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R&D Projects

Call for Proposals for Scientific Research and Technological Development Projects in all Scientific Domains - 2010

Painel de Avaliação da área das Ciências da Saúde - 2010

Coordination

Fernando Lopes da Silva
Marc Mareel
Ghent University Hospital, Belgium

Evaluation

Ad Geurts van Kessel
Radboud University Nijmegen Medical Centre, Netherlands
Andrew Westwell
Cardiff University, United Kingdom
Anna Maria Bianchi
Politecnico di Milano, Italy
Bruno Bujoli
Chimie Et Interdisciplinarité: Synthèse Analyse Modélisation/CEISAM, Université de Nantes/UMR 6230, France
Carlos Fitzsimons
Swammerdam Institute for Life Sciences, Netherlands
Christoph Tang
Imperial College London, United Kingdom
Dagmar Fischer
Friedrich-Schiller-Universität Jena, Germany
Derek Macallan
St George's, University of London, United Kingdom
E.M. Hol
Netherlands Institute for Neuroscience - Amsterdam, Netherlands
Fernando Giraldez Orgaz
UNIVERSITAT POMPEU FABRA, Spain
Francisco Bolumar
Universidad de Alcalá, Spain
Geert Martens
Vrije Universiteit Brussel - Brussels Free University, Belgium
Gerard J te Meerman
University Medical Center Groningen, Netherlands
Herman Waldmann
Sir William Dunn School of Pathology, United Kingdom
Humphrey Hodgson
Medical School - UCL, United Kingdom
Jean-Michel Bouler
INSERM UMR 791 - Université de Nantes, France
Jochen Klein
Goethe University of Frankfurt, Germany
Lionel Ginsberg
Clinical Neurology - University College London, United Kingdom
Louis Lemieux
UCL Institute of Neurology, United Kingdom
Luca Mainardi
Dipartimento di Bioingegneria - Politecnico di Milano, Italy
Marc Bracke
Ghent University, Belgium
Martin Prins
Maastricht University Medical Center, Netherlands
Maurice Zeegers
University of Birmingham, United Kingdom
Maxime GUYE
Université de La Méditerranée, France
Miguel Delgado
Universidad de Jaén, Spain
Raymond Macallister
UCL - London, United Kingdom
Robert Hofstra
University Medical Center Groningen (UMCG), Netherlands
Roberto Sassi
Università degli Studi di Milano, Italy
Stephen Hiscox
Welsh School of Pharmacy, Cardiff University, United Kingdom
Stephen Paul Hilary Alexander
University of Nottingham, United Kingdom
Willem Kamphuis
Netherlands Institute for Neuroscience-KNAW, Netherlands

Projects assigned

PTDC/SAU-GMG/116651/2010

The role of epigenetic programming in addiction vulnerability
Ana João Gomes Rodrigues
Universidade do Minho (UM)

PTDC/SAU-GMG/116717/2010

Phenotypic dimensions in Psychosis
Ana Telma Pereira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-GMG/116833/2010

Evaluating the role of proteolysis in the male reproductive system through the study of KLK (19q13.4) and WFDC (20q13) gene clusters.
Susana Seixas
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-GMG/117046/2010

Splicing therapeutic approaches for patients affected by lysosomal storage disorders
Sandra Catarina da Conceição Alves
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-GMG/117213/2010

Understanding renal tubular glucose transport: the role of SGLT2 and the impact of isoforms and mutants in the cotransporter activity.
Joaquim Fernando Tomaz Rodrigues Moita Calado
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/117591/2010

The functional link between HFE and Hepcidin - its contribution to iron metabolism regulation in normal and in iron overload conditions
MARIA PAULA DUARTE FAUSTINO GONÇALVES
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-GMG/117674/2010

Portuguese cancer-predisposing founder mutations: contribution to disease burden and predictive value of somatic genetic changes
Manuel António Rodrigues Teixeira
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-GMG/117927/2010

Searching new SCAs genes: an exome sequencing approach
Maria da Conceição Felix Bettencourt
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/118140/2010

The molecular pathogenesis of chromosome translocation-associated “cis-ruption” disorders
Dezso David
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-GMG/118180/2010

Splicing and stochasticity in programmed cell death decisions
Maria Carmo-Fonseca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/118371/2010

Genetic and functional study of neurotransmission mechanisms associated with migraine susceptibility
Carolina Lemos
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/118502/2010

Functional genomics for monogenic dyslipidaemia
Mafalda Bourbon
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-GMG/118633/2010

Epigenomics and NoncodingRNomics of Alzheimer´s Disease
Madalena Cristina da Rocha Martins
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/118637/2010

T-cell ncRNomics in Systemic Lupus Erythematosus
Madalena Cristina da Rocha Martins
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-GMG/118688/2010

Genetic susceptibility to obesity: aCGH study in a pediatric population
Henedina da Conceição Araújo Antunes
Universidade do Minho (UM)

PTDC/SAU-GMG/118691/2010

Study of the role of acid sphingomyelinase in the pathogenesis of lysosomal storage diseases of ceramide
Maria Gil Roseira Ribeiro
Fundação Ensino e Cultura Fernando Pessoa (FECFP)

PTDC/SAU-GMG/118766/2010

Unravelling hemoglobinopathies: characterization of the structural and functional patterns presented by altered human hemoglobin.
Daniela Maria Barroso de Moura Cipreste Vaz
Instituto Politécnico de Leiria (IPLeiria)

PTDC/SAU-GMG/118904/2010

How an upstream open reading frame regulates human erythropoietin gene expression
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/119097/2010

Nuclear metabolism of nonsense transcripts
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/119175/2010

New functions of transthyretin - a genetic approach
Maria João Gameiro de Mascarenhas Saraiva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/119221/2010

Study of the association between IL-4, IL-4R and IL-13 gene-gene interactions and IgE levels in human atopy
Luis Manuel Taborda Barata
Universidade da Beira Interior (UBI)

PTDC/SAU-GMG/119246/2010

Polg, unfolding the regulatory regions
Lígia Susana Vieira de Almeida
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-GMG/119586/2010

A novel Rac1/PAK1/BCL-6 pathway to regulate gene expression: genome-wide screening for target genes
Paulo Henrique Carrasquinho de Matos
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/119593/2010

mtDNA dysfunction as a biomarker in polyglutamine (Poly-Q) disorders
Maria Manuela de Medeiros Lima
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/119629/2010

Identification of Novel Genomic Regions associated with MAC (Microphthalmia, Anophthalmia and Coloboma)
ISABEL MARIA MARQUES CARREIRA
Universidade de Coimbra (UC)

PTDC/SAU-GMG/119791/2010

Investigating microRNA-targeted Proteome involved in the early events of hepatocellular carcinoma pathogenesis
Deborah Penque
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/119822/2010

Unravelling the genetics of familial thyroid cancer: candidate gene and genome-wide linkage approaches
Branca Maria Prudêncio Limón Cavaco
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/119871/2010

Cardiovascular diseases in Azores: epidemiology and genetic risk
Cláudia Margarida Aguiar Castelo Branco
Hospital do Divino Espírito Santo de Ponta Delgada, EPE (HDESPD, EPE)

PTDC/SAU-GMG/120065/2010

Integration of transcriptomic and proteomic approaches toward the discovery of anti-TNF alpha therapy biomarkers in ankylosing spondylitis.
Jaime Branco
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/120285/2010

Genetic susceptibility and oral rehabilitation with dental implants
Paula Cristina dos Santos Vaz Fernandes
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-GMG/120382/2010

Etiology of Attention deficit/hyperactivity disorder: targeting new genes to improve therapy
Alda Maria Abreu Cardoso
Universidade de Coimbra (UC)

PTDC/SAU-GMG/120413/2010

Genoma 2.0
Luís Tiago Ferreira Romero Magalhaes
Universidade do Algarve (UAlg)

PTDC/SAU-GMG/120605/2010

Identification of MEF2C target genes by genome-wide/functional analysis
Natércia Conceição
Centro de Ciências do Mar (CCMar)

PTDC/SAU-GMG/120636/2010

MicroRNAs profile expression in Hepatocellular Carcinoma: Potential prognostic and therapeutic value
Sílvia Sousa Neves
Universidade de Coimbra (UC)

PTDC/SAU-GMG/120724/2010

Gene Expression Profiling in Autism Spectrum Disorder
Inês Susana Pires Carreira da Conceição
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-GMG/120778/2010

Molecular genetics of monogenic diabetes due to pancreatic beta-cell defects
Manuel Lemos
Universidade da Beira Interior (UBI)

PTDC/SAU-GMG/120938/2010

Fanconi Anemia: searching for prevention against chromosome instability
Maria Beatriz Beça Gonçalves Porto e Vasconcelos
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-GMG/120947/2010

Biomarker Discovery for Obstructive Sleep Apnea Syndrome
Maria Cristina de Brito Eusébio Bárbara Prista Caetano
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/121304/2010

Translating epigenetic regulation in clinical answers to hematopoietic malignancies
Paula Cristina da Costa Alves Monteiro Ludovico
Universidade do Minho (UM)

PTDC/SAU-GMG/121350/2010

Oxidative Stress vs Epigenetics - Role in susceptibility and therapy response in hemato-oncology
Ana Bela Sarmento Ribeiro
Universidade de Coimbra (UC)

PTDC/SAU-GMG/121353/2010

The genetic basis beyond mitochondrial DNA deletions causing Kearns-Sayre syndrome
Laura Ferreira Teixeira Vilarinho
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-GMG/121546/2010

Bigenomic Interaction and Genotype-Phenotype Correlation in Leber´s Hereditary Optic Neuropathy
Manuela Grazina
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-GMG/121548/2010

Modeling T-cell pathology in human SLE by cell type-specific expression profiles
Constantin Fesel
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-GMG/121716/2010

Ischaemic Heart Disease (myocardial ischaemia): possible role of the genetic variants of MMP and TIMP in the Myocardial Perfusion Scintigraphy.
Durval C Costa
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-GMG/121824/2010

