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R&D Projects

Call for Funding of Research and Development Projects in all Scientific Domains - 2009

Painel de Avaliação da área de Engenharia Biológica e Biotecnologia - 2009

Coordination

Nic D. Lindley

Evaluation

John Villadsen
John Woodley
Juan Manuel Lema
Manuel Cánovas
Mohamed Al-Rubeai
Nic D. Lindley

Projects assigned

PTDC/EBB-EBI/110107/2009

ANDROMEDA: Alleviation of pollutioN Derived from nitRogen Oxides, via MicroalgaE in Dedicated bioreActors
Francisco Xavier Delgado Domingos Antunes Malcata
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/EBB-EBI/110139/2009

Extraction of Bioactive Compounds from Marine Seaweeds and Microalgae
Maria do Carmo Pinto Basto Avides Moreira
Universidade do Minho (UM)

PTDC/EBB-EBI/110973/2009

Towards a high-throughput drug discovery platform for the screening of GPCR targets in cells
Duarte Miguel de França Teixeira dos Prazeres
Instituto Superior Técnico (IST/ULisboa)

PTDC/EBB-EBI/111047/2009

mCARD-FISH - Improving CARD-FISH for the in situ visualization of single or low-copy nucleic acid sequences in microorganisms.
Nuno Filipe Azevedo
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/EBB-EBI/111128/2009

Alternative oxidase (AOX) and metabolic reorganization during stress-induced cell re-differentiation in Daucus carota L.
Birgit Arnholdt-Schmitt
Universidade de Évora (UE)

PTDC/EBB-EBI/111145/2009

Use of ACC deaminase in rhizobia as a strategy to promote growth and stress tolerance in legumes
Isabel Solange Martins de Oliveira
Universidade de Évora (UE)

PTDC/EBB-EBI/111191/2009

Bioenergy production
Nuno Paulo Correia e Afonso Moreira
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/EBB-EBI/111222/2009

Connecting design to function in metabolic networks
Armindo José Alves da Silva Salvador
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/EBB-EBI/111302/2009

Engineering fucose enriched polysaccharide synthesis by Enterobacter sp. A47: from gene to product
Maria Filomena Andrade de Freitas
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/EBB-EBI/111308/2009

MicroBioOils - Oleaginous Microorganisms, alternative raw-material for sustainable Biodiesel production
Sara Raposo
Universidade do Algarve (UAlg)

PTDC/EBB-EBI/111386/2009

Role of Metabolism in generating, expanding and differentiating Induced Pluripotent (iPS) Cells
João RamalhoSantos
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/EBB-EBI/111699/2009

FLUOROPHARMA - Biodegradation and removal of chiral and achiral fluorinated pharmaceuticals from wastewaters
Paula Castro
Universidade Católica Portuguesa (UCP)

PTDC/EBB-EBI/111723/2009

StresSys: a Systems Biology Approach to Study the General Stress Response in Bacteria
Anália Maria Garcia Lourenço
Universidade do Minho (UM)

PTDC/EBB-EBI/111893/2009

4BIO - Biomethane and biohydrogen production for maximal energy recovery in a biorefinary concept
José Carlos Gomes da Costa
Universidade do Minho (UM)

PTDC/EBB-EBI/112200/2009

EngBioethanol - Physiological engineering of industrial yeast for high-productivity second generation bioethanol production
Lucília Maria Alves Ribeiro Domingues
Universidade do Minho (UM)

PTDC/EBB-EBI/112504/2009

SupercriticalStimuli - Development of stimuli responsive substrates for cell growth and expansion
Ana Rita Cruz Duarte
Universidade do Minho (UM)

PTDC/EBB-EBI/112579/2009

Production of glycosyltransferases to construct a library of glycoconjugates with biological and clinical applications
Júlia Carvalho Costa
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/EBB-EBI/112748/2009

POLYPULP - Valorization of a sub-product from pulping industry through the production microbial polyesters
Luísa Alexandra Seuanes Serafim Leal
Universidade de Aveiro (UA)

PTDC/EBB-EBI/112789/2009

BioSynFinery - Bridging biotechnology and the thermochemical syngas biorrefinery platform
Maria Madalena dos Santos Alves
Universidade do Minho (UM)

