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R&D Projects

Call for Funding of Research and Development Projects in all Scientific Domains - 2009

Painel de Avaliação da área das Ciências da Saúde - 2009

Coordination

Fernando Lopes da Silva
Center of NeuroSciences - Amesterdão, Netherlands

Evaluation

Ad Geurts van Kessel
Andrew Westwell
Cardiff University, United Kingdom
Bruno Bujoli
Université de Nantes, France
Caetano Reis e Sousa
Cancer Research UK London Research Institute, United Kingdom
Derek Macallan
St George's - University of London, United Kingdom
Fernando Giraldez Orgaz
Geert Martens
Geert van der Heijden
University Medical Center - Utrecht, Netherlands
George Griffin
St. George's - University of London, United Kingdom
Gerard J te Meerman
UHD Mathematische Genetica - Groningen, Germany
Gordon Stewart
University College London, United Kingdom
Humphrey Hodgson
Medical School - UCL - Londres, United Kingdom
Jean Vanderpas
Medical Microbiology Laboratory - Bruxelas, Belgium
Jean-Michel Bouler
University of Nantes, France
John Martin
University College London, United Kingdom
Louis Lemieux
UCL Institute of Neurology - Londres, United Kingdom
Marc Mareel
Ghent University, Belgium
Marc Moreau
Université Paul Sabatier - Toulouse, France
Mark Van de Casteele
Vrije Universiteit Brussel, Belgium
Maurice Zeegers
University of Birmingham, United Kingdom
Maxime GUYE
Université de la Méditerranée, France
Peter Illes
Rudolf-Boehm - Institut für Pharmakologie und Toxikologie der Universität - Leipzig, Germany
Robert Hofstra
University Medical Center Groningen, Netherlands
Roland Pochet
Univ. Libre de Bruxelles, Belgium
Rolf Jackisch
Institute of Experimental and Clinical Pharmacology and Toxicology - Freiburg, Germany
Sergio Cerutti
Polytechnic University of Milan, Italy
Stephen Paul Hilary Alexander
University of Nottingham Medical School, United Kingdom

Projects assigned

PTDC/SAU-GMG/109837/2009

Development of an integrative knowledgebase for medical systems biology
Matthias Erwin Futschik
Universidade do Algarve (UAlg)

PTDC/SAU-GMG/109935/2009

Identification of metabolic networks involved in cellular aging under post-transcriptional regulation by miRNAs
Francisco Javier Enguita
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/110381/2009

Cis- and trans-effects in Machado-Joseph disease: role of CTCF-mediated mechanisms on repeat instability and ATXN3 Like retrogene product as a possible phenotype modifier
Sandra Martins
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-GMG/110599/2009

GARDEN : Genetic variants Association and coRonary Disease risk EvaluatioN
Maria Isabel Sairava de Moura Mendonça
Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação - Associação (ARDITI)

PTDC/SAU-GMG/110669/2009

Uma metodologia para o diagnóstico e prognóstico do cancro da próstata
Maria Carmen Alpoim
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/110788/2009

The role of HFE in iron metabolism regulation in normal and iron overload conditions
MARIA PAULA DUARTE FAUSTINO GONÇALVES
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-GMG/110836/2009

Psychosis: sub-phenotypes, phenotypic dimensions and genetic correlates
António Ferreira de Macedo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-GMG/111237/2009

Development of splicing therapeutics strategies for patients affected by lysosomal storage disorders
Sandra Catarina da Conceição Alves
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-GMG/111265/2009

GEOSITE: Genetic Epidemiology Of Stroke In The post-GWAS Era
Ana Sofia Simões Domingues de Almeida Oliveira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/111295/2009

miRADGE-ID: miRNAs and longncRNAs Deciphering the GEnetics of Mild Cognitive Impairment and Alzheimer's Disease
Madalena Cristina da Rocha Martins
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/111489/2009

Functional assessment of novel malaria parasite mutations involved in resistance to artemisinin derivatives.
Pedro Vitor Lemos Cravo
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-GMG/111778/2009

miRNA and Gene Signaling Networks Regulated by ERK5 in Colon Cancer
Cecília Maria Pereira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/111862/2009

Biomarkers identification of anti-TNF agents efficacy in ankylosing spondylitis patients using a transcriptome analysis and mass spectrometry.
Jaime Branco
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/112122/2009

RNAi SCREEN FOR HOST MOTOR PROTEINS REQUIRED FOR Fc-MEDIATED PHAGOCYTOSIS, SALMONELLA INVASION AND BACTERIAL KILLING
Otília Vieira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-GMG/112146/2009

Clinical, genetic and molecular study of maxillary lateral incisors agenesis
Teresa Pinho
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/112410/2009

Feeding the malaria parasite in the liver: from nutrient uptake and transport to regulation of host cell homeostasis
Miguel Prudêncio
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/112538/2009

Harnessing Genetics and Imaging to Improve Diagnosis and Management of Hypertrophic Cardiomyopathy in Portugal
Alexandra R Fernandes
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-GMG/112645/2009

Quality control of gene expression: nuclear metabolism of the nonsense transcripts
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/112653/2009

Association studies on phenotype and genotype in Essential Tremor: genes and molecular pathways
Gabriel Miltenberger-Miltenyi
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/112828/2009

Molecular genetics of monogenic diabetes due to pancreatic beta-cell defects
Manuel Lemos
Universidade da Beira Interior (UBI)

PTDC/SAU-GMG/112865/2009

Clinical translation of autism genomic findings: validation of whole genome CNV screening for etiological diagnosis.
Astrid Vicente
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/112964/2009

Translational control by an upstream open reading frame in the human erythropoietin transcript
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/113046/2009

Genetic markers and loci associated with disorders of iron metabolism - a comprehensive screening in normal subjects and patients
Licínio Manuel Mendes Manco
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-GMG/113154/2009

Migraine Genetic Study
José Maria Pereira Monteiro
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/113209/2009

EPPICS - Epigenetic mechanisms regulated by serine/ threonine protein phosphatases in the brain - effect on CYP46A1 expression and on other synaptic plasticity-related genes.
Elsa Margarida Teixeira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/113294/2009

mtDNA dysfunction as a biomarker in polyglutamine(poly-Q) disorders: Depletion and damage patterns in Machado-Joseph disease (MJD).
Maria Manuela de Medeiros Lima
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/113385/2009

Patologia Molecular em doentes com Distrofia Muscular de Duchenne (DMD): serão as discrepâncias genótipo-fenótipo moduladas por RNAs não codificantes?
Elsa Maria Ribeiro Bronze da Rocha
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/113440/2009

The role of RNA polymerase II in splicing regulation
Maria Carmo-Fonseca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/113454/2009

Common cancer-predisposing mutations in Portugal: founder effects and associated somatic genetic changes
Manuel António Rodrigues Teixeira
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-GMG/113495/2009

Fatty acid oxidation disorders: from protein misfolding to cellular dysfunction
Cláudio Emanuel Moreira Gomes
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-GMG/113943/2009

Clinical and genetic studies on Charcot-Marie-Tooth disease: an integrated approach to the first Portuguese cohort
Gabriel Miltenberger-Miltenyi
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/114162/2009

Genetics of alcohol dependence: the role of genes from exocytotic machinery
Alda Maria Abreu Cardoso
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/114171/2009

Genetics of Attention deficit/hyperactivity disorder: genes from gabaergic system and phenotype-genotype correlation
Alda Maria Abreu Cardoso
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/114186/2009

The role of filaggrin mutations in the etiology of Atopic Eczema in a Portuguese population
Alberto Joaquim Vieira Mota
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-GMG/114262/2009

Genetic profiling of high grade glioma tumor resistance to temozolomide: insight from 3D model cultures
Joana Paiva Gomes Miranda
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/114270/2009

Dynamics of drug resistance in Chronic Myeloid Leukaemia - emphasis on the role of transporter proteins.
Marta Luísa Gromicho Morgado Silva
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/114316/2009

Comparative genetic study of molecular profiles of atopy and inflammation in young and elderly adults
Luis Manuel Taborda Barata
Universidade da Beira Interior (UBI)

PTDC/SAU-GMG/114348/2009

Cystic Fibrosis: Study of prevalence and analysis of CFTR gene mutations in Portuguese population
Ana Isabel Fernandes Grangeia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-GMG/114742/2009

Neuropsychological Assessment and Dual Genome Investigation in Frontotemporal Dementia
Manuela Grazina
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-GMG/114747/2009

Bigenomic Interaction and Genotype-Phenotype Correlation in Leber´s Hereditary Optic Neuropathy
Manuela Grazina
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-GMG/114916/2009

Modulation of Pyruvare Dehydrogenase Complex: chaperones on the road to novel therapeutic interventions
Isabel Maria Antolin Martins-de-Carvalho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/115229/2009

Gestational diabetes mellitus, newborn birth weight and foetus cardiac septal hypertrophy: a shared genetic susceptibility with type 2 diabetes?
Henriqueta Alexandra Mendes Brêda Lobo Coimbra Silva
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-GMG/115431/2009

Role of polimorphisms of glycoproteins GPIb alpha, GPIIIa and ADP receptor in antiplatelet therapy response
Maria do Céu Rodrigues Monteiro
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-GMG/115652/2009

Super-resolution Imaging of Gene Expression & Nuclear Architecture
Musa M. Mhlanga
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/115672/2009

Genetic Modulation of Adrenal Androgens as a Cause of Polycystic Ovary Syndrome
Duarte Luis Pignatelli Dias Almeida
Hospital de São João EPE (HSJ)

PTDC/SAU-GMG/115931/2009

Early biomarker discovery for hepatocellular carcinoma
Deborah Penque
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-MIC/109786/2009

HIV/AIDS: contribute of naïve CD4 T cell homeostasis
Ana Espada de Sousa
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/109866/2009

Identification and characterization of novel virulence proteins of Chlamydia trachomatis
Luís Jaime Gomes Ferreira da Silva Mota
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MIC/110266/2009

Characterization of infectious agents in peritoneal dialysis patients
Isabel João Soares da Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MIC/110316/2009

Mechanism and consequences of an IL-8 inducing herpesvirus gene
Michael Parkhouse
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MIC/110379/2009

Discovering host genes that control Plasmodium development in hepatocytes
CARLOS AUGUSTO GOMES BARBOSA DA PENHA GONÇALVES
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MIC/110445/2009

Correlation between CD-associated risk loci and susceptibility to MAP infection
Amélia Maria Marques da Silva Rodrigues Sarmento Assunção
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MIC/110535/2009

Molecular and Cellular Mechanisms of Anaemia of Chronic Infection
Maria Salomé Gomes
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MIC/110608/2009

Role of endogenous haem production in the survival of the human pathogen Staphylococcus aureus
Ligia M Saraiva
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MIC/110754/2009

MRPs (Multidrug Resistance Proteins) in Plasmodium falciparum - factors in artemisinin combination therapy (ACT) resistance
Jose Pedro Blanco Panadés Gil
Universidade do Algarve (UAlg)

PTDC/SAU-MIC/110887/2009

Pathogenesis of gamma-herpesvirus: modulation of the cellular transcription factors NF-kB and MYC
João Pedro Monteiro e Louro Machado de Simas
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/111331/2009

Evaluation of neurocognitive deficits due to malaria infection: an approach using rodent models
Ana Margarida Aires Alves Vigário
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/111447/2009

Response to oxidative and nitrosative stress by Entamoeba histolytica: searching for new virulence factors
João Filipe Bogalho Vicente
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-MIC/111486/2009

Exploring the contribution of new genetic markers of drug resistance in human malaria parasites
Pedro Vitor Lemos Cravo
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/111500/2009

New and faster diagnostic tools for detection of antifungal resistance in relevant clinical moulds
Ricardo Jorge Pinto Araujo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-MIC/111548/2009

HCV-specific immune response in hepatitis C chronically infected patients during antiviral therapy: association of HCV-specific CD8+ T cells and dendritic cells responses to the outcome to therapy
Paula Cristina Santos Luxo Maia
Universidade de Coimbra (UC)

PTDC/SAU-MIC/111726/2009

Molecular mechanisms of antifungal drug resistance in fungal pathogens
Luís André Vale Silva
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-MIC/111910/2009

Biomarkers to evaluate persistency of Mycobacterium tuberculosis clones within different human populations
Susana David
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MIC/111916/2009

PATH - Preparation of Antimicrobials Targeting Human-pathogens
Susana Isabel Fonseca de Almeida Santos Braga
Universidade de Aveiro (UA)

PTDC/SAU-MIC/111917/2009

Study of inhibitory effect from different Apobec family proteins against HIV-2 Vif
Isabel Maria Corrêa Calvente de Barahona
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-MIC/111934/2009

Molecular mechanisms of azole drug resistance in Aspergillus species.
Joao Pedro Silva Frade
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MIC/111949/2009

Comparative study of antimicrobial resistance in Staphylococcus aureus, Escherichia coli and Enterococcus spp. isolated from humans, their pets (dog and cat) and home environment
Paulo Manuel Rodrigues Martins da Costa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-MIC/112398/2009

The action mechanism of Blad: A differential polypeptide approach to fight human fungal pathogens
Sara Alexandra Valadas da Silva Monteiro
Instituto Superior de Agronomia (ISA/ULisboa)

PTDC/SAU-MIC/112590/2009

Identification of Cross-neutralizing epitopes in the transmembranar region of HIV-1 and HIV-2: contributions to the development of an HIV vaccine
Helena Barroso
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MIC/112661/2009

Hepatitis C virus-specific CD8+ T cells response during pegylated interferon alpha and ribavirin treatment in HCV-HIV-1 coinfected patients: association to the outcome of therapy.
Paula Cristina Santos Luxo Maia
Universidade de Coimbra (UC)

PTDC/SAU-MIC/113059/2009

Host-induced changes in Aspergillus fumigatus exoglycome. Search for specific targets with potential for clinical therapies and/or diagnosis
Ricardo Manuel de Seixas Boavida Ferreira
Instituto Superior de Agronomia (ISA/ULisboa)

PTDC/SAU-MIC/113146/2009

Mechanisms triggered by Brugia malayi to modulate host defenses and cause infection: identification of new therapeutic targets
Sandra Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MIC/113169/2009

The LIPI-3 Listeria monocytogenes stress response and virulence
Maria Leonor Faleiro
Universidade do Algarve (UAlg)

PTDC/SAU-MIC/113225/2009

Screening of chromatin factors involved in antigenic variation in Trypanosoma brucei
Luisa M Figueiredo
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/113274/2009

Genomic diversity and virulence analysis of Mycobacterium tuberculosis strains of family Lisboa
Isabel Portugal
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MIC/113508/2009

CGB - Candida glabrata biofilms: mechanisms of tolerance to antifungal agents
Mariana Contente Rangel Henriques
Universidade do Minho (UM)

PTDC/SAU-MIC/113604/2009

Antigenemia test for diagnosis of acute phase chikungunya virus infection
Aida Maria da Conceição Esteves Simões
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/113697/2009

Mechanisms of Plasmodium liver infection: Subverting the host ubiquitin-proteasome pathway towards an immune evasion strategy
Vanessa Zuzarte Luis
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/113871/2009

The prevalence of Borrelia infections in cutaneous B cell lymphomas in Portugal
António Medina de Almeida
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-MIC/113925/2009

