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R&D Projects

Call for Funding of Research and Development Projects in all Scientific Domains - 2008

Painel de Avaliação de Ciências da Saúde - 2008

Coordination

Fernando Lopes da Silva
University of Amsterdam, Netherlands

Evaluation

Ad Geurts van Kessel
Alice Warley
Anton J. G. Horrevoets
David Chambers
Fernando Giraldez Orgaz
Fernando Lopes da Silva
Francisco Bolumar
University of Alcala, Spain
George Griffin
Jean-Michel Bouler
Richard K Grencis
Roland Pochet
Sergio Cerutti
Trevor W Stone

Projects assigned

PTDC/SAU-BEB/098125/2008

Portable nano/micro-biosensor platform for ultrasensitive multidetection in blood samples - BloodFET
Elvira Maria Correia Fortunato
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FCTUNL/UNL)

PTDC/SAU-BEB/098245/2008

Experimental and mathematical investigation of the nanostructural properties of osteoporotic bone and its influence on the increased fracture risk in osteoporosis
Saba Abdulghani
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BEB/098405/2008

Nanoassemblies: Polymeric nanostructures for controlled drug delivery
Ana Margarida Moutinho Grenha
Universidade do Algarve (UAlg)

PTDC/SAU-BEB/098475/2008

Development of non-viral vectors for ocular gene therapy
Gabriela Araújo da Silva
Universidade do Algarve (UAlg)

PTDC/SAU-BEB/098477/2008

NovaSkin - A new tissue engineered skin substitute for the treatment of deep partial and full-thickness burn wounds
Jorge Alexandre Monteiro de Carvalho e Silva
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-BEB/098484/2008

Nanotechnology approaches for the treatment of methicilin-resistant staphylococcus aureus infections
Maria Manuela de Jesus Guilherme Gaspar
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BEB/098742/2008

Diagnosis and Characterization of the Carotid Atherosclerosis Disease with 3D Ultrasound
Joao Sanches
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-BEB/098749/2008

Quantitative Modeling of Sprouting Angionenesis:
Rui Travasso
Associação para o Desenvolvimento do Departamento de Física da Universidade de Coimbra (ADDFUC/FCT/UC)

PTDC/SAU-BEB/098801/2008

Challenges in chronic wounds treatment: new strategies using polymer therapeutics
Patricia Ferreira da Luz Pereira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BEB/099012/2008

Bio-inspired multiscale interfaces for dental and skeletal reconstruction biomaterials
Rui Vilar
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-BEB/099024/2008

Green and biomimetic strategies for the development of silica/biopolymers/biomolecules composite materials for biomedical and tissue engineering applications
Hermínio José Cipriano de Sousa
PRODEQ - Associação para o Desenvolvimento da Engenharia Química (PRODEQ)

PTDC/SAU-BEB/099141/2008

Development of new drug delivery systems based on bisnaphthalimidopropyl derivatives compounds liposomal formulation for pancreatic cancer and leishmaniasis drug therapy
Sofia Lima
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BEB/099142/2008

Inherent antibacterial activity in peptide-based hydrogels for tissue regeneration
Ana Salomé Rocha do Nascimento Veiga
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BEB/099295/2008

CellNote - Automatic Analysis of Cell Images
Pedro Manuel da Silva Quelhas
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BEB/099347/2008

Transdermal eyelid delivery for treatment of ophtalmic diseases
Sandra Simões
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BEB/099959/2008

DENDRIMAT - New materials for drug/gene delivery based on the self-assembly of dendrimer-chitosan-single stranded DNA conjugates
Helena Maria Pires Gaspar Tomás
Universidade da Madeira (UMA)

PTDC/SAU-BEB/100223/2008

Methodologies to Analyze, Estimate and Simulate Mechanical Properties of Organs from Medical Images
João Manuel Ribeiro da Silva Tavares
INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI/UP)

PTDC/SAU-BEB/100241/2008

Registration and Classification of Biomedical Images: Development of Robust and Efficient Algorithms for Near-Real-Time Clinical Applications
João Manuel Ribeiro da Silva Tavares
INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI/UP)

PTDC/SAU-BEB/100555/2008

Pharmacologically active bioadhesive designed for wound closure
Paula Cristina Nunes Ferreira
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-BEB/100745/2008

Digital technologies in mammography: optimization using Monte Carlo simulation techniques
Ana Isabel Lourenço Pascoal
Universidade Católica Portuguesa (UCP)

PTDC/SAU-BEB/101184/2008

CROSSTALK - Intercellular crosstalking for angiogenesis stimulation in bone regeneration
Pedro Lopes Granja
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BEB/101382/2008

HYBRID.polymers - advanced biopolymers based on elastin and silk
Margarida Paula Pedra Amorim Casal
Universidade do Minho (UM)

PTDC/SAU-BEB/101803/2008

Computerised alerts for intrapartum fetal monitoring
Diogo de Matos Graca Ayres de Campos
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BEB/101916/2008

Functionalized nanoparticles for in vivo targeted drug delivery: application in the treatment of leukemia.
Maria Margarida Canas Mendes de Almeida Cardoso
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-BEB/102219/2008

PELVIMESH - Use of animal models in the study of new synthetic meshes implications in surgery of female pelvic floor dysfunctions
Teresa Mascarenhas
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-BEB/102247/2008

Hybrid electro-optical microfluidic device for single cell analysis
Abel Martin Gonzalez Oliva
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-BEB/102334/2008

3D NANOGENOTOX: Development of (geno)toxicity assays in human-derived 3D cell cultures to characterize the toxicological profile of nanoparticles
Maria João Aleixo da Silva
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-BEB/102377/2008

Investigation of bone disease related changes via piezoresponse force microscopy: a proof of concept
Maria Helena Figueira Vaz Fernandes
Universidade de Aveiro (UA)

PTDC/SAU-BEB/102397/2008

Glass-ceramic scaffolds for regenerative medicine: Improvement of reactivity by surface funtionalization
Maria Helena Figueira Vaz Fernandes
Universidade de Aveiro (UA)

PTDC/SAU-BEB/102440/2008

Optimization of cadaver embalming via dedicated infusor development
Paulo António Ribeiro
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FCTUNL/UNL)

PTDC/SAU-BEB/102475/2008

Novel phosphate glasses for bone regeneration: effect of degradation products on the in vitro mineralization and bone cells response
Maria Helena Figueira Vaz Fernandes
Universidade de Aveiro (UA)

PTDC/SAU-BEB/102492/2008

Biomaterial-mediated bone regeneration in diabetes-compromised conditions
Maria Helena Raposo Fernandes
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-BEB/102511/2008

Design of polyvinyl alcohol networks as supports for protein immobilisation
Maria Henriques Lourenço Ribeiro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BEB/102535/2008

Conception of alternative L-Asparaginase formulations - study of the mechanisms involved on the anti-leukemic activity
Maria Manuela de Jesus Guilherme Gaspar
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BEB/102543/2008

AIEHR, Ambient Intelligence in Electronic Health Records
José Manuel Ferreira Machado
Universidade do Minho (UM)

PTDC/SAU-BEB/102547/2008

Blood flow simulation in arterial networks towards application at hospital
Luísa Maria Abreu Costa Sousa
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-BEB/102552/2008

Silicon nitride ceramic components coated with nanocrystalline CVD diamond for total hip replacement - HIPCerDiam
Margarida Isabel dos Santos Amaral
Universidade de Aveiro (UA)

PTDC/SAU-BEB/102711/2008

FCMotor: Function Characterization of motor brain activity through synchronous Video-EEG-fMRI methods
José Maria Fernandes
Universidade de Aveiro (UA)

PTDC/SAU-BEB/102978/2008

Stimulating tissue regeneration though scaffold design and dynamic stem cell culturing.
Dennis Petrus Link
Universidade do Minho (UM)

PTDC/SAU-BEB/103136/2008

BCGrafts: Vasos sanguíneos artificais de celulose bacteriana
Francisco Miguel Portela da Gama
Universidade do Minho (UM)

PTDC/SAU-BEB/103161/2008

EpitHope - Advanced Biomimetic Regenerative Strategies for Active Targeting Degenerative Articular Cartilage
Helena Paula de Sousa Sepúlveda Azevedo
Universidade do Minho (UM)

PTDC/SAU-BEB/103268/2008

Smart-bioactive catheter dressings for patients undergoing peritoneal dialysis therapy
Isabel Cristina Aguiar de Sousa e Silva Gouveia
Universidade da Beira Interior (UBI)

PTDC/SAU-BEB/103291/2008

In Vivo functional behavior of a new experimental Zirconium-oxide implant with immediate vs. delayed placement: a clinical, radiographic and histological study with beagle dogs.
João Manuel Mendez Caramês
Faculdade de Medicina Dentária da Universidade de Lisboa (FMD/ULisboa)

PTDC/SAU-BEB/103401/2008

Design, synthesis and characterization of innovative nanosystems for targeted delivery of drugs. Applications to anticancer and anti-inflammatory drugs.
MARLENE SUSANA DIONISIO LÚCIO
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-BEB/103614/2008

Task optimization for functional efficiency and injury prevention
Maria António Ferreira de Castro
Escola Superior de Tecnologia da Saúde de Coimbra (ESTEsC/IPC)

PTDC/SAU-BEB/103642/2008

TELME- Evolutionary Intelligence in Cancer Staging Predicting Systems
Antonio Abelha
Universidade do Minho (UM)

PTDC/SAU-BEB/103714/2008

Natural antioxidants in the prevention of photocarcinogenesis: lycopene formulation for skin delivery
Sandra Simões
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BEB/104160/2008

PETPat: Interpretation of PET patterns for the diagnosis of Mild Cognitive Impairment and Alzheimer 's Disease
Margarida Silveira
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-BEB/104161/2008

Nano-Scales and Bone Regeneration
Fernando Alberto Deometrio Rodrigues Alves Guerra
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-BEB/104467/2008

CriticalNano- New green nano releasing systems - a supercritical approach
Ana Rita Cruz Duarte
Universidade do Minho (UM)

PTDC/SAU-BEB/104495/2008

New Tools for Cell Fate Mapping of Regulatory T cells
Carlos Eduardo Tadokoro
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BEB/104578/2008

SpineDrive - An Integrative and Multidisciplinary Approach for Spinal Cord Injury Regeneration
António José Braga Osório Gomes Salgado
Universidade do Minho (UM)

PTDC/SAU-BEB/104638/2008

Polymeric nanofibers as new class of 3D scaffold and their application in stem cell research and tissue engineering
Fouzi Mouffouk
Universidade do Algarve (UAlg)

PTDC/SAU-BEB/104840/2008

Evaluation of Congenital Heart Defects by Three-Dimensional Echocardiography
JOSÉ SILVESTRE SERRA DA SILVA
Associação para o Desenvolvimento do Departamento de Física da Universidade de Coimbra (ADDFUC/FCT/UC)

PTDC/SAU-BEB/104948/2008

Detecção de Micro-estados Cerebrais na Fibromialgia
Joao Sanches
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-BEB/104963/2008

OSTEOCART - A bilayered hybrid structure for osteochondral regeneration
PATRÍCIA BRANDÃO DE ATHAYDE MALAFAYA BAPTISTA
Universidade do Minho (UM)

PTDC/SAU-BEB/104992/2008

Bio-computational study of tinnitus
Maria Fernanda Gentil Costa
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-BEB/105109/2008

Development of a bio-sensor and mathematical models for Biomechanic characterization of the process of bone remodelling
Lídia Carvalho
Universidade de Aveiro (UA)

PTDC/SAU-BEB/105189/2008

StemCellQCM - Acoutic detectors for stem cell adhesion and differentiation
Guilherme Nuno de Passos Correia Matos Ferreira
Universidade do Algarve (UAlg)

PTDC/SAU-BEB/105251/2008

SENSORTEX - Biomedical Device for Pressure Ulcers Prophylaxis on Immobilized or Disabled Patients
Mário Figueiredo Nunes
Universidade da Beira Interior (UBI)

PTDC/SAU-BEB/105272/2008

Fibres2Bone - Development of highly functional biodegradable three-dimensional structures, integrating nanofiber meshes produced by the electrospinning technique, for bone tissue engineering applications.
Nuno Neves
Universidade do Minho (UM)

PTDC/SAU-BEB/105373/2008

Displacement-frequency transform applied to Doppler Ultrasound blood flow signals
Ana Isabel Pereira Martins Leiria
Universidade do Algarve (UAlg)

PTDC/SAU-BEB/105376/2008

Extraction of quantitative features from mammary lesions in elastografy images
Ana Isabel Pereira Martins Leiria
Universidade do Algarve (UAlg)

PTDC/SAU-BEB/105439/2008

Biomatrix - Engineering Cell Instructive Biomaterials to Copycat Nano-interaction of Cells in Bone and Cartilage Tissues
Rui L Reis
Universidade do Minho (UM)

PTDC/SAU-BEB/105503/2008

External radiotherapy planning systems quality control of oncology head and neck pathologies using advanced phantoms and multimodal tomographic imaging
João António Miranda dos Santos
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-BEB/105690/2008

Design and Analysis of the Shoulder Prosthesis
João Orlando Marques Gameiro Folgado
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-BEB/105707/2008

Cement on cement in revision of total hip joint replacement- One feasible solution.
Fernando Simões
Instituto Superior de Engenharia de Coimbra (ISEC/IPC)

PTDC/SAU-BEB/107982/2008

Multi-B-Vessel: Multilayered living scaffold for vascular tissue engineering
Jorge Alexandre Monteiro de Carvalho e Silva
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-BEB/107989/2008

InSituScaf- Natural-origin smart scaffolds with the ability of in situ formation of pores: a novel strategy for bone tissue engineerind and regenerative medicine
Rui L Reis
Universidade do Minho (UM)

PTDC/SAU-BEB/108064/2008

Study of the effects of oclusal forces in the mandibule body and in Tempero Mandibular Joint
Maria João Pascoal Rodrigues César Machado
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-BEB/108085/2008

TCcad - Computer Aided Diagnosis in Brain Computer Tomography Screening
Victor Alves
Universidade do Minho (UM)

PTDC/SAU-BEB/108220/2008

Development of drug delivery systems in dental root canal sealers
Ana Isabel Henriques Dias Fernandes
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-BEB/108452/2008

DISCOS: Intervertebral DISC strain using Optical fiber Sensors
ILDA ABE
Universidade de Aveiro (UA)

PTDC/SAU-BEB/108472/2008

Zirconia Ageing in Fixed Prosthodontics
João Carlos Antunes Sampaio Fernandes
INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI/UP)

PTDC/SAU-BEB/108498/2008

CHRISTINA - Critical Health Care Assisted Through Integrated Monitoring and Evaluation of Biophysiological Parameters
Mario Marques Freire
Universidade da Beira Interior (UBI)

PTDC/SAU-BEB/108552/2008

Improving the vision of colour-deficient observers for natural scenes
Sérgio Miguel Cardoso Nascimento
Universidade do Minho (UM)

PTDC/SAU-BEB/108659/2008

DYNART - Novel treatment approaches for articular cartilage defects through integrated mesenchymal cell isolation methods and dynamic cell culturing
Rui Sousa
Universidade do Minho (UM)

PTDC/SAU-BEB/108740/2008

Arthros ReGENEration - Gene enhanced tissue engineering approach combined with a new generation of natural injectable smart systems for articular cartilage regeneration
Joao Filipe Colardelle da Luz Mano
Universidade do Minho (UM)

PTDC/SAU-BEB/108748/2008

Iris colorimetry by hyperspectral imaging
JOSE MANUEL MEDINA RUIZ
Universidade do Minho (UM)

PTDC/SAU-BEB/108768/2008

Evaluation of changes on two-phase flow of particles designed for dry powder inhalers due to surface energetics modifications
João Fernandes de Abreu Pinto
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BEB/108943/2008

Studying of ANS involvement in ALS patients: towards advanced procedures of signal processing and modelling in dedicated equipment for a better diagnosis and treatment
Maria Teresa Haderer de la Peña Stadler
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-BEB/109071/2008

LOTUS: biomimetic control of the wettability of biomaterials surface throughout extreme ranges to tailor cell adhesion or protein adsorption
Joao Filipe Colardelle da Luz Mano
Universidade do Minho (UM)

PTDC/SAU-NEU/098123/2008

Role of Transthyretin proteolytic activity in A-Beta degradation, accumulation and toxicity
Isabel dos Santos Cardoso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/098186/2008

The Role of Protein Phosphatase 1 in the Molecular Mechanisms Underlying Early-Onset Torsion Dystonia
Edgar Figueiredo da Cruz e Silva
Universidade de Aveiro (UA)

PTDC/SAU-NEU/098421/2008

CHANGES IN GABAergic SYNAPTIC TRANSMISSION IN BRAIN ISCHEMIA
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/098456/2008

Study and characterization of brain damage induced by GBS neonatal meningitis using the natural infection route
Paula Ferreira
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-NEU/098507/2008

Unraveling the Neuronal Circuits Underlying Female Receptivity
Maria Luisa Caramalho Abrunhosa Vasconcelos
Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (FC Champalimaud)

PTDC/SAU-NEU/098741/2008

Study of the effects of EGCG on a mouse model of FAP for a possible therapeutic strategy
Maria Rosário Almeida
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/098747/2008

Preconditioning triggered by Carbon monoxide: new strategies to prevent brain damage due to hypoxia-ischemia and reperfusion
Helena Luisa de Araujo Vieira
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-NEU/098748/2008

Dissecting the regeneration enhancer properties of proteins activated/upregulated following conditioning lesion.
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/098844/2008

Modulation of axonal transport and synaptic dysfunction: a novel role for tauroursodeoxycholic acid
Rita Cruz Coelho de Mira Ramalho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NEU/098990/2008

Protein aggregate formation, dynamics and clearance in neurodegenerative disorders: parkin and PKCgamma mutants as a model
Isabel Alonso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/099003/2008

Functional identification of oligodendrocytes in neural stem cell cultures and graf efficiency in brain remyelination
Joao Jose Oliveira Malva
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/099133/2008

Establishing biomarkers for Huntington´s disease : a proteomic approach
Pedro Miguel Leal Rodrigues
Centro de Ciências do Mar (CCMar)

PTDC/SAU-NEU/099189/2008

Characterization of the role of plasmalogens as antioxidants
Pedro Miguel Teixeira Brites
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/099192/2008

Animal models as a tool for exploring new frontiers of bilirubin-induced neurological pathology
Adelaide Fernandes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NEU/099244/2008

Optimization of the Hartmann-Shack Sensibility for Hyperspectral Wavefront Analysis in Refractive and Cataract Surgery
Paulo Torrão Fiadeiro
Universidade da Beira Interior (UBI)