PTDC/EBB-EBI/112902/2009

MabCapture - A novel approach for the clarification and isolation of monoclonal antibodies using phenyl boronate continuous bed chromatography
Ana Margarida Nunes da Mata Pires de Azevedo
Instituto Superior Técnico (IST/ULisboa)

PTDC/EBB-EBI/113010/2009

Hybrid Nanostuctured Hydrogels: Bone regeneration using multifunctional injectable hydrogels
José Domingos Santos
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/EBB-EBI/113077/2009

Developing a new therapeutic approach for prostate cancer
Anabela Mota Pinto
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/EBB-EBI/113096/2009

GeNANO-Target: Nanotecnologia genética aplicada ao direccionamento activo a tumores sólidos
Eliana Souto
Fundação Ensino e Cultura Fernando Pessoa (FECFP)

PTDC/EBB-EBI/113130/2009

Recovering Energy from Waste: Bioconversion of Glycerol to Hydrogen via Dark/Photo-Fermentation
Adrian Oehmen
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/EBB-EBI/113161/2009

New targets in the immunoprophylaxy of Toxoplasmosis
Susana Adelaide da Natividade Rodrigues de Sousa
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/EBB-EBI/113439/2009

BIOCOFFEE: Bioactive compounds recovery from spent coffee ground
Solange Inês Mussatto Dragone
Universidade do Minho (UM)

PTDC/EBB-EBI/113650/2009

Melhoramento da imunogenicidade de vacinas de DNA
Gabriel António Amaro Monteiro
Instituto Superior Técnico (IST/ULisboa)

PTDC/EBB-EBI/113727/2009

PhytoLac - Engineered Lactococcus lactics for the optimized production of nutraceutical plant-derived polyphenols
Ana Rute Ramos Neves
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/EBB-EBI/113824/2009

In silico reconstruction of Streptococcus pneumoniae cellular networks and their impact on virulence
Francisco Rodrigues Pinto
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/EBB-EBI/113864/2009

NANOGEL: Nanobiotechnology for vaccine formulations
Francisco Miguel Portela da Gama
Universidade do Minho (UM)

PTDC/EBB-EBI/114291/2009

A Systems Biology methodology for advanced culture medium design: towards a phenotype guided medium design platform
Rui Manuel Freitas Oliveira
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/EBB-EBI/114358/2009

PolyEndo- Polymicrobial endocarditis: new control perspectives
Domingas do Rosario Verissimo Jacinto Tavares de Oliveira
Universidade do Minho (UM)

PTDC/EBB-EBI/114390/2009

Symbiosis in Glycine max L.: strategies for production of bioactive compounds
Paula Cristina Branquinho de Andrade
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/EBB-EBI/114597/2009

Dieselzyme: Desenvolvimento de novos biocatalisadores para produção sustentável de biodiesel
Pedro Miguel Vidinha Gomes
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/EBB-EBI/114724/2009

Integrated Methodologies for the Development of heterologous prime-boost Vaccines
Lídia Maria Diogo Gonçalves
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/EBB-EBI/114874/2009

Biosynth: Metodologias para a síntese de alcalóides de valor acrescentado ancoradas em matrizes biológicas, a partir de matérias primas renováveis
PEDRO CARLOS DE BARROS FERNANDES
Instituto Superior Técnico (IST/ULisboa)

PTDC/EBB-EBI/114926/2009

BioHA - Hydroxyapatite production, with high biocompatibility, using an oscillatory flow reactor
António Manuel Azevedo Ferreira
Universidade do Minho (UM)

PTDC/EBB-EBI/115498/2009

Polymeric nanofibers as new class of 3D scaffold and their application in stem cell research and tissue engineering
Fouzi Mouffouk
Universidade do Algarve (UAlg)

PTDC/EBB-EBI/115736/2009

Characterization of Helicobacter pylori by FTIR-spectroscopy for strain typing, diagnosis, personalized therapy, epidemiological surveillance and drug screening
Cecília Ribeiro da Cruz Calado
Universidade Católica Portuguesa (UCP)

PTDC/EBB-EBI/115830/2009

MarCru - Marine Crustraceans as source of chitin
Sérgio Miguel Franco Martins Leandro
Instituto Politécnico de Leiria (IPLeiria)