Non-Candida albicans Candida (NCAC) virulence factors triggered by host-pathogen interactions
Joana Cecília Valente Rodrigues Azeredo
Universidade do Minho (UM)

PTDC/SAU-MIC/114198/2009

Efficacy of echinocandins (anidulafungin and caspofungin) in the treatment of Pneumocystis pneumonia in the mice model.
Olga Maria Guerreiro de Matos
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/114714/2009

Identifying the molecular patterns of Chlamydia trachomatis Orphan genes: a step forward to deciphering their biological role
JOÃO PAULO DOS SANTOS GOMES
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MIC/114842/2009

New strategies to control S. epidermidis biofilms
Maria do Pilar de Araújo Teixeira
Universidade do Minho (UM)

PTDC/SAU-MIC/115173/2009

Application of Giardia-specific FABP proteins to the immunodiagnostic and therapeutic control of giardiasis
Maria do Céu Rodrigues de Sousa
Universidade de Coimbra (UC)

PTDC/SAU-MIC/115178/2009

Pathways proteomics in Leishmania: Mapping the functional proteome towards novel therapeutic opportunities
Carlos Cordeiro
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-MIC/115301/2009

Filamentous bacteriophages and pathogenecity factors of Neisseria meningitidis, from a collection of invasive strains and isolates from asymptomatic carriers (FILPHAGE)
Mário Manuel do Carmo de Almeida Santos
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-MIC/115312/2009

Proteomic approach to host-pathogen interactions in Mediterranean spotted fever
Rita De Sousa
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-MIC/115403/2009

Genetic linkage of resistance and virulence determinants in uropathogenic Klebsiella pneumoniae and Escherichia coli isolates from community-acquired urinary tract infections
Aida Duarte
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-MIC/115843/2009

Characterization and analysis of molecular evolutionary mechanisms associated with the development of influenza virus resistance to neuraminidase inhibitor antiviral drugs
Helena Rebelo-de-Andrade
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MIC/116048/2009

Programmed cell death induced by different (sub)types of influenza viruses (seasonal and pandemic): implications on the replication cycle and infectiousness
Helena Rebelo-de-Andrade
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-IMU/110303/2009

Role of newly identified genes in in vivo antigen cross-presentation-dependent generation of CTL responses against tumors
LUÍS FILIPE FERREIRA MOITA
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/110336/2009

B1 cells and natural antibodies as main players on type 1 diabetes early steps
CARLOS AUGUSTO GOMES BARBOSA DA PENHA GONÇALVES
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-IMU/110380/2009

Pregnancy-associated malaria in the mouse: resolving Plasmodium berghei adhesion, dissecting fetal factors and defying immuno-protection.
CARLOS AUGUSTO GOMES BARBOSA DA PENHA GONÇALVES
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-IMU/110600/2009

miRNAs: key regulators of immune response in Alzheimer's disease
Ana Luísa Colaço Cardoso
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-IMU/110906/2009

Cytotoxic T lymphocyte response to latent infection.
Sofia Marques
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/110916/2009

Role of CD38 and NAD metabolism in immune regulation and development of autoimmune diseases
Teresa Maria Caldeira Martins
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-IMU/110963/2009

Controlo da resposta T para os monócitos.
Elisabetta Padovan
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-IMU/111132/2009

Study on ontogeny, molecular markers and factors of CD8+ T suppressor cells
Elsa Maria Pereira de Oliveira Cardoso
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-IMU/111465/2009

The Role of Retinoic Acid in the thymic generation of Regulatory T cells
Carlos Eduardo Tadokoro
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-IMU/111497/2009

Inflammation in zebrafish: in vivo study of the role of chemokine networks in neutrophil and macrophage migration.
Angelo Miguel Silva Calado
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/111540/2009

Confocal Endomicroscopy in Inflammatory Bowel Disease
PEDRO MANUEL NARRA DE FIGUEIREDO
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-IMU/111551/2009

Antibodies towards high density lipoprotein (HDL) components are associated with modifications in the anti-atherogenic properties of HDL
José Delgado Alves
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-IMU/111654/2009

Role of chemokine receptor expression in T cell repopulation following lymphopenia.
Afonso Rocha Martins de Almeida
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/111806/2009

Small immunoactive peptidoglycan (siPGN) derivatives to modulate an host inflammatory response
Sérgio Joaquim Raposo Filipe
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-IMU/111869/2009

Regulation of B cell function and terminal differentiation during the immune response by reactive oxygen spieces.
Maria Margarida Souto Carneiro
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-IMU/112325/2009

Modulation of dendritic cell phagocytosis by sialic acids: a mechanism that subverts maturation-induced loss of endocytic capacity
Paula Alexandra Quintela Videira
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-IMU/112543/2009

Study of the changes in the human T cell immunity induced by the treatment with polyclonal immunoglobulin
Cristina Maria Godinho Pires João
Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE (IPO Lisboa)

PTDC/SAU-IMU/113032/2009

A ectoenzima CD38: papel nas infecções por micobactérias.
Marta Susana de Almeida Viegas da Silva
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-IMU/113541/2009

Cellular and molecular requirements in human Regulatory T cell development
Iris Caramalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/113767/2009

Characterization of the immune response to Norovirus infection towards a vaccination protocol
Luzia Manuela Lima Teixeira Ranginha
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-IMU/113987/2009

Immunoregulatory and inflammatory properties of transfusional red blood cell units in vitro.
Fernando Aguilar Arosa
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-IMU/114532/2009

IMMUNOGENIUS - Immunogenic potential of amniotic membrane- and starch-based tissue engineering constructs
Alexandra P Marques
Universidade do Minho (UM)

PTDC/SAU-IMU/115161/2009

VALUE OF FLOW CYTOMETRY IN THE DIAGNOSIS AND STUDY OF THE BIOLOGY AND EVOLUTION OF MEMBRANE ERYTHROCYTE DISORDERS
MARGARIDA LIMA
Centro Hospitalar Universitário do Porto (CHP/MS)

PTDC/SAU-IMU/115270/2009

Functional Significance of TGF-beta-Driven Plasticity of Invariant Natural Killer T Cells
Marta Sofia Ferreira Monteiro Coelho Antunes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/115331/2009

Evaluation of the adaptative immunity imbalance in progression of acute myocardial infarction
MIGUEL ADRIANO BENTO MOTA CARMO
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-IMU/115948/2009

Evolution of the Immunological profile in the offspring of atopic and healthy women, during the first two years of life
Luis Miguel Nabais Borrego
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-NMC/109789/2009

Hypothalamic (dys)function upon opioid dependence and substitution treatment
MARIA TERESA MARTINS DA CUNHA OLIVEIRA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/109790/2009

Effects of chronic exposure to cocaine-opioid combinations
Catarina Oliveira
Universidade de Coimbra (UC)

PTDC/SAU-NMC/110219/2009

Modulation of neurodegeneration and neuroinflammation by Annexin A1 in experimental models of Parkinson's disease
Margarida Casal Ribeiro Castro Caldas Braga
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/110225/2009

Endocannabinoids as modulators of neurogenesis in the intact and damaged brain: role of hemoglobin-derived peptides
Sara Xapelli
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/110507/2009

Identifying axonal regeneration enhancers
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/110573/2009

Modulating Factors in the Transthyretin/A-Beta peptide interaction
Isabel dos Santos Cardoso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/110809/2009

Control of neuronal signaling pathways by CYP46A1, an enzyme involved in brain cholesterol turnover
Elsa Margarida Teixeira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/110835/2009

Changes in GABAergic synaptic transmission in brain ischemia
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/110838/2009

Modulation of GABAergic transmission in the hippocampus by adenosine
Ana Maria Ferreira Sousa Sebastião
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/110993/2009

Deciphering the role of Abeta toxicity in the loss of endogenous neuroprotection
Maria José de Oliveira Diógenes Nogueira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/111135/2009

Study of the effects of inhibitors of protein aggregation on TTR amyloidogenesis
Maria Rosário Almeida
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/111312/2009

Role of growth factors in neuroprotection in the central nervous system
Maria João Gameiro de Mascarenhas Saraiva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/111342/2009

Small RhoGTPase RhoA in brain ischemia - a functional study
Sofia Santos
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/111388/2009

Meningitis caused by Group B Streptococcus: the use of a novel experimental model mimicking the natural route of infection in humans to study the mechanisms of brain damage induced by this bacterium
Paula Ferreira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/111429/2009

Understanding the impact of methamphetamine on the adult hippocampal neurogenesis: new insights for memory recovery
Ana Paula Pereira da Silva Martins
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-NMC/111529/2009

Interplay between endothelial cell dysfunction and hippocampal neurodegeneration in Alzheimer's disease: a molecular therapeutic target for new bioactive estrogen derivatives
Cláudia Maria Fragão Pereira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/111705/2009

The role of sirtuins in the cross-talk between inflammation and neurodegeneration in synucleinopathies .
Maria Teresa Albuquerque Santos Faria Pais
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/111996/2009

Function of the orexigenic peptide ghrelin in the hippocampus
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/112091/2009

Mitochondrial signalling pathway in Alzheimer's disease: disclosure of therapeutic targets
Sandra Morais Cardoso
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/112243/2009

Modulation by adenosine receptors of the protective and deleterious roles of astrocytes
PAULA MARIA GARCIA AGOSTINHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/112369/2009

Carbon monoxide: novel strategies to stimulate neurogenesis in vivo and to improve neuronal differentiation of human embryonic carcinoma stem cells in vitro
Helena Luisa de Araujo Vieira
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-NMC/112536/2009

Involvement of autophagy and effects of its modulation in Machado-Joseph disease pathogenesis
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/112565/2009

Unravelling the role of ATF-3 expression in primary afferents during inflammatory pain
Fani Lourença Moreira Neto
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/112636/2009

Modulation of amyloid beta-induced neuronal toxicity via JNK: a novel role for tauroursodeoxycholic acid
Rita Cruz Coelho de Mira Ramalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/112853/2009

Amylin's role in nociception: a comprehensive study in multiple pain models
Fani Lourença Moreira Neto
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/112892/2009

Modulation of glycinergic transmission in hippocampus - function in epilepsy
Cláudia Alexandra dos Santos Valente de Castro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/112991/2009

Neurotrofinas: elementos chave no síndrome da bexiga hiperactiva?
Célia da Conceição Duarte Cruz
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/113113/2009

A novel class of lamina I neurons with extensive local axon collaterals: intersegmental distribution of local and descending input
Peter Szucs
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/113163/2009

Mechanisms of action of Botulinum toxin in the treatment of benign prostate hyperplasia
António Avelino Ferreira Saraiva da Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/113180/2009

Uncovering the neuroprotective role of adenosine in diabetic retinopathy
Paulo Fernando Martins dos Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/113256/2009

Protein aggregate formation, dynamics and clearance in neurodegenerative disorders: parkin and PKCgamma mutants as a model
Isabel Alonso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/113343/2009

Phosphorylation pathways involved in the oligomerization and toxicity of mutant huntingtin
Federico Herrera
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/113346/2009

Impact of ecstasy on neural retina and blood-retinal barrier: the first real look!
António Francisco Rosa Gomes Ambrósio
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-NMC/113464/2009

O peixe Zebra como um novo organismo-modelo na doença de Parkinson
Ana Dulce de Ascensao Almeida Correia
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/113554/2009

BDNF effect on cytoskeleton and plasma membrane lipid dynamics during neuronal differentiation
BRUNO JOSÉ FERNANDES OLIVEIRA MANADAS
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/113626/2009

Influence of nutrition in cellular signalling systems related to oxidative stress and neuronal survival in the Rat hippocampal formation
José Paulo Alves Vieira de Andrade
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/114007/2009

Voltage-sensitive Ca2+ channels and/or Ca2+-activated K+ channels as early glucose sensors in pancreatic beta-cells
Luís Martinho do Rosário
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/114040/2009

Gstpi at the Crossroad of UPS and Autophagy Avenues
Maria João Carlos da Silva Gama
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/114044/2009

Interaction between endoplasmic reticulum stress-mediated endothelial dysfuntion and hippocampal neurogenesis. Potential therapeutic target for the treatment of neurodegenerative disorders
Elisabete Ferreiro
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/114213/2009

The neurobiology of depression: molecular signaling and cell cycle regulation by depression and antidepressant drugs
Luisa Pinto
Universidade do Minho (UM)

PTDC/SAU-NMC/114220/2009

How do the barriers of the brain modulate aging and contribute to Alzheimer's disease? A study on the choroid plexus/cerebrospinal fluid nexus.
Joana de Almeida Santos Pacheco Palha
Universidade do Minho (UM)

PTDC/SAU-NMC/114370/2009

INFLUENCE OF ESTROGENS IN THE RESPONSE OF THE HYPOTHALAMO-PITUITARY-ADRENAL AXIS TO ACUTE STRESSORS DURING ALCOHOL CONSUMPTION AND WITHDRAWAL
Maria Dulce Cordeiro Madeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/114672/2009

Role of S100B in the myelination and remyelination of the central nervous system: a cytoskeletal perspective
Adelaide Fernandes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/114935/2009

Unraveling the molecular mechanisms behind striatal-dependent behaviors
Domingos Manuel Pinto Henrique
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/114948/2009

Purinergic modulation of fast neurotransmitter release machinery.
Joao Miguel da Silva Cordeiro
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-NMC/115097/2009

Excitotoxic signalling through Ca2+-permeable AMPA receptors: pinpointing new therapeutic targets
Armanda Emanuela Castro e Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/115227/2009

Mechanisms of regulation of the proteasome under excitotoxic conditions
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NSC/109771/2009

Optical Quality of Vision using Hyperspectral Wavefront Analysis in Refractive and Cataract Surgery
Paulo Torrão Fiadeiro
Universidade da Beira Interior (UBI)

PTDC/SAU-NSC/110210/2009

When do genes and environment meet to cause schizophrenia: regulating cerebrospinal fluid dynamics?
Joana de Almeida Santos Pacheco Palha
Universidade do Minho (UM)

PTDC/SAU-NSC/111367/2009

Enhancing Prospective Remembering through Enactment in Healthy and Impaired Older Adults
Manuela Guerreiro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NSC/111550/2009

The interplay between astrocytes and neurons in the progression of stress-induced cognitive disorders
João Filipe Oliveira
Universidade do Minho (UM)

PTDC/SAU-NSC/111616/2009

Cognitive Involvement in Multi-systemic Autoimmune Diseases
Sara Marta Pereira dos Santos Cavaco
Centro Hospitalar Universitário do Porto (CHP/MS)

PTDC/SAU-NSC/111914/2009

The ERKs pathway and the monoaminergic system in chronic pain and depression
Fani Lourença Moreira Neto
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NSC/111978/2009

Damage of Primary Afferent Neurons Associated With Experimental Osteoarthritis
José Manuel Pereira Dias de Castro Lopes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NSC/112052/2009

Robust localization of epileptic foci in the first years of life by the multimodal integration of EEG and the hemodinamic response.
Alberto João Rodrigues Leal
Centro de Investigação e Intervenção Social (CIS/ISCTE)

PTDC/SAU-NSC/112147/2009

Fast fMRI
Andreas Miroslaus Wichert
Instituto de Engenharia de Sistemas e Computadores, Investigação e Desenvolvimento em Lisboa (INESC-ID/INESC/IST/ULisboa)