Interaction between cardiovascular and rare diseases: can the lysosome be a connecting link?
Sonia Alexandra Vieira e Pinho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-GMG/121828/2010

MicroRNA Target identification and biomarker validation in breast cancer
José Rueff
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/121844/2010

Deciphering the role of ineffective erythropoiesis in iron metabolism decontrol in iron-loading anemias
MARIA PAULA DUARTE FAUSTINO GONÇALVES
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-GMG/121987/2010

Modulation of Pyruvate Dehydrogenase Complex: chaperones on the road to novel therapeutic interventions
Isabel Maria Antolin Martins-de-Carvalho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-GMG/122299/2010

Characterization of ER-quality control for the F508del-CFTR protein: potential therapeutic targets for cystic fibrosis
Margarida Sofia Pereira Duarte Amaral
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-GMG/122535/2010

MicroRNAs: potential biomarkers for resistance to tyrosine kinase inhibitors in Chronic Myeloid Leukemia
Marta Luísa Gromicho Morgado Silva
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-GMG/122592/2010

microRNA regulation in prostate cancer through androgen receptor and c-Myc signaling
Rui Manuel Ferreira Henrique
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-GMG/122831/2010

Genetic determinants of resistance/susceptibility to Mycobacterium ulcerans infection: a population based study - Buruli Ulcer Biological Specimens Bank
Alexandra Gabriel Fraga
Universidade do Minho (UM)

PTDC/SAU-GMG/122912/2010

NITRIC OXIDE METABOLISM and CARDIOPULMONARY BYPASS- A GENETIC, TRANSCRIPTOMIC AND PROTEOMIC APPPROACH
José Fragata
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-MIC/116592/2010

Prevention and Diagnosis of Peritoneal Dialysis-related infections
Isabel João Soares da Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MIC/116649/2010

TrypSysBio - A systems biology approach to uncover key glycan-processing enzymes essential for complex N-glycosylation in Trypanosoma brucei
João Alexandre Guarita da Silva Rodrigues
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/116716/2010

Clinical relevance of multiple genetic markers in Pneumocystis jirovecii pneumonia (PcP): New high-throughput methodologies for molecular epidemiology and diagnosis.
Olga Maria Guerreiro de Matos
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/116866/2010

Pregnancy malaria in the mouse: resolving the host-parasite interface.
CARLOS AUGUSTO GOMES BARBOSA DA PENHA GONÇALVES
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MIC/116960/2010

Depletion of latent HIV from cellular reservoirs by modulation of host´s intracellular pathways
Mariana Canelhas Palminha Santa Marta
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MIC/117060/2010

Utilization of host cell resources by the malaria parasite in the liver
Miguel Prudêncio
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/117614/2010

MORPHCOL - Clinical relevance of colony morphology variants on mono- and polymicrobial biofilm formation, resistance and virulence
Maria Olívia Baptista de Oliveira Pereira
Universidade do Minho (UM)

PTDC/SAU-MIC/117739/2010

LLSTREV-Role of Listeriolysin S in stress response and virulence
Maria Leonor Faleiro
Universidade do Algarve (UAlg)

PTDC/SAU-MIC/117813/2010

Amoebae as reservoirs of agents of nosocomial disease in Portuguese hospitals
António Pedro Alves Matos
Hospital de Curry Cabral, E.P.E. (HCC)

PTDC/SAU-MIC/118009/2010

Consequences of defective autophagy in Crohn´s disease macrophage responses to bacterial infection
Amélia Maria Marques da Silva Rodrigues Sarmento Assunção
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MIC/118016/2010

The role of Rab GTPases during the infectious cycle of Chlamydia trachomatis
Luís Jaime Gomes Ferreira da Silva Mota
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-MIC/118249/2010

Disclosure of protein-protein interactions in vertebrate cells infected with pathogenic arboviruses.
Ricardo Manuel Soares Parreira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/118553/2010

Mechanisms of modulation of the host´s iron homeostasis by chronic mycobacterial infection.
Maria Salomé Gomes
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MIC/118614/2010

ENCCRYPT - Environmental and clinical cryptic Aspergillus species, their molecular characterization, distribution and health impact
Raquel Sabino
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MIC/118902/2010

Role of Ferritin H Chain in Severe Sepsis: Establishment of Host Tolerance to Polymicrobial Infection.
Rasmus Larsen
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-MIC/118964/2010

AcinetoRisk-Acinetobacter and public health: Risks posed by community and hospital strains
Paula Cristina Maia Teixeira
Universidade Católica Portuguesa (UCP)

PTDC/SAU-MIC/119133/2010

Mycobacterium tuberculosis strains of Family Lisboa: Genomic diversity and virulence analysis
Isabel Portugal
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MIC/119352/2010

Estudo funcional do MecR2: um novo anti-repressor envolvido no controlo da expressão da resistência aos antibióticos beta-lactâmicos em estafilococos
Duarte Emanuel Soeiro Carvalho Oliveira
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-MIC/119422/2010

Peroxisomes in health and disease: unveiling the interplay between peroxisomes and viruses
Daniela Maria Oliveira Gandra Ribeiro
Universidade de Aveiro (UA)

PTDC/SAU-MIC/119446/2010

Optimization of the etiology of Acute Gastroenteritis - prospective multicenter study
Henedina da Conceição Araújo Antunes
Universidade do Minho (UM)

PTDC/SAU-MIC/119543/2010

The role of the thymus for an effective immune response against tuberculosis: the particular case of HIV-infected individuals
Margarida Correia-Neves
Universidade do Minho (UM)

PTDC/SAU-MIC/119558/2010

Malaria drug-resistance: development of a novel, clinically useful drug-sensitivity assay and evaluation of drug resistance in Angola.
Thomas Hänscheid
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/119707/2010

Study of cell-mediated response of DNA cytidine deaminases to HIV-2 infection
Isabel Maria Corrêa Calvente de Barahona
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-MIC/119783/2010

Manipulating expression of antiviral host factor APOBEC3G to overcome HIV-1 infection.
Inês Sampaio de Sousa Soeiro
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MIC/120095/2010

CHARACTERIZATION OF EPSTEIN-BARR VIRUS INFECTION IN ASSOCIATED CANCERS: CONTRIBUTING FOR AETIOLOGY, PROGNOSIS AND TREATMENT PREDICTION
HUGO MANUEL LOPES DE SOUSA
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-MIC/120209/2010

New strategies to control S. epidermidis biofilms
Domingas do Rosario Verissimo Jacinto Tavares de Oliveira
Universidade do Minho (UM)

PTDC/SAU-MIC/120422/2010

Role of H3.3 Histone epigenetic modulator during HIV infection
Isabel Maria Corrêa Calvente de Barahona
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-MIC/120514/2010

Análise funcional do Fsr e GelE-SprE e seu papel na virulência de enterococos e sua adaptação ao hospedeiro
Maria de Fátima Silva Lopes
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-MIC/120790/2010

Schistosoma haematobium and bladder cancer: possible carcinogenic effect through estrogen adduct-mediated pathway.
José Manuel Alves Correia da Costa
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-MIC/120865/2010

Assessment of public transports as reservoirs of multi-resistant Staphylococcus aureus and dissemination to the community.
Paulo Manuel Rodrigues Martins da Costa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-MIC/120871/2010

Portuguese artisanal foods: a source of emergent pathogenic yeasts and a threat to an ageing population?
Teresa Maria Fonseca de Oliveira Gonçalves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MIC/121077/2010

Study of ulcerogenic Helicobacter pylori strains isolated from children: a contribution to get insight the virulence of the bacteria.
Mónica Oleastro
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MIC/121180/2010

Mechanisms of translational repression in Plasmodium berghei
Kozlova Natalia Valerjevna
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/121367/2010

Phage Therapy: a new strategy for Buruli ulcer a difficult-to-treat, emergent and infectious disease
Gabriela Alexandra Trigo Branquinho
Universidade do Minho (UM)

PTDC/SAU-MIC/121451/2010

Molecular and cellular mechanisms underlying a detrimental role of TLR2 signalling during the innate immune response of Mycobacterium tuberculosis infection
António Gil Pereira de Castro
Universidade do Minho (UM)

PTDC/SAU-MIC/121638/2010

The genetic and immunological drivers of Anopheles gambiae resistance to Plasmodium infection.
Luis Filipe Lopes
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/121896/2010

PabraSec - Identification of virulence factors in the Paracoccidioides brasiliensis secretome
Marcus Henricus Johannes Sturme
Universidade do Minho (UM)

PTDC/SAU-MIC/121901/2010

Antimalarial efficacy of the artemisinin-based combination therapy (ACT) in Maputo
MARIA DE FÁTIMA CARVALHO NOGUEIRA
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/122082/2010

Pumilio-regulated gene expression of malaria during mosquito vector to mammalian host transmission
Gunnar Rudolf Mair
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MIC/122435/2010

New strategies for stopping HIV-1 through altered host-cell pathways: From virus entry to latency.
Joao Goncalves
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MIC/122551/2010

The relevance of new serologic markers for Pneumocystis jirovecii pneumonia (PcP) diagnosis
Olga Maria Guerreiro de Matos
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MIC/122780/2010

Functional compatibility of the replication complex as determinant of virulence in influenza virus
Helena Rebelo-de-Andrade
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-MIC/122788/2010

Molecular mechanisms associated with the development of antiviral drug resistance in seasonal and pandemic influenza viruses
Helena Rebelo-de-Andrade
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-MIC/122816/2010

Biofilms in diabetic foot: microbial virulence characterization and cross-talk of major isolates
Luis Manuel Morgado Tavares
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-MIC/122979/2010

The importance of Rlm1 transcription factor polymorphism in Candida albicans virulence using the invertebrate Drosophila melanogaster model
ANA PAULA FERNANDES MONTEIRO SAMPAIO CARVALHO
Universidade do Minho (UM)