PTDC/SAU-NEU/099392/2008

Common pathways to chronic pain and depression: a clinical and experimental study
Fani Lourença Moreira Neto
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/099426/2008

Contribution of neurotrophins to the overactive bladder. Experimental and clinical study.
Célia da Conceição Duarte Cruz
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/099508/2008

A visual view on the reading deficit in dyslexia
Marieke van Asselen
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-NEU/099543/2008

Function and Infectivity of Prions During Neural Differentiation of Embryonic Stem Cells
Eduardo Pinho Melo
Universidade do Algarve (UAlg)

PTDC/SAU-NEU/099593/2008

Neuroplasticity of the emotional and cognitive interactions with the supraspinal pain control system after chronic neuropathic pain: are they reverted with antidepressants?
Armando Almeida
Universidade do Minho (UM)

PTDC/SAU-NEU/099678/2008

Effect of methamphetamine on adult brain neurogenesis: new perspectives for the recovery of cognitive function
Ana Paula Pereira da Silva Martins
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-NEU/099708/2008

Modulation of the protective and deleterious roles of astrocytes by adenosine receptors in Alzheimer's disease
PAULA MARIA GARCIA AGOSTINHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/099853/2008

Role of the adenosine A2A receptors in chronic stress - implications for learning and memory
Luisa Vaqueiro Lopes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/099978/2008

Imaging exocytotic apparatus during single vesicle fusion in a cell free neuroendocrine system
Maria Paula Polónia Gonçalves
Universidade de Aveiro (UA)

PTDC/SAU-NEU/100002/2008

Design, synthesis and biological assessment of new hybrid multipotent compounds as anti-Alzheimer drugs
Maria Carmo Damaso Costa Silva A Carreiras
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NEU/100046/2008

DTDrugs. Dual-Target-Directed Drugs for Parkinson's Disease
Fernanda Borges
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-NEU/100136/2008

Neural Mechanisms Involved in Mate Choice
Susana Q Lima
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NEU/100208/2008

Characterization of a neurogenic program activated by the proneural factor Mash1
Diogo Pinto da Cruz Sampaio e Castro
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NEU/100246/2008

Brain adaptation to stressful stimuli: the good side of mitochondrial reactive oxygen species
PAULA ISABEL DA SILVA MOREIRA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/100360/2008

Into the basis of insulin role in neuronal function
Pedro Afonso dos Santos Baltazer de Lima
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-NEU/100368/2008

Estrogen and androgen induction of transthyretin in the choroid plexus: impact on cognitive function and amyloid beta deposition
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/SAU-NEU/100472/2008

Insights into the impact of diabetes on exocytosis in the hippocampus: implications for glutamatergic and gabaergic neurotransmission
António Francisco Rosa Gomes Ambrósio
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-NEU/100532/2008

Neuronal aging associated with methamphetamine abuse
Pedro Miguel Martins de Almeida Melo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/100669/2008

Time-frequency analysis methods to quantify the time-varying microstructure of sleep EEG spindles
Manuel Duarte Ortigueira
Instituto de Desenvolvimento de Novas Tecnologias (UNINOVA)

PTDC/SAU-NEU/100724/2008

Glycosylation and Lewis X motif in neuronal tissue.
Júlia Carvalho Costa
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-NEU/100818/2008

Glycinergic transmission in hippocampus - potential role in epilepsy and seizures
Ana Maria Ferreira Sousa Sebastião
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/100851/2008

Pain modulation from the brain: changes during chronic pain installation and possibilities of interference
Isaura Ferreira Tavares
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/100862/2008

NFA - NeuroFeedback Adaptativo - Aplicação a uma população com Transtorno de Defice de Atenção e Hiperactividade (TDAH)
Agostinho Cláudio da Rosa
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-NEU/101136/2008

APP phosphorylatable C-terminal motifs are key regulatory elements and impact the pathological development of Alzheimer's Disease
Odete A B da Cruz e Silva
Universidade de Aveiro (UA)

PTDC/SAU-NEU/101343/2008

Prrxl1: Building the Pain Connection
Filipe Almeida Monteiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/101383/2008

Botulinum toxin as a novel treatment for benign prostate hyperplasia: experimental and clinical study
António Avelino Ferreira Saraiva da Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/101396/2008

Identification of the physiological roles of calpains in the control of cell proliferation and migration in the nervous system: relevance for recovery from brain ischemia
Inês Maria Pombinho de Araújo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/101521/2008

Interplay between endothelial cells and neurons in Alzheimer's disease: towards novel brain repair strategies
Cláudia Maria Fragão Pereira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/101545/2008

Postoperative delirium in elderly patients: risk stratification, diagnosis and prognosis with biomarkers
Adriano Supardo Vaz Serra
Hospitais da Universidade de Coimbra, E.P.E (HUC/UC)

PTDC/SAU-NEU/101562/2008

The choroid plexus transcriptome: implications to brain homeostasis
Joana de Almeida Santos Pacheco Palha
Universidade do Minho (UM)

PTDC/SAU-NEU/101628/2008

RAGE- a multiligand cell surface receptor
Ana Margarida Moreira Leitão de Barros Martins Damas
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/101636/2008

The dynamics of TTR amyloid formation and disruption
Ana Margarida Moreira Leitão de Barros Martins Damas
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/101752/2008

Cross talk between neurotrophic factor receptors (TrkB) and adenosine A2A receptors: implications for Amyotrophic Lateral Sclerosis (ALS)
Joaquim Alexandre Ribeiro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/102037/2008

Role of the RhoGTPases cdc42 and rac1 in axon ensheathment and in the formation of myelin sheaths during PNS myelination and remyelination
Joao Carlos Bettencourt de Medeiros relvas
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/102043/2008

An in vivo imaging approach to follow protein aggregation, microglial activation and neuronal cell function in synucleinopathies
Maria Teresa Albuquerque Santos Faria Pais
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/102119/2008

Peripheral Neuronal Damage Associated with Experimental Osteoarthritis
José Manuel Pereira Dias de Castro Lopes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/102208/2008

The social brain: how social interactions sculpt the brain?
Rui Oliveira
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NEU/102338/2008

Uncovering the neuroprotective role of adenosine in diabetic retinopathy
Paulo Fernando Martins dos Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/102538/2008

GDNF and CDNF in brain aging: guilty or not guilty?
Graça Maria Fernandes Baltazar
Universidade da Beira Interior (UBI)

PTDC/SAU-NEU/102810/2008

Inhibitory Control of Behavior: Dissection of Cortical Output Circuits
Masayoshi Murakami
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NEU/102931/2008

Enhancing the computational intelligence in neurofeedback therapy - Application to attention deficit hyperactivity disorder (ECINF-ADHD)
Carlos Fernandes da Silva
Universidade de Aveiro (UA)

PTDC/SAU-NEU/103406/2008

Identification of neuroregeneration signalling pathways mediated by the APP protein
Sandra Isabel Moreira Pinto Vieira
Universidade de Aveiro (UA)

PTDC/SAU-NEU/103639/2008

On the role of VIP receptors in hippocampal dependent cognition and synaptic plasticity: evaluation of the therapeutic potential of VPAC1 receptor antagonists to ameliorate the cognitive deficits in TLE
Diana Lina Jerónimo da Cunha Reis
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/103720/2008

Regulation of synaptogenesis by kinase Cdk5 and Shank3: Biochemical and Structural Studies
Margarida Archer Frazão
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-NEU/103932/2008

Gst pi at the Crossroad of UPS and Autophagy Avenues
Maria João Carlos da Silva Gama
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NEU/103953/2008

Calorie Restriction, Longevity and Sensorymotor Behaviour
Agavni Petrosyan
Universidade do Minho (UM)

PTDC/SAU-NEU/104047/2008

Influence of nutritional factors and interaction with ethanol consumption in cellular signalling systems related to oxidative stress in the Rat hippocampal formation
José Paulo Alves Vieira de Andrade
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/104119/2008

Psychological factors and Stress Vulnerability in Obesity and Metabolic Syndrome - The Role of Serotonin and Hypothalamic-Pituitary- Adrenal Axis
Silvia Ouakinin
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-NEU/104130/2008

A transcriptomic approach in a Parkinson cell model using uncharacterized plant polyphenol enriched fractions exhibiting potent antioxidant activities
Ricardo Manuel de Seixas Boavida Ferreira
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-NEU/104859/2008

Pain and hypertension. Is angiotensin II the endogenous link in the central nervous system?
António Albino-Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/104977/2008

Study of physiopathology of Negative Symptoms of Schizophrenia and it's influence on the autonomic response to emotion
Maria Luisa Figueira
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-NEU/105038/2008

Astrocyte-microglia crosstalk: when injured neurons get in the way
Carla Sofia Pais Fonseca
Universidade da Beira Interior (UBI)

PTDC/SAU-NEU/105144/2008

Metabolic profile and adipokines in mild cognitive impairment - influence on conversion to Alzheimer´s disease
Armando José Nunes Harrington Sena
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-NEU/105215/2008

From phosphorylation to cleavage: switching on alpha-synuclein aggregation and toxicity
Tiago Outeiro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NEU/108005/2008

CHEMICAL MEDIATORS OF THE NEUROTROPHIC EFFECTS OF ESTROGEN. In vitro study of hypothalamic cells
Maria Dulce Cordeiro Madeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/108018/2008

Neuroprotective role of estrogen in ethanol toxicity
Maria Dulce Cordeiro Madeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/108052/2008

Localization and metabolism of APP controlling synaptic degeneration in animal models of Alzheimer's disease
Catarina Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/108137/2008

Female gender-specific effects of seizures on brain structure and function
NIKOLAY VSEVOLODOVICH LUKOYANOV
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/108750/2008

Mathematical processing of biological signs for the analysis of autonomic nervous system function in patients with orthostatic intolerance
Jose Luis Bliebernicht Ducla Soares
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-NEU/108823/2008

Spina bifida: timing of in utero cytopatholgy changes in a mouse model of the disease.
Joaquim Luís Ramos Torres Couto Reis
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-NEU/108832/2008

CONCERTED PURINE AND TACHIKININ SIGNALING IN THE MYENTERIC PLEXUS: ARE THERE FUNCTIONAL REPERCUSSIONS?
Maria de Fátima Oliveira Ferreirinha
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ESA/098006/2008

Communication in Primary Health Care. Evaluation of General Practitioners´ and Community Pharmacists´ Patient Interaction.
Afonso Miguel das Neves Cavaco
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ESA/098058/2008

Clinical, epidemiological and functional relevance of Helicobacter pylori CagA EPIYA motifs and vacA intermediate region
Ceu Figueiredo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ESA/098234/2008

RELIES - Relatedness, identities and science on couples's decisions about the fates of embryos
SUSANA MANUELA RIBEIRO DIAS DA SILVA
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ESA/098249/2008

BioCLOCK- Night Shift work, circadian disruption and the risk of cancer: Influence of night shift work on hormone levels that may affect prostate cancer risk
João Paulo Fernandes Teixeira
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-ESA/098313/2008

Prognostic indicators for patients with undifferentiated connective tissue disease
Constantin Fesel
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ESA/098513/2008

A Comprehensive View of Malaria in Equatorial Guinea
Ana Paula Martins dos Reis Arez
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/098608/2008

INTERPLANT - Herbal product-drug interactions: Madeira archipelagos - a case study
Paula C Castilho
Universidade da Madeira (UMA)

PTDC/SAU-ESA/098661/2008

AntiPep- EVALUATION OF THE POTENTIAL USE OF ANTIMICROBIAL PEPTIDES TO CONTROL BACTERIAL ADHESION AND BIOFILM FORMATION IN MEDICAL SURFACES
Maria Olívia Baptista de Oliveira Pereira
Universidade do Minho (UM)

PTDC/SAU-ESA/098974/2008

NANORISK - Study of health effects of nanoparticulate emitted in indoor environments
João Fernando Pereira Gomes
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-ESA/098997/2008

Affective-Emotional disorders - Prevelence of Depression, Anxiety and Stress in Primary Care Settings
João Luís Alves Apóstolo
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/099269/2008

Determination of the rate of infection by Human Papillomavirus and its molecular characterization, by Neisseria gonorrhoeae and Chlamydia trachomatis in 1000 students of the University of Minho, from 17 to 19 years.
Henedina da Conceição Araújo Antunes
Universidade do Minho (UM)

PTDC/SAU-ESA/099429/2008

Glanzmann Thrombastenia in Portugal - Development and application of a new powerful diagnostic tool
Nuno Fernando Duarte Cordeiro Correia dos Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ESA/099448/2008

Aedes aegypti in Madeira archipelago. Risk assessment for the emergence of Dengue and Chikungunya fever; tools for vector control.
Carla Alexandra Gama Carrilho da Costa Sousa
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/099574/2008

An integrated approach to study the persistence of the human pathogen Listeria monocytogenes
Luisa Brito
Instituto Superior de Agronomia (ISA/ULisboa)

PTDC/SAU-ESA/099699/2008

Comparative analysis of gonorrhea dynamics and evolution in antibiotic resistant and non-resistant communities
Marcos Perez Losada
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ESA/099765/2008

Cognitive impact of environmental pollutants: development of a realistic mouse model of continued human exposure to subchronic levels of TCDD and Aroclor 1254
Diana Lina Jerónimo da Cunha Reis
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ESA/099786/2008

Educational intervention at school as an deteminant of healthy behaviours in adolescents
Providencia Pereira Marinheiro
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/099898/2008

Nutrient and contaminant determination in human milk and their relationship with the child development.
Sandra Rita Pedroso Félix Madeira
EIA - Ensino, Investigação e Administração, SA (EIA)

PTDC/SAU-ESA/100058/2008

A comprehensive and family centered approach to the management of COPD
Alda Marques
Universidade de Aveiro (UA)

PTDC/SAU-ESA/100065/2008

Polycyclic Aromatic Hydrocarbons in traditional meat products: prevalence study and development of selective capture strategies to reduce contamination
Teresa de Jesus da Silva Matos Nolasco Crespo
Instituto Superior de Agronomia (ISA/ULisboa)

PTDC/SAU-ESA/100137/2008

Surfactants in the Prophylaxis of Sexually Transmitted Infections and in Oral Hygiene
Otília Vieira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ESA/100226/2008

Improvement of health outcomes in elderly associated with Pharmacotherapy Follow-up
Fernando Fernandez-Llimos
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ESA/100271/2008

Children Exposure to Mycotoxinas: approaching risk assessment
Paula Cristina da Cruz Oliveira Soromenho de Alvito
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-ESA/100275/2008

Environment and Health in children day care centres (ENVIRH)
NUNO MANUEL BARREIROS NEUPARTH
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ESA/100287/2008

Study of the Prevalence and Risk Factors of Early Childhood Caries
Mário Filipe Cardoso de Matos Bernardo
Faculdade de Medicina Dentária da Universidade de Lisboa (FMD/ULisboa)

PTDC/SAU-ESA/100336/2008

Familiar dynamics of very old people: caring for a better life (DIFAI)
Maria Arminda da Silva Mendes Carneiro da Costa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ESA/100413/2008

Looking for biomarkers of lung cancer: a cytogenetic and epigenetic approach of Cr(VI)-induced lung cancer using in vitro cell models
Maria Carmen Alpoim
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ESA/100469/2008

Atherogenic risk markers in obese Portuguese adolescents. Genetic predisposition and modifications imposed by regular physical exercise
LUÍS FILIPE BARBOSA AMADO BELO
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ESA/100731/2008

Susceptibility of building materials to the growth of fungi
Gabriela Ventura Alves da Silva
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ESA/100732/2008

NATIONWIDE NETWORK OF GAMMA CAMERAS FOR RESPONSE IN A RADIOLOGICAL EMERGENCY SITUATION IN PORTUGAL
Pedro Manuel Peixoto Teles
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-ESA/100770/2008

PEER: Peer-project engagement and evaluation research in Portugal, Brazil and Cape Verde
Irma Brito
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/100789/2008

Impact of the reorganization of the National Health Service: implications on citizen's health
Vítor Manuel Costa Pereira Rodrigues
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/SAU-ESA/100805/2008

Needs of first time parents in postpartum period
Isabel Margarida Marques Monteiro Dias Mendes
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/100974/2008

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA): from genetic diversity to virulence potential
Hermínia de Lencastre
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-ESA/101023/2008

Epidemiology, ethiology and genetic characterization of cardiovascular diseases in the Azores population
Cláudia Margarida Aguiar Castelo Branco
Hospital do Divino Espírito Santo de Ponta Delgada, EPE (HDESPD, EPE)

PTDC/SAU-ESA/101075/2008

Endocrine disruption and male fertility
João RamalhoSantos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ESA/101186/2008

Studies for the establishement of GRP as a biomarker for vascular calcification
Dina Costa Simes
Centro de Ciências do Mar (CCMar)

PTDC/SAU-ESA/101228/2008

Forensic Entomology: Morphometric and Molecular databank (mtDNA) to identify species (Diptera and Coleoptera) with forensic interest.
MARIA TERESA FERREIRA RAMOS NABAIS DE OLIVEIRA REBELO
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ESA/101253/2008

BIOBORN - Assessment of Contaminants and Biomarkers in new born children from Different Environmental Backgrounds
Maria Angela Pereira Serafim
Universidade do Algarve (UAlg)

PTDC/SAU-ESA/101283/2008

Epidemiology of hip fractures in Portugal: the first decade of the XXI Century.
Maria de Fátima Rodrigues Pereira de Pina
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-ESA/101291/2008

Tracking the hidden epidemics: surveying Chlamydia trachomatis and Neisseria gonorrhoeae infections in adolescents
Maria José Borrego
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-ESA/101309/2008

Health, Risk and Governmentalisation
Maria Vitória da Graça Pinto Guerra Mourão
Instituto Superior de Ciências Sociais e Políticas (ISCSP/Ulisboa)

PTDC/SAU-ESA/101357/2008

Study of the genetic variability of Portuguese populations of the European tick Ixodes ricinus Linnaeus, 1758 one of the main vectors of Lyme Borreliosis, Human Anaplasmosis and Spotted Fever Group Rickettsiosis
Maria Margarida Santos Silva Serejo
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-ESA/101422/2008

Study of the prevalence and clinical as well as serological features of food allergies in Portuguese children and adults
Luis Manuel Taborda Barata
Universidade da Beira Interior (UBI)

PTDC/SAU-ESA/101471/2008

Tuberculosis Endemy in Portugal - trends, determinants and prospects.
Carla do Rosário Delgado Nunes de Serpa
Escola Nacional de Saúde Pública (ENSP/UNL)