PTDC/SAU-NSC/113068/2009

Etiology of suicide in Portugal: Identification of new genetic risk factors
Alda Maria Abreu Cardoso
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-NSC/113131/2009

Evaluation of a sensitive period for motor skill learning in laboratory mice
Joana Margarida da Silva Marques
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NSC/113159/2009

Insights into Fabry disease: From mice to man, differences and similarities.
Maria Clara Pereira de Sá Miranda
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NSC/113280/2009

Cardiovascular and nociceptive central control. Study of the endogenous association and its mechanisms.
António Albino-Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NSC/113458/2009

Hippocampal metabolic abnormalities in pre-clinical stages of Alzheimer's disease
Rui de Albuquerque Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NSC/113713/2009

Neural mechanisms underlying perceptual decision and sensorimotor integration: from 2D and 3D perception to action
Miguel de Sá e Sousa de Castelo Branco
Universidade de Coimbra (UC)

PTDC/SAU-NSC/113758/2009

Neural mechanisms of associative memory: the role of the interaction between multiple memory systems
Marta de Aragão Pacheco Moita
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/113799/2009

Optogenetic control of 5-HT release, testing the aversion hypothesis
Guillaume Dugué
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/113806/2009

An 8-Week Study of Rhodiola rosea Augmentation of Antidepressants: Sleepiness, Cognitive Symptoms And/Or Fatigue in Depression
Gustavo Kinrys
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/SAU-NSC/113915/2009

How much does your pain hurt me? Neural correlates of empathy for physical and social pain: An fMRI Study
Ana Maria Abreu
Universidade Católica Portuguesa (UCP)

PTDC/SAU-NSC/114481/2009

Traumatic versus diabetic neuropathy: are the structural changes induced in the brain the same and can they be reverted with antidepressants?
Armando Almeida
Universidade do Minho (UM)

PTDC/SAU-NSC/114558/2009

Behavioural intervention on infant´s sleep
Maria Helena Pinto Azevedo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NSC/115045/2009

Dissecting the molecular and circuit bases of intention
Rui Costa
Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (FC Champalimaud)

PTDC/SAU-NSC/115068/2009

Codification of Visual Information in Multiple Sclerosis: Structural, Functional and Cognitive Analysis
PEDRO MONTEIRO
Universidade da Beira Interior (UBI)

PTDC/SAU-NSC/115132/2009

Happiness, emotions and pain perception in chronic rheumatic diseases
Jose Antonio Pereira da Silva
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NSC/115314/2009

Calorie Restriction, Longevity and Sensorymotor Behaviour
Agavni Petrosyan
Universidade do Minho (UM)

PTDC/SAU-NSC/115834/2009

A molecular link between pain and Alzheimer´s disease at the clinic: the potential role of kyotorphin derivatives
Miguel Castanho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NSC/116150/2009

Mathematical processing of biological signs for the analysis of autonomic nervous system function in patients with orthostatic intolerance
Jose Luis Bliebernicht Ducla Soares
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-BMA/109886/2009

Skin2: a biosynthetic second skin, engineered to treat severe burn wounds
Jorge Alexandre Monteiro de Carvalho e Silva
NOVA.ID.FCT - Associação para a Inovação e Desenvolvimento da FCT (NOVA.ID.FCT)

PTDC/SAU-BMA/109912/2009

CONTACT-TEARS: CONTROLLED DELIVERY OF NATURAL BIOCHEMICAL AGENTS AND DRUGS FOR STIMULATION OF TEAR SECRETION
JOSÉ MANUEL GONZÁLEZ MÉIJOME
Universidade do Minho (UM)

PTDC/SAU-BMA/109947/2009

Development of new hydrogels cointaining growth factors for future application as wound dressing systems
Ilídio Joaquim Sobreira Correia
Universidade da Beira Interior (UBI)

PTDC/SAU-BMA/110034/2009

Development of a wound dressing for the treatment of diabetic foot ulceration
Ermelindo Carreira Leal
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-BMA/110044/2009

Modulate physicochemical properties of biopolymers-based nanoparticles by screening its take up by MPS
António José Ribeiro
Universidade de Coimbra (UC)

PTDC/SAU-BMA/111001/2009

NSCgel - Molecularly-designed hydrogels for neural stem cell transplantation and regeneration of severed neurons: a novel combinatorial approach to create a permissible environment for regeneration in the spinal cord.
Isabel Freitas Amaral
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/111063/2009

Bioresponsive peptide-protein conjugates: nanomedicines for tissue repair.
Patricia Ferreira da Luz Pereira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BMA/111286/2009

CROSSTALK - Intercellular communication for angiogenesis stimulation in bone regeneration
Raquel Soares
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-BMA/112609/2009

Multifunctional hybrid nanocomposite surface for neural interfaces
Ana Paula Piedade
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-BMA/112731/2009

Nanotechnological approaches for the development of a new human telomeric DNA electrochemical biosensor for screening anti-cancer drugs
Ana Maria Chiorcea Paquim
Instituto Pedro Nunes - Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia (IPN)

PTDC/SAU-BMA/112889/2009

TUMORTAG - Tumor-targeted nanoparticles for early diagnosis of gastric cancer
Pedro Lopes Granja
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/112922/2009

SURFCELL: Design of surfaces for investigating the communication between bone related cells and their environment
Iva Pashkuleva
Universidade do Minho (UM)

PTDC/SAU-BMA/112959/2009

Resveratol nanocarriers to modulate the immune response in inflammatory arthritis.
Susana Gomes dos Santos
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/112966/2009

Green and biomimetic strategies for the development of silica-based composite materials for biomedical and tissue engineering applications
Hermínio José Cipriano de Sousa
PRODEQ - Associação para o Desenvolvimento da Engenharia Química (PRODEQ)

PTDC/SAU-BMA/113042/2009

Crossed Thermal Therapy of Tumours
Jose Roberto Tinoco Cavalheiro
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/113135/2009

Natural Active Membranes to guided tissue regeneration
Jose Roberto Tinoco Cavalheiro
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/113990/2009

Bacterial cellulose as a potential scaffold for tissue engineering of small intestine
Fernando Octávio de Queirós Dourado
Universidade do Minho (UM)

PTDC/SAU-BMA/114075/2009

DendriThera: Multi-functional dendrimeric macromolecules with applications in theranostics of smooth muscle diseases.
Joaquim Miguel Antunes Correia de Oliveira
Universidade do Minho (UM)

PTDC/SAU-BMA/114195/2009

Design, synthesis and characterization of innovative nanosystems for targeted delivery of anticancer drugs
MARLENE SUSANA DIONISIO LÚCIO
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-BMA/114345/2009

Pharmacologically active bioadhesive designed for wound closure
Paula Cristina Nunes Ferreira
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-BMA/114585/2009

ChronicMat- biodegradable hydrogels to improve the healing of chronic wounds
Simone Silva
Universidade do Minho (UM)

PTDC/SAU-BMA/114960/2009

Targeted photodynamic therapy for prostate cancer: a novel approach for an unmet medical need
João Nuno Sereno de Almeida Moreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-BMA/115813/2009

Treatment of acute pulmonary oedema - development of a new technique using giant unilamellar liposomes
Ana Cristina Aguiar dos Santos
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-BMA/116086/2009

InSituScaf- Natural-origin smart scaffolds with the ability of in situ formation of pores: a novel strategy for bone tissue engineering and regenerative medicine
Ana Margarida Martins de Sousa
Universidade do Minho (UM)

PTDC/SAU-BMA/116174/2009

CAPSUL - Novel hollow nano/micro capsules for drug/gene/cell delivery
Helena Maria Pires Gaspar Tomás
Universidade da Madeira (UMA)

PTDC/SAU-BMA/116220/2009

Development of drug delivery systems in dental root canal sealers
Ana Paula Valagão Amadeu do Serro
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-BMA/116266/2009

3DBioChips - Combinatory Cell-3DBiomaterials Interactions Screening for tissue engineering using biomimetic polymeric substrates
Joao Filipe Colardelle da Luz Mano
Universidade do Minho (UM)

PTDC/SAU-ENB/109775/2009

Displacement-frequency transform applied to Doppler Ultrasound blood flow signals
Ana Isabel Pereira Martins Leiria
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/109899/2009

Extraction of quantitative features from mammary lesions in elastografy images
Ana Isabel Pereira Martins Leiria
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/110175/2009

Computational multiscale simulation of bruxism
Renato Manuel Natal Jorge
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ENB/110351/2009

Optimization of cadaveric embalming via dedicated perfusor development
Paulo António Ribeiro
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FCTUNL/UNL)

PTDC/SAU-ENB/110687/2009

FCMotor: Functional Markers of motor brain activity through synchronous Video-EEG-fMRI methods in health and neurodegenerative diseases
José Maria Fernandes
Universidade de Aveiro (UA)

PTDC/SAU-ENB/110918/2009

Rehabilitating and home-monitoring people with Chronic Obstructive Pulmonary Disease and their families during long term therapy
Alda Marques
Universidade de Aveiro (UA)

PTDC/SAU-ENB/111006/2009

Speech Production and Perception in Hearing Impaired Children
Luís Miguel Teixeira de Jesus
Universidade de Aveiro (UA)

PTDC/SAU-ENB/111352/2009

Non-invasive Dental Imaging and Sensing by Optical Fibers (NIDISOF)
António Lobo Ribeiro
Fundação Ensino e Cultura Fernando Pessoa (FECFP)

PTDC/SAU-ENB/111491/2009

CellNote - Automatic Analysis of Cell Images
Pedro Manuel da Silva Quelhas
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-ENB/111702/2009

miPS and hiPS: reprogramming mouse and human adult cells
José Bragança
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/111844/2009

Experimental and Computational Analysis of Vascular Biomechanics
Lúcia Maria de Jesus Simas Dinis
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ENB/111941/2009

ShockCalc - Comportamento mecânico de cálculos salivares. Resistência a ondas de choque
Patricia Maria Cristovam Cipriano Almeida de Carvalho
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-ENB/111957/2009

Bionanotechnology and proteomics in diabetic skin wound healing: unraveling neuropeptide therapeutics
Daniel Omar Espinoza
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ENB/112069/2009

Biomecânica em Oncologia Ginecológica: uma abordagem multiescala e clínica
Renato Manuel Natal Jorge
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ENB/112247/2009

Identification and characterization of epileptogenic biomarkers in patients with traumatic brain injury using advanced magnetic resonance imaging techniques
HUGO ALEXANDRE TEIXEIRA DUARTE FERREIRA
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ENB/112294/2009

Noninvasive dynamic neuroimaging in epilepsy
Patrícia Figueiredo
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-ENB/112306/2009

Identification of biomarkers in Huntington disease: application of machine-learning pattern classification algorithms to structural and functional magnetic resonance imaging
Gina Maria Costa Caetano
Universidade de Coimbra (UC)

PTDC/SAU-ENB/112327/2009

Automatic Identification of Congenital Heart Defects
JOSÉ SILVESTRE SERRA DA SILVA
Associação para o Desenvolvimento do Departamento de Física da Universidade de Coimbra (ADDFUC/FCT/UC)

PTDC/SAU-ENB/112501/2009

Assessment of bone biomechanical properties and bone quality: identification of a fracture risk cut-off for clinical, diagnostic and therapeutic applications
Helena Canhão
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ENB/112601/2009

Fluid-structure analysis of large arteries in human body
Maria Helena Freitas Melão Barros Gomes Pereira
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-ENB/112931/2009

Hemodisk - Hemorheology on a disk
Maria Carlota Saldanha Lopes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ENB/113271/2009

Positron Emission Tomography with Copper-64: new opportunities for diagnosis, quality control enhancement and cost reduction
Ana Cristina Fidalgo Palma Fernandes
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-ENB/113311/2009

Time-frequency analysis methods to quantify the time-varying microstructure of sleep EEG spindles
Manuel Duarte Ortigueira
Instituto de Desenvolvimento de Novas Tecnologias (UNINOVA)

PTDC/SAU-ENB/114157/2009

VitalWear - Wearable Vital Signs Diagnostic and Monitoring System
Lino Figueiredo
Instituto Superior de Engenharia do Porto (ISEP/IPP)

PTDC/SAU-ENB/114221/2009

A novel gene therapy approach for the treatment of retinal neovascularization
Gabriela Araújo da Silva
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/114360/2009

NECTools: Neuro-Engineering computational tools for brain activity decoding associated with executive function
ANA MARIA PERFEITO TOMÉ
Universidade de Aveiro (UA)

PTDC/SAU-ENB/114531/2009

Atomic force microscopy-based molecular recognition of fibrinogen receptors in platelets and erythrocytes. Applications in Health and Disease
Nuno Fernando Duarte Cordeiro Correia dos Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ENB/114538/2009

fluolifeTomo - Development of a fluorescence lifetime tomograph for small animal imaging
Antonio Miguel Lino Santos Morgado
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ENB/114566/2009

Smart contrast agent for MR Imaging (Cancer early detection)
Fouzi Mouffouk
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/114606/2009

ADIAR - Alzheimer Disease: Image Analysis and Recognition
Margarida Silveira
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-ENB/114614/2009

Blood-on-chips - Towards an understanding of the cell-free layer (CFL) in blood-on-chip devices
Rui Lima
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-ENB/114650/2009

Study of the effects of oclusal forces in the Tempero Mandibulat Joint (TMJ) and in the mandibular and maxillary dental arches
Maria João Pascoal Rodrigues César Machado
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-ENB/114651/2009

Monte Carlo determination of radiation induced second cancer risk for patients undergoing radiation therapy.
GRISEL MARGARITA MORA PAULA
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ENB/114849/2009

Femoroacetabular impingement: in vivo human osteoarthritis model
Jacinto Manuel de Melo Oliveira Monteiro
Faculdade de Medicina da Universidade de Lisboa (FM/ULisboa)

PTDC/SAU-ENB/115112/2009

CASS - Clinical Anatomy of Sacral Stimulation: development of a 3D model as a tool to optimize the technical procedure of sacral nerve stimulation.
Maria Amélia Duarte Ferreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ENB/115172/2009

Continuous-time registration and simultaneous correction for motion and attenuation in emission tomography
Francisco José Santiago Fernandes Amado Caramelo
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ENB/115224/2009

Intelligent Support System for CVA Diagnosis by Cerebral Computerized Tomography
Antonio Ruano
Associação Algarve STP - Parque de Ciência e Tecnologia do Algarve (ASTP)

PTDC/SAU-ENB/115234/2009

AddCart - Development of autologous tissue engineering therapies for the regeneration of cartilage tissue defects based on adipose derived stem cells and platelets lysates hydrogels
Maria Manuela Estima Gomes
Universidade do Minho (UM)

PTDC/SAU-ENB/115287/2009

SeCol - Automatic Detection and Segmentation of Cortical Lesions in Multiple Sclerosis
Carlos Manuel Gregorio Santos Lima
Universidade do Minho (UM)

PTDC/SAU-ENB/115524/2009

HYPERHIFU - Hyperthermia HIFU systems' characterization for cancer therapy.
Maria da Graça Cristo dos Santos Lopes Ruano
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/115572/2009

HydroDISC - Novel injectable biomaterials for the regeneration and repair of the degenerated intervertebral disc
Rui L Reis
Universidade do Minho (UM)

PTDC/SAU-ENB/115574/2009

FibrousBone - Highly functional biodegradable hierarchical structures for bone tissue engineering applications
Nuno Neves
Universidade do Minho (UM)