PTDC/SAU-IMU/116529/2010

CD38 ectoenzyme: role in B cell autoimmunity?
Marta Susana de Almeida Viegas da Silva
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-IMU/116564/2010

Unraveling the pathways bridging IL-15 signaling and KIR expression on human CD8+ T cells
Fernando Aguilar Arosa
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-IMU/116809/2010

Role of IFNγ as modulator of Dendritic Cell recruitment
Zélia Maria Cordeiro da Silva
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-IMU/117177/2010

The role of Siglecs in the modulation of Dendritic Cell function in response to Burkholderia cepacia infection
Maria de Guadalupe Gonçalves Cabral
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-IMU/117225/2010

Regulation of Interleukin-17 and Interferon-g; cytokine gene expression during gd T cell differentiation
Anita Gomes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/118241/2010

A strategy to expand human regulatory T cells in vivo
Ana Espada de Sousa
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/118462/2010

The role of mast cells in impaired diabetic wound healing
EUGÉNIA MARIA LOURENÇO DE CARVALHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-IMU/118545/2010

Disentangling the activating effect of Polyclonal immunoglobulin on the lymphocyte compartments and repertoire diversity during immune reconstitution
Cristina Maria Godinho Pires João
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-IMU/118721/2010

Virtual histology in Inflammatory Bowel Disease
PEDRO MANUEL NARRA DE FIGUEIREDO
Universidade de Coimbra (UC)

PTDC/SAU-IMU/118852/2010

ImmunoTEC - Immunogenic potencial of adipose tissue- and starch-based tissue engineering constructs
Tírcia Susete Xavier Carlos Santos
Universidade do Minho (UM)

PTDC/SAU-IMU/118901/2010

Anti-high density lipoprotein (HDL) antibodies as a new risk factor for atherogenesis
José Delgado Alves
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-IMU/119345/2010

Detailing the alterations in the human T and B cell immunity induced by the treatment with polyclonal immunoglobulin in patients with secondary hypogammaglobulinemia
Cristina Maria Godinho Pires João
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-IMU/119691/2010

Guiding neutrophils in acute inflammation: an in vivo study on how hydrogen peroxide and chemokines concert their actions.
Angelo Miguel Silva Calado
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/120011/2010

Estrogen signaling in human obesity-related inflammation
Maria do Rosário Barbosa Monteiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-IMU/120225/2010

Regulation of germinal centre reaction by Foxp3+ follicular T cells
Luis Ricardo Silva Graca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/120300/2010

T-cell regulatory states in stable undifferentiated and in differentiated connective tissue diseases
Constantin Fesel
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-IMU/120352/2010

Role of Retinoic Acid in enteric lymphoid organogenesis
Henrique Veiga Fernandes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-IMU/120645/2010

ReSpond: Resveratrol loaded nanoparticles to modulate the immune response in spondyloarthropathies
Susana Gomes dos Santos
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-IMU/120673/2010

Drosophila antiviral immunity to natural infection
Luis Manuel Valla Teixeira
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-IMU/121719/2010

VALUE OF THE FLOW CYTOMETRY IN THE DIAGNOSIS AND IN UNDERSTANDING OF THE BIOLOGY OF MEMBRANE ERYTROCYTE DISORDERS
MARGARIDA LIMA
Centro Hospitalar Universitário do Porto (CHP/MS)

PTDC/SAU-IMU/121900/2010

Assessment of the prognostic value of soluble urokinase Plasminogen Activating Receptor (suPAR) at Intensive Care Unit discharge - prospective observational study
Joana Pedro Silva Silvestre
Centro Hospitalar de Lisboa Ocidental, EPE (CHLO)

PTDC/SAU-IMU/122953/2010

Impact of cellular therapy with CMV-specific CD4+ and CD8+ T cells following unrelated transplantation of hematopoietic progenitors
João Mascarenhas Forjaz de Lacerda
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/116872/2010

The role of miRNAs in the regulation of neuroinflammation mechanisms associated with Alzheimer´s disease
Ana Luísa Colaço Cardoso
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/116947/2010

Tauopathies as a model to investigate age-related glucocorticoid alterations in the hippocampus
Luisa Vaqueiro Lopes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/116953/2010

Downregulation of GABAergic synaptic transmission in brain ischemia - molecular mechanisms
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/117053/2010

Neuronal damage caused by amyloid beta peptide: loss of endogenous BDNF neuroprotection?
Maria José de Oliveira Diógenes Nogueira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/117142/2010

How do the barriers of the brain modulate aging and contribute to Alzheimer`s disease? A study on the choroid plexus/cerebrospinal fluid nexus.
Joana de Almeida Santos Pacheco Palha
Universidade do Minho (UM)

PTDC/SAU-NMC/117160/2010

Modulation of TTR stability and its impact in A-Beta levels, degradation, accumulation and toxicity: insights from in vitro, ex vivo and in vivo
Isabel dos Santos Cardoso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/117179/2010

Characterization of glycinergic transmission in hippocampus and its function in epilepsy
Cláudia Alexandra dos Santos Valente de Castro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/117217/2010

Unravelling the causes and consequences of methamphetamine-induced impairment of adult hippocampal neurogenesis: is neuropeptide Y a therapeutic tool?
Ana Paula Pereira da Silva Martins
Universidade de Coimbra (UC)

PTDC/SAU-NMC/117331/2010

Chronic effects of speedball- Role of chemical interactions between cocaine and opioids
MARIA TERESA MARTINS DA CUNHA OLIVEIRA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/117396/2010

Modulation of chromatin and transcription for splicing correction in Spinal Muscular Atrophy
SÉRGIO ALEXANDRE FERNANDES DE ALMEIDA
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/117455/2010

Mitochondria: the common upstream driver of amyloid beta and tau pathology in Alzheimer´s disease.
Sandra Morais Cardoso
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/117457/2010

Mitochondrial dynamics in Parkinson`s disease: validation of new therapeutic targets
Sandra Morais Cardoso
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/117520/2010

Amylin`s role in nociception: effects and mechanisms
Catarina Alexandra Soares Potes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/117538/2010

The transcriptional network of the zinc-finger protein Zeb1 and its function in neural stem/progenitor cells
Diogo Pinto da Cruz Sampaio e Castro
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NMC/117543/2010

Meningitis caused by Group B Streptococcus: the use of a novel experimental model mimicking the natural route of infection in humans to study the pathogenesis of this disease
Paula Ferreira
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-NMC/117583/2010

Monosynaptic convergence of somatic and visceral nociceptive afferents onto spinal lamina I neurons as mechanism of referred pain
Boris Safronov
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/117747/2010

EPPICS - Epigenetic mechanisms regulated by serine/ threonine protein phosphatases in the brain - effect on CYP46A1 expression and on other synaptic plasticity-related genes
Elsa Margarida Teixeira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/117877/2010

Preventing Memory Loss in Alzheimer`s Disease: Underlying Mechanisms and Therapeutic Targets of Tauroursodeoxycholic Acid
Cecília Maria Pereira Rodrigues
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/117946/2010

Inflammatory response, microglia and adult neurogenesis: a triad in Alzheimer`s disease?
Jorge Valero Gómez-Lobo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/118135/2010

S100B in central nervous system myelination: a cytoskeletal perspective
Adelaide Fernandes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/118237/2010

Enhancement of endogenous neurogenesis by nitric oxide following brain injury: Identification of S-nitrosylation targets
Inês Maria Pombinho de Araújo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/118259/2010

Parkinson´s disease and calcium (dys)homeostasis: relevance of purinergic receptors and Cav1.3 channels
Joana Estêvão de Matos
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-NMC/118455/2010

Drug design for treatment of neurological diseases: modulating complex function in the monoaminergic systems of the brain
Maria Carmo Damaso Costa Silva A Carreiras
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/118481/2010

Neuron-glia cross-talk in joint inflammation
Fani Lourença Moreira Neto
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/118522/2010

BDNF-mediated neuronal protection and differentiation in Huntington`s disease
Ana Cristina Carvalho Rego
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/118542/2010

Sirtuins: a novel link between neuroinflammation and neurodegeneration
Maria Teresa Albuquerque Santos Faria Pais
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/118758/2010

Identifying cell-intrinsic axonal regeneration enhancers with translational potential for CNS injury.
Monica M Sousa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/118934/2010

Interaction between endoplasmic reticulum stress-mediated endothelial dysfunction and hippocampal neurogenesis. Potential therapeutic target for the treatment of Alzheimer`s disease
Elisabete Ferreiro
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/119427/2010

The Wnt signalling cascade as a convergence point for Alzheimer`s disease pathology, and a pathway for novel therapeutic intervention
Odete A B da Cruz e Silva
Universidade de Aveiro (UA)

PTDC/SAU-NMC/119640/2010

Endoplasmic reticulum stress preconditioning as a novel approach to mitigate endothelial cell dysfunction and neurodegeneration in Alzheimer`s disease
Cláudia Maria Fragão Pereira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/119672/2010

In vitro model of human neuromuscular junction for the study of Spinal Muscular Atrophy
Evguenia Pavlovna Bekman
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/119732/2010

Impacts of neurogenic and epigenetic modulatory events on the Neurobiology of Depression
Luisa Pinto
Universidade do Minho (UM)

PTDC/SAU-NMC/119840/2010

Signaling pathways of peripheral peptides in the hippocampus: towards novel disease-modifying drugs for Alzheimer`s disease
Cláudia Maria Fragão Pereira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/119843/2010

Anatomical, neurochemical and functional classification of spinal lamina I local-circuit neurons
Peter Szucs
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/119862/2010

Regulation of transthyretin by estradiol in the brain of Alzheimer`s patients and in a mouse model of the disease: implications on cognitive function and amyloid beta deposition
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/SAU-NMC/119928/2010

Protein aggregate formation, dynamics and clearance in neurodegenerative disorders: parkin and PKCgamma mutants as a model
Isabel Alonso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/119958/2010