PTDC/EBB-EBI/115904/2009

Waste to Energy Approach in Winery Wastewater Treatment
Domingas do Rosario Verissimo Jacinto Tavares de Oliveira
Universidade do Minho (UM)

PTDC/EBB-EBI/116018/2009

Baculovirus transduction in mammalian cells: A novel strategy for recombinant protein production
Pedro Estilita Pereira Monteiro da Cruz
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/EBB-EBI/116027/2009

New human amniocyte-derived cells for the production of biopharmaceuticals using transient transfection
Pedro Estilita Pereira Monteiro da Cruz
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/EBB-EBI/116066/2009

INDY-2G - Microbial cell factories for second generation bioethanol biorefineries: evolutionary engineering in lignocellulose hydrolysates
FRANCISCO MANUEL FERREIRA GIRIO
Laboratório Nacional de Energia e Geologia, I.P. (LNEG)

PTDC/EBB-EBI/116239/2009

Computational Fluid Dynamics in Fetal and Neonatal Cardiovascular System
Abel Rouboa
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/EBB-BIO/109802/2009

PhotoWeed - Environmental remediation of pollutants by integrating the PHOTO-Fenton process and WEED plants
ARMANDO JORGE GOMES TEIXEIRA
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/EBB-BIO/110060/2009

"Intelligels" - The Formulation Of Green Biosensors.
Abid Hussain
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/EBB-BIO/111146/2009

Development of a targeted nanosystem for systemic delivery in miRNA-based therapeutics: A new non-viral gene therapy approach for glioblastoma multiform
Maria da Conceição Monteiro Pedroso de Lima
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/EBB-BIO/111236/2009

Membrane bioreactor process for the synthesis of hydroxamic acids derivatives demonstrating therapeutic properties.
Rita Pacheco
Instituto Superior de Engenharia de Lisboa (ISEL/IPL)

PTDC/EBB-BIO/111240/2009

Notch up Hematopoietic Stem Cells: Expansion of Hematopoietic Stem Cells through a novel Notch signaling-platform
Raquel Madeira Gonçalves
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/EBB-BIO/111392/2009

Design of whole-cell biotransformation systems in Pseudomonas putida
Lígia Maria Oliveira Martins
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/EBB-BIO/111530/2009

hCE-2 - expression and characterization in in vitro and in silico models
Ana Luisa Ferreira Simplicio
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/EBB-BIO/111646/2009

A proteomic approach to increase Streptomyces fermentation yields by modulating the oxidative stress response
Marta Vaz Mendes
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/EBB-BIO/111662/2009

LEPTOkit - Veterinary diagnostic NAT kits to detect and typify pathogenic Leptospira infecting production animals
Joao Inacio Silva
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/EBB-BIO/111668/2009

Bridging systems biology and engineering to improve biotechnological production
Zita Irene Tany Antoinette Soons
Universidade do Minho (UM)

PTDC/EBB-BIO/112064/2009

PROBIOCLA: PRoduction of cOnjugated linoleic acid by microBial fermentation: screening of straIns,novel prOCess strategies, and technoLogical and biologicAl validation
Ana Maria Pereira Gomes
Universidade Católica Portuguesa (UCP)

PTDC/EBB-BIO/112123/2009

Exploitation of proteins of the Burkholderia cepacia complex to design new diagnostic and therapeutic strategies to fight the infections caused by these pathogens
Sílvia Andreia Sousa
Instituto Superior Técnico (IST/ULisboa)

PTDC/EBB-BIO/112196/2009

Nanofix - Evolution of a novel metabolic network for CO2 fixation
Raquel M Silva
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/EBB-BIO/112204/2009

BIODEGRADATION OF HIGH MOLECULAR WEIGHT POLYCYCLIC AROMATIC HYDROCARBONS (PAHS) BY ACTINOBACTERIA spp.
Andrea Zille
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/EBB-BIO/112278/2009

Dynamic Systems Analysis to Body Composition Evaluation for Diagnosis use
Maria Teresa Braga Valente de Almeida Restivo
Instituto de Engenharia Mecânica (IDMEC)

PTDC/EBB-BIO/112585/2009

GLP-1 for the control and treatment of diabetes and obesity: Nano-encapsulating systems and its physic-chemical and toxicological characterization.
Amélia Maria Lopes Dias da Silva
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/EBB-BIO/112602/2009