PTDC/SAU-ENB/115787/2009

Effects of the orthodontic movement induced by sliding forces released with self-ligating and non self-ligating devices on the periodontal ligament - simulation by finite elements and experimental study in vivo
Sérgio Miguel Andrade de Matos
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-ENB/115937/2009

Advanced Molecular Imaging Techniques and Radiobilogical Modelling in the External Beam Radiotherapy Outcome Evaluation
João António Miranda dos Santos
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ENB/116093/2009

IndPCell- Efficient osteoblasts and cardiomyocytes differentiation of iPS cells using non-viral vectors: a new strategy for regenerative medicine
Rui L Reis
Universidade do Minho (UM)

PTDC/SAU-ENB/116112/2009

Machine Learning in Brain Computer Tomography Screening
Victor Alves
Universidade do Minho (UM)

PTDC/SAU-EPI/110066/2009

Quality of Life (QoL) in breast cancer survivors. Influence of the surgical strategy in the Portuguese population
Francisco Luis Maia Mamede Pimentel
Centro de Estudos e Investigação em Saúde da Universidade de Coimbra (CEISUC)

PTDC/SAU-EPI/110166/2009

Environmental epigenetics, a Portuguese survey
Marta Barreto
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-EPI/110922/2009

Contribution to epidemiologic studies on presbiacusis in the portuguese population
Maria Helena Caria
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-EPI/110998/2009

Pharmacoepidemiological Academic Detailing for Portuguese Family Physicians: Bringing Pharmacoepidemiology to Where it has the Greatest Impact in Public Health - The Prescribing Act - and Evaluating that Intervention in a Randomized Study of Physicians.
Pedro Afonso Caetano
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-EPI/111111/2009

Spatio-Temporal Modelling of Portuguese Cancer Mortality Patterns
Bruno de Sousa
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-EPI/111408/2009

Study of the prevalence, risk factors and clinical as well as serological features of food allergies in Portuguese children and adults
Luis Manuel Taborda Barata
Universidade da Beira Interior (UBI)

PTDC/SAU-EPI/111939/2009

Progression and compensatory regulation in undifferentiated connective tissue disease
Constantin Fesel
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-EPI/112153/2009

Determinants of the variation in stroke mortality in Portugal and Mozambique
Nuno Miguel de Sousa Lunet
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-EPI/112174/2009

Insomnia in portuguese adolescents. Epidemiology and repercussions in local health strategies.
Carlos Manuel de Figueiredo Pereira
Instituto Politécnico de Viseu (IPV)

PTDC/SAU-EPI/112179/2009

Large scale parallel simulations of the spread of infectious diseases
Andrea Parisi
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-EPI/112492/2009

Determination of the rate of infection by Human Papillomavirus and its molecular characterization in students of the University of Minho
Henedina da Conceição Araújo Antunes
Universidade do Minho (UM)

PTDC/SAU-EPI/112533/2009

Depression, anxiety, and inflammation as predictive factors in the prognosis of Heart Failure
Graça Maria Pereira Cardoso
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-EPI/112793/2009

Epidemiological and molecular diversity of Cryptococcus species in Portugal.
Joao Pedro Silva Frade
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-EPI/112900/2009

Assessment of the prevalence of intimate partner violence, and its relationship to a diagnosis of HIV,in a sample of female drug users in Portugal
Leonie Rita Prasad
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-EPI/113103/2009

Non Invasive Biomonitoring (NIB) - A tool for Metabolic Evaluation and Early Diagnosis
Maria Margarida Boavida Pontes Gonçalves
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FCTUNL/UNL)

PTDC/SAU-EPI/113178/2009

Antimalarial efficacy of the artemisinin combination therapies for Plasmodium falciparum malaria treatment in Maputo
MARIA DE FÁTIMA CARVALHO NOGUEIRA
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-EPI/113326/2009

Factors affecting dynamics of Plasmodium concomitant infections in a malaria endemic area: analysis through a new modelling approach
Ana Paula Martins dos Reis Arez
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-EPI/113585/2009

Study of the prevalence of cognitive deficits and changes in muscle strength associated with angiotensin converting enzyme I/D polymorphism in the elderly
Maria da Assunção Morais e Cunha Vaz Patto
Universidade da Beira Interior (UBI)

PTDC/SAU-EPI/113652/2009

Prevalence of old age neuropsychiatric disorders: contribution to mental health policy in Portugal
Fernando Miguel Teixeira Xavier
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-EPI/113788/2009

Predictors of HIV risk behaviour, patterns of HIV testing, and prevalence of HIV among men in Portugal
Henrique Pereira
ISPA, CRL (ISPA)

PTDC/SAU-EPI/113958/2009

INTERPLANT- Herbal Products and Conventional drugs - What interactions? a case study In Madeira Island
Paula C Castilho
Universidade da Madeira (UMA)

PTDC/SAU-EPI/114073/2009

Impact of genetic diversity on the pathogenesis of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)
Maria Miragaia
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-EPI/114525/2009

Second primary tumours in prostate cancer survivors: frequency, etiology and survival
Nuno Miguel de Sousa Lunet
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-EPI/114744/2009

Searching for epidemicity genomic markers in high-level gentamicin and glycopeptide resistant nosocomial enterococci: a multicenter study in Portugal.
Rosario Mato Labajos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-EPI/114905/2009

Prospective study to determine cardiovascular risk of the population living in the northern region of Portugal: the Guimarães Pilot Study
Jorge de Almeida Berkeley Cotter
Universidade do Minho (UM)

PTDC/SAU-EPI/114909/2009

Health Literacy in Chronic Disease [HEALITER]
António Barbosa
Faculdade de Medicina da Universidade de Lisboa (FM/ULisboa)

PTDC/SAU-EPI/115046/2009

Randomised controlled study on effectiveness of providing personalised feedback on genetic susceptibility to lung cancer to smokers wanting to quit
Maria de Fátima Calado Varela Reis
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-EPI/115462/2009

Investigation of Clostridium difficile-associated disease in Algarve Hospitals
Maria Leonor Faleiro
Universidade do Algarve (UAlg)

PTDC/SAU-EPI/115538/2009

Genetic epidemiology of stroke: searching for genes contributing to stroke risk, recovery and variable response to tissue plasminogen activator (tPA) therapy in a Portuguese population sample
Astrid Vicente
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-EPI/115749/2009

Molecular epidemiology of HIV infection on mother-to-child transmission
Elizabeth Pádua
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-EPI/115853/2009

Dengue in Madeira archipelago. Risk assessment for the emergence of Aedes aegypti mediated arboviroses and tools for vector control.
Carla Alexandra Gama Carrilho da Costa Sousa
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-EPI/115899/2009

Sexual Dysfunction Observational Study in Portugal (SEXOS): Treatment-seeking behavior of sexual dysfunctions
Alberto Adriano Archer Galvão Teles
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-EPI/116060/2009

DATA MINING/MULTIVARIATE DATA ANALYSIS FOR MODELING METABOLIC SYNDROME AMONG ADOLESCENTS IN OEIRAS
Jaime Raúl Seixas Fonseca
Instituto Superior de Ciências Sociais e Políticas (ISCSP/Ulisboa)

PTDC/SAU-EPI/116227/2009

Dynamics of the pandemic influenza AH1N1 genetic evolution by co-circulation with seasonal influenza viruses, Functional compatibility of the replication complex as determinant of virulence
Helena Rebelo-de-Andrade
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-SAP/109849/2009

Helicobacter pylori genetic variation in virulence factors: An opportunity to identify individuals at increased risk for disease
Ceu Figueiredo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-SAP/109953/2009

Assessment of urban public transport and international air transport as reservoirs of methicillin-resistant staphylococci
Paulo Manuel Rodrigues Martins da Costa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-SAP/110217/2009

Epidemiological surveillance of Staphylococcus aureus in Portuguese-speaking African countries
Marta Aires de Sousa
Cruz Vermelha Portuguesa (CVP)

PTDC/SAU-SAP/110241/2009

Healing Plant Species
Isabel Maria Freire Martins Madaleno
Instituto de Investigação Científica Tropical,I.P. (IICT) (IICT/MNE)

PTDC/SAU-SAP/110302/2009

TOWARDS A BETTER UNDERSTANDING OF AGEING AND OLDER PEOPLE. Development and Ageing in the Região Norte of Portugal: Longitudinal Study - Wave 1
António Manuel Godinho da Fonseca
Universidade Católica Portuguesa (UCP)

PTDC/SAU-SAP/110581/2009

Extended-spectrum beta-lactamase producers at hospital and community: contribution of aging population care, for dissemination
Helena Maria Neto Ferreira de Sousa
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-SAP/110799/2009

Increasing physical activity in older adults: walking by prescription in primary care setting
Claudia Carvalho
ISPA, CRL (ISPA)

PTDC/SAU-SAP/110908/2009

Water Disinfection By-products in Indoor Swimming Pools: Environmental Exposure, Genetic Damage and Reproductive Effects
Ana Sofia Vilhena Fernandes Pereira Cardoso
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-SAP/110911/2009

Pulmonary Tuberculosis in Portugal: space-time assessment of both notified incidence and determinants, trends and future scenarios for a better control.
Carla do Rosário Delgado Nunes de Serpa
Escola Nacional de Saúde Pública (ENSP/UNL)

PTDC/SAU-SAP/111357/2009

Impact of intervention on water and sanitation in the burden of disase of intestinal parasitosis in a rural area of Mozambique
Sónia Chavarria Alves Ferreira Centeno Lima
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/111423/2009

PLACaRD - Phenotypes, prevaLence And Control of Chronic Respiratory Diseases in the Portuguese population
João A Fonseca
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-SAP/111481/2009

Salm_ALERT: Molecular Identification of Resistance Mechanisms in Salmonella through Determinants Recognition
Patrick de Oliveira Freire
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-SAP/111482/2009

Analytical tools to study the effect of cosmic radiation exposure in professional airline pilots.
Pedro Tavares
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-SAP/111908/2009

Maternal-infant health related to environmental factors (IN-health)
Maria Angela Pereira Serafim
Universidade do Algarve (UAlg)

PTDC/SAU-SAP/111921/2009

Occupational Exposure and Environmental Impact of Polycyclic Aromatic Hydrocarbons: Influence of Forest Fires
Maria do Carmo Pereira
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-SAP/111964/2009

PT100 Portuguese Centenarian
Maria Constança Paúl
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-SAP/112302/2009

Aquatic environments as reservoirs of antimicrobial resistance genes and virulence factors: a risk for Public Health
Nuno Mendonça
Universidade de Coimbra (UC)

PTDC/SAU-SAP/112888/2009

Control and treatment of Taenia solium cysticercosis/taeniasis through improved diagnosis and patient monitoring
Michael Parkhouse
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-SAP/112963/2009

Interactions between ageing, work ability and exposure to physical and mental demands among nurses
Teresa Margarida Crato Patrone de Abreu Cotrim
Faculdade de Motricidade Humana (FMH/ULisboa)

PTDC/SAU-SAP/113050/2009

Expert voices on embryonic stem cell research: expectations, regulation and ethics
SUSANA MANUELA RIBEIRO DIAS DA SILVA
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-SAP/113364/2009

DISPHTHAL - Assessment of endocrine disruptors (phthalates) exposure of Portuguese population: prospective social safety and health evaluation and development of a phthalates-specific chemical sensor
Elvira Maria Mendes Sardão Monteiro Gaspar
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-SAP/113523/2009

Ecoepidemiology of Dirofilaria spp: molecular characterization, potential vectors and transmission dynamics
Silvana Maria Duarte Belo
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/113549/2009

Bromate in drinking water: development and application of fast automatic methods
Marcela Alves Segundo
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-SAP/113651/2009

Use of cephalosporins in pigs - assessing the link between usage, resistance and food safety
Maria Constança Matias Ferreira Pomba
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-SAP/113908/2009

Vestigial presence of antibiotics in ready-to-eat foods: may biochemical alterations be induced in their presence?
Cristina Prudêncio
Instituto Politécnico do Porto (IPP)

PTDC/SAU-SAP/114111/2009

Environmental injustice at Porto using tuberculosis as indicator
Ana Maria Rodrigues Monteiro de Sousa
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-SAP/114200/2009

SAFECEPH - Intake of cholesterol and chemical contaminants through cephalopods consumption by Portuguese population: Health risks
Maria leonor Martins Braz de Almeida Nunes
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-SAP/114273/2009

Searching for endogenous and nutritional factors underlying alterations in plasma aminothiol content in apparently healthy Azorean subjects
Maria Leonor Pereira de Almeida Pavão Sequeira de Medeiros
Universidade dos Açores (UAçores)

PTDC/SAU-SAP/114779/2009

Lower limb interjoint coordination of basketball players during an incenting event of ankle sprain
Maria António Ferreira de Castro
Instituto Politécnico de Coimbra (IPC)

PTDC/SAU-SAP/114837/2009

Assessment of contamination in population groups exposed to radiological agents by micro-EDXRF analysis of Pb concentrations in teeth, calibrated by Monte Carlo methods
JORGE MIGUEL DE BRITO ALMEIDA SAMPAIO
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-SAP/114922/2009

Risk factors for consumer from live bivalve molluscs production areas: Quantification, identification and tracking of faecal contamination sources and assessment of Vibrionaceae levels
Sónia Cristina Nunes Salvador Correia Pedro
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-SAP/115028/2009

Portuguese artisanal foods: a source of emergent pathogenic yeasts and a threat to an ageing population?
Teresa Maria Fonseca de Oliveira Gonçalves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-SAP/115116/2009

Diabetes and aging on male reproductive function: functional analysis of Sertoli cells and Sperm
Sandra Catarina Gomes Amaral
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-SAP/115188/2009

Detection of latent tuberculosis infection in a population of Portuguese drug users: a comparison of the tuberculin skin test and the T-Spot.TB test
Leonie Rita Prasad
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-SAP/115196/2009

Portugal's receptivity to mosquito borne arbovirus potencialy circulating in the Mediterranean basin, due to the climatic changes in course. ARBOPORT
António Paulo Gouveia de Almeida
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/115241/2009

SpatialRisk - Establishing a methodology for evaluation of hazard maps for emergency management, mitigation and priorities setting for an infectious vector-borne disease of high risk in Portugal - West Nile virus
Maria da Conceição Machado Sangreman Proença
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-SAP/115266/2009

Q fever - from diagnosis to eco-epidemiological investigation of Coxiella burnetii in the context of human infection
Ana Sofia Santos
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-SAP/115481/2009

Pharmaceutical drugs as contaminants of waters. Regional relevance using an analytical track and trace approach
Alberto da Nova Araujo
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-SAP/115522/2009

E-health on prevention of depression
Anabela Maria Sousa Pereira
Universidade de Aveiro (UA)

PTDC/SAU-SAP/115545/2009

A MODEL FOR MEDICAL ETHICS DELIBERATION (MED)
Ana Sofia Araújo Pinto de Carvalho
Universidade Católica Portuguesa (UCP)

PTDC/SAU-SAP/115575/2009

Alert system prototype for the pollution effects on public health applied to the Lisbon area
AMÍLCAR DE OLIVEIRA SOARES
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-SAP/115578/2009

The role of efflux pumps on the resistance phenotype of Toxocara canis to disinfectant agents and analysis of new herbal compounds as efflux pumps inhibitors.
Ana Júlia Pinto Fonseca Sieuve Afonso
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/115611/2009