The new LAP1B/PP1 complex contributes to the underlying molecular mechanisms of Early-Onset Torsion Dystonia
Sandra Maria Tavares da Costa Rebelo
Universidade de Aveiro (UA)

PTDC/SAU-NMC/120041/2010

DTDrugs. Dual-Target-Directed Drugs for Parkinson`s Disease
Fernanda Borges
Associação para o Desenvolvimento da Faculdade de Ciências (ADFCUP/FCUP/UP)

PTDC/SAU-NMC/120277/2010

Role of neuronal afferents as mediators of estrogen-induced structural plasticity in the hypothalamic site that regulates sexual behavior
Maria Dulce Cordeiro Madeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/120315/2010

Mecanisms of regulation of proteasome activity under excitotoxic conditions
Margarida Alexandra Vaz Caldeira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/120330/2010

Influence of nutritional factors in neuronal survival and oxidative stress in the hippocampal formation of the young Rat
José Paulo Alves Vieira de Andrade
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NMC/120360/2010

Modulation of endocanabinoid signalling in the hippocampus by adenosine and caffeine
Joaquim Alexandre Ribeiro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/120376/2010

Modulation of microglial reactivity by GDNF: relevance to dopaminergic protection
Graça Maria Fernandes Baltazar
Universidade da Beira Interior (UBI)

PTDC/SAU-NMC/120439/2010

DJ-1 neuronal rescue under oxidative stress: implications for Parkinson`s disease
BRUNO JOSÉ FERNANDES OLIVEIRA MANADAS
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/120520/2010

Role of the transmembrane AMPA receptor regulatory protein stargazin in homeostatic synaptic plasticity
Ana Luisa Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/120542/2010

UPS, Autophagy and GSTpi: two cellular waste conveyors and one new sweeper.
Maria João Carlos da Silva Gama
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/120553/2010

Effects of the orexigenic peptide ghrelin on glutamatergic synaptic transmission
Sandra Manuela Domingues dos Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/120651/2010

Controlo da interacção neurónio-glia por purinas durante a neuroinflamação
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/120758/2010

Carbon monoxide: novel strategies to regenerate damaged cerebral tissue by stimulating neuronal differentiation and neurogenesis
Helena Luisa de Araujo Vieira
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-NMC/120970/2010

Weight loss in AD: Failure of leptin - ghrelin crosstalk?
Rosa Maria Branco de Matos Costa Resende
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/121418/2010

A New Regulatory Mechanism involving p53 in JMJD3-mediated Neurogenesis
SUSANA ZEFERINO SOLÁ DA CRUZ
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-NMC/121448/2010

Can Parkinson disease be treated with berberine? Role of SIRT1 activation in the improvement of mitochondrial energy deficit
Carlos Palmeira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/121714/2010

Searching for molecular markers of stroke in the cerebrospinal fluid with impact on neurogenesis of choroid plexus epithelial cells
Cecília Reis Alves SANTOS
Universidade da Beira Interior (UBI)

PTDC/SAU-NMC/121874/2010

Caloric restriction delays aging: role of blood brain barriers
Célia Alexandra Ferreira de Oliveira Aveleira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/121962/2010

GABA & glutamate high affinity transport modulation by purines in epilepsy
Joao Miguel da Silva Cordeiro
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-NMC/122019/2010

Do caffeine and adenosine A2A receptor antagonists prevent neurotoxicity and memory dysfunction associated with prion protein misfunction?
PAULA MARIA GARCIA AGOSTINHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/122035/2010

Spine dynamics in neural circuit plasticity and mental retardation
Inbal Israely
Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (FC Champalimaud)

PTDC/SAU-NMC/122108/2010

Characterization of the Retromer as a key multifunctional complex in neuronal signaling
Sandra Isabel Moreira Pinto Vieira
Universidade de Aveiro (UA)

PTDC/SAU-NMC/122160/2010

Inhibition of microglia by neuropeptide Y - neuroprotection in Alzheimer´s disease?
Joao Jose Oliveira Malva
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/122217/2010

Linking striatal-dependent behaviors to specific neuronal populations.
Domingos Manuel Pinto Henrique
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NMC/122377/2010

Retrograde-induced cell death: role of proneurotrophins
Ramiro Almeida
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/122786/2010

Relationship between adenosine A1 receptor and cGMP levels in the hippocampus: implications in neurotransmission and neuroprotection
José Francisco da Silva Cascalheira
Universidade da Beira Interior (UBI)

PTDC/SAU-NSC/116545/2010

Dissecting RhoA contribution to neurodegeneration and repair in brain ischemia
Sofia Santos
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NSC/116694/2010

Frontotemporal Lobar Degeneration and Motor Neuron Disease: where is the border?
Alexandre Valério de Mendonça
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NSC/117028/2010

Osteoarthritis versus diabetic neuropathy: changes in the emotional pain control system and their reversal by antidepressants
Filipa Santos Costa Pinto-Ribeiro
Universidade do Minho (UM)

PTDC/SAU-NSC/117049/2010

The evolution of foraging strategies between closely related species of fruit fly larvae, Drosophila ananassae and Drosophila pallidosa
Christen Mirth
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/117201/2010

Functioning in Bipolar Disorders: A Clinical Guide using the ICF Core Set for BD as a reference
RICARDO DUARTE MIRANDA DE GUSMÃO
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-NSC/117474/2010

Anxiety disorders: the limbic system as a neuroanatomical substrate for lesion and repair
JOSÉ MIGUEL GOMES MOREIRA PÊGO
Universidade do Minho (UM)

PTDC/SAU-NSC/117607/2010

Long latency evoked potencials in the differential diagnosis of cognitive deficits and dementia
Maria da Assunção Morais e Cunha Vaz Patto
Universidade da Beira Interior (UBI)

PTDC/SAU-NSC/117864/2010

Positive affect, emotions and pain perception in chronic pain
Gina Maria Costa Caetano
Universidade de Coimbra (UC)

PTDC/SAU-NSC/118143/2010

Does prenatal education on infant`s sleep prevents sleep problems and parental distress?
Sandra Carvalho Bos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NSC/118416/2010

Synaptic plasticity, cognition and aging: A novel view on old physiological mechanisms
Maria José de Oliveira Diógenes Nogueira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NSC/118527/2010

Effects of stroke on the musculoskeletal system: Contribution to the development of methodologies to support post-stroke diagnosis and rehabilitation
José Aurélio Marques Faria
Universidade da Beira Interior (UBI)

PTDC/SAU-NSC/118568/2010

Clinical and genetic studies on Charcot-Marie-Tooth disease: the first systematic and integrated study to characterize a Portuguese patient cohort
Gabriel Miltenberger-Miltenyi
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NSC/118574/2010

A Doença de Fabry: Novas perspectivas acerca do fenótipo neurológico e lipídico da doença.
Lorena Maria Gomes Rodrigues
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NSC/118600/2010

Automatic Recognition of Animal Behaviour Patterns
Paulo de Castro Aguiar
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/SAU-NSC/119200/2010

Assessment of cognitive ability in the elderly: intervention and empowerment for self-care
João Luís Alves Apóstolo
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-NSC/119220/2010

Development and validation of a web based cognitive training interface - COGWEB
Maria Joana Folha Rodrigues da Costa Pais
Unidade Local de Saúde de Entre Douro e Vouga, EPE (CHEDV)

PTDC/SAU-NSC/119983/2010

Anxiety, Fear and Experience of Pain in 10 to 16 years old Pediatric Dentistry Patients
David José Casimiro de Andrade
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-NSC/119993/2010

Neurobiological association of pain and blood pressure control in the central nervous system
António Albino-Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NSC/120133/2010

Dopaminergic neurotransmission in dietary learning and obesity
Rui Costa
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/120378/2010

Etiology of suicide in Portugal: identifying genetic variants associated with increasing risk of suicide
Alda Maria Abreu Cardoso
Universidade de Coimbra (UC)

PTDC/SAU-NSC/120385/2010

Criminality in Portugal: identifying genetic variants for prevention
Alda Maria Abreu Cardoso
Universidade de Coimbra (UC)

PTDC/SAU-NSC/120425/2010

Structural and Functional Analysis of Vision in Multiple Sclerosis Patients
PEDRO MONTEIRO
Universidade da Beira Interior (UBI)

PTDC/SAU-NSC/120491/2010

EEG gamma activity in patients with Juvenile Myoclonic Epilepsy)
Maria Luiza Constante Rosado
Universidade da Beira Interior (UBI)

PTDC/SAU-NSC/120600/2010

The role of time in associative learning
Marta de Aragão Pacheco Moita
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/120705/2010

Neuronal mechanisms underlying mate preference
Susana Q Lima
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/120706/2010

Neuronal mechanisms underlying sex hormone-dependent switch of sexual receptivity
Susana Q Lima
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/120794/2010

Neurobiological Inheritance of Psychological Trauma
Ivone Luísa de Castro Vale
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NSC/121580/2010

Neural circuit maping of social transmission of fear in rats
Marta de Aragão Pacheco Moita
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/121743/2010

Multidisciplinary, longitudinal neurodevelopment evaluation of children with neurossensorial deafness fitted with cochlear implants
Teresa Margarida Carreira Agostinho Mota Castelo
Centro Hospitalar de Coimbra E.P.E. (CHC)

PTDC/SAU-NSC/121843/2010

Developing high-performance microfabricated devices for recording neural activity
Adam Raymond Kampff
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-NSC/121915/2010

Functional Evaluation of Central Nervous System Autonomic Centers by Functional Magnetic Resonance during Sympathetic and Parasympathetic stimulation
Jose Luis Bliebernicht Ducla Soares
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-NSC/122069/2010

A multi-center, randomized,controlled, rater-blind, 26-weeks trial to evaluate the efficacy of a speech therapy program in patients with the diagnosis of Primary Progressive Aphasia
Manuela Guerreiro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-NSC/122201/2010

Impact of fetal development parameters on neuro-cognitive deficits in congenital heart disease (CHD): comparing subsamples of Cyanotic and Acyanotic Patients
Maria Emília Torres Eckenroth Guimarães Areias
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-NSC/122755/2010