PTDC/SAU-ESA/101514/2008

Building the Basis for Medico-Legal Identification and Cause of Death Determination from Badly Preserved and Skeletonised Human Remains
Hugo Cardoso
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ESA/101625/2008

Monitoring sociodemographic and pathophysiological factors associated with acquisition of HIV and progression to AIDS: pilot study for an HIV cohort in Portugal
Leonie Rita Prasad
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/101692/2008

Suicidal behaviors among Portuguese youth. The “I” and the “we” and the family's point of view.
José Carlos Pereira dos Santos
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/101709/2008

Predictive Risk Assessment in Occupational Toxicology: Control and Prevention of Neurotoxicity Induced by Chronic Exposure to Manganese Compounds
Ana Paula Marreilha dos Santos
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ESA/101743/2008

Gene-environment interactions in health and disease, a Portuguese survey.
Marta Barreto
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ESA/101827/2008

Determination of Outdoor Airborne Allergens by Immunoassays
Rui Manuel de Almeida Brandao
Universidade de Évora (UE)

PTDC/SAU-ESA/101930/2008

ENVIRONMENTAL INJUSTICE AT PORTO USING TUBERCULOSIS, AIDS AND HEPATITIS AS INDICATORS (HEI)
Ana Maria Rodrigues Monteiro de Sousa
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/101965/2008

HIV-1 in intravenous drug-users: a multivalent approach to virus diversity analysis.
Ricardo Manuel Soares Parreira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/102000/2008

Occurrence of multidrug-tolerance genetic systems in conventional vs organic laying hens production. Risk assessment on their transfer through the food chain.
Paula Sá-Pereira
Instituto Nacional de Engenharia, Tecnologia e Inovação (INETI)

PTDC/SAU-ESA/102367/2008

GenFA- Occupational Exposure to Formaldehyde. Genotoxic Damage and Susceptibility evaluation in Pathology Anatomy Laboratory workers
João Paulo Fernandes Teixeira
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ESA/102435/2008

Screening of potential molecular markers for stage determination in Human African Trypanosomiasis.
Nuno Miguel Carmona de Jesus Rolão
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/102466/2008

Nonagerian and centenarian health modulated by oxidative stress
Henrique Almeida
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ESA/102493/2008

Symptoms influence in daily living activities of chronic ambulatory patients
Maria João Costa Santos Mattos Marques Gomes
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ESA/102551/2008

Giardia and other intestinal parasites in children from Lisbon
Sónia Chavarria Alves Ferreira Centeno Lima
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/102635/2008

Water Disinfection By-products in Indoor Swimming-pools: Environmental Exposure, Reproductive Effects and Genotoxicity Evaluation
Ana Sofia Vilhena Fernandes Pereira Cardoso
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-ESA/102648/2008

Validation of spectroscopic methods for epidemiological analysis and detection of resistance mechanism in clinical relevant bacteria
Luisa Maria Sobreira Vieira Peixe
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ESA/102724/2008

Work Conditions and Health Effects: A Methodological Contribution for it´s Assessment and Surveillance
Maria Filomena Araújo da Costa Cruz Carnide
Faculdade de Motricidade Humana (FMH/ULisboa)

PTDC/SAU-ESA/102743/2008

Geochemical and anthropogenic contribution for the incidence of cancer in the hydrographic basin of the river Mondego (GeoMoon)
ABEL DE OLIVEIRA MARTINS DE CARVALHO
Instituto Politécnico de Coimbra (IPC)

PTDC/SAU-ESA/102768/2008

Planning of hospital discharge for the stroke patient and the informal caregiver
Maria dos Anjos Coelho Rodrigues Dixe
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/102775/2008

The Impact of Air Pollution on the Worsening of Respiratory Diseases in Northern Portugal
Fernando Martins
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-ESA/102990/2008

Chlamydia trachomatis: social and culture factors related to infection and association of genotypes to clinical syndromes
Filomena Martins Pereira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/103018/2008

Evolution of antibiotic resistance
Isabel Gordo
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ESA/103102/2008

Sexual Dysfunction Observational Study in Portugal (SEXOS): Treatment-seeking behavior of sexual dysfunctions
José Manuel Domingos Pereira Miguel
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ESA/103117/2008

Mental Health literacy: Internet-based program for adolescents and young
Luís Manuel de Jesus Loureiro
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/103154/2008

Predicting factors in oral health and its impact on the quality of life throughout the life cycle
Maria Madalena Jesus Cunha Nunes
Instituto Politécnico de Viseu (IPV)

PTDC/SAU-ESA/103331/2008

Prevalence of cognitive deficits and muscular strength changes associated with polymorphisms of angiotensin converting enzyme in elderly portuguese individuals
Jose Manuel Lage Campelo Calheiros
Universidade da Beira Interior (UBI)

PTDC/SAU-ESA/103397/2008

Vectorial competence and capacity of the most abundant mosquitoes from Portugal to some arboviruses circulating in the Mediterranean, in face of the current climatic changes. VECOMPORT
António Paulo Gouveia de Almeida
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/103451/2008

Genetics of hearing loss in children and elderly - improving health and quality of life.
Maria Helena Caria
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ESA/103511/2008

Prospective study about the determinants and impact of medication adherence and therapeutic change in the control of arterial hypertension, among a cohort of immigrant and non-immigrants at the primary care level.
Evangelista Casimiro Rocha
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ESA/103595/2008

Pro-active approaches for ready-to-eat microbial food safety improvement
HELENA MARIA ALVES DA SILVA
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-ESA/103607/2008

Obesity and physical activity. A intervention study in children
VÍTOR PIRES LOPES
Instituto Politécnico de Bragança (IPBragança)

PTDC/SAU-ESA/103755/2008

VirtualECare - An Ambient Assisted Living
Paulo Novais
Universidade do Minho (UM)

PTDC/SAU-ESA/103812/2008

Portugal Smiling
FRANCISCO JOAO SALVADO E SILVA
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-ESA/103825/2008

Benefits and risks of fish products consumption: A benefit-risk analysis based on the occurrence and bioaccessibility of n-3 PUFA and Selenium, Mercury and Arsenic in raw and cooked products (GOODFISH)
Maria leonor Martins Braz de Almeida Nunes
Instituto Português do Mar e da Atmosfera, I. P. (IPMA)

PTDC/SAU-ESA/103946/2008

Study of the Impact of New Immunosuppressive Therapy in Kidney Transplant Recipients
Carla Maria Teixeira de Barros Branco Ló
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ESA/103959/2008

Cancer Quality of Care and Chemotherapy Outcomes Research: The Portuguese Cancer Outcomes Research Study
ANA PAULA MECHEIRO DE ALMEIDA MARTINS SILVESTRE CORREIA
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ESA/104293/2008

Development of a nanoparticulate vaccine for heterologous prime-boost immunization against malaria
Lídia Maria Diogo Gonçalves
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ESA/104319/2008

Factors associated with adherence to consensus guidelines for women's preventive care: preferences related to time and risk and non-preference-based barriers
Antonio Manuel Gouveia de Oliveira
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ESA/104362/2008

ImpactMine - Health effects of contamination resulting from mining activities
João Paulo Fernandes Teixeira
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-ESA/104383/2008

Risk markers in women victims of domestic violence. Gene X Environment interaction study
Teresa Maria Salgado de Magalhães
Instituto Nacional de Medicina Legal e Ciências Forense, I.P. (INMLCF/MJ)

PTDC/SAU-ESA/104607/2008

Legionella pneumophila: an innovative epidemiological tool based on virulence traits.
António Verissimo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ESA/104740/2008

FOODVALUE: Functional and nutritional value of traditional Portuguese recipes and implications of their ingredients and processing on nutritional quality
Maria Daniel Barbedo Vaz Ferreira de Almeida
Faculdade de Ciências da Nutrição e Alimentação (FCNA/UP)

PTDC/SAU-ESA/104792/2008

Identification of virulence markers with therapeutic significance in Prototheca infections.
Gertrude Averil Baker Thompson
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ESA/104794/2008

Real-time forecast of Influenza and Dengue fever: A framework integrating surveillance, data analysis and mathematical modeling.
Flávio Codeço Coelho
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ESA/104875/2008

Repository of health measurement instruments
Pedro Augusto Melo Lopes Ferreira
Centro de Estudos e Investigação em Saúde da Universidade de Coimbra (CEISUC)

PTDC/SAU-ESA/104904/2008

Assessment of the survival to abiotic stress factors among multi-resistant Escherichia coli, Enterococcus spp. and Salmonella sp.
Paulo Manuel Rodrigues Martins da Costa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ESA/104942/2008

Coimbra's oldest old: functional status and services utilization
Rogério Manuel Clemente Rodrigues
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/104947/2008

Characterization and genotyping of portuguese strains of Francisella tularensis
Líbia Maria Marques Zé-Zé
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ESA/105052/2008

Chronic whole-body vibration and prostate cancer
MARIA JOÃO FEYTOR PINTO RODRIGUES DE OLIVEIRA DE MEIRELES MOREIRA
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ESA/105056/2008

Dynamics of resistance to antibiotics in heterogeneous environments: the role of antibiotic doses and of the bacterial mating system.
sara Magalhães
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ESA/105071/2008

Epidemiological and genetic characterisation of a hybrid zone between incipient species of the malaria vector Anopheles gambiae
João Pedro Soares da Silva Pinto
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/105107/2008

Radioactivity in cigarette smoke, radon daughters and lung cancer
Fernando da Piedade Carvalho
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-ESA/105174/2008

Study of genetics and metabolic determinants of obesity in university students at Algarve´s region
Claudia Henriqueta Rita Marinho Valente Coutinho
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ESA/105178/2008

Assessing critical doses to optimize radiological protection in CT-fluoroscopy guided interventional procedures
João António Miranda dos Santos
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ESA/105179/2008

Ferramentas analíticas para o estudo do efeito da radiação cósmica em pilotos de linha aérea.
Pedro Tavares
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-ESA/105239/2008

Comparative study of antimicrobial resistance in Escherichia coli and Enterococcus spp. isolated from humans, their pets (dog and cat) and home environment
Paulo Manuel Rodrigues Martins da Costa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ESA/105394/2008

The Importance of Gastroenteritis Caused by Norovirus Infection in Portugal-investigation of immunological factors associated with human susceptibility and resistance to this pathogen
Claudia Istrate
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/105402/2008

Biological, antigenic and molecular characterization of viruses isolated from Culicidae mosquitoes in Portugal
Líbia Maria Marques Zé-Zé
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-ESA/105406/2008

Methods of representative sampling and measurement in the assessment in situ of indoor air quality (IAQ-RAM)
Eduardo de Oliveira Fernandes
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ESA/105428/2008

Tracking for epidemic and virulent nosocomial multidrug-resistant Enterococcus clones. A multicenter approach.
Rosario Mato Labajos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-ESA/105500/2008

Nursing contributions and challenges to the promotion of self-care in the elderly: the case of motor activity in the elderly with CVA
José Manuel de Matos Pinto
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-ESA/105505/2008

Bio(sensors) for detection/quantification of pathogenic bacteria in water of human consumption
Gerardo González Aguilar
Instituto de Engenharia de Sistemas e Computadores do Porto (INESC Porto/FE/UP)

PTDC/SAU-ESA/105525/2008

Inactivation of microorganisms in hospital wastewaters by a novel photochemical technique of potentially low environmental impact.
Maria da Graça de Pinho Morgado Silva Neves
Universidade de Aveiro (UA)

PTDC/SAU-ESA/105585/2008

National Study about the Prevalence of chronic wounds
Maria João Filomena Santos Pinto Monteiro
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/SAU-ESA/105704/2008

Project of Intervention - AIDS in Mozambique
Maria João Filomena Santos Pinto Monteiro
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/SAU-ESA/105719/2008

Alternative method for treatment hospital wastes contaminated with citotoxic compounds
Rui Manuel Pereira Ruivo
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-ESA/107921/2008

Molecular characterization of infectious agents associated to cancer development in female sex workers from Northern Portugal: study of HPV and Chlamydia
RUI Manuel de MEDEIROS Melo Silva MEDEIROS
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ESA/108002/2008

BacMobile - Mobilization of antibiotic resistance determinants in the hospital environment.
Sónia Alexandra Leite Velho Mendo Barroso
Universidade de Aveiro (UA)

PTDC/SAU-ESA/108028/2008

Patients' and Health Professionals' Reported Outcomes in Inflammatory Bowel Disease
Fernando José Magro Dias
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ESA/108183/2008

Mental Illness Stigma. Study of prevalence amongst healthcare students, and evaluation of an educational programme.
Maria Luísa Brites Parreira Coelho Vieira de Campos
Universidade Católica Portuguesa (UCP)

PTDC/SAU-ESA/108614/2008

Effectiveness of the Portuguese smoke-free law in relation to the health protection of the leisure-hospitality sector' workers: cross-sectional study based on environmental and biological markers
Maria de Fátima Calado Varela Reis
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ESA/108646/2008

Obesidade e síndrome metabólico: do adolescente ao adulto
Elisabete Ramos
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/108695/2008

COMPARISON OF TREATMENT-RELATED DIRECT COSTS FOR DIFFERENT MALIGNANT NEOPLASIA TOPOGRAPHIC GROUPS UNTIL 1 YEAR POST DIAGNOSIS
Filipa Costa
Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE (IPO Lisboa)

PTDC/SAU-ESA/108808/2008

Food related quality of life and nutritional status of Portuguese elderly
Maria Daniel Barbedo Vaz Ferreira de Almeida
Faculdade de Ciências da Nutrição e Alimentação (FCNA/UP)

PTDC/SAU-ESA/108835/2008

Effectiveness of Primary Health Care for the First Phases of the Health Transition (in a group of Portuguese - Speaking African countries)
António Jorge Rodrigues Cabral
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ESA/108914/2008

Ruptured abdominal aortic aneurysm endovascular repair: what effectiveness?
Sérgio Manuel Moreira Sampaio
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ESA/108939/2008

Novel mechanisms of horizontal transfer of integrons in bacteria: implications for the dissemination of antimicrobial resistance clinical settings and environment
Gabriela Conceição Duarte Jorge da Silva
Universidade de Coimbra (UC)

PTDC/SAU-ESA/108960/2008

Sleep disorders in portuguese adolescents. Prevalence and repercussions in local health care planning
Daniel Marques Silva
Instituto Politécnico de Viseu (IPV)

PTDC/SAU-ESA/109021/2008

Environmental reservoirs of antibiotic resistance genes: potential impact in public health
Gabriela Conceição Duarte Jorge da Silva
Universidade de Coimbra (UC)

PTDC/SAU-ESA/109049/2008

A barrier to the spread of tick-borne diseases in Iberia
Alexandra Isabel Sá-Pinto
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ESA/109128/2008

Non-Invasive assessment of endothelial dysfunction in children: characterization of early indicators of increased cardiovascular risk.
Maria de Fátima Ferreira Pinto Fernandes Pereira
Unidade Local de Saúde de São José E.P.E. (ULS)

PTDC/SAU-ESA/109147/2008

Age estimation of living undocumented juvenile suspects from skeletal and dental maturation to determine criminal liability
Hugo Cardoso
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ESA/109172/2008

Risk factors assessment for recurrent oropharyngeal candidiasis in HIV-infected patients: a prospective cohort analysis
Ana Cristina de Almeida Santos Paulo
Universidade do Minho (UM)

PTDC/SAU-MII/098015/2008

Empowering antibiotics by nanoencapsulation
Susana Isabel Fonseca de Almeida Santos Braga
Universidade de Aveiro (UA)

PTDC/SAU-MII/098024/2008

Dissecting the intracelllular traffficking factors involved in M. tuberculosis killing/survival within human macrophages using RNA interference.
ELSA MARIA RIBEIRO DOS SANTOS ANES
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MII/098086/2008

Unraveling the mechanisms of nitrosative stress resistance of Helicobacter pylori: relevance for immune subversion and infectiousness
Marta Sofia Guedes de Campos Justino
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MII/098284/2008

Structural characterization of cellular transcriptional regulator CITED2 and viral latency modulators M2 and ORF73
Colin McVey
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MII/098314/2008

A yeast two-hybrid and yeast three-hybrid approach to study hepatitis delta virus replication
Celso Vladimiro Ferreira de Abreu Cunha
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MII/098362/2008

Human naive CD4 T-cell homeostasis
Ana Espada de Sousa
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/098426/2008

Sialyl Lewis X in dendritic cell migration: role and immunomodulation
Paula Alexandra Quintela Videira
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-MII/098455/2008

GAPDH-based Streptococcus agalactiae experimental vaccine
Paula Ferreira
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-MII/098492/2008

Biosynthesis of the mycobacterial methylglucose lipopolysaccharide. Genetic, biochemical and structural characterization of potential targets for TB therapy
Nuno Empadinhas
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MII/098639/2008

Tipping the balance between T cell regulation and deletion in immune tolerance
Luis Ricardo Silva Graca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/098768/2008

Identification of Plasmodium falciparum drug resistance determinants, especially in relation to components of the Artemisinin Combination Therapy (ACT) - a proteomics approach.
MARIA DE FÁTIMA CARVALHO NOGUEIRA
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MII/098870/2008

Regulatory T cells: from thymus generation to function in target tissues
Carlos Eduardo Tadokoro
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/099118/2008

The influence of bile acids on malaria liver infection
Miguel Prudêncio
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/099186/2008

The role of reactive oxygen species as regulators of B lymphocyte tolerization and memory
Maria Margarida Souto Carneiro
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MII/099239/2008

Role of chromatin structure during antigenic variation in african trypanosomes
Luisa M Figueiredo
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/099314/2008

Gammaherpesvirus latent infection: immunological synapse modulation.
João Pedro Monteiro e Louro Machado de Simas
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/099322/2008

Characterization of the O´nyong nyong virus NSP2 protease: a potential target for putative antiviral therapy.
Ricardo Manuel Soares Parreira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MII/099504/2008

Characterization of Mycobacterium tuberculosis strains of family Lisboa
Isabel Portugal
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MII/099580/2008

Development of essential oils delivery system as a therapeutic option for bacterial vaginosis
Acácio Gonçalves Rodrigues
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MII/099584/2008

Salmonella effector proteins that modulate interactions with host cell membrane trafficking to promote bacterial intracellular replication and virulence
Luís Jaime Gomes Ferreira da Silva Mota
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MII/099591/2008

Role of RabGTPases (Rab8 and Rab35) On Phagocytosis And Phagosomal Maturation Of IgG-Opsonized Heat-killed and Virulent Mycobacterium tuberculosis.
Otília Vieira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MII/099622/2008

TLR2 in the development of protection or pathology during an infection with Mycobacterium tuberculosis: role of the Interleukin-12-family of cytokines
Margarida Saraiva
Universidade do Minho (UM)