Effects of psychosocial determinants of health in workplace: their inter-relationship and behavior over time
Ana Maria Amorim Sampaio da Silva
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-SAP/115748/2009

Violence across life ages and its effects on health
JOSÉ HENRIQUE DIAS PINTO DE BARROS
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-SAP/116024/2009

Diabetes in children and elderly: pilot study to assess the health gains achieved by the use of innovative diabetes management device
Pedro Parreira
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-SAP/116203/2009

Fever screening of Portuguese children and adults with a thermal camera
Luis Filipe Fernandes Silva Marcelino
Instituto Politécnico de Leiria (IPLeiria)

PTDC/SAU-TOX/109792/2009

Molecular and cellular interactions of cocaine and opioids- implications in speedball neurotoxicity
MARIA TERESA MARTINS DA CUNHA OLIVEIRA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/109820/2009

Investigation of cellular pathways for bile acid injury during icteric and non-icteric cholestasis in human hepatocytes.
Rui Fernando Marques da Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/109857/2009

Cardiac and Skeletal Muscle Mitochondrial Dysfunction During Hyperglycaemia - Role of the Permeability Transition, Apoptosis and Autophagy and Prevention of Damage by Carvedilol
Maria Sancha de Jesus Vieira dos Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/109876/2009

In vivo study of sirolimus analogous effects in invasive urothelial cancer chemical induced and their correlation with effects in human invasive cancer cell lines
Paula Alexandra Martins de Oliveira
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/SAU-TOX/109993/2009

Compounds that compete with efflux of anti-cancer drugs by ABC transporters: a pathway for the reduction or reversal of resistance of multi-drug resistant cancer cells
Leonard Amaral
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-TOX/110180/2009

Os efeitos tóxicos de nanopartículas de prata e ouro: um estudo in vivo para avaliação de toxicidade mitocondrial.
Carlos Palmeira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/110391/2009

Beta secretase inhibitor screening for potencial treatment of Alzheimer´s Disease
Pedro Miguel Dias Castanheira
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/SAU-TOX/110398/2009

Synthesis and Investigation of Cytotoxic Activity of 1,2-disubsituted Ferrocene Compounds
Zeljko Petrovski
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-TOX/110424/2009

Alpha2c adrenoceptor control of L-DOPA uptake and dopamine synthesis in the central nervous system and its application to the therapeutics of Parkinson´s disease
Jose Eduardo Ferreira Moura
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-TOX/110457/2009

Development of 3D culture models for human ucmMSC-derived hepatocytes for predictive toxicology and cell therapy
Joana Paiva Gomes Miranda
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/110570/2009

Comprehensive study on the effect of the combined use of epigenetic-modifying drugs in prostate cancer
Carmen Jerónimo
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-TOX/110919/2009

Surfactants in the Prophylaxis of Sexually Transmitted Infections and in Oral Hygiene
Otília Vieira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/110965/2009

Direccionamento de celulas T activadas para iniciar respostas imunitária protectoras apropriadas ao modo de vida dos patogénios.
Elisabetta Padovan
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-TOX/111269/2009

Targeting lactate transport in cervical cancer: in vitro and in vivo studies
Maria de Fátima Monginho Baltazar
Universidade do Minho (UM)

PTDC/SAU-TOX/111403/2009

Papel dos receptores de adenosina em doenças relacionadas com o stress oxidativo: influência dos níveis de EROS e dos efeitos mediados pelo NO no cancro e na hipertensão
Carmen Diniz Pereira
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/111525/2009

Bioavailability of amphiphilic ligands. Equilibrium and Kinetics of their interaction with lipid assemblies using Isothermal Titration Calorimetry
Maria João Pedrosa Ferreira Moreno Silvestre
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-TOX/111663/2009

Hepatic toxicity in HIV-infected individuals exposed to nevirapine
Maria Emilia Carreira Saraiva Monteiro
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-TOX/111788/2009

Early or late cyclosporin A to sirolimus conversion in kidney transplantation? - Cardiorenal biomolecular basis and best antihypertensive/renoprotective therapy
Flávio Nelson Fernandes Reis
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-TOX/111852/2009

From drug-induced mitochondrial dysfunction to epigenetic reprogramming: modulation of acetyl-CoA bioavailability
Margarida Maria Fernandes Baptista e Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/111853/2009

The effect of membrane cholesterol on the mechanism of aluminium neurotoxic action on (Na+/K+)ATPase activity.
Virgília Sofia Almeida de Azevedo e Silva
Universidade de Aveiro (UA)

PTDC/SAU-TOX/111905/2009

Brain metabolism, inflammation and degeneration in in vivo type 2 diabetes-associated stroke: Role of insulin and exendin-4
Ana Isabel Marques Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/112264/2009

Chronic Intermittent Eucapnic Hypoxia: systemic effects and evaluation of anti-hypertensive drugs efficacy
Maria Emilia Carreira Saraiva Monteiro
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-TOX/112472/2009

Prospective study of individualization of isoniazid therapy by NAT2 genotyping: impact on hepatotoxicity
Henriqueta Alexandra Mendes Brêda Lobo Coimbra Silva
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-TOX/112510/2009

Intrarenal renin-angiotensin system activation in Heart Failure: angiotensinogen as a new potential integrative biomarker and its clinical consequences in cardiorenal syndrome
António Albino-Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-TOX/112641/2009

Biological and potential therapeutic role of AMPK in the pathogenesis of renal injury and inflammation
António Pedro Barros Gomes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-TOX/112668/2009

New anti-inflammatory agents from tropical medicinal plants
Olga Maria Duarte Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/112729/2009

Role of the receptor for advanced glycation end products (RAGE) in methamphetamine-induced neurotoxicity
Frederico Guilherme de Sousa da Costa Pereira
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-TOX/112819/2009

Exploiting the apoptotic potential of lycopene: a trip starting with tomato-based products and ending on a topical preparation for preventing or treating the effects of UV damages in human skin
Sandra Simões
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/112905/2009

Involvement of cyclic nucleotides compartmentalization in vasodilatation
Ignacio Verde
Universidade da Beira Interior (UBI)

PTDC/SAU-TOX/113013/2009

New therapeutic strategies for prevention of multiple organ dysfunction associated to systemic inflammation of various aetiologies
Bruno Miguel Nogueira Sepodes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/113244/2009

Interactions between herbal weight loss extracts and antiepileptic drugs: the risk of further seizures
Gilberto Lourenço Alves
Universidade da Beira Interior (UBI)

PTDC/SAU-TOX/113255/2009

Therapeutic Potential of Novel Bile Acid Conjugates in Experimental Parkinson´s Disease
Joana São José Dias Amaral
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/113569/2009

ASSESSMENT OF FETAL DRUG EXPOSURE THROUGH MECONIUM ANALYSIS.
Eugenia Gallardo
Universidade da Beira Interior (UBI)

PTDC/SAU-TOX/113588/2009

Antimalarial pharmacogenomics
Jose Pedro Blanco Panadés Gil
Universidade do Algarve (UAlg)

PTDC/SAU-TOX/113955/2009

Inhibition of P-glycoprotein by standardized herbal extracts: a herbal screening research program targeting multidrug resistance
Gilberto Lourenço Alves
Universidade da Beira Interior (UBI)

PTDC/SAU-TOX/113956/2009

Targeting autophagy in Acute Myeloid Leukaemia: Impact on therapeutic approaches
Paula Cristina da Costa Alves Monteiro Ludovico
Universidade do Minho (UM)

PTDC/SAU-TOX/113975/2009

Cardiovascular drugs with a narrow therapeutic range and herbal weight loss products: the risk of harmful herb-drug interactions
Amílcar Celta Falcão Ramos Ferreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/113984/2009

Pharmacometric assessment of the potential for the nasal administration of fluoroquinolones in the treatment of chronic rhinosinusitis
Amílcar Celta Falcão Ramos Ferreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/114097/2009

Synthesis, characterization, and toxicity evaluation of gold nanoparticles
Maria de Lourdes Bastos
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/114323/2009

Acrylamide and breast cancer: characterization of the transformation potential of acrylamide and of its reactive metabolite glycidamide in 3D human non malignant mammary cells
Nuno Filipe da Rocha Guerreiro de Oliveira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/114415/2009

Liposomal delivery of nystatin with simultaneous improvement of antifungal activity and reduction of toxicity on human cells
Liana C Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/114424/2009

Cellular therapy for liver-specific immune suppression
Luis Ricardo Silva Graca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-TOX/114488/2009

Endothelin-1 antagonism in experimental pulmonary hypertension: unraveling the mechanisms underlying myocardial effects and potential therapeutic implications
Paulo Manuel Castro Chaves
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-TOX/114503/2009

Screening, characterization and mechanisms of natural pinane derivatives as possible anti-osteoarthiritic leads for drugs
Carlos Manuel Freire Cavaleiro
Universidade de Coimbra (UC)

PTDC/SAU-TOX/114671/2009

Direct action of diuretic drugs and aldosterone on kidney potassium channels
Ana Isabel Dias Bicho dos Santos
Centro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR)

PTDC/SAU-TOX/114705/2009

Central and peripheral changes in Huntington's disease - a focus on metabolic dysfunction and nitric oxide-mediated stress upon IGF-1 and insulin treatment
Ana Cristina Carvalho Rego
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/114848/2009

Redox stress and S-glutathionylation in the PERK - Nrf2 pathway.
Maria João Carlos da Silva Gama
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/115155/2009

New therapeutical approach for melanoma: Cytotoxicity mechanisms of combined therapies of vitamin D and A derivatives with 4-hydroxytamoxifen and endoxifen
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/115165/2009

PURINERGIC MODULATION AND REMODELLING OF HUMAN CAVERNOSAL VESSELS: RELEVANCE IN THE PATHOPHYSIOLOGY OF DIABETES-RELATED ERECTILE DYSFUNCTION
José Maria Ferreira La Fuente de Carvalho La Fuente de Carvalho
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-TOX/115197/2009

Cardiovascular and metabolic effects of AT-1-blockers independent from the competitive antagonism of angiotensin II
Helder Jose Marques Pinheiro
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/115367/2009

PURINERGIC SIGNALING IN A NOVEL TRIPARTITE MYENTERIC SYNAPSE: FUNCTIONAL RELEVANCE
Margarida Duarte Cerqueira Martins de Araújo
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-TOX/115677/2009

Evaluation of diepoxybutane toxicokinetics and toxicodynamics in human leukocytes, for a better understanding of the Fanconi anemia etiology
Maria Beatriz Beça Gonçalves Porto e Vasconcelos
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-TOX/115767/2009

Functional and molecular maturation of the sympathetic system
Daniel Filipe de Lima Moura
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-TOX/115916/2009

Development of a nomogram based on molecular and clinical markers and genomic toxicity for a better prediction of the radiotherapy response in breast cancer patients
RUI Manuel de MEDEIROS Melo Silva MEDEIROS
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-TOX/115947/2009

Effect of life-span voluntary exercise against anti-cancer therapy-induced cardiac dysfunction - Relevance of mitochondrial permeability transition and apoptosis
António Alexandre Moreira Ribeiro de Ascensão
Faculdade de Desporto da Universidade do Porto (FADE/UP)

PTDC/SAU-TOX/116001/2009

Do caffeine and adenosine A2A receptor antagonists prevent neurotoxicity and memory dysfunction caused by prion protein?
PAULA MARIA GARCIA AGOSTINHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/116152/2009

Adenosine as the first putative mechanism for differential regulation of circulating and renal renin-angiotensin systems: relevance for the treatment of renal injury associated with hypertension
Manuela Morato
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FAR/109779/2009

NanoLBG: Development of locust bean gum-based nanocarriers for oral delivery of therapeutic macromolecules
Ana Margarida Moutinho Grenha
Universidade do Algarve (UAlg)

PTDC/SAU-FAR/110003/2009

Biocompounds from a terrestrial organism: source of a new antbiotic?
Luisa Maria Sobreira Vieira Peixe
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/110188/2009

Nanotechnology strategies and new bioactive molecules for treatment of methicilin resistant staphylococcus aureus infections
Maria Manuela de Jesus Guilherme Gaspar
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/110665/2009

Restauration of e-cadherin by a paclitaxel-nanoparticulate system as a new tool to eradicate tumor metastatic phenotype
Mafalda de Castro Ascensão Marques Videira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/110871/2009

Mechanistic study of the adjuvant effect of nanoparticulate systems used as an immunotherapeutic strategy against melanoma
Helena Isabel Fialho Florindo Roque Ferreira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/110873/2009

Non-invasive viral gene therapy for the central nervous system: Silencing Machado-Joseph disease by the systemic or intracisternal routes
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/110886/2009

Targeting caspases for the inhibition of apoptosis: design, synthesis and biological evaluation of vinyl sulfones as a new family of caspase inhibitors.
Maria Manuel Duque Vieira Marques dos Santos
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/111090/2009

Lipid peroxidation on endothelial membrane: antioxidant role of statins in a biomimetic model
Luis Miguel Andrade de Magalhães
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/111137/2009

New strategies for the metastatic melanoma therapy
Maria de Jesus Almeida Rainha Perry da Câmara Saldanha Rocha
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/111913/2009

Potential nanoparticle-based delivery systems for release of ursodeoxycholic acid in the brain: overcoming the blood-brain barrier
Ana Alexandra Figueiredo Matias
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-FAR/112210/2009

Influence of fluid therapy on Local and Systemic Inflammation, and on Drug Therapy. Role of New Drug Delivery Systems and Nanomedicine
Maria Luísa Teixeira de Azevedo Rodrigues Corvo
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/112435/2009

Flavonoids with potential anti-inflammatory activity: in vitro and in vivo evaluation of their effects in pro-inflammatory signalling systems
Eduarda das Graças Rodrigues Fernandes
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/112514/2009

Nanocarrier mediated delivery of topical photosensitizers to thick non melanoma skin cancers
Maria Barbara dos Anjos Figueira Martins
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/112524/2009

Targeted intracellular delivery of synergistic drug combinations: a novel approach to deal with drug resistance in human breast cancer.
João Nuno Sereno de Almeida Moreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/112767/2009

CYD-DDS (cyclodextrin-based drug delivery systems) for inflammation
Helena Maria Cabral Marques
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/112836/2009

EyeNanoDiab - Prevention and treatment of diabetic retinopathy by natural antioxidant containing in chitosan-based nanomedicines
Bruno Sarmento
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FAR/112843/2009

Development of new therapeutic strategies for breast cancer: Glutamate antagonists and aromatase inhibitor derivative in combination or in sequence with active tamoxifen metabolites
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/112849/2009

HypeNanoBrain - Exploiting Hypericum perforatum antioxidant and neuroprotective properties through targeted brain extracts and compounds delivery via nanoparticles
Bruno Sarmento
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-FAR/113019/2009

Molecular and functional characterization of pro-apoptotic compounds isolated from Penicillium chrysogenum strains
Francisco Javier Enguita
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-FAR/113215/2009

(E)-2-STYRYLCHROMONES: POTENTIAL ANTIVIRAL AGENTS WITH ANTI-NOROVIRUS ACTIVITY
Maria de São José Garcia Alexandre
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FAR/113355/2009

Hiperbilirubinemia in age-related process
Elsa Maria Ribeiro Bronze da Rocha
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FAR/113405/2009