Games improving disorders of attention deficit and hyperactivity
Rui Rijo
Instituto de Engenharia de Sistemas e Computadores de Coimbra (INESC Coimbra)

PTDC/SAU-BMA/118193/2010

REGENERAÇÃO NUM MICROAMBIENTE HOSTIL - EXPANSÃO DE CÉLULAS DO NÚCLEO PULPOSO
Mário Barbosa
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/118394/2010

Conjugados polímero-droga como sistemas de transporte em doenças neurodegenerativas
Isabel dos Santos Cardoso
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BMA/118564/2010

BioBone - Engineering biomaterials with chemical and biological signals for enhanced bone regeneration
Isabel Leonor
Universidade do Minho (UM)

PTDC/SAU-BMA/118793/2010

PART4CEM - Nanostructured inorganic particles and modified polysaccharides for formulation of bioactive glass-ionomer bone cements
Ricardo Alexandre Rodrigues Pires
Universidade do Minho (UM)

PTDC/SAU-BMA/119049/2010

CONTACT - Synthesis, activation and functionalization of materials for contact lens
José Filipe Vilela Vaz
Universidade do Minho (UM)

PTDC/SAU-BMA/119156/2010

Bioresponsive Liquid Crystal Microdroplets
Abid Hussain
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-BMA/119650/2010

OptiSkin - development of delivery solutions for topical treatment of skin
Artur Cavaco-Paulo
Universidade do Minho (UM)

PTDC/SAU-BMA/119962/2010

Digital Impression System for Dental Prosthesis
Jaime Francisco Cruz Fonseca
Universidade do Minho (UM)

PTDC/SAU-BMA/120218/2010

BIOVERA - Aloe vera-based polymeric systems for treatment of acute superficial and full-thickness skin wounds
Simone Silva
Universidade do Minho (UM)

PTDC/SAU-BMA/120350/2010

MenisReg - Meniscus Regeneration using Tissue Engineering Strategies
João Espregueira-Mendes
Universidade do Minho (UM)

PTDC/SAU-BMA/120781/2010

The Highly Focalized Thermotherapy using a nanoparticle ferrimagnetic cement in association with a conditioned medium
Jose Roberto Tinoco Cavalheiro
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/120812/2010

Clinical trial for the evaluation of the MES membrane for bone regeneration
Jose Roberto Tinoco Cavalheiro
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/120817/2010

Development and evaluation of a natural adapted membrane for neural tissue regeneration
Jose Roberto Tinoco Cavalheiro
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/121150/2010

Research and development of a bioactive scaffold to assist the regeneration of injured spinal cord
Célia Maria Reis Henriques
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-BMA/121617/2010

SIMONI-Development of a mechanical knee simulator for ligamentar surgery optimization
Mário Augusto Pires Vaz
INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI/UP)

PTDC/SAU-BMA/121624/2010

In-vitro and in-vivo tests to assess the effects of phytochemical-rich food on the bioaccessibility and bioavailability of fishery products presenting high levels of mercury (HealthPhysh)
Maria leonor Martins Braz de Almeida Nunes
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-BMA/121800/2010

ComforFoam - Nanocomposites of polyurethane foams for the comfort of people with special needs
Fernando Moura Duarte
Universidade do Minho (UM)

PTDC/SAU-BMA/121819/2010

InSituScaf- Natural-origin smart scaffolds with the ability of in situ formation of pores: a novel strategy for bone tissue engineering and regenerative medicine
Ana Margarida Martins de Sousa
Universidade do Minho (UM)

PTDC/SAU-BMA/121879/2010

Giant unilamellar liposomes - development of a new approach to treat acute pulmonary oedema
Ana Cristina Aguiar dos Santos
Universidade de Coimbra (UC)

PTDC/SAU-BMA/121997/2010

Zirconia evaluation as a material to use in Clinical Dentistry
André Correia
INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI/UP)

PTDC/SAU-BMA/122111/2010

Nanomaterials for miRNA delivery- miRNA-Nano
Ricardo Neves Pires das Neves
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/SAU-BMA/122140/2010

CardiScreen - Nanostructured sensors for fast-screening of cardiac biomarkers in point-of-care
Maria Goreti Ferreira Sales
Instituto Superior de Engenharia do Porto (ISEP/IPP)

PTDC/SAU-BMA/122175/2010

MagBone - Development of new multifunctional magnetic nanoparticles for the diagnosis and treatment of osteosarcoma
João Paulo Miranda Ribeiro Borges
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FCTUNL/UNL)

PTDC/SAU-BMA/122242/2010

HypoxiGen - Influence of hypoxic conditions in chondrocytes and stem cells co-cultures for generation of cartilage in vitro
Nuno Neves
Universidade do Minho (UM)

PTDC/SAU-BMA/122444/2010

A molecular view of dental restoration
Francisco Jorge Fernandes Caldeira
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-BMA/122459/2010

WOUNDRESS - Chitosan/soy-based membranes - a new approach in wound dressing.
Maria Carlota Saldanha Lopes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BMA/122549/2010

Tissue healing of immediate implant placement into fresh extraction sockets with titanium versus zirconium oxide implants: an experimental study in the beagle dog
João Manuel Mendez Caramês
Faculdade de Medicina Dentária da Universidade de Lisboa (FMD/ULisboa)

PTDC/SAU-BMA/123154/2010

Sinus lift side window technique: autologous bone vs. substitute bone. A randomized clinical trial with histological and radiological evaluation.
António Cabral de Campos Felino
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-ENB/116662/2010

Computer-Aided Diagnosis Methods based Weighted Ensemble Classification in Breast Cancer Imaging.
Miguel Angel Guevara López
INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial (INEGI/UP)

PTDC/SAU-ENB/116815/2010

Integrating novel biomaterials with stem cell differentiation toward orthopaedic interventions
Maria Paula Polónia Gonçalves
Universidade de Aveiro (UA)

PTDC/SAU-ENB/116883/2010

A new multimodal imaging approach for breast cancer: PEM-UWB
RAQUEL CRUZ DA CONCEIÇÃO
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ENB/116993/2010

RTmon - real-time imaging device for improving photon and particle external radiotherapy: from viability to proof of clinical usability
Paulo Alexandre Vieira Crespo
Laboratório de Instrumentação e Física Experimental de Partículas (LIP)

PTDC/SAU-ENB/116997/2010

Portuguese PET technology for in vivo tumor modelling in small animals
Pedro MIguel Dinis de Almeida
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ENB/117013/2010

AMYLOIDETECTORS: Employing amyloid fibrils as biosensors of the interaction of peptides with phospholipids and/or protein domains.
IVO CRISTIANO DA ROCHA MARTINS
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ENB/117087/2010

Development of dynamic systems models for body composition evaluation
Maria Teresa Braga Valente de Almeida Restivo
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ENB/117123/2010

Speech Production and Perception in Hearing Impaired Children
Luís Miguel Teixeira de Jesus
Universidade de Aveiro (UA)

PTDC/SAU-ENB/117387/2010

i3DPuncture System - Robotic system based on motion tracking sensors to automatically perform the puncture in the percutaneous nephrolithotomy
João Luís Araújo Martins Vilaça
Universidade do Minho (UM)

PTDC/SAU-ENB/117415/2010

Female fecal incontinence, a biomechanical study
Marco Paulo Lages Parente
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ENB/117560/2010

Fiber Optic NIR Imaging and Diagnostic on Dentistry (NIRDENT)
António Lobo Ribeiro
Fundação Ensino e Cultura Fernando Pessoa (FECFP)

PTDC/SAU-ENB/117720/2010

Magnetic resonance non-invasive quantitative evaluation of cerebrovascular reactivity and cerebral oxygen metabolism changes in healthy subjects and small vessel disease patients.
Patrícia Figueiredo
Associação do Instituto Superior Técnico para a Investigação e o Desenvolvimento (IST-ID)

PTDC/SAU-ENB/117740/2010

ALLOCORD-Study of the non-immunogenic potential of umbilical cord derived stem cells for Regenerative Medicine applications
Ana Rita da Costa Pinto
Universidade do Minho (UM)

PTDC/SAU-ENB/117817/2010

Nanostructural and mechanical characterization of the mineralized collagen matrix of osteoporotic bone in a mouse model using AFM
Saba Abdulghani
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ENB/118034/2010

Desenvolvimento de particulas inspiradas em mecanismos biológicos para promover a expansão de células estaminais hematopoiéticas do sangue do cordão umbilical
Raquel Madeira Gonçalves
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-ENB/118044/2010

Simulation and control of emergent oscillatory phenomena in biological systems
Rui Manuel Agostinho Dilao
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-ENB/118181/2010

Development of nano-bioelectromagnetic wound dressings for the therapeutic of pressure ulcers
Nuno José Ramos Belino
Universidade da Beira Interior (UBI)

PTDC/SAU-ENB/118601/2010

Improvement of the diagnostic value of Digital Breast Tomosynthesis using statistical image reconstruction algorithms
Pedro MIguel Dinis de Almeida
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ENB/118687/2010

Influência da resposta biomecânica da córnea à terapia e cirurgia refractiva nas suas propriedades ópticas e na qualidade da visão.
Sandra Maria de Braga Franco
Universidade do Minho (UM)

PTDC/SAU-ENB/118853/2010

FIRST - From Inflammation to the Regeneration of Skin Tissue Valorization of inflammatory signals to improve the performance of skin tissue engineering constructs
Tírcia Susete Xavier Carlos Santos
Universidade do Minho (UM)

PTDC/SAU-ENB/118928/2010

Assessment of the correlation between retinal and carotid circulation using automatic image analysis
AURÉLIO JOAQUIM DE CASTRO CAMPILHO
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-ENB/119060/2010

ErgoSuit - Validation of measures and identification of parameters for the study of comfort and cognitive neuroergonomics
Miguel Ângelo Fernandes Carvalho
Universidade do Minho (UM)