PTDC/SAU-MII/099623/2008

Functional analyses of inclusion membrane proteins of Chlamydia trachomatis
Luís Jaime Gomes Ferreira da Silva Mota
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MII/099743/2008

Peripheral generation of Regulatory T cells in Experimental Malaria
Carlos Eduardo Tadokoro
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/099772/2008

Malaria drug-resistance: development of a novel, clinically useful drug-sensitivity assay for Plasmodium species.
Thomas Hänscheid
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/099816/2008

Small immunoactive peptidoglycan (siPGN) derivatives as modulators of bacterial inflammatory host response
Sérgio Joaquim Raposo Filipe
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MII/100009/2008

Listeria monocytogenes post-transcriptomics analysis to decipher the in vivo infectious process
Didier Cabanes
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MII/100016/2008

Role of haematopoietic cell subsets during lymphoid organogenesis
Henrique Veiga Fernandes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/100048/2008

Regulation of KIR expression and function on human CD8+ T cells by interleukin 15
Fernando Aguilar Arosa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MII/100155/2008

Effect on T cell immunity induced by treatment with intravenous polyclonal immunoglobulin
Cristina Maria Godinho Pires João
Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE (IPO Lisboa)

PTDC/SAU-MII/100605/2008

Cellular and molecular control of thymic IL-7 expression in vivo.
Nuno Miguel de Oliveira Lages Alves
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MII/100780/2008

Role of ASF/SF2 and SRp20 in IL-1β secretion
LUÍS FILIPE FERREIRA MOITA
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/100801/2008

Cellular and molecular characterization of the interaction between S. epidermidis biofilms and the host immune system
Nuno Miguel Dias Cerca
Universidade do Minho (UM)

PTDC/SAU-MII/100957/2008

Blockage of anti-atherogenic and anti-inflammatory properties of high density lipoproteins by specific antibodies
José Delgado Alves
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-MII/100964/2008

PneumoSyS - A systems biology approach to the role of pneumococcal carbon metabolism in colonization and invasive disease
Ana Rute Ramos Neves
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MII/100969/2008

Natural Immune tolerance to genetically non-self antigens
Jocelyne Demengeot
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/100994/2008

Contribution of yeast-bacteria interactions to the emergence and evolution of denture-related stomatitis
Célia Sacramento Santos Pais
Universidade do Minho (UM)

PTDC/SAU-MII/101025/2008

The regulatory role of human blood monocytes in inflammation: from molecular mechanisms to potential therapeutic strategies against chronic inflammatory diseases.
Elisabetta Padovan
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/101130/2008

Transcytosis of small domains antibodies through the blood-brain barrier. Targeting small domains antibodies against Dengue virus to the central nervous system
Isa Domingues Serrano
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/101245/2008

Deciphering human regulatory T cell development and differentiation
Iris Caramalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/101321/2008

Acinetobacter and public health: risks posed by community and hospital strains
Paula Cristina Maia Teixeira
Universidade Católica Portuguesa (UCP)

PTDC/SAU-MII/101679/2008

Structural characterisation of NOD2 domain interactions in signal transduction
Maria Arménia Abreu Fonseca de Carvalho Teixeira Carrondo
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MII/102086/2008

Role of CD38 and NAD metabolism in immune regulation and development of autoimmune diseases
Teresa Maria Caldeira Martins
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MII/102134/2008

HCV-specific immune response in hepatitis C chronically infected patients during antiviral therapy: association of HCV-specific CD8 T-cell response and dendritic cells phenotype to the outcome to therapy.
Paula Cristina Santos Luxo Maia
Universidade de Coimbra (UC)

PTDC/SAU-MII/102370/2008

Studies on the Bcn-OmpA protein to develop a serodiagnostic method and a vaccine to prevent infections caused by Burkholderia cepacia complex.
Sílvia Andreia Sousa
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-MII/102560/2008

Helicobacter pylori: molecular mechanisms underlying infection and study of Photodynamic Inactivation as an alternative to eradication.
Mónica Alexandra Roxo Cruz Rosa Iglésias
Universidade Católica Portuguesa (UCP)

PTDC/SAU-MII/102596/2008

Immune stimulation of the mosquito Anopheles gambiae response against the malaria parasite Plasmodium berghei
Henrique Silveira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MII/102619/2008

The role of complement system activation and regulation in patients infected with Plasmodium falciparum
Luís Távora Tavira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MII/102647/2008

Genome-wide screen of multi-drug resistance in malaria parasites using high-throughput genetics and genomics approaches
Pedro Vitor Lemos Cravo
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MII/102689/2008

Design of a therapeutic melanoma vaccine candidate: delivery strategies of a peptide antigen to dendritic cells.
Helena Isabel Fialho Florindo Roque Ferreira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-MII/102691/2008

Molecular mechanisms of amoxicillin resistance in Helicobacter pylori
Mónica Oleastro
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MII/102784/2008

The functionality of bifidobacteria on obese non diabetic individuals
Maria Leonor Faleiro
Universidade do Algarve (UAlg)

PTDC/SAU-MII/102795/2008

Analysis of antibody neutralization specificities and antibody-dependent-cell-mediated virus inhibition in Human Immunodeficiency Virus Type 2 infection.
Nuno Eduardo Moura dos Santos da Costa Taveira
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MII/102880/2008

Role of heme oxygenase-1 (HO-1) in non-neurological severe acute malaria
Elsa Marina Galinho de Seixas da Fonseca
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/102936/2008

Studies on fluid therapy in the light of its influence in local and systemic inflammation, and on ati-inflammatoty drug behavior. The role of drug delivery systems and nanomedicines
Maria Luísa Teixeira de Azevedo Rodrigues Corvo
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-MII/103309/2008

Characterization of two drugs obtained from plants and validation of their efficacy and their association in the treatment of psoriasis
MARIA DO CÉU GONÇALVES DA COSTA
Instituto Nacional de Engenharia, Tecnologia e Inovação (INETI)

PTDC/SAU-MII/103322/2008

Establishment of a mouse model for lupus-like disease that is inducible by disrupted T-cell regulation
Constantin Fesel
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/103425/2008

Acquisition and reversion of antifungal resistance by Candida albicans and Candida parapsilosis: in vitro and in vivo assays
Cidalia Pina Vaz
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MII/103429/2008

Development of a new immunodiagnostic test for giardiasis: detection of IgA secretory against Giardia-specific FABP proteins in saliva of paediatric population
Maria do Céu Rodrigues de Sousa
Universidade de Coimbra (UC)

PTDC/SAU-MII/103457/2008

Elucidating the role of Candida albicans ALS proteins in cell surface variation and adhesion.
Isabel M Miranda
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MII/103656/2008

Receptors Tyrosine Kinase Relevance in HPV-induced cervical lesions
Adhemar Longatto
Universidade do Minho (UM)

PTDC/SAU-MII/103724/2008

Q fever in Portugal. Coxiella burnetii heterogeneity, antimicrobial susceptibility and host genetic immune variation.
Ana Sofia Santos
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-MII/103782/2008

Role of metal ions in virulence of Enterococcus faecalis: adding new pieces to the puzzle
Maria de Fátima Silva Lopes
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-MII/103827/2008

HIV-2 Vif dependent HIV proviral DNA incorporation and activation
Isabel Maria Corrêa Calvente de Barahona
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-MII/103941/2008

Study of inhibitory effect from different Apobec family proteins against HIV-2 Vif
Isabel Maria Corrêa Calvente de Barahona
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-MII/103960/2008

HIV-2 infection: tropism and genetic variability in the env gene
Vítor Manuel Jorge Duque
Hospitais da Universidade de Coimbra, E.P.E (HUC/UC)

PTDC/SAU-MII/104011/2008

Role of chemokine receptors in recovery of T cell subpopulations after lymphopenia.
Afonso Rocha Martins de Almeida
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/104158/2008

Regulation of T cell differentiation and activation by CD27-CD70 receptor-ligand interactions in the thymus and in the periphery
Bruno Miguel de Carvalho Silva Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/104172/2008

Entamoeba histolytica virulence factors: response to oxidative and nitrosative stress
João Filipe Bogalho Vicente
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MII/104223/2008

When inflammation faces resolution: the action of neutrophils on monocyte recruitment.
Angelo Miguel Silva Calado
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/104227/2008

Mechanism and consequences of an IL-8 inducing herpesvirus gene.
Michael Parkhouse
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/104231/2008

The Role of B-glucan in Pneumocystis jirovecii Pneumonia (PcP): A new diagnostic tool.
Olga Maria Guerreiro de Matos
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MII/104251/2008

Filamentous bacteriophages and pathogenecity factors of Neisseria meningitidis, from a collection of invasive strains and isolates from asymptomatic carriers
Mário Manuel do Carmo de Almeida Santos
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-MII/104291/2008

P. falciparum resistomics - the multiple drug transporters involved in malaria drug resistance
Jose Pedro Blanco Panadés Gil
Universidade do Algarve (UAlg)

PTDC/SAU-MII/104350/2008

Biofilms- an advantage for major clonal complexes associated to infections?
Luisa Maria Sobreira Vieira Peixe
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-MII/104351/2008

The role of secretory systems on Legionella pneumophila infection.
António Verissimo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MII/104471/2008

Catecholamines promote Candida efflux pumps: a threat to critical care patients
Cidalia Pina Vaz
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MII/104479/2008

Cronobacter spp. in Neonatal Intensive Care Units in Hospitals of the Algarve and in Powdered Infant Food (Cronobak)
Célia Quintas
Universidade do Algarve (UAlg)

PTDC/SAU-MII/104622/2008

Molecular Dissection of the Intracellular Route of Plasmodium in Macrophages and Dendritic Cells
Duarte Barral
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/104698/2008

The regulation of TELOMERES & TELOMERASE in Immunosenescence
Maria Godinho Alves Vieira Duarte Soares
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/104762/2008

Shistosoma haematobium infection and its role in inflammation and carcinogenesis of bladder epithelial cells.
José Manuel Alves Correia da Costa
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-MII/104931/2008

Role of the tyrosine kinase RET in foetal and adult haematopoiesis
Henrique Veiga Fernandes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/105114/2008

Study of evasion mechanisms to innate immunity in group B streptococcal infections: identification of novel therapeutic targets.
Ilda Maria Barros Santos Gomes Sanches
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-MII/105387/2008

Hepatitis C virus-specific CD8+ T -cell response during pegylated alpha interferon and ribavirin treatment in HCV/HIV-1 coinfected patients: association to the outcome of therapy.
Paula Cristina Santos Luxo Maia
Universidade de Coimbra (UC)

PTDC/SAU-MII/105404/2008

Cross-talk between antibiotic resistance and virulence of Stenotrophomonas maltophilia
Manuela Caniça
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MII/105471/2008

Modulation of invariant Natural Killer T-cell functional differentiation
Marta Sofia Ferreira Monteiro Coelho Antunes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/105536/2008

Heterogeneous use of cellular receptors by HIV-2 and the depletion of CD4+ T-lymphocytes: role of apoptosis and alpha4beta7 integrin interaction - implications on HIV-2 pathogenesis
José Miguel Azevedo Pereira
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MII/105604/2008

ALLOSTEM - Exploring the non-immunogenic potential of Umbilical Cord derived Stem Cells in Regenerative Medicine
Nuno Neves
Universidade do Minho (UM)

PTDC/SAU-MII/105653/2008

Insight into the underlying immune interactions of Rickettsia conorii infection in the arthropod- host- pathogen interface
Rita De Sousa
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-MII/105655/2008

Identification and characterization of genes involved in Drosophila-Wolbachia interactions
Luis Manuel Valla Teixeira
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/105657/2008

The fate of new available antibiotics in biofilms of Coagulase Negative Staphylococci (CNS)
Domingas do Rosario Verissimo Jacinto Tavares de Oliveira
Universidade do Minho (UM)

PTDC/SAU-MII/105718/2008

The role of adenosine in anti-Candida albicans immunity
Teresa Maria Fonseca de Oliveira Gonçalves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MII/108134/2008

CD38, an ectoenzyme with a prominent function in immune regulation: role in tumour immunity
Teresa Maria Caldeira Martins
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MII/108206/2008

Subversion of the host endocytic pathway by Plasmodium sporozoites
Duarte Barral
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MII/108356/2008

Impact of the Emergence of Antiviral Drug Resistance on Influenza A Viruses Evolution
Helena Rebelo-de-Andrade
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MII/108578/2008

Respiratory tract infections & malaria: a new case of mutual interactions?
Maria Manuel Dias da Mota
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MII/108709/2008

Efficacy of anidulafungin and anidulafungin in association with TMP-SMZ in the mice model of Pneumocystis.
Olga Maria Guerreiro de Matos
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MII/108860/2008

RATIONAL IN SILICO SCREENING TOWARD TARGETING NEW ANTIMICROBIAL AGENTS
Maria Natália Dias Soeiro Cordeiro
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/098248/2008

Nanocarriers for topical photodynamic therapy of thick skin tumors
Maria Barbara dos Anjos Figueira Martins
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/098253/2008

Developing strategies to understand antibiotic influx and antimicrobial resistance at a molecular level
Alberta Paula Lobo Machado Gameiro-dos-Santos
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/098470/2008

Evaluation of anti-hypertensive drugs in chronic intermittent eucapnic hypoxia: from an animal model to pharmacoepidemiology
Maria Emilia Carreira Saraiva Monteiro
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-FCF/098733/2008

Lung CYD-DDS (cyclodextrin-based drug delivery systems) for inhalation
Helena Maria Cabral Marques
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/098734/2008

Targeting the mitochondrial electron transport chain of malaria parasites: computer-assisted design and synthesis of bc1 complex inhibitors as antimalarial agents
Rui Moreira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/098769/2008

Advancing in the treatment of breast cancer: combining tumor cell and vascular targeting of liposomal chemotherapy.
João Nuno Sereno de Almeida Moreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/098830/2008

Development of lipid-based systems for siRNA delivery to the central nervous system: novel neuroprotective strategies for acute brain injury.
Maria da Conceição Monteiro Pedroso de Lima
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/098872/2008

Regulation of the ubiquitin-proteasome system by BDNF in hippocampal neurons
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/098911/2008

Coenzyme A (CoA) and AcylCoA a dynamic hub of the mitochondrial dysfunction in drug-induced hepatotoxicity
Margarida Maria Fernandes Baptista e Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/098978/2008

Patophysiologic implications of the eye´s neurohumoral regulation oby ghrelin and associated peptides.
Amandio Rocha Sousa
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FCF/099033/2008

TheraPolymLung - Therapeutic conjugate polymer targeted as specific nanomedicine delivery anticancer agents for non-small lung cancer cells
Bruno Sarmento
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-FCF/099149/2008

Evaluation of the neuroprotective role of Annexin A1 in experimental models of Parkinson's disease
Margarida Casal Ribeiro Castro Caldas Braga
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/099163/2008

Therapeutic Potential of Novel Bile Acid Conjugates in Experimental Parkinson´s Disease
Cecília Maria Pereira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/099214/2008

Translating advances in personalized medicine to Azorean population.
Luisa Maria Quental Mota Vieira
Hospital do Divino Espírito Santo de Ponta Delgada, EPE (HDESPD, EPE)

PTDC/SAU-FCF/099217/2008

The relationship between intestinal epithelial nutrient transport, inflammatory bowel disease and colorectal cancer
Fátima Martel
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FCF/099308/2008

Modulation of autophagy as a novel therapeutic strategy for Machado-Joseph disease
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/099357/2008

Development of nanovectors for targeting and delivery of therapeutics to cancer stem cells (CSC): towards novel therapies against resistant and recurrent breast cancer
Lara Carolina Alvarez de Lacerda
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/099384/2008

Produgs of flavonoids: improving bioavailability through increased solubility
Ana Luisa Ferreira Simplicio
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-FCF/099486/2008

Adenosine, neurotrophic factors and excitability control in the hippocampus
Ana Maria Ferreira Sousa Sebastião
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-FCF/099520/2008

Nanostructured biomimetic interfaces for enzyme studies applications
Jose Luis Fontes da Costa Lima
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/099644/2008

Chemokine receptors antagonists in antiretroviral therapy - effects on viral quasispecies and consequences in the pathogenesis of HIV infection
José Miguel Azevedo Pereira
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-FCF/099680/2008

Inflammation in chronic renal disease as a risk factor for resistance to recombinant human erythropoietin therapy
Alice Santos-Silva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FCF/099902/2008

Biochemistry characterization and pharmacology intervention of the metalloproteinases isolated from Trypanosoma brucei brucei parasites
Marcelo Sousa Silva
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-FCF/099991/2008

Biocalorimetry, Microbiology and peptide synthesis - a cooperative study in the search of effective antimicrobial peptides as new anti-infective agents
Margarida Maria Henriques Mesquita Bastos
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/SAU-FCF/100069/2008

NanoFer: New therapeutic approach to cancer treatment based on magnetite multifunctional nanoparticles
João Paulo Miranda Ribeiro Borges
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FCTUNL/UNL)

PTDC/SAU-FCF/100164/2008

Glycophthalocyanines for therapeutics and imaging
Rosa Cristina S Fernandes
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-FCF/100207/2008

Understanding the role of PINK1 in mitochondrial dysfunction and cell death in cancer and neurodegenerative diseases
Maria Helena Vasconcelos Meehan
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-FCF/100268/2008

DNA Smart Lesions
Maria de Fátima Guerreiro da Silva Campos Raposo
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FCTUNL/UNL)

PTDC/SAU-FCF/100291/2008

EncapsDevice: Development of polymeric nanostructures for nasal and pulmonary delivery of peptides and proteins
Ana Margarida Moutinho Grenha
Universidade do Algarve (UAlg)

PTDC/SAU-FCF/100485/2008

Exploring the impact of ecstasy on retinal physiology: A pioneer study
António Francisco Rosa Gomes Ambrósio
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-FCF/100573/2008

Genomic and phenotypic effects of the combined use of epigenetic-modifying drugs in prostate cancer
Carmen Jerónimo
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-FCF/100641/2008

Cellular Uptake and Selectivity of 99mTc-labeled complexes containing substrates or inhibitors of iNOS (L-Arginine analogues)
Filipa Fernandes Mendes
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-FCF/100761/2008

Endothelin-1 antagonism in primary and secondary experimental pulmonary hypertension: unraveling the mechanisms underlying myocardial effects and potential therapeutic implications
Joaquim Adelino Correia Ferreira Leite Moreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FCF/100762/2008

Pharmacologic use of Gasotransmitters in Severe Malaria.
Miguel Amado Franco Parreira Soares
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-FCF/100764/2008