Novel therapeutic strategy for Parkinson's disease combining an anti-inflammatory, cyclodextrin and poloxamer
Ana Figueiras
Universidade da Beira Interior (UBI)

PTDC/SAU-FAR/113614/2009

Water soluble glycodendritic-phthalocyanines for cancer imaging and therapy
Rosa Cristina S Fernandes
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-FAR/113703/2009

Study of the antituberculous activity of antibacterial agents with a novel mechanism of action
Anabela Medo Miranda
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-FAR/113886/2009

Solid dispersions of benzodiazepine for transmucosal delivery
Carla Martins Lopes
Fundação Ensino e Cultura Fernando Pessoa (FECFP)

PTDC/SAU-FAR/113890/2009

New approaches for leishmaniasis treatment: applications to HIV/Leishmania coinfection
Maria do Céu Rodrigues de Sousa
Universidade de Coimbra (UC)

PTDC/SAU-FAR/114085/2009

Discriminating cytochrome P450 enzymes. Evaluation of specific molecular features of CYP19.
Maria Luisa Campeão Fernandes Vaz Sá Melo
Universidade de Coimbra (UC)

PTDC/SAU-FAR/114164/2009

Nanostructured biomimetic interfaces for enzyme studies applications
Jose Luis Fontes da Costa Lima
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/114274/2009

PlatinLung - Targeting anticancer cisplatin to non-small lung cancer cells through nano-sized polymer conjugates
Vitor Seabra
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-FAR/114276/2009

Influence of bioactive dietary compounds on membrane function: Role in protection against oxidative damage and disease
Maria de La Salette de Freitas Fernandes Hipólito Reis
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/114864/2009

TARGETING HEMOZOIN CRYSTAL STRUCTURE: A RATIONAL APPROACH TO THE DESIGN OF NOVEL ANTIMALARIALS
Maria Alexandra da Silva Paulo
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/114913/2009

Prediction of Intestinal Transporter-Effects on the Absorption of Metabolized Drugs
José Augusto Guimarães Morais
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/114967/2009

Exploring mycobacteriophage endolysins as a tool to target the Mycobacteria cell envelope
Madalena Maria Vilela Pimentel
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-FAR/115290/2009

Development and pre-clinical evaluation of a new HIV-1 vaccine concept
Nuno Eduardo Moura dos Santos da Costa Taveira
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-FAR/115389/2009

Interpretation of the profiles Bs resulting from complexation of several drugs with β-cyclodextrin
Paulo José Pinto Salústio
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/115435/2009

Regulation of JNK signal transduction pathways by Hsp70 in experimental models of Parkinson's disease
Margarida Casal Ribeiro Castro Caldas Braga
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/115822/2009

ConfocalSkin - Going through confocal skin imaging to assess effectiveness of dermal drug delivery nanocarriers
Domingos de Carvalho Ferreira
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FAR/115846/2009

Albumin binding-domain fusions to improve protein pharmacokinetics
Joao Goncalves
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-FAR/115963/2009

EVALUATION OF THE THERAPEUTIC POTENTIAL OF TAMOXIFEN IN THE TREATMENT OF GLIOBLASTOMA
Maria Celeste Fernandes Lopes
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/116148/2009

Understanding influence of M cells on intestinal uptake of oral hipoglycemic insulin-loaded nanoparticles
FRANCISCO JOSÉ DE BAPTISTA VEIGA
Universidade de Coimbra (UC)

PTDC/SAU-ONC/109806/2009

DEVELOPMENT OF A FOLLOW-UP AND RADIOBIOLOGICAL RESEARCH PROGRAM
Brígida Costa Ferreira
Universidade de Aveiro (UA)

PTDC/SAU-ONC/109816/2009

Identification of novel cancer biomarkers based on O-glycosylation modifications - Glycoproteomics
Hugo Alexandre Carvalho Pinheiro Osório
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/110168/2009

CDX2-induced alterations of the gastric glycoproteome.
Raquel Maria da Silva Graça Almeida
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/110295/2009

P-cadherin overexpression: an alternative mechanism for E-cadherin loss-of-function in invasive human carcinomas
Joana Cancela de Amorim Falcão Paredes
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/110374/2009

From neural stem/progenitor cells to glioma: dissecting the tumorigenic properties, cell migration, angiogenesis and potential adjuvant chemotherapy
Ana Sofia Iria Azeredo Falcão de Jesus
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ONC/110482/2009

Understand how the actin cytoskeleton restricts signalling by the Src-non-receptor tyrosine kinase proto-oncogene.
Florence Janody
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ONC/110625/2009

Artemisinin derivatives and nitro-fatty acids in prevention of colorectal cancer
Isa da Conceição Lopes Cavaco
Universidade do Algarve (UAlg)

PTDC/SAU-ONC/110721/2009

ETS fusion genes and their targets in prostate cancer and Ewing sarcoma
Manuel António Rodrigues Teixeira
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ONC/110751/2009

Modulation of H-RAS alternative splicing and oncogenic activity; role of the 81T/C polymorphism
Patricia Manuel Costa e Castro
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/110770/2009

Targeting the Warburg effect for cancer therapy
Valdemar de Jesus Conde Máximo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/110786/2009

Identification of a susceptibility locus for gastric carcinoma in the IL1 gene cluster region
José Carlos Lemos Machado
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/111104/2009

Uncovering novel oncogenic signaling properties of BRAF in human cancers
Ana Paula Soares Dias Ferreira
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/111171/2009

The role of PP1/Tctex1d4 holoenzyme in TGFbeta mediated prostate cancer
Margarida Fardilha
Universidade de Aveiro (UA)

PTDC/SAU-ONC/111437/2009

Using zebrafish to understand the role of H2O2 in the establishment of the tumor vascular niche
Carla Sofia Fernandes do Amaral Real Afonso
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ONC/111467/2009

Cancro e microambiente: parceria fatal
Maria Carmen Alpoim
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ONC/111496/2009

Implications of Claspin mutations in the maintenance of cell homoeostasis, oncogenesis and response to chemotherapy
Teresa Maria Caldeira Martins
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ONC/111847/2009

In vivo imaging of stem-like cells in osteosarcoma by high-resolution Positron Emission Tomography
Célia Maria Freitas Gomes
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/111963/2009

Understanding the pathophysiological role of the sialyltransferases and sialylated TF antigens in bladder cancer
Paula Alexandra Quintela Videira
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/112218/2009

Bronchial-Pulmonary Carcinoma in advanced stage: immunohistochemical, molecular and metabolic study for clinical translation
Lina Maria Rodrigues Carvalho
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/112414/2009

MRS, MRI and PET in oncology: new approaches to understand cancer metabolism
Maria Filomena Rabaça Roque Botelho
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/112570/2009

SOX2 and CDX2 negative cross-regulation in the establishement of intestinal metaplasia of the stomach.
Raquel Maria da Silva Graça Almeida
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/112650/2009

Cross-talk between covalent modifications of histone N-terminal tails and DNA methylation for gene expression regulation in prostate carcinogenesis
Carmen Jerónimo
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ONC/112738/2009

Searching for novel genes involved in endometrial oncogenesis
Carolino Jose Nunes Monteiro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ONC/112830/2009

Deciphring the role of regucalcin in breast cancer: cause or consequence?
Sílvia Cristina da Cruz Marques Socorro
Universidade da Beira Interior (UBI)

PTDC/SAU-ONC/112999/2009

TCR/CD3-associated antigens in normal T cell development and leukemogenesis, and as potential therapeutic targets
Mafalda Maria dos Santos Pinto
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ONC/113053/2009

Bioactive sphingolipids and apoptosis unbalance in chronic B-cell lymphoproliferative disorders: Looking for disease biomarkers, for a better understanding of disease biology.
Bárbara Macedo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ONC/113202/2009

Identification of novel regulators of CK2 with impact on PTEN function in leukemia
João Pedro Taborda Barata
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ONC/113234/2009

Activity of Nrf2 in yeast: putative system model for tumour oxidative tolerance
Lisete Celestina Perpétua Fernandes
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ONC/113281/2009

Regulation of EMT in Lung Cancer
Lina Maria Rodrigues Carvalho
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/113341/2009

Identification of new molecular targets that regulate VEGF production in tumor cells.
CRISTINA MARIA TAVARES LINO CASALOU
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/113625/2009

MicroRNAs in the apoptosis pathway and their role in breast cancer susceptibility
Jorge Francisco Dias Rodrigues Gaspar
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/113872/2009

Evaluation of molecular defects in myelodysplastic syndromes and acute myeloblastic leukaemia - prognostic and therapeutic implications
Ana Bela Sarmento Ribeiro
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/113875/2009

Cellular and Molecular alterations in Multiple Myeloma - Clinical and therapeutic implications
Ana Bela Sarmento Ribeiro
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/113897/2009

ANALyAIR - Air analytics - development of a new clinical sensitive method
Elvira Maria Mendes Sardão Monteiro Gaspar
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-ONC/114080/2009

Does Cholesterol promote tumor angiogenesis and metastasis formation?
Sérgio Dias
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ONC/114185/2009

Analysis of miRNAs expression signature in glioblastoma
Durval C Costa
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ONC/114388/2009

NF-KAPPAB TRANSCRIPTION FACTOR ACTIVATION IN ACUTE T-CELL LEUKEMIA
Nuno Alexandre Pinto Rodrigues dos Santos
Universidade do Algarve (UAlg)

PTDC/SAU-ONC/114557/2009

Mitotic Kinetochore In Vivo Molecular Dissection - Implications for Aneuploidy and Cancer
ÁLVARO AUGUSTO MARQUES TAVARES
Universidade do Algarve (UAlg)

PTDC/SAU-ONC/114762/2009

Chronic Myeloid Leukemia: dynamic variation of expression and mutational profiles during tumour progression
José Rueff
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/114821/2009

Predicting and investigating microRNA-protein target pairs associated with hepatocellular carcinoma.
Deborah Penque
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ONC/114911/2009

Mechanisms and functional consequences of Rac1/PAK1-regulated BCL-6 dependent transcriptional repression in colorectal and breast cancer
Paulo Henrique Carrasquinho de Matos
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ONC/115101/2009

How mammalian cells handle topoisomerase-mediated DNA damage - role of chromatin
João António Augusto Ferreira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ONC/115273/2009

New therapeutic approaches to Hepatocellular carcinoma. Phtodynamic Therapy applied to hepatocellular carcinoma
José Guilherme Lopes Rodrigues Tralhão
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/115352/2009

The role of genetic variants of thyroid-specific transcription factors in the susceptibility to familial forms of thyroid cancer
Branca Maria Prudêncio Limón Cavaco
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/115612/2009

MUC1 protein - a new approach to target pancreatic cancer stem cells
Luis Filipe Santos Silva
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/115655/2009

Oral cavity cancer - Tumoral microenvironment study and new prognostic and therapeutic targets
Marília de Assunção Rodrigues Ferreira Dourado
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/115717/2009

Endometrial cancer: tumor cell characterization, serum proteomic profile and implications in metastatic spread in vivo.
Carlos Manuel Domingues Freire de Oliveira
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ONC/115924/2009

Canonical or IRES-mediated translation: Identification of new proteins involved in colorectal cancer
ALEXANDRE RUI DE SAMPAIO TEIXEIRA
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ONC/116021/2009

Biosensors for early cancer disease diagnosis
ALEXANDRE RUI DE SAMPAIO TEIXEIRA
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ONC/116164/2009

Characterization of the Jagged1 ligand endothelial role in the regulation of tumoral neo-angiogenesis
Alexandre José Neto Trindade
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-BID/109917/2009

Developmental control of cell growth and survival by Viriato, a novel nucleolar regulator.
Paulo Jorge Sousa Nunes Pereira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BID/110640/2009

Analysis of the functional specificity of Hox genes in their control of skeletal formation
Moises Mallo
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BID/111035/2009

Unravelling the Transcriptional Program Controlled by Prrxl1 Homeobox Gene in Developing Nociceptors and Target Relay Sensory Neurons
Filipe Almeida Monteiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-BID/111380/2009

Dynamic analysis of Tight Junctions in zebrafish development.
Ana Cristina Ribeiro Borges
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BID/111796/2009

Characterization of mesenchymal to epithelial transition in Drosophila melanogaster
Rui Gonçalo Viegas Russo da Conceição Martinho
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BID/111925/2009

Developmental analysis and tissue specificity of checkpoint genes in Drosophila melanogaster
Sara Luisa Morais da Silva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BID/112080/2009

A New Regulatory Mechanism involving p53 in JMJD3-mediated Neurogenesis
SUSANA ZEFERINO SOLÁ DA CRUZ
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BID/112139/2009

Cilia function in early left-right establishment in vertebrates
Susana Santos Lopes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BID/112191/2009

The Role of ERG Potassium Channel during Vertebrate Limb Induction and Outgrowth
Joaquin Maria Rodriguez-Leon
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BID/112257/2009

Maternal heart rate variability analysis combined with biochemical and psychological factors in the early prediction of spontaneous abortion risk
Maria Irene de Oliveira Monteiro Jesus Rebelo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BID/112911/2009

Understanding the biology of neural development: molecular crosstalk between p63 and tauroursodeoxycholic acid
Filipa Nunes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-BID/113165/2009

Study of the role of the new centrosomal protein TBCCD1 in development
Maria Helena Antunes Soares
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-BID/113528/2009

ISOLATION AND CHARACTERIZATION OF CHROMAFFIN PROGENITOR CELLS FROM NORMAL ADULT HUMAN ADRENAL MEDULLA
CLÁUDIA MARGARIDA GONÇALVES CAVADAS
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-BID/113830/2009

Characterization and functional analysis of the multiple transcripts encoded by the vertebrate embryo molecular clock gene hairy1
Raquel Gláucia Varzielas Pego de Andrade
Universidade do Minho (UM)

PTDC/SAU-BID/113944/2009

Innate Immunity: Identification of Drosophila Rel/NF-kappaB transcriptional targets in vivo
Nina Matova
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BID/113982/2009

Role of HGF/Met signalling pathway in vessel-airway cross-talk during pulmonary morphogenesis
SANDRA MARIA ARAÚJO DA COSTA
Universidade do Minho (UM)

PTDC/SAU-BID/114027/2009

Role and regulation of the actin cytoskeleton in growth control through the Hippo tumor suppressor pathway.
Florence Janody
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BID/114131/2009

V2 interneuron lineage: a model for cell fate determination in the developing nervous system
Domingos Manuel Pinto Henrique
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BID/114254/2009

Zebrafish as an in vivo biomedical model to study vertebral bone fusion - ZeFusion
Leonor Cancela
Centro de Ciências do Mar (CCMar)

PTDC/SAU-BID/114560/2009

Analysis of the functional, cellular and molecular effects of glucagon-like peptide 2 on an animal model of short bowel syndrome
Francisco José Franqueira de Castro e Sousa
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-BID/114902/2009

Role of the novel gene Ccbe in heart induction and organogenesis
José António Henriques de Conde Belo
Universidade do Algarve (UAlg)

PTDC/SAU-BID/115264/2009

Notch signalling in the specification and differentiation of thymic epithelial cells during embryogenesis.
Hélia Cristina de Oliveira Neves
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BID/115405/2009

Comunity Resource for Higher Resolution Imaging of Cell and Developmental Biology Structures
Monica Bettencourt Carvalho Dias
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ORG/109928/2009