PTDC/SAU-ENB/119074/2010

Concentrated photoactivation: focusing light through scattering
João Miguel Pinto Coelho
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ENB/119123/2010

vASCskin - Microengineered hydrogels for improving the vascularization of dermal substitutes
Vitor Manuel Correlo da Silva
Universidade do Minho (UM)

PTDC/SAU-ENB/119247/2010

Development of novel lentiviral vectors for multiple miRNA expression: Towards new RNAi-based therapeutics for Alzheimer`s disease
Ana Luísa Colaço Cardoso
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ENB/119406/2010

Engineering the System of Critical Care to Improve Patient Outcomes
JOÃO MIGUEL DA COSTA SOUSA
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ENB/119409/2010

Extraction of quantitative features from mammary lesions in elastography images
Ana Isabel Pereira Martins Leiria
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/119456/2010

Development of an intelligent system for the objective assessement of sleep movements in demented patients
Nuno José Ramos Belino
Universidade da Beira Interior (UBI)

PTDC/SAU-ENB/119523/2010

Optimization of coloured lenses for daltonics
Sérgio Miguel Cardoso Nascimento
Universidade do Minho (UM)

PTDC/SAU-ENB/119811/2010

A New Integrated Hybrid Biosignal Dry Electrode with Drug Delivery Capabilities (IHE)
João Paulo Cunha
Universidade de Aveiro (UA)

PTDC/SAU-ENB/119814/2010

Displacement-frequency transform applied to Doppler Ultrasound blood flow signals
Ana Isabel Pereira Martins Leiria
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/119996/2010

TheraPerio - Development of an autologous tissue engineering therapy for periodontal regeneration
Maria Manuela Estima Gomes
Universidade do Minho (UM)

PTDC/SAU-ENB/120100/2010

Nano inflammation: How inflammation early affects bone properties at the onset of rheumatoid arthritis.
João Eurico Cortez Cabral da Fonseca
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ENB/120135/2010

WounDEX: A novel beta-cyclodextrin/Dextrin-based hydrogel for efficient wound healing
João Pedro Martins Soares de Castro e Silva
Universidade do Minho (UM)

PTDC/SAU-ENB/120258/2010

PolyEndo- Polymicrobial competition in endocarditis
Cláudia Sousa
Universidade do Minho (UM)

PTDC/SAU-ENB/120477/2010

CTGNET - Cardiotocogram Classification and Predition using Neural Networks
Jorge Manuel Fernandes dos Santos
Instituto Superior de Engenharia do Porto (ISEP/IPP)

PTDC/SAU-ENB/120524/2010

Noninvasive Ischemia Detection from Color Fundus Photography
Pedro Miguel Picado de Carvalho Serranho
Associação para a Investigação Biomédica e Inovação em Luz e Imagem (AIBILI)

PTDC/SAU-ENB/120675/2010

Bioartificial liver for clinical support in acute liver failure - an international and multi hospital and biotechnology approach
Paulo Alexandre do Rosário Marcelino
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ENB/120718/2010

Comprehensive multi-parametric analysis of the limbic system connectivity in post-traumatic epilepsy patients
HUGO ALEXANDRE TEIXEIRA DUARTE FERREIRA
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ENB/120807/2010

Characterization of temperature propagation on artificial biological tissues under ultrasonic effects using neuro-fuzzy models.
Maria da Graça Cristo dos Santos Lopes Ruano
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/120851/2010

Targeted cancer therapy using Dll4-Fc-releasing nanoparticles
Ana Teresa Fernandes Nunes Tavares
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-ENB/120859/2010

A functional connectivity study of the origin and dynamics of rest brain networks.
Alexandre da Rocha Freire de Andrade
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ENB/121046/2010

Compact Tunable Vibration Absorber for Tremor Suppression
Luis Alexandre Machado da Rocha
Universidade do Minho (UM)

PTDC/SAU-ENB/121055/2010

SimOzone - Numerical Simulation of the Non-Invasive Ozone-Therapy Process for the Treatment and Rehabilitation of the Intervertebral Disc Diseases
José Luis de Carvalho Martins Alves
Universidade do Minho (UM)

PTDC/SAU-ENB/121095/2010

Estudo do papel do novo factor de crescimento Ccbe1 na criação de tecido cardíaco apartir de células ES
José António Henriques de Conde Belo
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ENB/121099/2010

Development of a Fluorescence Lifetime Ophthalmoscope
Pedro Manuel Cardoso Vieira
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-ENB/121234/2010

SeCol - Automatic Detection and Segmentation of Cortical Lesions in Multiple Sclerosis
Carlos Manuel Gregorio Santos Lima
Universidade do Minho (UM)

PTDC/SAU-ENB/121393/2010

Intelligent Support System for CVA Diagnosis by Cerebral Computerized Tomography
Antonio Ruano
Universidade do Algarve (UAlg)

PTDC/SAU-ENB/121442/2010

DIFFUSE - Multifunctional Nanostructured Systems for the Local Delivery of Bioactive Agents to Drive Mesenchymal Stem Cells Differentiation
Albino Martins
Universidade do Minho (UM)

PTDC/SAU-ENB/121471/2010

Injectable calcium phosphate-PVA Biomaterials associated to mesenchymal stem cells for bone tissue engineering
NANDYALA SOORAJ HUSSAIN
Instituto de Engenharia de Sistemas e Computadores do Porto (INESC Porto/FE/UP)

PTDC/SAU-ENB/121490/2010

SN4SP: Sensor network for special people
Paulo Jorge Carvalho Menezes
Instituto de Sistemas e Robótica (ISR)

PTDC/SAU-ENB/121550/2010

Métodos para diagnóstico assistido por computador de detecção de lesões pulmonares em imagens PET/CT
Susana Evaristo de Oliveira Branco
Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (FC Champalimaud)

PTDC/SAU-ENB/121745/2010

Evaluation of the type of connection in dental bridges
Maria Augusta Neto
Universidade de Coimbra (UC)

PTDC/SAU-ENB/121777/2010

Optimization of carotid surgery design towards application at hospital
Carlos Alberto Conceição António
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ENB/121786/2010

Optimization of external fixators configuration in the treatment of bone fractures
CARLOS ALEXANDRE BENTO CAPELA
Instituto Politécnico de Leiria (IPLeiria)

PTDC/SAU-ENB/121861/2010

OMNI ROD - Pervasive Health Care for Wheelchair Users
Octavian Adrian Postolache
Instituto de Telecomunicações (IT)

PTDC/SAU-ENB/121976/2010

StemSource - Converting Stem Cell Potential into Clinical Applications: Systematic Study of Different Cell Sources
Rui Sousa
Universidade do Minho (UM)

PTDC/SAU-ENB/122014/2010

IndPCell- Efficient osteoblasts and cardiomyocytes differentiation of iPS cells using non-viral vectors: a new strategy for regenerative medicine
Rui L Reis
Universidade do Minho (UM)

PTDC/SAU-ENB/122144/2010

Optimization of cadaveric embalming via dedicated vascular perfusor development
JOAO ERSE DE GOYRI O´NEILL
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ENB/122237/2010

Kidney critical doses during metabolic radiotherapy with beta emitters labeled peptides
João António Miranda dos Santos
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ENB/122267/2010

Using the fundamentals of phase transitions to tackle the problem of amyloid formation
Fernando Alberto Nogueira da Rocha
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-ENB/122321/2010

Effective Screening and Aided Diagnosis of Eye Pathologies using Image Analysis
António Manuel Gonçalves Pinheiro
Universidade da Beira Interior (UBI)

PTDC/SAU-ENB/122363/2010

Molecular imaging and radiobiological modelling in External Radiotherapy
Anabela Gregório Dias
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ENB/122396/2010

Active Perception and Attention Guidance to Promote Social Interaction
Jorge Manuel Miranda Dias
Instituto de Sistemas e Robótica (ISR)

PTDC/SAU-ENB/122410/2010

Labeling of human endothelial progenitor cells for detection by magnetic resonance imaging
Maria Constança Campos Morgado Silva Pinto Baptista Coelho
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ENB/122550/2010

Study of gender differences on aging in human brain´s structural and functional connectivity assessed using MRI: applications in both normals and on patients with neurodegenerative disorders
Nicolas Francisco Lori
Universidade de Coimbra (UC)

PTDC/SAU-ENB/122581/2010

Development of a dose assessment methodology comprising image, Monte Carlo-based calculus and biokinetic models information in patients undergoing ordinarily prescribed Molecular Imaging examinations
Luis Manuel Carvalho Freire
Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (FC Champalimaud)

PTDC/SAU-ENB/122669/2010

MATERNUS. Computerized analysis of simultaneous recordings of maternal and fetal heart rates. Development and evaluation of a maternal-fetal monitoring tool.
Hernâni Manuel da Silva Lobo Maia Gonçalves
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ENB/123012/2010

Assessment of bone fracture risk in pre and postmenopausal women of North of Portugal
Elza Maria Morais Fonseca
Instituto Politécnico de Bragança (IPBragança)

PTDC/SAU-ENB/123042/2010

HEMES: Human Energy for Medical Equipment Supply
Stanimir Stoyanov Valtchev
Instituto de Desenvolvimento de Novas Tecnologias (UNINOVA)

PTDC/SAU-ENB/123047/2010

Study of bruxism based on a multiscale approach
Renato Manuel Natal Jorge
Instituto de Engenharia Mecânica (IDMEC)

PTDC/SAU-ENB/123052/2010

Surface electromyography using electrodes embedded on textile substrates
André Paulo de Almeida Whiteman Catarino
Universidade do Minho (UM)

PTDC/SAU-EPI/116654/2010

Insulin Clearance, the forgotten: an underlying trait in diabetogenesis
Maria Paula Borges de Lemos Macedo
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-EPI/116761/2010

National Registry and Epidemiologic Study of Inherited Epidermolysis Bullosa
Carla Sa-Couto
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-EPI/117214/2010