Development of new anti-inflammatory drugs with flavonoid structure: Evaluation of their effects in pro-inflammatory signalling systems in vitro and in vivo
Eduarda das Graças Rodrigues Fernandes
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/101104/2008

Function of the orexigenic peptide ghrelin in the hippocampus
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/101121/2008

New insights for hormonal-dependent breast and prostate therapy: new drugs and targets
Natércia Aurora Almeida Teixeira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FCF/101124/2008

Neuro-activity of cocaine-opiate combinations
Catarina Oliveira
Universidade de Coimbra (UC)

PTDC/SAU-FCF/101232/2008

APOPTOTIC SIGNALING AS A THERAPEUTIC TARGET IN MELANOMA
Paulo Jorge Gouveia Simoes Da Silva Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/101288/2008

Production and characterization of Neutralizing Human Monoclonal Antibodies targeting the envelope glycoproteins of the Human Immunodeficiency Virus Type 2 (HIV-2)
Helena Barroso
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-FCF/101326/2008

Hydrogen peroxide as an emerging target for the treatment of arterial hypertension: from gene regulation of renin-angiotensin system to salt-water homeostasis
Teresa Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FCF/101339/2008

Integrated Methodologies for the Development of an Anti-Malarial Multistage Particulate Vaccine
António José Leitão das Neves Almeida
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/101450/2008

Selective neuronal vulnerability and modulation of mitochondrial dynamics as pharmacological targets in neurodegeneration
Jorge Miguel de Ascenção Oliveira
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/101496/2008

Plasticity of plasmid-mediated fluoroquinolone resistance in Gram-negative bacteria: discovery and prediction
Manuela Caniça
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-FCF/101613/2008

Mechanisms of regulation of the proteasome under excitotoxic conditions
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/101633/2008

ANTIOXIDANT AND ANTI-INFLAMMATORY HITS FROM MEDICINAL PLANTS
Pedro Jorge Macedo Abreu
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-FCF/101677/2008

Modulation of p53 activity as a strategy on the treatment of cancer and neurodegenerative disorders: searching for new small-molecules
Lucília Helena Ataíde Saraiva
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/101774/2008

Genomic and non-genomic effects of androgens in human arteries
Ignacio Verde
Universidade da Beira Interior (UBI)

PTDC/SAU-FCF/101835/2008

Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction
Paulo Jorge Gouveia Simoes Da Silva Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/101950/2008

A new life for old antimycobacterial drugs: development of prodrugs of pyrazinoic acid activated by mycobacterial esterases as a way to circumvent resistance to pyrazinamide
Luis Filipe Vicente Constantino
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/101990/2008

Adenosine as the first putative mechanism for differential regulation of circulating and renal renin-angiotensin systems: relevance for the treatment of renal injury associated with hypertension
Manuela Morato
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FCF/102105/2008

Tin and other Metal Complexes with Pharmacological Interest
Maria de Fátima Costa Guedes da Silva
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-FCF/102180/2008

Contribution of advanced glycation end products (AGE) and the activation of their receptor (RAGE) to methamphetamine-induced neurotoxicity
Frederico Guilherme de Sousa da Costa Pereira
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-FCF/102304/2008

INNOCARE- InNovative antiNeOplastiC drugs: study of the interAction with biomembRane modEls.
Carla Moutinho
Universidade do Minho (UM)

PTDC/SAU-FCF/102361/2008

Retinoids for psoriasis and cancer: Molecular mechanisms of pharmacological and toxicological effects and combination therapies with antiestrogenic drugs
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/102403/2008

Desenvolvimento de Stents e Grafts Cardiovasculares Inovadores com Libertação Controlada de Fármacos
Hermínio José Cipriano de Sousa
PRODEQ - Associação para o Desenvolvimento da Engenharia Química (PRODEQ)

PTDC/SAU-FCF/102455/2008

Protecting retinal ganglion cells in glaucoma: adenosine receptors as important players?
Ana Raquel Sarabando Santiago
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-FCF/102594/2008

HIV Drug Risk Assessment: A Multidisciplinary Approach to NNRTI-induced Toxicity
Alexandra Maria Moita Antunes
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-FCF/102607/2008

“When bile stops to flow”: depicting pathways of bile acid liver damage in icteric and non-icteric cholestasis in human foetal and adult hepatocytes
Rui Fernando Marques da Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/102614/2008

Structural basis for selectivity in cytochrome P450 enzymes. Lead optimization of new non-steroid CYP19 inhibitors.
Maria Luisa Campeão Fernandes Vaz Sá Melo
Universidade de Coimbra (UC)

PTDC/SAU-FCF/102807/2008

Enhancing the killing of intracellular multi-drug resistant tuberculosis (MDRTB) by human macrophages: a new chemotherapeutic strategy to fight MDRTB.
Miguel Viveiros Bettencourt
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-FCF/102906/2008

Modulation of endogenous ataxin-2 to control pathogenic ataxin-3-induced neurodegeneration: A molecular therapy approach mediated by lentiviral vectors for Machado-Joseph disease
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/103033/2008

Glucosamine effects in cartilage: a proteomic approach
Luísa Barreira
Centro de Ciências do Mar (CCMar)

PTDC/SAU-FCF/103085/2008

A multi-target therapeutic strategy to overcome the selection of resistance to antimalarial drugs and drug-candidates
Maria de Lurdes dos Santos Cristiano
Centro de Ciências do Mar (CCMar)

PTDC/SAU-FCF/103182/2008

Forestry biomass as a source of bioactive compounds
Ana Paula Coelho Duarte
Universidade da Beira Interior (UBI)

PTDC/SAU-FCF/103659/2008

Development of antiretroviral-loaded nanoparticles to be used in the formulation of vaginal microbicides
Maria Fernanda Coelho Guedes Bahia
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FCF/103741/2008

Preliminary and mechanistic apoptosis induction studies of bioactive alkaloids isolated from species of Tabernaemontana genus.
Ana Margarida Monteiro Madureira Fernandes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/103814/2008

Endocannabinoid system in melanocytes: effect of ultraviolet radiation.
Maria Augusta Vieira Coelho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FCF/103826/2008

Anti-diabetic infusions from Portuguese native plants: composition, bio-safety, efficacy and mechanisms of action (Tea4Health)
Celia Maria Miguel Antunes
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/103829/2008

InibHipA - A new weapon to fight persistent bacterial infections
Miguel Xavier Jesus Josefat Fernandes
Universidade da Madeira (UMA)

PTDC/SAU-FCF/103896/2008

Neuroprotective mechanisms of simvastatin in transient focal cerebral ischemia
Bruno Miguel Nogueira Sepodes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/103901/2008

Design of chitosan nanoparticles as adjuvant for oral administration with Hepatitis B vaccine.
Olga Maria Fernandes Borges
Universidade de Coimbra (UC)

PTDC/SAU-FCF/104180/2008

Evading Pgp mediated-efflux chemoresistance using a nanoDDS: a new generation of anticancer systems
Mafalda de Castro Ascensão Marques Videira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/104441/2008

Screening, characterization and mechanisms of natural compounds as antiprotozoan leads or drugs.
Carlos Manuel Freire Cavaleiro
Universidade de Coimbra (UC)

PTDC/SAU-FCF/104469/2008

Pinane derivatives as anti-osteoarthritic agents: structure activity relationship.
Carlos Manuel Freire Cavaleiro
Universidade de Coimbra (UC)

PTDC/SAU-FCF/104500/2008

NanoDiab - Development of Nanotechnology Based Systems for Therapy and Prevention of Diabetes
Bruno Sarmento
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FCF/104605/2008

Cyclic nucleotides compartmentalization: new perspectives to treat hypertension?
Ignacio Verde
Universidade da Beira Interior (UBI)

PTDC/SAU-FCF/104676/2008

Characterization of fluoroquinolone effects on human bone remodelling processes: in vitro studies on osteoblastic and osteoclastic cells, and on co-cultures of osteoblasts and osteoclasts.
João Miguel Silva Costa Rodrigues
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-FCF/104802/2008

Taking an analgesic kyotorphin derivative lead to the edge of clinical trials
Isaura Ferreira Tavares
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FCF/105205/2008

Angiotensin II Receptor Antagonists - Characterization of the metabolic actions in the cardiovascular system.
Helder Jose Marques Pinheiro
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/105279/2008

Fullerene derivatives based on C60-phenolic conjugates: solubilization and investigation of metabolism, permeability, toxicity and biological activity
Vukosava Milic Torres
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-FCF/105291/2008

Predicting Transporter Effects on the Pharmacokinetics of Metabolized Drugs
José Augusto Guimarães Morais
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/105382/2008

Regulation of Na+,K+-ATPase in the ageing kidney: Role of oxidative stress, cardiotonic steroids and hypertension
Patricio Soares-da-Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FCF/105386/2008

Impact of Pharmacogenetics on the Population Pharmacokinetics of Antiretroviral drugs in HIV/HCV and/or HBV co-infected patients
José Augusto Guimarães Morais
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FCF/105467/2008

Control by caffeine and adenosine receptors of stress-induced neuronal plasticity in the hippocampus and amygdala
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/105617/2008

Efficacy of gliptins monotherapy or under metformin association for type 2 diabetes management - Experimental evaluation of the best stage to start therapy
Flávio Nelson Fernandes Reis
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-FCF/105660/2008

Bladder cancer - Pharmacological prevention and clinical, pathological and cytogenetic prognostic markers
Frederico Jose Teixeira
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-FCF/105667/2008

The neurobiology of anxiety: the amygdala and bed nucleus of the stria terminalis as targets of anxiolytic drugs
JOSÉ MIGUEL GOMES MOREIRA PÊGO
Universidade do Minho (UM)

PTDC/SAU-FCF/108034/2008

AMPAkines and excitatory stimulation increase proliferation, differentiation and maturation of neurons in the main neurogenic niches of the postnatal mouse brain
Joao Jose Oliveira Malva
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/108092/2008

Preclinical assessment of the potential for significant interactions between herbal extracts used in programs of body weight reduction and conventional drugs
Amílcar Celta Falcão Ramos Ferreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/108172/2008

Novel therapy of pancreatic cancer by using gemcitabine-loaded nanosystem
Ana Catarina Beco Pinto Reis
COFAC, Cooperativa de Formação e Animação Cultural, CRL (COFAC)

PTDC/SAU-FCF/108235/2008

Combined effect of anti-cancer drugs on different intracellular targets - A new therapeutic approach in prostate cancer?
Anabela Mota Pinto
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-FCF/108277/2008

NaNoSustain - Multi-functional dendrimeric macromolecules with applications in early diagnosis and treatment of smooth muscle diseases
Joao Filipe Colardelle da Luz Mano
Universidade do Minho (UM)

PTDC/SAU-FCF/108398/2008

Selective therapeutic targets in cerebral global ischemia: the molecular links coupling Ca2+-permeable AMPA receptors to excitotoxic signalling pathways
Armanda Emanuela Castro e Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/108451/2008

PET and SPECT for breast cancer molecular imaging: Y1 receptor targeting with 18F/99mTc-labeled neuropeptide Y analogs
Paula Dolores Galhofas Raposinho
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-FCF/108539/2008

MITOX - Targeting antioxidants to mitochondria: a new therapeutic approach on neurodegenerative diseases
Nuno Milhazes
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FCF/108640/2008

PhageLUTI - Bacteriophages as alternatives to antibiotics in controlling lower urinary tract infections
Joana Cecília Valente Rodrigues Azeredo
Universidade do Minho (UM)

PTDC/SAU-FCF/108738/2008

Towards the efficacy and safety of hypoglycaemic submicron particles delivered by the oral route
FRANCISCO JOSÉ DE BAPTISTA VEIGA
Universidade de Coimbra (UC)

PTDC/SAU-FCF/109102/2008

Novel nanoparticulate systems for physiological insulin delivery: role for the oral route
FRANCISCO JOSÉ DE BAPTISTA VEIGA
Universidade de Coimbra (UC)

PTDC/SAU-OBD/098208/2008

DEVELOPMENT OF A FOLLOW-UP AND RADIOBIOLOGICAL RESEARCH PROGRAM
Brígida Costa Ferreira
Universidade de Aveiro (UA)

PTDC/SAU-OBD/098502/2008

TCR/CD3-associated antigens in normal T cell development and leukemogenesis, and as potential therapeutic targets
Mafalda Maria dos Santos Pinto
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OBD/098642/2008

CDX2-induced alterations of the gastric glycoproteome. Potential clinical applications.
Raquel Maria da Silva Graça Almeida
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OBD/098711/2008

Mitosis and protein N-terminal acetylation.
Rui Gonçalo Viegas Russo da Conceição Martinho
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/098759/2008

Proliferation versus differentiation decisions in nerve cells: exploring the role of multidrug resistance protein 1 (Mrp1) and its modulation in brain tumors
Ana Sofia Iria Azeredo Falcão de Jesus
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-OBD/098953/2008

Molecular mechanisms of Galectin-3 and Sialiltransferases modulating anti-tumoral immunity - New targets for therapeutic applications
Emerson Soares Bernardes
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OBD/099068/2008

High-resolution PET imaging of intratumoral heterogeneity in a cancer stem cell-based animal model of osteosarcoma
Célia Maria Freitas Gomes
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/099164/2008

Understanding the Role of p63 and Tauroursodeoxycholic Acid in Neural Development
Cecília Maria Pereira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-OBD/099254/2008

Underlying mechanisms of the Placenta-Heart Axis: Implications for Congenital Heart Defects
Tiago Alexandre Henriques Coelho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OBD/099270/2008

BRAF oncogenic addiction in human cancers. Uncovering novel oncogenic signaling properties
Ana Paula Soares Dias Ferreira
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OBD/099380/2008

Low doses of ionizing radiation induce a pro-angiogenic response on the vasculature.
Susana Constantino Rosa Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OBD/099382/2008

Tumoral biomarkers - new approach for identification and clinical diagnosis
Elvira Maria Mendes Sardão Monteiro Gaspar
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-OBD/099473/2008

Macrophages and cancer cell invasion: the underlying molecular mechanisms
Maria José Cardoso Oliveira
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-OBD/099701/2008

Role of the transcription factor Cited2 in embryonic stem cell differentiation processes
José Bragança
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-OBD/099714/2008

Implications of Claspin mutations in the maintenance of cell homeostasis, oncogenesis and response to chemotherapy
Teresa Maria Caldeira Martins
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OBD/099753/2008

Nature and function of ultradian cycles of HES1 gene expression in brain tumors
Isabel Maria Mestre Marques Palmeirim
Universidade do Minho (UM)

PTDC/SAU-OBD/099758/2008

Molecular parallelisms in vertebrate somitogenesis and limb development
Isabel Maria Mestre Marques Palmeirim
Universidade do Algarve (UAlg)

PTDC/SAU-OBD/099805/2008

Evaluation of the risk of secondary radiation induced malignancies due to the application of Intensive Modulated Radiation Treatment.
GRISEL MARGARITA MORA PAULA
Fundação da Universidade de Lisboa (FUL/ULisboa)

PTDC/SAU-OBD/099870/2008

Modulation of HRAS alternative splicing and oncogenic activity; role of the 81T/C polymorphism
Patricia Manuel Costa e Castro
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OBD/100001/2008

The Role of ERG1 (Kv11.1) Potassium Channel in Vertebrate Limb Induction and Outgrowth
Ana Catarina Certal
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/100079/2008

Role of protein kinase WNK2 as a tumour suppressor gene in malignant gliomas
Peter Jordan
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-OBD/100199/2008

Dynamic Analysis of Wound Healing Morphogenesis in Zebrafish
Ana Cristina Ribeiro Borges
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/100200/2008

The role of reinnervation in tissue regeneration
António Alfredo Coelho Jacinto
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OBD/100202/2008

Uncover the importance of cilia as signaling structures during regeneration
Maria Leonor Tavares Saúde
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OBD/100213/2008

Volatile biomarkers in the exhaled air: Application to diagnosis, prognosis and therapeutic efficacy of renal cell carcinoma
Paula Guedes de Pinho
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-OBD/100398/2008

Cellular Kinetics and colorectal carcinogenesis: comparative study between right and left colon
PEDRO MANUEL NARRA DE FIGUEIREDO
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/100664/2008

The dialetics of "Stemness": from biology to mathematics
Domingos Manuel Pinto Henrique
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OBD/100870/2008

Investigating the mechanical mechanisms mediated by the actin cytoskeleton that modulate Hippo-dependent cell proliferation.
Florence Janody
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/100939/2008

The role of CHEP12, a novel gene coding for a Calcium-binding EGF-like domain protein in the process of heart induction and organogenesis.
José António Henriques de Conde Belo
Universidade do Algarve (UAlg)

PTDC/SAU-OBD/100947/2008

Establishing the Retinome: the genetic regulatory network of the early Drosophila eye.
Luis Fernando Casares Fernandez
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OBD/101217/2008

Characterization of the pathophysiological role of the Thomsen Friedenreich-related antigens in bladder cancer
Paula Alexandra Quintela Videira
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OBD/101259/2008

Function of Integrins in Drosophila Haemocyte Migration
Soren Prag
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OBD/101263/2008

Human colorectal carcinogenesis and JC polyomavirus T-antigen-dependent insulin receptor substrate 1 nuclear accumulation in biopsies and some prophylatic and/or curative modulator mechanisms involved in the accumulation in cell lines
Luis Almeida
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/101318/2008

Identifying candidate biomarkers for targeted/individualized lung cancer chemotherapy - Phase I.
Odete A B da Cruz e Silva
Universidade de Aveiro (UA)

PTDC/SAU-OBD/101331/2008

MUC1 protein - a new approach to target oncogenic signaling in pancreatic cancer stem cells
Luis Filipe Santos Silva
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OBD/102122/2008

Analysis of microRNAs expression signature in glioblastoma; is it possible to use microRNAs as prognostic factors and therapeutics targets?
Durval C Costa
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OBD/102182/2008

STEAP1 and breast cancer: a therapeutic target or a target to eliminate?
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/SAU-OBD/102674/2008

OncoNet - Protein network-based classification of triple-negative breast cancer
José Bartholo Pereira Leal
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/102738/2008

Identification of the role of calpains in glioma cell proliferation and migration: a potential therapeutic target?
Inês Maria Pombinho de Araújo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OBD/102808/2008

Radioproteomics - Predictive assay of radiation therapy in head and neck and uterine cervical cancers.
Margarida Maria Martins de Abreu Roldão
Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE (IPO Lisboa)

PTDC/SAU-OBD/103029/2008

Role of regucalcin in prostate physiology: effect in calcium homeostasis, cell proliferation and apoptosis
Cláudio Jorge Maia Baptista
Universidade da Beira Interior (UBI)

