysiology and functional and structural neuroimaging
Eduardo José Gil Duarte Silva
Universidade de Coimbra (UC)

PIC/IC/83159/2007

Prospective multicentric study on postoperative pain in Portugal
José Manuel Pereira Dias de Castro Lopes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83204/2007

Oxidative stress and genetic markers of cardiovascular risk in hypertension
Patricio Soares-da-Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83206/2007

Early Diagnosis of Alzheimer´s Disease: evaluation of recent classification criteria and proposal of new diagnostic tools
Maria Isabel Jacinto Santana
Hospitais da Universidade de Coimbra, E.P.E (HUC/UC)

PIC/IC/83221/2007

Risk for cardiovascular events in chronic kidney disease patients under haemodialysis. Lipid profile, anemia, vascular access and inflammation.
Alice Santos-Silva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/83226/2007

PURINERGIC AND CHOLINERGIC CONTROL OF LUNG-RESIDENT INFLAMMATORY CELLS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASES
Carlos Manuel da Silva Robalo Cordeiro
Universidade de Coimbra (UC)

PIC/IC/83231/2007

New approaches in multiple sclerosis diagnosis: the role of the choroid plexus.
JOÃO JOSÉ FERNANDES CARDOSO DE ARAÚJO CERQUEIRA
Universidade do Minho (UM)

PIC/IC/83232/2007

Mutational spectrum and improvement in laboratory techniques applied to molecular diagnosis of neurological disorders
Isabel Alonso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PIC/IC/83264/2007

Vitamin D, a candidate for new therapy of basal-like breast carcinomas
Fernando Schmitt
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PIC/IC/83290/2007

Cognitive Training in Brain Disorders: Effectiveness of cognitive stimulation and development of a new tool for Portuguese clinicians.
Adriana da Conceição Soares Sampaio
Universidade do Minho (UM)

PIC/IC/83297/2007

The relevance of HHV-6B in patients with Mesial Temporal Lobe Epilepsy (MTLE) due to Hippocampal Sclerosis (HS): implications in prevention and treatment
Maria Berta Silva
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PIC/IC/83312/2007

The PIRO Sepsis concept - implementation and validation of a new classification in Sepsis
Cristina GRANJA
Faculdade de Medicina da Universidade do Porto (FM/UP)

PIC/IC/83313/2007

RECONSTITUTION AND HOMEOSTHASIS OF THE IMMUNE SYSTEM FOLLOWING HIV-INFECTION
António Gil Pereira de Castro
Universidade do Minho (UM)