AGRIMETAL - Metal extraction from optimized cultivars of hyperaccumulator plants
João António Mendes Serra Pratas
Universidade de Coimbra (UC)

PTDC/EBB-BIO/112786/2009

3D in vitro models for reducing animal experimentation in pharmaceutical development: integrative approaches for prediction of hepatic drug metabolism and neurotoxicity
Ana CATARINA Maurício BRITO Ataíde Montes
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/EBB-BIO/112794/2009

INDYEAST- Physiological and molecular characterization of industrial yeast strains: a prerequisite for the design of bioethanol producers
Catarina Paula Guerra Geoffroy Prista
Instituto Superior de Agronomia (ISA/ULisboa)

PTDC/EBB-BIO/112887/2009

Development of novel therapeutic antibodies by viral mutagenesis
Joao Goncalves
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/EBB-BIO/113063/2009

Improving the biotechnological potential of a source of highly valuable pharmaceutical drugs: Development of an efficient method for the production of transgenic plants of Catharanthus roseus.
Mariana Sottomayor
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/EBB-BIO/113116/2009

Improved and faster Virus Based Biopharmaceuticals development: recombinase mediated cassette exchange tools for mammalian cell engineering
Ana Sofia de Sousa Valente Coroadinha
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/EBB-BIO/113123/2009

Characterization of the secretome of mesenchymal stem cells from the umbilical cord blood and matrix and the study of the mechanisms responsible for its effect on survival, differentiation and neural regeneration
MÁRIO MARTINS RODRIGUES GRÃOS
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/EBB-BIO/113139/2009

Aerobic granular sludge for textile wastewater treatment
Nídia Dana Mariano Lourenço
Instituto Superior Técnico (IST/ULisboa)

PTDC/EBB-BIO/113198/2009

BIOPLAT - A NOVEL HIGH-THROUGHPUT PLATFORM FOR THE SYSTEMATIC AND LARGE-SCALE STUDY OF BIOFILMS
Maria Olívia Baptista de Oliveira Pereira
Universidade do Minho (UM)

PTDC/EBB-BIO/113253/2009

Yeast heterologous expression of mammalian aquaporins: screening for compounds of potential pharmacologic use
Maria da GRAÇA Tavares Rebelo de SOVERAL Rodrigues
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/EBB-BIO/113494/2009

BIO.S.A.: A sustainable and integrated bioproduction of succinic acid using renewable feedstocks.
Christophe François Aimé Roca
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/EBB-BIO/113509/2009

Development of strategies to improve monoclonal production in bioreactors
Mariana Contente Rangel Henriques
Universidade do Minho (UM)

PTDC/EBB-BIO/113610/2009

Recombinant defective viral particles as immunogens for a chikungunya virus vaccine
Aida Maria da Conceição Esteves Simões
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/EBB-BIO/113658/2009

STEMSOURCE - Converting Stem Cell Potential into Clinical Applications: Systematic Study of Different Cell Sources
Joao Manuel Teixeira de Oliveira
Universidade do Minho (UM)

PTDC/EBB-BIO/113668/2009

Prevention of biofilm formation and destruction of established biofilms with compounds from aromatic herbs (KillFilm)
Carla da Conceicao Caramujo Rocha de Carvalho
Instituto Superior Técnico (IST/ULisboa)

PTDC/EBB-BIO/113677/2009

Towards the on-line control of antibody glycosylation: a Systems Biology approach
João Miguel Lopes Dias
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/EBB-BIO/113784/2009

GLYCONSTRUCT - Yeast-based technologies for the enzymatic synthesis of glycopeptides with tumor-associated antigens
Pedro Miguel Reis Guimaraes
Universidade do Minho (UM)

PTDC/EBB-BIO/113839/2009

FLOWBEADS - Novel materials for the high-throughput diagnosis of livestock-related infectious diseases
Joao Inacio Silva
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/EBB-BIO/113891/2009

Targeting a combination of gene silencing agents (siRNA) to tumor cells and the tumor microenvironment
João Nuno Sereno de Almeida Moreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/EBB-BIO/114067/2009

Plant laboratory prototype for the production and recovery of recombinant proteins
José Pissarra
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/EBB-BIO/114069/2009