PTDC/SAU-OBD/103146/2008

New Porphyrin Bioconjugates for Cancer Therapy
Maria Filomena Rabaça Roque Botelho
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/103235/2008

Fighting cancer with a novel cellular and molecular multitargeting approach
João Nuno Sereno de Almeida Moreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OBD/103263/2008

Molecular strategies for ligand-directed combinatorial therapy and drug targeting in breast carcinoma cancer stem cells (CSCs)
Rogério Paulo Pinto de Sá Gaspar
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-OBD/103336/2008

INFLUENCE OF THYMIC STROMAL CELLS AND CHEMOKINE SIGNALING IN ACUTE T-CELL LEUKEMIA DEVELOPMENT
Nuno Alexandre Pinto Rodrigues dos Santos
Universidade do Algarve (UAlg)

PTDC/SAU-OBD/103345/2008

The prevalence of Borrelia infections in cutaneous B cell lymphomas in Portugal
António Medina de Almeida
Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE (IPO Lisboa)

PTDC/SAU-OBD/103519/2008

Alterations in tumour metabolism underlying sensitivity or resistance to therapy with histone deacetylase (HDAC) inhibitors
Jacinta Serpa
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/103589/2008

Molecular and cellular adaptations in renal tubular tissue regeneration
Patricio Soares-da-Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OBD/103613/2008

A Novel Approach for Tracing Cells Into Organs and the Forces that Shape the Embryo
Gabriel José Gonçalves Martins
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-OBD/103675/2008

Downstream target genes of the ETS fusion oncogenes in prostate cancer: functional assays and clinical applications
Manuel António Rodrigues Teixeira
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-OBD/103771/2008

Changing extracellular matrix networks as regulators of transitions between epithelial and mesenchymal fates during embryogenesis.
Solveig Thorsteinsdottir
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-OBD/103973/2008

Functional role of KIT GNNK+ and GNNK- isoforms in glioblastomas
RUI MANUEL VIEIRA REIS
Universidade do Minho (UM)

PTDC/SAU-OBD/103981/2008

Investigation of a new signalling pathway linking deltaD to ciliogenesis and its impact on left-right development
Susana Santos Lopes
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OBD/104037/2008

Searching for modulators and markers of radioresistance in lung cancer: a role for proliferation and apoptosis-associated microRNAS
Henriqueta Alexandra Mendes Brêda Lobo Coimbra Silva
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/104399/2008

Developmental role of the IRE1/Xbp1 signaling pathway during photoreceptor differentiation in Drosophila melanogaster
Pedro Manuel Dias Neto Domingos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-OBD/104410/2008

Molecular characterization of myelodysplastic syndromes - prognostic and therapeutic implications
Ana Bela Sarmento Ribeiro
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/104522/2008

Studies of chromatid cohesion during meiosis in Drosophila melanogaster reveal a novel DNA damage checkpoint pathway essential for oocyte polarity.
Vítor José de Sousa Barbosa
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/104592/2008

Assessment of growth, apoptosis and tumoral necrosis factors in uterine leiomyomas
Miguel de Oliveira Correia
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OBD/104816/2008

Cell-intrinsic and microenvironmental signals intertwined: novel targets for therapeutic intervention in acute lymphoblastic leukemia?
João Pedro Taborda Barata
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OBD/104851/2008

Metastatic Potential Promoted by miRNAs in Adenocarcinoma and Squamous Cell Carcinoma of the Lung
Lina Maria Rodrigues Carvalho
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/105210/2008

Pancreatic Adenocarcinoma - New Therapeutic Approaches
Anabela Mota Pinto
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/105234/2008

Role of Mob1 and Unc119 proteins in cytokinesis and tumorogenesis.
ÁLVARO AUGUSTO MARQUES TAVARES
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/105409/2008

Functional and clinical relevance of ETS transcription factors overexpression associated with chromosome rearrangements in breast cancer
Manuel António Rodrigues Teixeira
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-OBD/105616/2008

Cellular and Developmental Mechanisms Controlling Centrosome Number
Monica Bettencourt Carvalho Dias
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OBD/105710/2008

Zebrafish as an in vivo biomedical model to study vertebral bone fusion - ZeFusion
Leonor Cancela
Centro de Ciências do Mar (CCMar)

PTDC/SAU-OBD/108061/2008

Proteomics of squamous-cell carcinoma of the Head and Neck
Francisco Amado
Universidade de Aveiro (UA)

PTDC/SAU-OBD/108102/2008

Exploring the role of Regulatory T-cells in Cutaneous T-Cell Lymphomas
MARGARIDA LIMA
Centro Hospitalar Universitário do Porto (CHP/MS)

PTDC/SAU-OBD/108285/2008

Mapping of phospho-ERK5 interactome and gene expression profiling in mitosis using proteomics
Sukalyan Chatterjee
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OBD/108313/2008

Endometrial cancer: tumor cell characterization, serum proteomic profile and implications in metastatic spread in vivo
Carlos Manuel Domingues Freire de Oliveira
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/108344/2008

GENETIC SUSCEPTIBILITY TO METASTATIC BREAST CANCER
Jorge Francisco Dias Rodrigues Gaspar
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OBD/108470/2008

Functional and Clinical Relevance of HOXA9 in Human Glioblastoma
RUI MANUEL VIEIRA REIS
Universidade do Minho (UM)

PTDC/SAU-OBD/108604/2008

Immunoinflammatory profile of breast cancer patients
Henriqueta Alexandra Mendes Brêda Lobo Coimbra Silva
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OBD/108608/2008

Multi-Functional Bone Seeking Agents for the Treatment of Skeletal Metastatic Disease
Isabel da Graça Rego dos Santos
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-OBD/108787/2008

OAS1 and breast cancer: looking for a connection.
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/SAU-GMG/098103/2008

Molecular pathogenesis of chromosome translocation associated-congenital anomalies
Dezso David
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-GMG/098274/2008

Intermediates states: At the crossroads of pathways to folding and pathways to disease
Patrícia Ferreira Neves Faísca
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/098386/2008

Study of the CAG repeat instability and clinical variability in Machado-Joseph disease through the analysis of its mutational origins
Sandra Martins
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-GMG/098398/2008

Classical galactosemia: genotype-phenotype correlation and potential modulation of GALT enzyme activity
Isabel Maria Antolin Martins-de-Carvalho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/098698/2008

Influence of genetic and acquired factors on serum bilirubin levels in Gilbert Syndrome patients and normal subjects
Elsa Maria Ribeiro Bronze da Rocha
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/098804/2008

Analysis of the intranuclear life of a nonsense transcript
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/098815/2008

How mRNA translation inhibits nonsense-mediated decay in transcripts carrying an AUG-proximal termination codon
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/098937/2008

BEDGET: deciphering BEhçet's Disease GEneTics
Ana Sofia Simões Domingues de Almeida Oliveira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/099162/2008

Understanding microRNA Profiles and Cellular Functions in Colorectal Cancer
Cecília Maria Pereira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/099266/2008

Migraine and Cluster Headache - clinical, ethiopathogenic and genetic study
José Maria Pereira Monteiro
Centro de Estudos de Cefaleias (CEC)

PTDC/SAU-GMG/099289/2008

Novel gene therapy approach for the treatment of ocular neovascularization
Gabriela Araújo da Silva
Universidade do Algarve (UAlg)

PTDC/SAU-GMG/099355/2008

Study of the role of lysosomal acid ceramidase in lipid-glycosphingolipid cell compartmentalization and its implication for Farber disease pathophysiology
Maria Gil Roseira Ribeiro
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-GMG/099427/2008

Gene identification for autism - follow up to a Genome Wide Association Study
Astrid Vicente
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-GMG/099590/2008

Noncoding RNAs as novel players in the study of complex neurodegenerative diseases
Madalena Cristina da Rocha Martins
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/099615/2008

Phenotype-genotype correlation studies in Essential Tremor: from genes to molecular mechanisms
Gabriel Miltenberger-Miltenyi
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/099655/2008

Renal tubular dysgenesis associated with ACE misfolding: the molecular effects of the new ACE mutation - Q1069R
Tiago Outeiro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/099839/2008

Molecular-clinical studies in Portuguese patients with Lujan-Fryns and Opitz-Kaveggia syndromes: role of MED12 genetic variants in pathophysiological mechanisms
Paula Maria Vieira Jorge
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-GMG/099841/2008

Molecular etiology of congenital hypothyroidism: clinical detail, DNA variants and mutation databases
Paula Maria Vieira Jorge
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-GMG/100206/2008

Clinical, genetic and molecular study of the agenesis of maxillary lateral incisors
Teresa Pinho
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/100313/2008

Unravelling the secrets of Plasmodium liver stage: a multi-directional approach
Maria Manuel Dias da Mota
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/100334/2008

Mutant hybrid forms of phenylalanine hydroxylase: contribution of subunit interactions in the outcome of a human misfolding disorder
Ana Paula Costa Santos Peralta Leandro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/100380/2008

Molecular genetic characterization and correlation with phenotypic risk factors of Portuguese patients with primary open-angle glaucoma (POAG) and juvenile open-angle glaucoma (JOAG)
Maria do Rosário Pires Maia Neves de Almeida
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-GMG/100529/2008

Role of miRNAs as a key regulatory factors in cellular aging
Francisco Javier Enguita
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/100842/2008

Molecular pathology in Duchenne Muscular Dystrophy (DMD) patients: towards personalized therapy
Elsa Maria Ribeiro Bronze da Rocha
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/101048/2008

Bridging the gap between protein methylation and homocysteine: potential role in homocysteine-related vascular disease.
Maria Rita M A Azevedo e Castro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/101057/2008

Identification of a susceptibility locus for gastric cancer in the IL1 gene cluster region
José Carlos Lemos Machado
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-GMG/101209/2008

Molecular Mechanism in Hypertrophic Cardiomyopathy: a new step for the essential identification of genotype-phenotype correlations
Alexandra R Fernandes
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-GMG/101269/2008

A genomic radar screen on mitonuclear communication
Laura Ferreira Teixeira Vilarinho
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-GMG/101436/2008

RNAi SCREEN FOR HOST MOTOR PROTEINS REQUIRED FOR Fc-MEDIATED PHAGOCYTOSIS, SALMONELLA INVASION AND BACTERIAL KILLING
Otília Vieira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-GMG/101537/2008

Genetics of Nonsyndromic Cleft Lip and Palate (NSCLP)
António Alfredo Coelho Jacinto
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/101578/2008

A systems biology approach to human aging
Maria Carmo-Fonseca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/101874/2008

Novel genes causing Familial Hypercholesterolaemia
Mafalda Bourbon
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-GMG/101890/2008

Study of heart formation at molecular terms to understand congenital heart malformations
José António Henriques de Conde Belo
Universidade do Algarve (UAlg)

PTDC/SAU-GMG/101912/2008

RNA binding proteins and cell proliferation - unravelling post-transcriptional regulatory networks
Margarida Henriques da Gama Carvalho
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/102153/2008

An integrated approach to Charcot-Marie-Tooth disease: the first Portuguese cohort for clinical and genetic studies
Gabriel Miltenberger-Miltenyi
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/102404/2008

Regulation of CFTR retention at the plasma membrane by WNK kinase-mediated modulation of Rho GTPase activity
Paulo Henrique Carrasquinho de Matos
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/102561/2008

Criminal behaviour: screening candidate genes
Alda Maria Abreu Cardoso
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/102566/2008

Screening tagSNPs in genes of exocytotic machinery in alcoholism
Alda Maria Abreu Cardoso
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/102572/2008

Candidate genes from gabaergic and glutamatergic system in the etiology of suicide
Alda Maria Abreu Cardoso
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/102591/2008

g-Portugal
Luís Tiago Ferreira Romero Magalhaes
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-GMG/102671/2008

Establishing Drosophila melanogaster as a functional and predictive model for genetic disorders of fatty acid metabolism.
Rui Gonçalo Viegas Russo da Conceição Martinho
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-GMG/102740/2008

Deregulation of TLR9 expression in increased susceptibility to hematological malignancies: The role of T-1237C and IL-6 signaling.
Fernando José dos Santos Rodrigues
Universidade do Minho (UM)

PTDC/SAU-GMG/102889/2008

The sorting and trafficking of lysosomal proteins through M6P independent pathways: molecular, biochemical and functional studies
Sandra Catarina da Conceição Alves
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-GMG/103307/2008

Role of the iron metabolism on the progression of hepatitis C viral infection and treatment response
Maria Fátima Soares Silveira Serejo Leal da Silva
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/103376/2008

Posttranscriptional control of hemojuvelin gene expression and its role in iron homeostasis.
Ana Luísa Silva
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/103562/2008

Identification of Novel Genomic Regions associated with MAC (Microphthalmia, Anophthalmia and Coloboma)
ISABEL MARIA MARQUES CARREIRA
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/103711/2008

Searching for novel genes involved in endometrial oncogenesis
Maria Margarida Ferreira Alves
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/103738/2008

Transcriptional control of house-keeping genes by histone acetylation and Sp1: molecular mechanisms and therapeutic potential
António Medina de Almeida
Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE (IPO Lisboa)

PTDC/SAU-GMG/104392/2008

Non coding RNA in malaria parasites
Celine Carret
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/104395/2008

Development of an integrative knowledgebase for medical systems biology
Matthias Erwin Futschik
Universidade do Algarve (UAlg)

PTDC/SAU-GMG/104694/2008

Modulation of Pyruvate Dehydrogenase Complex: chaperones on the road to novel therapeutic interventions
Maria Isabel Ginestal Tavares Almeida
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/104781/2008

Genetic profiling of high grade glioma tumor resistance to temozolomide: insight from 3D model cultures
Joana Paiva Gomes Miranda
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/104876/2008

Hematopoietic CD34+CD38- progenitor cells in Chronic Myeloid Leukemia - genomic evolution for disease progression
José Rueff
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/104922/2008

Deciphering the erythropoietic (de)control of iron metabolism in thalassemias
MARIA PAULA DUARTE FAUSTINO GONÇALVES
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-GMG/105175/2008

Functional genomics studies of phagocytosis in retinal pigment epithelium
Jose Silva Ramalho
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/105262/2008

Mechanism of action of GATA family transcription factors in the transcriptional regulation of PIGM
António Medina de Almeida
Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE (IPO Lisboa)

PTDC/SAU-GMG/105351/2008

Micro-RNAs and Target Proteins: Key Players in Hepatocarcinogenesis associated with Chronic Viral Hepatitis
Deborah Penque
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/105565/2008

Investigation of anaesthetics' effects on the mitochondrial respiratory chain system in human hepatocytes - pharmacogenomics approach and evaluation of clinical implications
Manuela Grazina
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/107930/2008

Candidate genes in Ankylosing Spondylitis and its repercussion in clinical practice
Jaime Branco
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/108049/2008

Genetic factors in stroke risk, recovery and response to tissue plasminogen activator (tPA) therapy
Astrid Vicente
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-OSM/098102/2008

Direct and indirect mechanisms of hepatic injury by high-fructose diets
John Griffith Jones
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/098141/2008

Hippocampal metabolic abnormalities in early Alzheimer's disease
Rui de Albuquerque Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/098221/2008

The future of fatty livers in surgery and transplantation: is preconditioning and mitochondrial tolerance a useful strategy to overcome ischemia/reperfusion injury?
Carlos Palmeira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/098296/2008

Obesity in peritoneal dialysis uremic patients: relationship with peritoneal membrane status and peritoneal dialysis prescription
Anabela Rodrigues
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-OSM/098315/2008

The role of regucalcin in spermatogenesis: regulation of calcium homeostasis and apoptosis?
Sílvia Cristina da Cruz Marques Socorro
Universidade da Beira Interior (UBI)

PTDC/SAU-OSM/098569/2008

Molecular mechanisms of insulin resistance after immunosuppressive therapy
EUGÉNIA MARIA LOURENÇO DE CARVALHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/098648/2008

Immune surveillance of iron homeostasis: is hepcidin the key?
Idílio Jorge Matias Pereira Pinto
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OSM/098722/2008

Caracterização do mecanismo pelo qual células mesenquimatosas induzem remielinização.
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OSM/098905/2008

Remodeling of gut - adipocyte - beta-cell communication in type 2 diabetes after bariatric surgery
Raquel Maria Fino Seiça
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OSM/099013/2008

BIOMER - Biomarkers of endothelial dysfunction after coronary stent implantation
Maria Teresa Ferreira Marques Pinheiro
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-OSM/099110/2008

The role of microRNAs in the control of the human hepcidin gene expression and their involvement on iron metabolism regulation
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-OSM/099349/2008

Fanconi Anemia: a multidisciplinary investigation for prevention against chromosome instability and cancer development
Maria Beatriz Beça Gonçalves Porto e Vasconcelos
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-OSM/099514/2008

Role of Long-chain Fatty Acid Metabolites on Mitochondrial Dysfunction: Implications on Energy Metabolism and Cell-death
Maria de Fátima Vieira Ventura
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-OSM/099555/2008

Parasympathetic dysfunction and insulin resistance: a translational study.
Maria Paula Borges de Lemos Macedo
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OSM/099611/2008

Diabetes-induced Alzheimer-like changes at the supraspinal pain control system: a contributing factor for diabetic neuropathy?
Isaura Ferreira Tavares
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/099632/2008

3D in vitro models for reducing animal experimentation in pharmaceutical development: integrative approaches for prediction of hepatic drug metabolism and neurotoxicity
Paula Marques Alves
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-OSM/099663/2008

ZEBRAPARK: Zebrafish (Danio rerio) as a novel in vivo model for understanding Parkinson´s disease pathology
Ana Dulce de Ascensao Almeida Correia
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OSM/099724/2008

Relevance of Cholesterol - rich diet on protection from experimental cerebral malaria
Ana Maria de Amarante Pamplona Dias dos Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OSM/099726/2008

The role of PP1/Tctex1d4 complex in sperm physiology and TGFbeta signalling
Margarida Fardilha
Universidade de Aveiro (UA)

PTDC/SAU-OSM/100029/2008

New challenges in the approach to human blood-brain barrier pattern as a function of time course, regional specificity and cellular interplay
Maria Alexandra de Oliveira Silva Braga Pedreira de Brito
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-OSM/100062/2008

Influence of chronic exposure to opioid drugs in energy homeostasis- impact of nutrition in the treatment of drug addiction
MARIA TERESA MARTINS DA CUNHA OLIVEIRA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/100105/2008

TTR amyloid fiber formation in vivo - beyond genetic factors
Goncalo martins Conde da Costa
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-OSM/100113/2008

Peripheral effects of melanocortins on energy homeostasis: role of melanocortin 5 receptor
Alexandra Maria Monteiro Gouveia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/100126/2008