Metabolic Profiling of Human Bronchial Epithelial Cells at Different Stages of Exposure to Carcinogenic Cr(VI).
Ana Margarida Malaquias Pires Urbano
Faculdade de Ciências e Tecnologia da Universidade de Coimbra (FCT/UC)

PTDC/SAU-ORG/109943/2009

Computer alerts for intrapartum fetal monitoring signals
Diogo de Matos Graca Ayres de Campos
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-ORG/110015/2009

Resolution of the critical source of GNE activity in vivo in relation to Heterologous Inclusion Body Myopathy.
Jennifer Rowland
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ORG/110179/2009

The future of fatty livers in surgery and transplantation: is preconditioning and mitochondrial tolerance a useful strategy to overcome ischemia/reperfusion injury?
Carlos Palmeira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/110386/2009

Inflammation, iron and lipid homeostasis: a new perspective to study the role of immune cells in atherogenesis
LUCIANA MARIA GONÇALVES DA COSTA
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-ORG/110619/2009

Wnt signaling and heart failure
Sonia Alexandra Vieira e Pinho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/110745/2009

Adenosine in glomerular mesangial cells: moving towards a more complete blockade of the renin-angiotensin system.
Manuela Morato
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ORG/110856/2009

Analysis of a new pathway to import iron into the retina: role of ferritin as iron carrier and implications in radical detoxification.
Jesús Ruberte París
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-ORG/111003/2009

Biomarkers of endothelial dysfunction after coronary stent implantation
Maria Teresa Ferreira Marques Pinheiro
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-ORG/111072/2009

MSC transplantation: an add-on option for remyelination and axonal regeneration?
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/111129/2009

Unraveling the function of Tctex1d4 in sperm physiology and male fertility
Margarida Fardilha
Universidade de Aveiro (UA)

PTDC/SAU-ORG/111244/2009

Role of sirtuins in the progression of endothelium dysfunction in human corpus cavernosum during aging.
Delminda Gamelas Neves Lopes de Magalhaes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/111378/2009

Vertebral Manipoulation effect on electrocardigraphic parameters
Maria António Ferreira de Castro
Instituto Politécnico de Coimbra (IPC)

PTDC/SAU-ORG/111379/2009

Physiological and Clinical Importance of the Parasympathetic Nervous System in Glucose Homeostasis
Andrea Natali
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ORG/111417/2009

Is insulin a stimulus for carotid body activation? A new mechanism for insulin resistance and hypertension.
SÍLVIA MARGARIDA VILARES SANTOS CONDE
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ORG/111622/2009

Crosstalk between retinal ganglion cells and microglia: neuroprotection by adenosine receptors in glaucoma
Ana Raquel Sarabando Santiago
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ORG/111736/2009

Function of Arl13b in membrane traffic and cilium biology
Duarte Barral
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ORG/111874/2009

Obesity and prostate cancer: adipose tissue molecular signature and pathways involved in the interaction with tumor
RUI Manuel de MEDEIROS Melo Silva MEDEIROS
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ORG/111930/2009

Targeting microRNA-34, a Potential Link between Apoptosis and Nonalcoholic Fatty Liver Disease Pathogenesis
Rui E Castro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/111933/2009

Pathophysiological impact of obesity and pressure-overload in diastolic heart failure progression.
Joaquim Adelino Correia Ferreira Leite Moreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/112087/2009

Cardiovascular risk stratification in the percutaneous cardiovascular intervention procedures. ACROSSP (Angioplasty and Coronary Revascularization on Santa Cruz Hospital) registry
Rui Manuel Campilho Pereira de Menezes
Instituto Superior de Ciências do Trabalho e da Empresa (ISCTE)

PTDC/SAU-ORG/112112/2009

Obesity in peritoneal dialysis uremic patients: relationship with peritoneal membrane status and peritoneal dialysis prescription
Anabela Rodrigues
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ORG/112310/2009

Function of micro-RNA in the control of cardiac progenitor cells proliferation and differentiation
Luis Afonso Bras Simoes Rosario
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ORG/112312/2009

Programmed Necrosis in Liver Disease
Cecília Maria Pereira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/112352/2009

Dissecting the molecular mechanisms of EPC response to myocardial ischemia in diabetes: from bench to bedside
Rosa Cristina S Fernandes
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ORG/112456/2009

Study of the actions of testosterone and dihydrotestosterone at the vascular level
Ignacio Verde
Universidade da Beira Interior (UBI)

PTDC/SAU-ORG/112502/2009

Mechanisms of natriuretic peptide system dysfunction in nephrotic syndrome: relationship with reduced renal dopaminergic system activity and vitamin D3 deficiency.
Manuel Pestana
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/112530/2009

LIM homeodomain Islet-1 transcriptor factor as a marker of cellular pluripotency
Luis Afonso Bras Simoes Rosario
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ORG/112649/2009

LARGE GRANULAR LYMPHOCYTE LEUKEMIA: TOWARDS A BETTER UNDERSTANDING OF THE DISEASE BIOLOGY AND THE GENESIS OF THE ASSOCIATED CYTOPENIAS
MARGARIDA LIMA
Centro Hospitalar Universitário do Porto (CHP/MS)

PTDC/SAU-ORG/112678/2009

Unravelling the role of microglia and inflammation in bilirubin-induced neurologic dysfunction (BIND): from in vitro and ex vivo studies to BIND animal models
Dora Brites
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/112683/2009

S-Adenosyl homocysteine, non-histone protein hypomethylation, and vascular disease: another brick in the wall?
Maria Rita M A Azevedo e Castro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/112745/2009

Classical Galactosemia: can we go further?
Isabel Maria Antolin Martins-de-Carvalho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/112757/2009

Study of the relationship between H-Ras and the cGMP pathway in the regulation of rat cardiomyocyte function
Ignacio Verde
Universidade da Beira Interior (UBI)

PTDC/SAU-ORG/112813/2009

SYNAPTIC DYSFUNCTION IN A MOUSE MODEL OF MACHADO JOSEPH DISEASE
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/112822/2009

Regucalcin expression and functional role in human prostate
Cláudio Jorge Maia Baptista
Universidade da Beira Interior (UBI)

PTDC/SAU-ORG/112832/2009

A new approach for the identification of osteoarthritis terapeutic targets:The application of 2D-DIGE proteomics
Dina Costa Simes
Centro de Ciências do Mar (CCMar)

PTDC/SAU-ORG/112946/2009

Volatile biomarkers in the exhaled air: Application to diagnosis, prognosis and therapeutic efficacy of renal cell carcinoma
Paula Guedes de Pinho
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ORG/113152/2009

Hormone-dependent breast and prostate cancers: new molecules and potential targets
Natércia Aurora Almeida Teixeira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/113175/2009

Mechanisms of chondrocyte resistance to hyperglycemia: modulation of ATP-inhibited K+ channels and causes of failure in osteoarthritis
Alexandrina Maria Ferreira dos Santos Pinto Mendes
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/113186/2009

Cumulus oophorus cell and follicular fluid biomarkers as predictors of reproductive success
Henrique Almeida
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/113201/2009

Cross-talk between adipose tissue and adrenal medulla: a role in the metabolic syndrome?
Laura Virgínia Pereira Teixeira Ribeiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/113259/2009

Sex hormone induction of transthyretin in the choroid plexus: implications on cognitive function and amyloid beta deposition in an Alzheimer disease mouse model
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/SAU-ORG/113329/2009

Autoregulation in acute stroke
Maria Isabel de Sousa Rocha
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/113516/2009

A multi-dimensional approach of early life stress impacts: crosstalk between neuroendocrine and immune systems
Ana Raquel Marcelino Mesquita
Universidade do Minho (UM)

PTDC/SAU-ORG/113530/2009

Mitochondrial Dysfunction in Mitochondrial Long-Chain Fatty Acid ß-Oxidation Disorders: Role of Fatty Acid Intermediates and Potential Therapeutic Strategies
Maria de Fátima Vieira Ventura
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/113540/2009

Regulatory T cells as a target for the treatment of autoimmune diseases
Iris Caramalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/113545/2009

Animal model of chronically dysfunction of ubiquitin-proteasome system: Implications for age-related macular degeneration
Henrique Girao
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ORG/113617/2009

Exploiting the molecular basis underlying an aberrant vascular niche in Multiple myeloma
Sérgio Dias
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/113874/2009

Does the adenosine signalling pathway protect the heart in an animal model of pulmonary hypertension?
Ana Patrícia Fontes de Sousa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ORG/113998/2009

The relevance of lipid metabolism on the evolution of hepatitis C viral infection and in treatment response
Maria Fátima Soares Silveira Serejo Leal da Silva
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ORG/114025/2009

Extracellular matrix alterations in bone marrow: cues for bone marrow dysfunction?
Ana Sofia Monteiro Mendes Cachaço
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ORG/114046/2009

THE IMPACT OF CORNEAL REFRACTIVE THERAPY ON ADULT MYOPIA PROGRESSION AND INFLUENCE OF BIOMECHANICAL CORNEAL PROPERTIES
Jorge Manuel Martins Jorge
Universidade do Minho (UM)

PTDC/SAU-ORG/114083/2009

Molecular determinants of microglial activation and neuronal dysfunction in in vivo models of Parkinson´s disease
Maria Teresa Albuquerque Santos Faria Pais
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/114275/2009

WATER TRANSPORT AND IONIC TRANSLOCATION IN CELLS FROM THE HUMAN SEMINIFEROUS EPITHELIUM - BUILDING A MATHEMATICAL MODEL.
CARLOS PEDRO FONTES OLIVEIRA
Universidade da Beira Interior (UBI)

PTDC/SAU-ORG/114282/2009

Infertility associated to Type I Diabetes: metabolic regulation and membrane transport
CARLOS PEDRO FONTES OLIVEIRA
Universidade da Beira Interior (UBI)

PTDC/SAU-ORG/114285/2009

Hormonal Regulation of Ion Transporters in Sertoli Cells: A Possible Role for Estrogens in Spermatogenesis?
CARLOS PEDRO FONTES OLIVEIRA
Universidade da Beira Interior (UBI)

PTDC/SAU-ORG/114476/2009

From Human Proteomics to Development of Therapeutic Targets for Lung Hypoplasia
Jorge Manuel Nunes Correia Pinto
Universidade do Minho (UM)

PTDC/SAU-ORG/114519/2009

Functional, cellular and molecular evaluation of glucagon-like peptide 2 administration effects on animal model of intestinal anastomosis
Francisco José Franqueira de Castro e Sousa
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-ORG/114601/2009

Pathophysiological mechanisms underlying the progression to systemic inflammation, pulmonary hypertension, myocardial dysfunction and cachexia in experimental chronic obstructive pulmonary disease
Joaquim Adelino Correia Ferreira Leite Moreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/114735/2009

Myocardial infarction treatment by selective arterialization of coronary veins
Artur Manuel Perez Neves Aguas
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ORG/114924/2009

Systemic Vibration induced by chronic exposure to very low and infrasonic industrial noise: Resonance and Cavitation of Viscera
MARIA JOÃO FEYTOR PINTO RODRIGUES DE OLIVEIRA DE MEIRELES MOREIRA
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ORG/115219/2009

Predictive factors of dysfunction and long term renal allograft loss
Isabel Maria da Silva Fonseca
Centro Hospitalar Universitário do Porto (CHP/MS)

PTDC/SAU-ORG/115240/2009

The neurobiology of anxiety: the amygdala and bed nucleus of the stria terminalis as targets of anxiolytic drugs
JOSÉ MIGUEL GOMES MOREIRA PÊGO
Universidade do Minho (UM)

PTDC/SAU-ORG/115259/2009

Aldosterone and mineralocorticoid receptor: new targets for the prevention of neuronal death in diabetic retinopathy?
Paulo Fernando Martins dos Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/115493/2009

Erithropoietin production and pre-fibrillar amyloid toxicity
Paulo Manuel de Castro Pinho e Costa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ORG/115573/2009

AIMDrill - Assisted Intramedullary Medical Drill
Ana Rosanete Lourenço Reis
INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI/UP)

PTDC/SAU-ORG/115705/2009

TTR amyloid fiber formation in vivo - beyond genetic factors
Goncalo martins Conde da Costa
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ORG/116016/2009

Humoral and tissue Doppler characterization of the failing heart of infants with congenital diaphragmatic hernia
Maria João Ribeiro Leite Baptista
Universidade do Minho (UM)

PTDC/SAU-ORG/116047/2009

TRENDEASES :: Age-related and region-specific changes of TRace ElemeNt levels in human brain. Focus on changes in relation to NeuroDegenerative disEASES
AGOSTINHO ALMIRO DE ALMEIDA
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ORG/116180/2009

MyOPAF- Associated factors to Myopia onset and progression
Jorge Manuel Martins Jorge
Universidade do Minho (UM)

PTDC/SAU-MET/110323/2009

Disorders on the Glycolytic and Pentose Phosphate Pathways of the Red Blood Cell - how do they affect Plasmodium infection?
Ana Paula Martins dos Reis Arez
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MET/110563/2009

Antiangiogenic potential of Cynara cardunculus polyphenolic rich extracts on hepatocellular carcinoma
MARIA DE FÁTIMA PEREIRA DUARTE RICARDO
Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo (CEBAL)

PTDC/SAU-MET/110931/2009

Berry fruit consumption: polyphenols bioavailability, effects on plasma redox status and plasma ex-vivo protection in a neurodegenartion cell model
Maria Cláudia Nunes dos Santos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MET/111274/2009

Postprandial signalling pathways of insulin sensitivity: a translational study
Maria Paula Borges de Lemos Macedo
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-MET/111351/2009

Metabolic profile and adipokines in mild cognitive impairment - influence on conversion to Alzheimer´s disease
Armando José Nunes Harrington Sena
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-MET/111483/2009

S.O.S.- Survey on Obesity using Saliva - Taste perception and salivary function
Maria Isabel Augusta Cortes do Carmo
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-MET/111935/2009

Association between components of Metabolic Syndrome, dietary intake and adiposity in obese children
Flora Correia
Faculdade de Ciências da Nutrição e Alimentação (FCNA/UP)

PTDC/SAU-MET/112194/2009

Obesity and metabolic syndrome: amelioration of associated (western) diet through some portuguese natural mineral waters.
Maria João dos Reis Conceição Martins Almeida Ribeiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/112430/2009

In utero exposure to endocrine disruptors: metabolic impact in aldulthood
Maria Conceicao Costa Pinho Calhau
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/112464/2009

Gliptins therapeutics (monotherapy or under metformin association) for prevention of pancreatic degradation in type 2 diabetes - When start therapeutics?
Flávio Nelson Fernandes Reis
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-MET/112631/2009

Citrus fruits and cancer - last call
Cristina Maria Da Silveira e Silva Pereira Wilson
Universidade do Minho (UM)

PTDC/SAU-MET/112825/2009

From adipocyte cells and fat tissue explants to obese model responses: testing novel CLA isomers on fat modulation.
Paula Alexandra Lopes
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-MET/112893/2009

A randomized controlled trial of the efficacy and safety of different diet interventions for weight loss in subjects with asthma
André Miguel Afonso de Sousa Moreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/113227/2009

CARNITAGE: Carnitine neuroprotection mechanisms during ageing
Pedro Miguel Martins de Almeida Melo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MET/113374/2009