Exploring the Therapeutic Potential of the Secretome of Mesenchymal Stem Cells in Parkinson's Disease
António José Braga Osório Gomes Salgado
Universidade do Minho (UM)

PTDC/EBB-BIO/114288/2009

Ion Jelly® technology as matrix for new biosensors
Cristina Cordas
NOVA.ID.FCT - Associação para a Inovação e Desenvolvimento da FCT (NOVA.ID.FCT)

PTDC/EBB-BIO/114600/2009

Metagenomic survey of acidic, hot springs in the Azores for the discovery of efficient, robust enzymes for conversion of lignocellulosic biomass at high temperature and low pH
Maria Helena Dias dos Santos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/EBB-BIO/114697/2009

Integrated separation and expansion of Human Hematopoietic Stem/Progenitor Cells using Immunomagnetic lipoplexes
Teresa Catarina Páscoa Madeira
Instituto Superior Técnico (IST/ULisboa)

PTDC/EBB-BIO/114919/2009

Biorefining - The use of enzymes in modification of fibres for improving pulp refining
Ana Paula Costa
Universidade da Beira Interior (UBI)

PTDC/EBB-BIO/115094/2009

Novel Plasmodium proteins with diagnostic and therapeutic application in malaria
MARIA DE FÁTIMA CARVALHO NOGUEIRA
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/EBB-BIO/115305/2009

Biochemical and Molecular characterization of a novel ochratoxin A hydrolytic enzyme
Luís Abrunhosa
Universidade do Minho (UM)

PTDC/EBB-BIO/115457/2009

Cellukill - Development of novel antimicrobial bacterial cellulose films: studies on physical, structural, antimicrobial and wound healing properties
Maria Manuela Pintado
Universidade Católica Portuguesa (UCP)

PTDC/EBB-BIO/115514/2009

Generation of new transgenic animals for in vivo tracking of Regulatory T cells
Carlos Eduardo Tadokoro
Fundação Calouste Gulbenkian (FCG)

PTDC/EBB-BIO/115805/2009

Encapsulation of Active Compounds by Spray Drying
Manuel Alvaro Neto Coelho
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/EBB-BIO/116232/2009

FatBacteria - Bioenergy potential of hydrocarbonoclastic bacteria fattened up from polluted (waste)waters
MARIA ALCINA ALPOIM DE SOUSA PEREIRA
Universidade do Minho (UM)

PTDC/EBB-EBI/112170/2009

BCGrafts: Bacterial Cellulose-Made Prosthetic Vascular Grafts
Francisco Miguel Portela da Gama
Universidade do Minho (UM)

PTDC/EBB-EBI/114364/2009

Anaerobic lipids/LCFA conversion in bioreactors: from microbial ecophysiology to enhanced biogas production
Diana Zita Machado de Sousa
Universidade do Minho (UM)

PTDC/EBB-EBI/115810/2009

Unraveling cancer metabolism and tumor growth through flux analysis and metabolic engineering
Rui de Albuquerque Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/EBB-BIO/113576/2009

User-friendly model to simulate single and multi-component biomacromolecule adsorption onto ion-exchange and hydrophobic interaction supports
Ana Cristina Dias Cabral
Universidade da Beira Interior (UBI)

PTDC/EBB-BIO/113671/2009

Skin2Tex Old peptides with new faces: A new strategy to develop non-toxic antimicrobial textiles for healthcare applications.
Isabel Cristina Aguiar de Sousa e Silva Gouveia
Universidade da Beira Interior (UBI)

PTDC/EBB-BIO/114320/2009

Isolation and Purification of Plasmid DNA for Cancer Therapy
João António de Sampaio Rodrigues Queiroz
Universidade da Beira Interior (UBI)

PTDC/EBB-BIO/114523/2009

EpitHope - Advanced Biomimetic Regenerative Strategies for Active Targeting Degenerative Articular Cartilage
Helena Paula de Sousa Sepúlveda Azevedo
Universidade do Minho (UM)

PTDC/EBB-BIO/114760/2009

Development of an anti-pseudomonal product with genetically modified phages to control biofilms formed by Pseudomonas aeruginosa
Sanna Sillankorva
Universidade do Minho (UM)