Sudden death investigation in young adults: from forensic autopsy diagnosis to prevention.
Agostinho Santos
Instituto Nacional de Medicina Legal e Ciências Forense, I.P. (INMLCF/MJ)

PTDC/SAU-EPI/117501/2010

Genetic susceptibility to Influenza infection
Marta Barreto
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-EPI/118015/2010

Predictors of biological drugs toxicity/adverse events in the treatment of immune-mediated rheumatic diseases: applying pharmacogenomics to personalize Medicine
Helena Canhão
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-EPI/118066/2010

Child death investigation. Proposal of a multidisciplinary protocol.
Agostinho Santos
Instituto Nacional de Medicina Legal e Ciências Forense, I.P. (INMLCF/MJ)

PTDC/SAU-EPI/118204/2010

Malaria antibody profiling in Angola and Principe: finding biomarkers of immunity decay and disease severity.
CARLOS AUGUSTO GOMES BARBOSA DA PENHA GONÇALVES
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-EPI/118659/2010

Assessment of the cognitive and functional ability in older people for medication management
Maria Sofia Rodrigues Pintado De Oliveira Martins
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-EPI/118918/2010

Detecting and predicting the evolution of transmission of HIV-1 drug resistance combining a phylogenetic and mathematical modelling approach
Ana Barroso Abecasis
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-EPI/118973/2010

Sexual Dysfunction and Cardiovascular Disease: Cardiovascular risk among patients seeking help for sexual dysfunctions
Alberto Adriano Archer Galvão Teles
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-EPI/119012/2010

O papel dos elementos genéticos móveis na selecção e persistência de linhagens clonais de Escherichia coli disseminados globalmente
Ângela Patrícia Silva Novais
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-EPI/119264/2010

Multifactorial approach of subclinic atherothrombosis in the diabetic patient
Luis Filipe Vilela Pereira Macedo
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-EPI/119294/2010

Epidemiology and aetiology of age related hearing impairment
Maria Helena Caria
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-EPI/119457/2010

MRSA clones that can cross the boundaries between hospital and community: search for determinants of epidemic success
Hermínia de Lencastre
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-EPI/119821/2010

eLink - Linking Data for Molecular Epidemiology and Microbial Typing using the Semantic Web
João André Nogueira Custódio Carriço
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-EPI/119989/2010

Cystic Fibrosis: Study of prevalence and analysis of CFTR gene mutations in Portuguese population
Ana Isabel Fernandes Grangeia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-EPI/120108/2010

Rehabilitation and quality of life in residential facilities for people with long-term mental illness: a multicentre, cluster randomized controlled trial
Graça Maria Pereira Cardoso
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-EPI/120185/2010

NutriOSTEO - Dietary habits, hyperhomocysteinemia and protective factors in osteoporosis: Nutritional Study
Maria Helena Rodrigues Gonçalves Soares Costa
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-EPI/120345/2010

The role of child care institutions and child care homes in human cytomegalovirus congenital infection
Paulo Jorge Pereira Cruz Paixão
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-EPI/120444/2010

Evaluation of Spatio-Temporal Models of Portuguese Cancer Mortality Patterns
Bruno de Sousa
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-EPI/120877/2010

Hepatic steatosis in Portugal - Prevalence in the general population and risk factors. Importance of bacterial proliferation
Helena Cortez-Pinto
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-EPI/121064/2010

Study of the Impact of Imunossupressive Therapy in Kidney Transplant Recipients
Carla Maria Teixeira de Barros Branco Ló
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-EPI/121087/2010

IMeGui - Interpretable Medical Guidelines
Paulo Novais
Universidade do Minho (UM)

PTDC/SAU-EPI/121170/2010

Population genetics and vector competence of Aedes aegypti: implications for dengue epidemiology
Patrícia Isabel Rosa Salgueiro
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-EPI/121172/2010

Searching for genomic markers associated with increased epidemicity and pathogenic potential in high-level gentamicin and glycopeptides resistant nosocomial enterococci.
Rosario Mato Labajos
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-EPI/121405/2010

Psychosocial dimensions of precarious employment, health and individual narratives
Paula Joana Pinto Custodio da Silva Oliveira
Faculdade de Psicologia e de Ciências da Educação da Universidade do Porto (FPCE/UP)

PTDC/SAU-EPI/121666/2010

Complexity and Disagreement in Health Sciences
Cristina Maria Nogueira da Costa Santos
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-EPI/121930/2010

Effects of the global economic crisis on mental health of the populations - Study on the prevalence of mental disorders, associated risk factors, disability and use of services, in the Portuguese adult population in 2009-2012.
José Miguel Barros Caldas de Almeida
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-EPI/121956/2010

MetS-Teen: Study of Prevalence of Metabolic Syndrome in Adolescents of Oeiras
Paula Vaz Fernandes
Instituto Superior de Ciências Sociais e Políticas (ISCSP/Ulisboa)

PTDC/SAU-EPI/122060/2010

The Eurasian otter as reservoir and vehicle for bacterial virulence factors
Manuela Oliveira
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-EPI/122107/2010

Maputo Project: Population and disease genetics in Mozambique
Ana Sofia Simões Domingues de Almeida Oliveira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-EPI/122372/2010

Transcultural study on postnatal depression: Comparison of populations from urban and rural areas of Angola and Portugal
Maria Emília Torres Eckenroth Guimarães Areias
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-EPI/122376/2010

Prospective Study to determine the cardiovascular risk of the population of Guimarães/Vizela, including the prevalence of Arterial Stiffness and Early Vascular Aging Syndrome
Jorge de Almeida Berkeley Cotter
Universidade do Minho (UM)

PTDC/SAU-EPI/122400/2010

Molecular epidemiology, drug resistance and pathogenesis of HIV and TB in Angola: the Angolan PErinatal HIV Cohort (APEHC)
Nuno Eduardo Moura dos Santos da Costa Taveira
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-EPI/122464/2010

Changing pneumococcal population and diagnostic practices as a consequence of mounting pressure of conjugate vaccines
Jose Melo Cristino
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-EPI/122667/2010

Molecular epidemiology and mechanisms of azole drug resistance in Aspergillus species.
Joao Pedro Silva Frade
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-EPI/122688/2010

Determinants of obstetric surveillance in portuguese and immigrants women
Cláudia Margarida Correia Balula Chaves
Instituto Politécnico de Viseu (IPV)

PTDC/SAU-EPI/122762/2010

Prevalence and determinants of patient adherence to ART and regimen modification, in a portuguese cohort of HIV-infected adults: the ATAR-VIH study
Vasco António de Jesus Maria
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-EPI/122851/2010

Families that care for dependents on self-care - a population-based study in Northern Portugal
Cândida Assunção Santos Pinto
Escola Superior de Enfermagem do Porto (ESEP)

PTDC/SAU-EPI/122867/2010

Surveillance of the emergent Candida parapsilosis antifungal resistance.
Isabel M Miranda
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-SAP/116532/2010

Urban nanoaerosols from a public health perspective (URBSOL)
Teresa Alexandra Peixoto Rocha Santos
Instituto Piaget, Cooperativa para o Desenvolvimento Humano, Integral e Ecológico CRL (IPiaget)

PTDC/SAU-SAP/116591/2010

NANO-Cycle: Effect of the life cycle of nanobased materials in Health & Environment
Ana Paula Piedade
Universidade de Coimbra (UC)

PTDC/SAU-SAP/116950/2010

ControlTB - Pulmonary Tuberculosis Control in Portugal in a space-time perspective: determinants, incidence trends and forecasts in geographic units. A contribution for an optimized Program.
Carla do Rosário Delgado Nunes de Serpa
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/116976/2010

Environment, health practices and microbiological evaluation associated with the handling of urethral and peripheral intravenous catheters
João Manuel Garcia do Nascimento Graveto
Escola Superior de Enfermagem de Coimbra (ESEnfC)

PTDC/SAU-SAP/117037/2010

TransOb - Does pesticide exposure have a transgenerational effect upon obesity epidemic?
Maria Conceicao Costa Pinho Calhau
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-SAP/117045/2010

Effect of environmental factors on DNA-analysis from teeth: developing a protocol
Inês Alexandra Costa de Morais Caldas Paiva
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-SAP/117080/2010

Adaptomics of zoonotic Campylobacter jejuni to environmental challenges.
Patrick de Oliveira Freire
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-SAP/117343/2010

Development of an In Vitro predictability model to identify respiratory allergens
Maria Teresa Cruz
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-SAP/117413/2010

Biopsychosocial determinants with impact in workers mental health and productivity - Recommendations to address health inequalities
José Manuel Domingos Pereira Miguel
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-SAP/117461/2010

Developing competencies of self-regulation on risk behaviors in adolescence
Manuela Ferreira
Instituto Politécnico de Viseu (IPV)

PTDC/SAU-SAP/117519/2010

Health Promotion in Higher education: from conception to assessment of a intervention program for sustainable health
Maria da Piedade Moreira Brandão
Universidade de Aveiro (UA)

PTDC/SAU-SAP/117609/2010

Screen4FoodSafety - Development of Analytical Decision Makers Derived from Mass Spectrometry Detectors as Cost-effective Strategy to Screen PCBs (and Dioxins) in Food-stuffs
José Manuel Florêncio Nogueira
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-SAP/117651/2010

Biomarkers of arsenic exposure on dairy cows
Alvaro Lopes
COFAC, Cooperativa de Formação e Animação Cultural, CRL (COFAC)

PTDC/SAU-SAP/117714/2010

Lead exposure and osteoporosis
José Américo Almeida de Brito
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-SAP/117802/2010

Computer Users´ e-Postural Control (CUePC)
Maria Cristina Damas Argel de Melo
Instituto Politécnico do Porto (IPP)

PTDC/SAU-SAP/118609/2010

GreenToHealth - Urban Green Structure and elderly wellbeing and health
Henrique Jose Nunes Andrade
Instituto de Geografia e Ordenamento do Território da Universidade de Lisboa (IGOT/Ulisboa/ULisboa)