Effects of persistent organic pollutants (POPs) on adipocyte biology: putative involvement in the metabolic syndrome
Maria Conceicao Costa Pinho Calhau
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/100127/2008

UNRAVELING THE RELATIONSHIP BETWEEN INFLAMMATION, IRON AND LIPID METABOLISM IN ATHEROGENESIS
LUCIANA MARIA GONÇALVES DA COSTA
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-OSM/100135/2008

Synaptic Dysfunction in a Mouse Model of Machado Joseph Disease
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/100179/2008

Salivary glands guanylin and natriuretic peptides systems in chronic kidney diseases.
Benedita Sampaio Maia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/100267/2008

The perfusion in microcirculation of the gastric fundus in guinea pigs after proximal division of the short gastric vessels and complete fundoplication
José Luis Costa Guedes daSilva
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OSM/100306/2008

A new animal model for age-related macular degeneration
Paulo Pereira
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OSM/100353/2008

Unravelling the effect of nutrionally-defined diets on progression of vascular disease in chronological aging. The role of sirtuins.
Delminda Gamelas Neves Lopes de Magalhaes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/100408/2008

A combined microRNAome and metabolomic methodology for diagnosis and prognosis of prostate cancer
Maria Carmen Alpoim
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/100473/2008

Role of carotid body in metabolic disturbances: mechanistic and therapeutic approach
SÍLVIA MARGARIDA VILARES SANTOS CONDE
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OSM/100475/2008

Heart failure regulation by Wnt signaling
Sonia Alexandra Vieira e Pinho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/100533/2008

Fabry disease: crosstalk between clinic, genetic and immunologic features
Maria de Fátima Matos Almeida Henriques de Macedo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OSM/100540/2008

Why can't osteoarthritic chondrocytes adjust to hyperglycemia? Glucose sensing, transport and metabolism in normal and osteoarthritic chondrocytes under hyperglycemia
Alexandrina Maria Ferreira dos Santos Pinto Mendes
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/100674/2008

Contribution of membrane cholesterol-disrupting properties of aluminium to its neurotoxic action
Virgília Sofia Almeida de Azevedo e Silva
Universidade de Aveiro (UA)

PTDC/SAU-OSM/100878/2008

Prevalence and severity of fatty liver in morbid obesity: correlation and mechanisms related with the role of ectopic fat in insulin resistance
Helena Cortez-Pinto
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OSM/100936/2008

The role of mitochondrial dysfunction in the aquisition of the glycolytic metabolism (Warburg Effect) of tumour cells
Valdemar de Jesus Conde Máximo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OSM/100949/2008

Nutrition human intervention studies of high antioxidant berries. Effect on the human peripheral blood mononuclear cell proteome
Maria Cláudia Nunes dos Santos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-OSM/101026/2008

Role of pattern recognition receptors (PPRs) in regulation of sodium transport in epithelial intestinal cells
Fernando José Magro Dias
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/101125/2008

The endocannabinoid system and placenta: the effect of cannabis exposure
Natércia Aurora Almeida Teixeira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OSM/101195/2008

Identification and study of a serum nucleator protein capable of bone and arteries (re)mineralization.
Dina Costa Simes
Centro de Ciências do Mar (CCMar)

PTDC/SAU-OSM/101298/2008

Eventos pos-translacionais na protecção do stress oxidativo
Maria João Gameiro de Mascarenhas Saraiva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OSM/101322/2008

Determination of metabolic, structural and biomechanical bone factors that explain osteoporotic fracture risk: identification of a fracture risk cut-off with diagnostic and therapeutic applications
Helena Canhão
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OSM/101376/2008

TOXICOPROTEOMICS:IDENTIFICATION OF PROTEIN TARGETS TO ELUCIDATE THE MOLECULAR MECHANISMS OF METHYLMERCURY TOXICITY
Cristina Maria Leitão de Carvalho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-OSM/101386/2008

The application of 2D-DIGE proteomics to the study of human osteoarthritis: A new approach for the identification of osteoarthritis biomarkers.
Dina Costa Simes
Centro de Ciências do Mar (CCMar)

PTDC/SAU-OSM/101412/2008

Cardiac and Skeletal Muscle Mitochondrial Dysfunction in Animal Models of Obesity and Diabetes: Role of the Permeability Transition, Apoptosis and Autophagy and Prevention by the Alkaloid Berberine
Paulo Jorge Gouveia Simoes Da Silva Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/101426/2008

A biophysical approach to the role of diet-manipulated mitochondrial membrane lipid composition on drug-induced hepatic mitochondrionopathy
Paulo Jorge Gouveia Simoes Da Silva Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/101523/2008

Signaling pathways of orexigenic and anorexigenic peptides in Alzheimer´s disease
Cláudia Maria Fragão Pereira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/101658/2008

ONCOLACT - Application of new tools to study the mechanisms underlying health benefits of lactoferrin
LIGIA RAQUEL MARONA RODRIGUES
Universidade do Minho (UM)

PTDC/SAU-OSM/101660/2008

Catecholamine handling by adrenomedullary and immune cells in obesity
Laura Virgínia Pereira Teixeira Ribeiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/101786/2008

Red cell enzymopathies - effects on malaria infection
Ana Paula Martins dos Reis Arez
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-OSM/101847/2008

Ex-vivo Expansion of Human Mesenchymal Stem Cells for Cellular Therapy
Cláudia Alexandra Martins Lobato da Silva
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-OSM/101857/2008

From Human Proteomics to Development of Therapeutic Targets for Lung Hypoplasia
Jorge Manuel Nunes Correia Pinto
Universidade do Minho (UM)

PTDC/SAU-OSM/101952/2008

Intra-adrenal cellular interactions: adipocytes and progenitor cells as new players in human adrenal gland regulation
CLÁUDIA MARGARIDA GONÇALVES CAVADAS
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/102099/2008

Exploring New Roles for Endogenous Bile Acids and microRNAs in Modulating Liver Regeneration
Rui E Castro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-OSM/102305/2008

Exercise and Diabetes Mellitus: Does physical exercise ameliorates mitochondrial abnormalities in diabetic tissues? Special reference to mitochondrial-mediated apoptotic cell death
António Alexandre Moreira Ribeiro de Ascensão
Faculdade de Desporto da Universidade do Porto (FADE/UP)

PTDC/SAU-OSM/102362/2008

Grape pomace proanthocyanidins as effective metal chelating agents: significance in human nutrition
Baoshan Sun
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-OSM/102468/2008

Angiogenesis in atherosclerotic lesions: function and potential therapeutic application of the Dll4-Notch signaling pathway
Ana Teresa Fernandes Nunes Tavares
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-OSM/102509/2008

Association between adiposity, components of Metabolic Syndrome and dietary intake in obese children
Flora Correia
Faculdade de Ciências da Nutrição e Alimentação (FCNA/UP)

PTDC/SAU-OSM/102553/2008

Sertoli cell (dys)function in type 1 diabetes-associated reproductive disorder: a study in humans and in animal model
CARLOS PEDRO FONTES OLIVEIRA
Universidade da Beira Interior (UBI)

PTDC/SAU-OSM/102652/2008

IMPACT OF SIRTUIN MODULATION ON THE METABOLIC SYNDROME: FOCUS ON INSULIN RESISTANCE
António Pedro Barros Gomes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/102666/2008

Molecular Nutrition and Colon Cancer
Cristina Maria Da Silveira e Silva Pereira Wilson
Universidade do Minho (UM)

PTDC/SAU-OSM/102712/2008

Age-related and region-specific changes of trace elements levels in human brain. Focus on changes in relation to neurodegenerative diseases
AGOSTINHO ALMIRO DE ALMEIDA
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-OSM/102756/2008

Molecular mechanisms of endothelial progenitor cells dysfunction in diabetes: towards more effective cellular therapies
Rosa Cristina S Fernandes
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OSM/102780/2008

Changes in BDNF-TrkB signaling activity during excitotoxic conditions and neuronal cell death
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/102791/2008

Herbal water extracts interactions with drugs at molecular level (membrane transporter systems)
Maria Luísa Mourato de Oliveira Marques Serralheiro
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-OSM/102838/2008

Novas estratégias para optimizar a diferenciação neuronal a partir de células estaminais derivadas de carcinomas humanos: monóxido de carbono e óxido nítrico
Helena Luisa de Araujo Vieira
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-OSM/103036/2008

Humoral and tissue Doppler characterization of the failing heart of infants with congenital diaphragmatic hernia
Maria João Ribeiro Leite Baptista
Universidade do Minho (UM)

PTDC/SAU-OSM/103315/2008

Use of anti-Dll4 therapy in animal models to improve vascular function in ischemia and in healing of diabetes-associated chronic wounds
António José Freitas Duarte
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-OSM/103521/2008

Interplay between sirtuins and nitric oxide: is PGC-1alpha a common mediator for mitochondrial biogenesis?
Anabela Pinto Rolo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/103836/2008

Adaptation and validation of The Early Feeding Skills Assessment Scale (EFS): A Statistical Validation study with Portuguese Preterm Infants.
João Paulo Maroco Domingos
ISPA,CRL (ISPA)

PTDC/SAU-OSM/103842/2008

Cardiotoxicity and neurotoxicity evaluation of mitoxantrone in in vivo and in vitro models. Determination of genetic polymorphisms and metabolic markers crucial in its toxicity in mitoxantrone-treated patients
Fernando Remião
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-OSM/103849/2008

Molecular mechanisms of Pharmacological and toxicological action of aromatase inhibitors derivatives in combination with antiestrogens for breast cancer therapy
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/104020/2008

Tumour spectrum in cancer hereditary syndromes: Hereditary Diffuse Gastric Cancer as model
Carla Oliveira
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OSM/104330/2008

ILLICIT DRUGS CONSUPTION DURING PREGNANCY: THE UNIQUE ROLE OF MECONIUM TO ASSESS FETAL DRUG EXPOSURE AND ITS IMPLICATIONS IN NEONATAL HEALTH.
Eugenia Gallardo
Universidade da Beira Interior (UBI)

PTDC/SAU-OSM/104464/2008

Development of an anti-ghrelin vaccine for obesity treatment
LÍDIA MARIANA RODRIGUES PEREIRA MONTEIRO
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-OSM/104573/2008

Evaluation of pluripotency in cells expressing the LIM-homeodomain transcription factor islet-1
Luis Afonso Bras Simoes Rosario
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OSM/104668/2008

Regulation of retinal growth factors secretion by Rab GTPases
Jose Silva Ramalho
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OSM/104938/2008

Synthesis, characterization, and toxicity evaluation of gold nanoparticles
Maria de Lourdes Bastos
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-OSM/105014/2008

Treatment of Chronic Myocardial Ischemia with Haematopoietic Precursor Cells
Paulo Bettencourt
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/105015/2008

Assessment of risc morbidity related to TPS in prostate cancer radiotherapy treatment
Nuno José Coelho Gomes Teixeira
Centro Hospitalar Universitário Lisboa Norte, E.P.E. (CHLN)

PTDC/SAU-OSM/105089/2008

BioPor - Portuguese Natural Bioproducts, a new approach in colon chemoprevention, Chemotherapy and Chronic Inflammation
Ana Alexandra Figueiredo Matias
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-OSM/105391/2008

The effects of nutritional/food intervention in the reduction of cardiovascular risk, in HIV patients
Flora Correia
Faculdade de Ciências da Nutrição e Alimentação (FCNA/UP)

PTDC/SAU-OSM/105488/2008

Evaluation of toxicity mechanisms of retinoids derivatives: Studies in models and psoriatic patients or with melanom
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/105572/2008

BIOMARKERS OF DIETARY ACRYLAMIDE EXPOSURE: HUMAN TOXICOLOGICAL RELEVANCE.
Jorge Francisco Dias Rodrigues Gaspar
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-OSM/105656/2008

Identification of proliferetion and differentiation control mechanisms present in cardiac stem cells
Luis Afonso Bras Simoes Rosario
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-OSM/105671/2008

Transcriptional regulatory networks mediated by the farnesoid X receptor - physiological relevance of structural diversity
Vera Ribeiro Marques
Universidade do Algarve (UAlg)

PTDC/SAU-OSM/107952/2008

PRODIAMET - Nutritional intervention via PRObiotic strains in type 2 DIAbetes: control of inflaMmatory and mETabolic responses
DAVIDE MAURÍCIO DA COSTA CARVALHO
Hospital de São João EPE (HSJ)

PTDC/SAU-OSM/107993/2008

Study of the Interactions between Fullerenes and Biological Systems: Biomedical and Toxicological Implications
Romeu António Videira
Instituto Politécnico de Viseu (IPV)

PTDC/SAU-OSM/108065/2008

Erithropoietin and amyloid: Extricating the mechanisms of protein aggregation toxicity in the anemia of FAP.
Paulo Manuel de Castro Pinho e Costa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-OSM/108086/2008

Cumulus oophorus cells and follicular fluid biomarkers for oocyte quality assessment
Henrique Almeida
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/108167/2008

A new surgical approach for the treatment of coronary disease
Artur Manuel Perez Neves Aguas
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-OSM/108267/2008

Tolerance induction to recombinant clotting factors in a murine model of hemophilia
Vanessa Alexandra Gonçalves de Oliveira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OSM/108376/2008

Mitochondrial fatty acid oxidation disorders - a proteome approach for improved analysis of mitochondrial dysfunction.
Laura Ferreira Teixeira Vilarinho
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-OSM/108444/2008

Therapeutic Interruption of Advanced Glycation in Diabetes and Metabolic Syndrome
Raquel Maria Fino Seiça
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-OSM/108666/2008

Nutritional modulation of inflammation, oxidative stress and apoptosis associated with cardiac cachexia.
Joaquim Adelino Correia Ferreira Leite Moreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/108828/2008

DEVELOPMENT OF SAFE PARAQUAT FORMULATIONS AND ANTIDOTES FOR THE TOXICITY OF THIS HERBICIDE: A PRE-CLINICAL AND FORENSIC APPROACH
Félix Carvalho
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-OSM/108917/2008

Modifications of autonomic function on young ischemic-stroke patients
Maria Isabel de Sousa Rocha
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OSM/108966/2008

The influence of the genes related to the secretion of adrenal androgens on the ovary
Duarte Luis Pignatelli Dias Almeida
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OSM/108971/2008

Cellular senescence emerging in the context of exposure to cytotoxic drugs
João António Augusto Ferreira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OSM/109069/2008

Identification of the penile circulatory dynamical changes in erectile dysfunction
Nuno José Duarte Monteiro Pereira
COFAC, Cooperativa de Formação e Animação Cultural, CRL (COFAC)

PTDC/SAU-OSM/109081/2008

Genetic modification of the paraventricular nucleus of the hypothalamus (PVN) and rostroventrolateral medula (RVLM) cells to control hypertension chronically.
Maria Isabel de Sousa Rocha
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-OSM/109098/2008

The Role of Oxidative Stress in Cigarette Smoking-Induced Cardiovascular Lesions
António Albino-Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-BEB/098391/2008

LIGHT DISTORTION ANALYZER: DEVELOPEMENT AND APPLICATIONS
JOSÉ MANUEL GONZÁLEZ MÉIJOME
Universidade do Minho (UM)

PTDC/SAU-BEB/098392/2008

OPTICAL SOLUTIONS FOR PRESBYOPIA CORRECTION
JOSÉ MANUEL GONZÁLEZ MÉIJOME
Universidade do Minho (UM)

PTDC/SAU-BEB/098468/2008

Heart regeneration by embryonic vascular cells and a biomimetic scaffold
Lino Ferreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-BEB/099042/2008

Nanosensor for assessing the risk of a Cardiovascular Disease Risk Nanosensor (CARDIOSENSOR)
Teresa Alexandra Peixoto Rocha Santos
Instituto Piaget, Cooperativa para o Desenvolvimento Humano, Integral e Ecológico CRL (IPiaget)

PTDC/SAU-BEB/099954/2008

Incorporation of inflammatory signals in the development of biomaterials for bone repair/regeneration: an integrated approach
Mário Barbosa
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BEB/100147/2008

New methodological advances in Diffusion Spectrum MRI and its implications for structure-function correlations in brain imaging
Nicolas Francisco Lori
Universidade de Coimbra (UC)

PTDC/SAU-BEB/100392/2008

Wireless biomedical microsystem for neural implants
José Higino Gomes Correia
Universidade do Minho (UM)

PTDC/SAU-BEB/100650/2008

Development and characterization of new sensors for hemodynamic assessment
Carlos Manuel Bolota Alexandre Correia
Associação para o Desenvolvimento do Departamento de Física da Universidade de Coimbra (ADDFUC/FCT/UC)

PTDC/SAU-BEB/100866/2008

Optical Eye-Tracking for Cochlear Implant Re-parametrization
Joao Manuel Cardoso
Associação para o Desenvolvimento do Departamento de Física da Universidade de Coimbra (ADDFUC/FCT/UC)

PTDC/SAU-BEB/100875/2008

FabryScreen - Screening for Fabry disease based on automatic classification of chromatographic images
Ana Maria Rodrigues de Sousa Faria de Mendonça
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BEB/101235/2008

BIOMATRIX-Multifunctional extracellular matrix-analogues as biomaterials for bone regeneration
Cristina Maria Santos Alves de Carvalho Barrias
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BEB/101719/2008

Development of a laser Doppler flowmeter for human microvascular blood flow analysis: discrimination between capillary blood flow and shunted blood flow
Luís Filipe Requicha Ferreira
Associação para o Desenvolvimento do Departamento de Física da Universidade de Coimbra (ADDFUC/FCT/UC)

PTDC/SAU-BEB/101943/2008

Adventitious lung sounds as indicators of severity and recovery of lung pathology and sputum location
Alda Marques
Universidade de Aveiro (UA)

PTDC/SAU-BEB/103034/2008

Antibacterial and Osteogenic behaviour of Modified Calcium Phosphates (MCP): In vitro and In vivo Evaluation
NANDYALA SOORAJ HUSSAIN
Instituto de Engenharia de Sistemas e Computadores do Porto (INESC Porto/FE/UP)

PTDC/SAU-BEB/103151/2008

Evaluation of blood-retinal barrier functional alterations by optical coherence tomography.
Rui Manuel Dias Cortesão dos Santos Bernardes
Universidade de Coimbra (UC)

PTDC/SAU-BEB/103228/2008

Design of composite chemical sensors and biosensors for real-time and simultaneous monitoring of nitric oxide and oxygen in vivo in the brain.
Rui Manuel Silva Gomes Barbosa
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-BEB/103368/2008