Early Feeding Skills (EFS) validation for the Portuguese preterm newborn Population
João Paulo Maroco Domingos
ISPA, CRL (ISPA)

PTDC/SAU-MET/113763/2009

BioAmineRisk: Biologically Active Amines in Taditional Portuguese Foods: Risk Analysis
Olivia Maria Castro Pinho
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-MET/113927/2009

Unraveling the role of estrogens and xenoestrogens in adipose tissue-originated inflammation
Maria do Rosário Barbosa Monteiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/113995/2009

Interplay between sirtuins and nitric oxide: is PGC-1alpha a common mediator for mitochondrial biogenesis?
Anabela Pinto Rolo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MET/114029/2009

Active immunotherapy against autologous ghrelin: a novel target for obesity treatment
LÍDIA MARIANA RODRIGUES PEREIRA MONTEIRO
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-MET/114167/2009

Influence of Polymorphic Variants of Lipid Metabolism and Metabolic Genes in Colorectal Cancer Development
Lina Maria Rodrigues Carvalho
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-MET/114659/2009

PSYMET - Psychiatric ilness, treatment and their role on metabolic parameters
Rui Manuel Bento Almeida Coelho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/115190/2009

Mitochondrial dysfunction in fatty acid oxidation disorders: a proteome approach for improved analysis.
Laura Ferreira Teixeira Vilarinho
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-MET/115217/2009

Remodeling of gut - adipocyte - beta-cell communication in type 2 diabetes after bariatric surgery: identification of new therapeutic targets.
Raquel Maria Fino Seiça
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-MET/115222/2009

Metabolic syndrome and breast cancer: identification of molecular markers for diagnosis/prognosis and therapy
Raquel Maria Fino Seiça
Faculdade de Medicina da Universidade de Coimbra (FM/UC)

PTDC/SAU-MET/115315/2009

Nutritional Factors on Glaucoma: Risk Benefits of Selenium Intake
António Joaquim Rodrigues Castanheira Dinis
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-MET/115404/2009

Bone Clinic - Optimization of biomarkers of bone turnover in orthopaedic research and in osteoporosis
Maria Isabel Ribeiro Dias
Universidade do Minho (UM)

PTDC/SAU-MET/115461/2009

Fructo-oligosaccharides and fibre in home enteral nutrition: influence on microbiota and gastrointestinal quality of life in patients with head or neck cancer
Maria da Graça Miguel
Universidade do Algarve (UAlg)

PTDC/SAU-MET/116121/2009

Motivational Infrastructure and Healthy Lifestyle Intervention with a Particular Emphasis on School Children and their Families to Planning, Promoting and Sharing Good Practice in an Urban and Regional Level
Pedro Orlando Rodrigues
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-MET/116192/2009

Physical exercise and mitochondrial abnormalities in diabetes and in insulin resistance. Special reference to mitochondrial-mediated apoptotic cell death
António Alexandre Moreira Ribeiro de Ascensão
Faculdade de Desporto da Universidade do Porto (FADE/UP)

PTDC/SAU-GMG/110785/2009

New E-cadherin RNAs: the dark side of a tumour suppressor gene
Carla Oliveira
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-GMG/111761/2009

Dissecting nerve regeneration and the neuritogenic activity of TTR.
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/112577/2009

Molecular genetics of neurodevelopmental disorders: a systematic approach using C. elegans
Ana João Gomes Rodrigues
Universidade do Minho (UM)

PTDC/SAU-GMG/112617/2009

Screening of therapeutic compounds in a C. elegans model of Machado-Joseph disease
Patrícia Espinheira de Sá Maciel
Universidade do Minho (UM)

PTDC/SAU-GMG/113795/2009

The Transcriptome of the Oncogenic HOXA9 Homeoprotein in Human Glioblastoma: Characterization and Functional Significance
Bruno Costa
Universidade do Minho (UM)

PTDC/SAU-MIC/111387/2009

Pre-clinical assays of a GAPDH-based vaccine against Group B Streptococcus infection
Paula Ferreira
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-MIC/111581/2009

Characterization of two new Listeria monocytogenes virulence genes up-regulated during in vivo infection: role of cadmium efflux system and teichoic acid decoration in Listeria pathogenicity
Didier Cabanes
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MIC/115598/2009

The role of adenosine and A2A receptor in anti-Candida albicans immunity
Teresa Maria Fonseca de Oliveira Gonçalves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-IMU/110116/2009

Unveiling the thymic interleukin 7 niche in vivo - A framework to study the cellular and molecular control of a master regulator of T lymphopoiesis.
Nuno Miguel de Oliveira Lages Alves
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/109955/2009

Cell to cell transport of alpha-synuclein in Parkinson´s Disease. The progression factor?
Manuel Joaquim Marques Garrido
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/110602/2009

Regulation by phosphorylation of ataxin-3, the mutated protein in Machado Joseph Disease
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/110990/2009

Mitochondrial preconditioning: potential neuroprotective effect in Alzheimer's disease
PAULA ISABEL DA SILVA MOREIRA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/111980/2009

Deciphering neurotrophic signaling pathways mediated by the Alzheimer's Amyloid Precursor Protein, APP
Sandra Isabel Moreira Pinto Vieira
Universidade de Aveiro (UA)

PTDC/SAU-NMC/112183/2009

iCALP - Identification of the physiological roles of calpains in the control of cell proliferation and migration in the central nervous system
Inês Maria Pombinho de Araújo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/113934/2009

MECHANISTIC LINKS BETWEEN STRESS-INDUCED MOOD AND COGNITIVE DYSFUNCTION - THE PATH FROM DEPRESSION TO ALZHEIMER'S DISEASE
Ioannis Sotiropoulos
Universidade do Minho (UM)

PTDC/SAU-NMC/114800/2009

Microarray based identification of estrogen and androgen responsive genes in rat choroid plexus
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/SAU-NMC/114810/2009

Localization and metabolism of APP controlling synaptic degeneration in animal models of Alzheimer's disease
Catarina Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/115700/2009

The role of the vagus nerve and brainstem pathways in the mechanisms of gastro-intestinal hormones induced weight loss
LÍDIA MARIANA RODRIGUES PEREIRA MONTEIRO
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-NMC/115865/2009

A lipidomic approach of Alzheimer`s disease - Study of lipid profile changes in brain mitochondria
Romeu António Videira
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/SAU-NSC/110954/2009

The brain during chronic pain: how mu-opioid receptors may enhance nociceptive transmission?
Isaura Ferreira Tavares
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NSC/111814/2009

Stress and risky decision making
JOÃO JOSÉ FERNANDES CARDOSO DE ARAÚJO CERQUEIRA
Universidade do Minho (UM)

PTDC/SAU-NSC/113471/2009

A visual view on the reading deficit in dyslexia
Marieke van Asselen
Universidade de Coimbra (UC)

PTDC/SAU-NSC/115506/2009

Role of ascending serotoninergic pathways in epileptogenesis and epilepsy-related brain damage
NIKOLAY VSEVOLODOVICH LUKOYANOV
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-BMA/111233/2009

Nanohydroxyapatite antibacterial surfaces to prevent biofilm associated bone infection (NaNOBiofilm)
MARIA PIA DE MELO ALVIM FERRAZ TAVARES
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/113030/2009

GIANTCELL - The modulation of macrophages to resolve inflammatory reactions to biomaterials through the induction of the M2 phenotype
Maria Judite Tavares Moreira Novais Barbosa
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/114059/2009

Intracellular Drug Delivery Systems and Tissue Engineering as a Combinatory Approach for Spinal Cord Injury Regeneration
António José Braga Osório Gomes Salgado
Universidade do Minho (UM)

PTDC/SAU-BMA/114482/2009

Development of a novel therapeutic strategy for pancreatic cancer involving a concerted action of gene therapy and chemotherapeutic agents
Henrique Manuel Santos Faneca
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ENB/110354/2009

Angiogenesis in Diabetic Retinopathy: Integrating Experiments and Modelling
Rui Travasso
Associação para o Desenvolvimento do Departamento de Física da Universidade de Coimbra (ADDFUC/FCT/UC)

PTDC/SAU-ENB/111139/2009

3D retinal vascular network from Optical Coherence Tomography data
Pedro Miguel Picado de Carvalho Serranho
Universidade de Coimbra (UC)

PTDC/SAU-ENB/113151/2009

Development of new drug delivery systems based on bisnaphthalimidopropyl derivatives compounds liposomal formulation for pancreatic cancer and leishmaniasis drug therapy
Sofia Lima
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ENB/113696/2009

Generation of cord blood-derived Induced Pluripotent Stem cells using a non-viral approach and their differentiation into cardiomyocytes- iPSCardio
Ricardo Neves Pires das Neves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ENB/114786/2009

Nano-electrode arrays Biosensor for Early and Decentralized Breast-Cancer Diagnosis
Hendrikus Nouws
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ENB/114951/2009

3d BCT - 3D Models for Aesthetic Evaluation and Prediction of Breast Cancer Interventions
Jaime Santos Cardoso
Instituto de Engenharia de Sistemas e Computadores do Porto (INESC Porto/FE/UP)

PTDC/SAU-ENB/115179/2009

MaxBone - Maxillofacial Reconstruction using regenerative therapies: from Stem Cells to pre-Clinical Trials
Nuno Neves
Universidade do Minho (UM)

PTDC/SAU-ENB/115792/2009

Dose distribution mapping and Monte Carlo simulations in CT-fluoroscopy
João António Miranda dos Santos
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-EPI/113424/2009

The Bone Decadein Portugal: spatio-temporal trends in the incidence of hip fractures
Maria de Fátima Rodrigues Pereira de Pina
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-EPI/115151/2009

Health status and preferences of the Portuguese population
Pedro Augusto Melo Lopes Ferreira
Centro de Estudos e Investigação em Saúde da Universidade de Coimbra (CEISUC)

PTDC/SAU-EPI/115254/2009

Evaluating the best way of assessing adolescents' obesity as predictor of cardiovascular risk in adulthood
Elisabete Ramos
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-SAP/112908/2009

COSTProMed - Communication Skills Teaching Programme in Medicine
Maria Amélia Duarte Ferreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-SAP/113196/2009

ANTIPEP - CONTROL OF MICROBIAL ADHESION AND BIOFILM FORMATION ON ABIOTIC MEDICAL SURFACES THROUGH ANTIMICROBIAL PEPTIDES-BASED PRODUCTS
Maria Olívia Baptista de Oliveira Pereira
Universidade do Minho (UM)

PTDC/SAU-SAP/114855/2009

Alkaline hydrolysis of health care infectious wastes
Manuel Afonso Magalhães Fonseca Almeida
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-TOX/110952/2009

Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction
Paulo Jorge Gouveia Simoes Da Silva Oliveira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/114166/2009

Interaction of aspirin with antihypertensive drugs - impact on renal oxidative stress, inflammation, local renin-angiotensin system activation and blood pressure control
Teresa Sousa
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-TOX/114253/2009

Cross-talk between chronic renal failure, inflammation and erythropoiesis in resistance to recombinant human erythropoietin therapy
Flávio Nelson Fernandes Reis
Universidade de Coimbra (UC)

PTDC/SAU-TOX/114549/2009

Potential predictive biomarkers of anti-RTKs therapy response in gliomas: An “in vitro” and “in vivo” Study
RUI MANUEL VIEIRA REIS
Universidade do Minho (UM)

PTDC/SAU-TOX/115597/2009

ASTROCYTE-MICROGLIA CROSSTALK IN ASTROGLIOSIS: MODULATION BY P2 RECEPTORS
Maria da Glória Correia da Silva Queiroz
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/110848/2009

Functional, molecular and pharmacological studies of p53 family proteins: from yeast to human cells
Lucília Helena Ataíde Saraiva
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/111414/2009

Developing strategies to understand antibiotics influx at a molecular level
Alberta Paula Lobo Machado Gameiro-dos-Santos
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/112277/2009

InVitroBrain - Development of a humanized dynamic in vitro blood-brain barrier model and a vesicle-based barrier for brain penetration of drugs incorporated in lipid nanoparticles - Closing the gap between in vivo and in vitro properties
Domingos de Carvalho Ferreira
Faculdade de Farmácia da Universidade do Porto (FF/UP)

PTDC/SAU-FAR/113100/2009

NanoLaseRelief: Integrando nanotecnologias no alívio da dor na terapia laser de lesões vasculares
Eliana Souto
Fundação Ensino e Cultura Fernando Pessoa (FECFP)

PTDC/SAU-FAR/115044/2009

Development of a mucosal hepatitis B vaccine: Design and mechanistic studies of a prototypic multi-component polymeric delivery system.
Olga Maria Fernandes Borges
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ONC/110294/2009

Tumour spectrum in Hereditary Diffuse Gastric Cancer
Raquel Seruca
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/112511/2009

Effect of radio- and chemotherapy on cancer cell invasion: the role of macrophages
Maria José Cardoso Oliveira
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-ONC/112671/2009

EFFECT OF THE MICROENVIRONMENT ON POST-TRANSLATIONAL MODIFICATIONS OF ESTROGEN RECEPTORS
Luisa Alejandra Helguero
Universidade de Aveiro (UA)

PTDC/SAU-ONC/112917/2009

Dissecting the link between oncogene activation and mitotic checkpoint function by human Tpr - implications for the mechanism of tumorigenesis
Helder Jose Martins Maiato
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ONC/115513/2009

Identification of novel target genes in microsatellite unstable brain tumours
RUI MANUEL VIEIRA REIS
Universidade do Minho (UM)

PTDC/SAU-BID/112250/2009

Functional genomic analysis of the Drosophila early eye specification gene network
Paulo Jorge Sousa Nunes Pereira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/110112/2009

The crosstalk between lipid antigen presentation and the pathogenic mechanisms of Lysosomal Storage Diseases
Maria de Fátima Matos Almeida Henriques de Macedo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/110683/2009

Role of the ghrelin/obestatin system in the aqueous humor drainage mechanisms. Patophysiologic relevance.
Amandio Rocha Sousa
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/111313/2009

Molecular basis of nervous system dysfunction on amyloid neuropathies
Maria João Gameiro de Mascarenhas Saraiva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/112406/2009

Consequences and mechanisms behind plasmalogen deficiency
Pedro Miguel Teixeira Brites
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/113542/2009

Tumorigenesis as a working model for the physiological role of HIF-1alpha degradation by chaperone-mediated autophagy
Henrique Girao
Universidade de Coimbra (UC)

PTDC/SAU-MET/111398/2009

Role of the intestine in promoting the lipogenic effects of fructose
John Griffith Jones
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MET/113011/2009

Protection from iron toxicity by the immune system: cells, proteins and mechanisms
Idílio Jorge Matias Pereira Pinto
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MET/113415/2009

Role of monocarboxylate transporters (MCTs) in the metabolism of prostate cancer
Maria de Fátima Monginho Baltazar
Universidade do Minho (UM)

PTDC/SAU-MET/115635/2009

New therapeutic approaches for the treatment of vascular complications in type 2 diabetes and metabolic syndrome
Cristina Maria Tristão Sena
Universidade de Coimbra (UC)

PTDC/SAU-MET/116119/2009

Nutritional modulation of inflammation, oxidative stress and apoptosis associated with cardiac cachexia.
Roberto Liberal Fernandes Roncon de Albuquerque
Faculdade de Medicina da Universidade do Porto (FM/UP)