3DPectus system: automatic and personalized molding/bending of surgical prosthesis with embedded stabilizers, without radiation, and virtual simulation of the postsurgical cosmetic outcome.
João Luís Araújo Martins Vilaça
Universidade do Minho (UM)

PTDC/SAU-BEB/103408/2008

Software development for arthroplasty preparation
RUI MIGUEL BARREIROS RÚBEN
Instituto Politécnico de Leiria (IPLeiria)

PTDC/SAU-BEB/103471/2008

ADDI - Automatic computer-based Diagnosis system for Dermoscopy Images
Teresa Maria Gouveia Torres Feio Mendonça
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/SAU-BEB/103667/2008

GALENO - Modeling and Control for personalized drug administration
Teresa Maria Gouveia Torres Feio Mendonça
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/SAU-BEB/104183/2008

neuroCornea - Diabetic peripheral neuropathy early diagnosis and follow-up through in vivo automatic analysis of corneal nerves morphology
Antonio Miguel Lino Santos Morgado
Universidade de Coimbra (UC)

PTDC/SAU-BEB/104630/2008

RPC-PET - A novel technology for single-bed whole-body human molecular imaging with higher sensitivity and resolution
Joao Jose Pedroso Lima
Laboratório de Instrumentação e Física Experimental de Partículas (LIP)

PTDC/SAU-BEB/104643/2008

Development of an electrochemical biosensor for sceening of new anti-cancer drugs based on the inhibition of tyrosine kinase enzyme
Victor-Constantin Diculescu
Instituto Pedro Nunes - Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia (IPN)

PTDC/SAU-BEB/104995/2008

Assistive Real-Time Technology in Singing
Aníbal João Sousa Ferreira
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-BEB/105650/2008

CSD-Chip - Development of an integrated biomedical microdevice for blood cell separation and deformation
Rui Lima
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-BEB/108644/2008

FIBDOSE: fiber dosimeters for in vitro and in vivo dosimetry in External Radiotherapy and Brachytherapy
Carla Susana Santana Carmelo Rosa
Instituto de Engenharia de Sistemas e Computadores do Porto (INESC Porto/FE/UP)

PTDC/SAU-BEB/108658/2008

Clinical and Biomechanical Assessement of Dental Implants Submited to Platform Switching
Pedro Miguel Gomes Nicolau
Universidade de Coimbra (UC)

PTDC/SAU-BEB/108728/2008

Hemo-Networks - Experimental and computational investigations of the factors influencing blood flow in microvascular networks.
Ricardo Frederico Pereira Dias
Instituto Politécnico de Bragança (IPBragança)

PTDC/SAU-NEU/098683/2008

Nociceptive processing on projecting and non-projecting neurons in the spinal lamina I
Boris Safronov
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/099007/2008

Understanding the role of the axon/glia functional unit during developmental myelination and in remyelination
Joana Paes de Faria
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/099075/2008

Life and death of retinal ganglion cells: unmasking the neuromodulatory and neuroprotective roles of Neuropeptide Y
António Francisco Rosa Gomes Ambrósio
Universidade de Coimbra (UC)

PTDC/SAU-NEU/099307/2008

The role of calpain-mediated proteolysis of ataxin-3 in Machado-Joseph disease: a molecular therapy approach with viral vectors
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/099440/2008

Molecular Mechanisms of Synaptic Traffic of Glutamate Receptors of the NMDA Type
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/100701/2008

Cognition and synaptic function in calcium channel disease
Isabel Alexandra Azevedo Silveira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/100729/2008

Demonstrating that A2A adenosine receptors control glutamatergic synaptic plasticity through CB1 cannabinoid receptors in the striatum, thus providing attracting therapeutic targets
Attila Köfalvi
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/100773/2008

Neural correlates of value in the corticostriatal reward-aversion circuitry
Vasco Miguel Clara Lopes Galhardo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/101090/2008

Hypertension and painful neuropathy in diabetes. Role of angiotensin II and oxidative stress in central nervous system.
Dora Pinho
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NEU/101726/2008

Development of a micro-probe for capillary laser Doppler flowmetry in rat brain
Luís Filipe Requicha Ferreira
Associação para o Desenvolvimento do Departamento de Física da Universidade de Coimbra (ADDFUC/FCT/UC)

PTDC/SAU-NEU/101783/2008

Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis: new targets for brain repair therapies.
AGASSE Fabienne
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/101928/2008

Deciphering the molecular mechanisms linking alpha-synuclein dysfunction and cytotoxicity in Parkinson's disease - the role of GDNF
Ana Cristina Carvalho Rego
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/101995/2008

Role of early neuronal nociceptive fate determinants in the adult mouse under chronic pain
Deolinda Maria Valente Alves Lima Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NEU/102075/2008

SWORD - Stroke Wearable Operative Rehabilitation Devices Development and clinical validation of an intelligent vibratory wearable device to improve rehabilitation in stroke patients.
Maria Paula Mourao do Amaral Coutinho
Unidade Local de Saúde de Entre Douro e Vouga, EPE (CHEDV)

PTDC/SAU-NEU/102612/2008

Mechanisms underlying the effects of nitric oxide on neural stem cell proliferation in brain injury
Caetana Angelica Ermitao Monteiro Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/102710/2008

Mitochondrial-dependent impairment of intracellular trafficking in Parkinson's disease
Sandra Morais Cardoso
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/103325/2008

The pathological interaction between diabetes and Alzheimer's disease: exploring the role of brain endothelial mitochondria and uncoupling proteins
PAULA ISABEL DA SILVA MOREIRA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/103538/2008

In vivo dynamics of nitric oxide in the brain: regulation of cellular respiration and implications for Alzheimer´s disease and aging
João António Nave Laranjinha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/103728/2008

Analysis of the hippocampal proteome in mice exposed to psychotropic medication
BRUNO JOSÉ FERNANDES OLIVEIRA MANADAS
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/103904/2008

Structure and dynamics of neural networks
Alexander Goltsev
Universidade de Aveiro (UA)

PTDC/SAU-NEU/104100/2008

The role of mRNA translation in the formation of the neuromuscular junction
Ramiro Almeida
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/104297/2008

Regulation of hnRNPs by the neurotrophin BDNF: role in synaptic plasticity
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/104415/2008

Histamine versus antihistamines: new modulators of neurogenesis?
LILIANA INÁCIO BERNARDINO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/105180/2008

Multimodal analysis of the neurobiology of depression
Nuno Jorge Carvalho de Sousa
Universidade do Minho (UM)

PTDC/SAU-NEU/108110/2008

Effect of caffeine and adenosine A2A receptors on stress response: role of adrenal gland modulation
CLÁUDIA MARGARIDA GONÇALVES CAVADAS
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/108557/2008

Abnormal emotional and cognitive behaviours in chronic pain states: spatiotemporal characterization of CNS plastic correlatives
Armando Almeida
Universidade do Minho (UM)

PTDC/SAU-NEU/108668/2008

Role of adenosine A2A receptors in microglia and glutamatergic synapses in the control of synaptic plasticity and brain damage
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NEU/108992/2008

Neurovascular coupling between neuronal activity and blood flow in brain mediated by nitric oxide
João António Nave Laranjinha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ESA/100107/2008

HERA - Environmental Risk Assessment of a contaminated estuarine environment: A case study
SANDRA SOFIA FERREIRA DA SILVA CAEIRO
IMAR - Instituto do Mar (IMAR)

PTDC/SAU-ESA/100666/2008

COMPARATIVE STUDY OF THE PREVALENCE OF ATOPIC SENSITISATION AND ALLERGIC DISEASE IN ELDERLY AND YOUNG PORTUGUESE ADULTS
Luis Manuel Taborda Barata
Universidade da Beira Interior (UBI)

PTDC/SAU-ESA/100841/2008

Regression methods for multiple outcomes in Health research
Armando Rogerio Martins Teixeira Pinto
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ESA/103958/2008

Determinants of Helicobacter pylori infection: a lifecourse approach
Nuno Miguel de Sousa Lunet
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/105033/2008

Early development of obesity and the metabolic syndrome
Ana Cristina Santos
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/105530/2008

An educational intervention to improve the use of antibiotics in Portuguese Health Professional: cluster-randomized trial.
Maria Teresa Ferreira Herdeiro
Universidade de Aveiro (UA)

PTDC/SAU-ESA/107940/2008

A pharmacoepidemiological approach to the study of prognosis in acute and chronic heart failure
Ana Azevedo
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/108315/2008

Peripheral body fat, lifestyles and adipokines
Carla Maria de Moura Lopes
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/108407/2008

Determinants of optimal bone acquisition in adolescence: the role of low grade inflammation on bone accrual and remodelling
JOSÉ HENRIQUE DIAS PINTO DE BARROS
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/108577/2008

Eating habits in preschool children: a longitudinal approach to the identification of determinants and effects on body composition
Carla Maria de Moura Lopes
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-ESA/108636/2008

Alternaria infectoria FKS, CHS and melanin synthesis genes: the combination for oportunism
Teresa Maria Fonseca de Oliveira Gonçalves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ESA/108871/2008

Environmental risk factors for cardiovascular disease in Porto Metropolitan Area
AGOSTINHO ALMIRO DE ALMEIDA
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-MII/098041/2008

A systematic method for identifying the ligands of T-cell surface molecules
Alexandre Carmo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MII/098567/2008

Dissecting the molecular mechanisms of wound healing in diabetes - the role of neuropeptides
EUGÉNIA MARIA LOURENÇO DE CARVALHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MII/099102/2008

The mycobacterial granuloma
Rui Appelberg Gaio Lima
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MII/100588/2008

Functional and biological characterization of SSc5D, a novel molecule of the Scavenger Receptor Cysteine-rich family
Alexandre Carmo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MII/101663/2008

Infection of the thymus by mycobacteria: implications for the immune response, therapy and latency in tuberculosis
Margarida Correia-Neves
Universidade do Minho (UM)

PTDC/SAU-MII/101977/2008

BCG vaccination: a tool to identify new correlates of protection and pathology in experimental infection with Mycobacterium tuberculosis.
António Gil Pereira de Castro
Universidade do Minho (UM)

PTDC/SAU-MII/107942/2008

Retroviral-like membrane-associated aspartic proteinases from Rickettsiae: potential new therapeutic targets for rickettsioses.
Isaura Isabel Gonçalves Simões
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/SAU-FCF/098685/2008

Impact of methamphetamine on the blood-brain barrier: unmasking the underlying mechanisms and the role of neuroinflammation
Ana Paula Pereira da Silva Martins
Universidade de Coimbra (UC)

PTDC/SAU-FCF/099082/2008

Caloric restriction increases lifespan: role of neuropeptide Y on autophagy
CLÁUDIA MARGARIDA GONÇALVES CAVADAS
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/100423/2008

Role of ATP and its P2Y1 receptors in neuroprotection
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/100442/2008

Role of the neuregulin system in pulmonary arterial hypertension - pathophysiological and therapeutic implications
Carmen Dulce da Silveira Brás Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FCF/100749/2008

Implication of sirtuin proteins in the regulation of antigen presenting cells apoptosis during leishmaniasis: a therapeutic approach
Ricardo Jorge Leal Silvestre
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FCF/100930/2008

Molecular and nanotechnology-based approaches to improve the antitumor activity of small molecules
Madalena Maria Magalhães Pinto
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FCF/101017/2008

Role and mechanism of action of immunoregulatory iNKT and DC cells in Leishmania infection: new approaches for vaccination?
Anabela Cordeiro-da-Silva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FCF/101177/2008

A role for Nrf2/ARE cytoprotective signalling in iron overload. Adaptive response to oxidative stress as a disease modifier in HFE-associated hereditary hemochromatosis.
Tiago Pereira de Lacerda Costa Duarte
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FCF/102415/2008

The Neuropeptide Y (NPY) and Dipeptidyl-peptidase IV (DPPIV) as new promising targets on the adipose tissue regulation in obesity
Joana Salgado
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/102958/2008

IMPLICATIONS OF AMPHETAMINE PSYCHOSTIMULANTS ABUSE IN BRAIN AGING
João Paulo Capela
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/104347/2008

Monocarboxylate transporters as potential therapeutic targets in cancer: inhibition studies in solid tumor models
Maria de Fátima Monginho Baltazar
Universidade do Minho (UM)

PTDC/SAU-FCF/104448/2008

Development and validation of a pharmacokinetic/pharmacodynamic model to individualize carboplatin and gemcitabine doses for elderly patients with advanced non-small cell lung cancer
Paula Maria Façanha da Cruz Fresco
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FCF/104492/2008

NanoFreeze - Freeze-drying approaches for overcoming instability of therapeutic proteins encapsulated into nanoparticles
Bruno Sarmento
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FCF/105429/2008

Anti-inflammatory mechanism and properties of medicinal plants: a multidisciplinary research for their validation and utilization as a source of phytopharmaceuticals
Maria Teresa Pereira Marques Batista
Universidade de Coimbra (UC)

PTDC/SAU-FCF/108056/2008

Analysis of transcription deregulation in brain and peripheral Huntington's disease models - influence of modulating histone deacetylases
Ana Cristina Carvalho Rego
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FCF/108263/2008

Fibroblasts as mechano-sensory signalling intermediates between epithelia and primary afferent neurons: Role of extracellular ATP, purinoceptors and [Ca2+]i waves
Paulo Correia de Sá
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-FCF/108462/2008

Is there a place for adenosine mediating impairment of both neuromuscular and immunological synapses in myasthenics?
Laura Oliveira
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-OBD/099886/2008

Molecular mechanisms modulating Prrxl1-mediated development of pain-processing neurons
Carlos Reguenga
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OBD/100261/2008

Dissecting the cross-talk between mitotic checkpoint, ageing and cancer: towards the understanding of cell fate after mitotic slippage
Elsa Logarinho
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OBD/101242/2008

Transcriptional and post-transcriptional mechanisms of LRP1B inactivation in sporadic and familial non-medullary thyroid cancer.
Ana Paula Soares Dias Ferreira
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OBD/104017/2008

The role of Protein Quality Control in the regulation of E-cadherin and its relevance in cancer.
Gianpaolo Suriano
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-OBD/105111/2008

The role of molecular clock genes in temporal control of mesoderm patterning in vertebrate embryos
Raquel Gláucia Varzielas Pego de Andrade
Universidade do Minho (UM)

PTDC/SAU-OBD/108051/2008

Molecular Mechanisms of Temporal-Spatial Control of Embryonic Lung Development
Jorge Manuel Nunes Correia Pinto
Universidade do Minho (UM)

PTDC/SAU-GMG/098305/2008

Mapping and identification of new disease genes in autosomal dominant spinocerebellar ataxias
Isabel Alexandra Azevedo Silveira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/098419/2008

Molecular genetics and functional genomics of pituitary hormone deficiencies
Manuel Lemos
Universidade da Beira Interior (UBI)

PTDC/SAU-GMG/098850/2008

Functional genomics of ribosome infidelity phenotypes associated to human diseases.
Manuel António Silva Santos
Universidade de Aveiro (UA)

PTDC/SAU-GMG/099704/2008

Functional dissection of mitotic spindle assembly pathways by comparative genomics
Helder Jose Martins Maiato
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/100240/2008

Phenotypic variability and modifier genes in Familial Amyloid Polyneuropathy (FAP ATTRV30M)
Alda Maria Botelho Correia de Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/100913/2008

Search for disease modifiers in spinocerebellar ataxias: human and animal-based approaches
Isabel Alonso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/101229/2008

Search for genomic structural variants in azoospermia: a study in the Portuguese population
Alexandra Manuel Ferreira Lopes
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-GMG/101572/2008

Ataxin-3: gain and loss of function in Machado-Joseph disease
Patrícia Espinheira de Sá Maciel
Universidade do Minho (UM)

PTDC/SAU-GMG/105344/2008

LIMP-2 studies: from clinical genetics to functional genomics and back
Maria Clara Pereira de Sá Miranda
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OSM/099422/2008

Skingineering - Engineering skin analogues through cell sheet technology
Alexandra P Marques
Universidade do Minho (UM)

PTDC/SAU-OSM/099762/2008

In vitro alternative approach for chemical skin sensitization hazard: an EU legislation demand
Maria Teresa Cruz
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/100630/2008

Neuroprotecting mechanisms of carnitine in mitochondrial dysfunction
Maria Teresa Burnay Summavielle
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-OSM/101437/2008

Development and application of P-glycoprotein inducers for the prophylaxis and therapeutics of xenobiotics toxicity
Fernando Remião
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-OSM/101469/2008

NPwhY - Innervation and angiogenesis for the benefit of osteogenesis: the involvement of NPY neuronal pathway in bone repair
Meriem Lamghari Moubarrad
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-OSM/102083/2008

AngioPaX - ELUCIDATING THE ANGIO/VASCULOGENIC PARADOX IN DIABETES
Raquel Soares
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/102239/2008

Diabetes and placental function: the role of hyperglycaemia, oxidative stress and inflammation
Fátima Martel
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-OSM/102907/2008

Role of dietary polyphenols on intestinal inflammation either as single agents or in combination with anti-inflammatory drugs by using in vitro and in vivo models
Leonor Martins Almeida
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/103226/2008

Correlation phenotype/genotype in diabetic retinopathy
MARIA DA CONCEIÇÃO LOPES LOBO DA FONSECA
Universidade de Coimbra (UC)

PTDC/SAU-OSM/103647/2008

Discovery and functional characterization of novel disease-related proteins involved in lipid metabolism and organelle dynamics
Michael Schrader
Universidade de Aveiro (UA)

PTDC/SAU-OSM/104124/2008

Molecular mechanisms of heart failure - the role of the adipocyte as an endocrine organ
Daniel Omar Espinoza
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-OSM/104369/2008

Pathophysiological role of purines (ATP and adenosine) in the human bladder hyperactivity
Paulo Correia de Sá
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-OSM/104475/2008

Neudesina - estudo da função de um novo factor neurotrófico
JOÃO CARLOS SOUSA
Universidade do Minho (UM)

PTDC/SAU-OSM/104731/2008

Title: Clarification of the Mitochondrial Role in the Cardiotoxicity of Doxorubicin Using a Whole Heart Perfusion System - Impact of Different Doxorubicin Treatment Regimens
António Moreno
IMAR - Instituto do Mar (IMAR)

PTDC/SAU-OSM/105578/2008

Pre-clinical Assessment of the Safety and Advantages of Natural Orifice Transluminal Endoscopic Surgery (NOTES)
Estêvão Augusto Rodrigues de Lima
Universidade do Minho (UM)

PTDC/SAU-OSM/105663/2008

Mapping the metabolic and neuromodulator role of insulin in the hippocampus
Attila Köfalvi
Centro de Neurociências e Biologia Celular (CNBC/UC)