PTDC/SAU-SAP/118623/2010

ControlSmoke - A social marketing program for smoking cessation among female university students
Joaquim Reis
Associação para a Investigação em Design, Marketing e Comunicação (EUROPEIA ID)

PTDC/SAU-SAP/118715/2010

Alert system prototype for the pollution effects on public health applied to the Lisbon area
AMÍLCAR DE OLIVEIRA SOARES
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-SAP/118813/2010

Prevalence and characterization of Staphylococcus aureus in Portuguese-speaking African countries and in East Timor
Marta Aires de Sousa
Cruz Vermelha Portuguesa (CVP)

PTDC/SAU-SAP/118838/2010

EMERGENCY - Safety of emergency surgical care
Olga Machado de Sousa Carneiro
Universidade do Minho (UM)

PTDC/SAU-SAP/118946/2010

Translational research: from the molecular diagnosis to the families. Family implications of predictive testing on portuguese families affected by late-onset neurological diseases.
Milena Paneque
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-SAP/119115/2010

The Portuguese adverse events study: incidence, nature, preventability and impact among hospital patients in Portugal
Antonio Neves Pires de Sousa Uva
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/119161/2010

Identifying the early signs of Autism Spectrum Disorder - integration of behavioral and genetic information for early autism detection in an at-risk population
Astrid Vicente
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-SAP/119199/2010

New arboviruses isolated in Portugal. Risk assessment and public health application.
Maria João Pereira Figueira Alves
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-SAP/119365/2010

Towards antifungal therapies exploring wild plants from Northeastern Portugal: the pathway from extracts to isolated compounds
Mariana Contente Rangel Henriques
Universidade do Minho (UM)

PTDC/SAU-SAP/119442/2010

Analysis of the Impact of the New Public Management Reforms in the Portuguese Public Hospitals
Maria João Major
ISCTE - Instituto Universitário de Lisboa (ISCTE-IUL)

PTDC/SAU-SAP/119449/2010

CLIMATICKDIS - Climate change and ixodid ticks in Portugal: emerging and re-emerging diseases.
Maria Luísa Jorge Vieira
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/119469/2010

Contribution of parasitic diarrheas to the global burden of diarrheal diseases in children under five in rural and urban Mozambique
Sónia Chavarria Alves Ferreira Centeno Lima
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/119544/2010

Predictors of Prosthesis Adjustment and Quality of Life in Lower Limb Amputees and Burden in their Caregivers
Maria Da Graca Pereira Alves
Universidade do Minho (UM)

PTDC/SAU-SAP/119557/2010

CLAMS - Choosing between two clams: public health concerns
Etelvina Figueira
Universidade de Aveiro (UA)

PTDC/SAU-SAP/119662/2010

Nurses´ Attitudes, Conceptualization and Practice when Caring for Families in Primary Health Care
Maria do Céu Aguiar Barbieri de Figueiredo
Escola Superior de Enfermagem do Porto (ESEP)

PTDC/SAU-SAP/119664/2010

UVB and skin cancer: lycopene potential on preventing nonmelanoma skin cancer
Sandra Simões
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-SAP/119767/2010

Study of the morphological and molecular alterations provoked by low frequency noise on the heart of the Wistar rat
José António Mesquita Martins dos Santos
Egas Moniz - Cooperativa de Ensino Superior, CRL (CESEM)

PTDC/SAU-SAP/119908/2010

Screening instrument of psychological distress in oncologic patients
Anabela Maria Sousa Pereira
Universidade de Aveiro (UA)

PTDC/SAU-SAP/120057/2010

Postmortem interval: the contribution of forensic entomology and anthropology
Eugenia Maria Guedes Pinto Antunes Cunha
CENCIFOR - Associação Centro de Ciências Forenses (CENCIFOR)

PTDC/SAU-SAP/120139/2010

Environmental pollution by endocrine disruptors. An integrated risk analysis approach.
Valentina Maria Fernandes Domingues
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-SAP/120179/2010

Aging and Frailty: Prevention and Care
JOSE IGNACIO GUINALDO MARTIN
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-SAP/120340/2010

Occurrence of cyanobacteria and microcistins in São Domingos Reservoir: monitoring, environmental factors related with cyanobacterial growth and impact on public health.
Elsa Maria Alves Dias
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-SAP/120738/2010

Assessing equity in waiting times for elective surgery: an empirical approach
Julian Alejandro Perelman
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/120833/2010

Intervention Program for the Promotion of Autonomy: Quality of life and satisfaction with life in people with Multiple Sclerosis
LUÍSA MARIA DOS REIS PEDRO
ISPA, CRL (ISPA)

PTDC/SAU-SAP/120835/2010

ProAGE - Determinants of health in institutionalized elderly: a longitudinal study in North of Portugal
Elisabete Cristina Bastos Pinto
Universidade Católica Portuguesa (UCP)

PTDC/SAU-SAP/120933/2010

Basic and clinical follow-up approach to sepsis patients
Maria Carlota Saldanha Lopes
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-SAP/120989/2010

EFFECTS OF RAPID MAXILLARY EXPANSION IN CHILDREN WITH TRISOMY 21
David José Casimiro de Andrade
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-SAP/121212/2010

Move2Improve: Movement Evaluation and Training Tool to Improve Living
Verónica Orvalho
Instituto de Telecomunicações (IT)

PTDC/SAU-SAP/121260/2010

Assessment of Oral Health and the Effect of its Improvement on the Quality of Life in a Pediatric Population with Cerebral Palsy
David José Casimiro de Andrade
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-SAP/121329/2010

Predictors of HIV risk behaviour, patterns of HIV testing, and prevalence of HIV among men in Portugal
Henrique Pereira
ISPA, CRL (ISPA)

PTDC/SAU-SAP/121492/2010

Age estimation in a Portuguese population: how nutrition, health factors and social economic status affect different techniques of age estimation.
Maria de Lurdes Ferreira Lobo Pereira
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-SAP/121545/2010

Study of genetic variability within portuguese populations of Ixodes ricinus Linnaeus, 1758 an important european vector for tick-borne diseases
Maria Margarida Santos Silva Serejo
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-SAP/121574/2010

Citizens support website: a contribution to the clients empowerment in health
Paulino Artur Ferreira Sousa
Escola Superior de Enfermagem do Porto (ESEP)

PTDC/SAU-SAP/121604/2010

Microbial risk factors for consumer from live bivalve molluscs production areas (BIVRISK)
Sónia Cristina Nunes Salvador Correia Pedro
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-SAP/121657/2010

Irradiation and atherosclerosic disease - epidemiologic and biologic evaluation of a cohort irradiated in childhood for tinea capitis treatment
Maria Paula Marques Boaventura
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-SAP/121684/2010

Thermal Environment - Scale-up of Laboratory Results for Occupational Context
João Manuel Abreu dos Santos Baptista
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-SAP/121709/2010

The risk of harmful herb-drug interactions between herbal weight loss products and cardiovascular drugs of narrow therapeutic range
Gilberto Lourenço Alves
Universidade da Beira Interior (UBI)

PTDC/SAU-SAP/121768/2010

Development of Integrated Systems Engineering Approaches for Process Improvement in Healthcare Units
Marco Paulo Seabra dos Reis
PRODEQ - Associação para o Desenvolvimento da Engenharia Química (PRODEQ)

PTDC/SAU-SAP/121821/2010

FABYA - Food Allergy, bronchial hyperresponsiveness and asthma in childhood
NUNO MANUEL BARREIROS NEUPARTH
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-SAP/121829/2010

RehabNet: A social network for the deployment and evaluation of online rehabilitation content
Sergi Bermúdez i Badia
MITI - Madeira Interactive Technologies Institute - Associação (Madeira-ITI)

PTDC/SAU-SAP/121853/2010

Environmental Exposure and Health Impacts of Water Disinfection By-products present in Indoor Swimming Pools
Ana Sofia Vilhena Fernandes Pereira Cardoso
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-SAP/121917/2010

Quality of life evaluation in patients treated with dental prosthesis
André Correia
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-SAP/121922/2010

Periodontal Disease and Systemic Patologies: A platform for public health promotion
Ricardo Manuel Casaleiro Lobo de Faria e Almeida
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-SAP/121966/2010

Insomnia in portuguese adolescents. Frequency and repercussions in local health strategies.
Carlos Manuel de Figueiredo Pereira
Instituto Politécnico de Viseu (IPV)

PTDC/SAU-SAP/122037/2010

Multivariate Disease Modelling and Mapping of Public Health Data
Giovani Loiola da Silva
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-SAP/122182/2010

RISK, HEALTH AND WELFARE STATE: COMPLEMENTARY AND ALTERNATIVE MEDICINE AS A RISING POLICY HEALTHCARE ISSUE
Jaime Raúl Seixas Fonseca
Instituto Superior de Ciências Sociais e Políticas (ISCSP/Ulisboa)

PTDC/SAU-SAP/122289/2010

dB@NICU - Strategy effectiveness in monitoring and controlling noise levels in Neonatal Intensive Care Units
Helena da Conceição Borges Pereira Catarino
Instituto Politécnico de Leiria (IPLeiria)

PTDC/SAU-SAP/122630/2010

IExist- Interactive Wearable Assistance System for the Elderly
João Luis Marques Pereira Monteiro
Universidade do Minho (UM)

PTDC/SAU-SAP/122656/2010

Molecular analysis of Toxoplasma gondii strains isolated from humans and animals
Jaime Nina
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-SAP/122693/2010

PrimeCareNet - Primary-Care Networks Dynamics: Clinical Governance diffusion Networking Dynamics and the use of eHealth technologies in Primary Care
Luís Miguel Velez Lapão
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-SAP/122980/2010

IndiQ - Quality and performance indicators in health information systems: using secondary data to assess hospital performance
JOSÉ ALBERTO DA SILVA FREITAS
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-SAP/123070/2010

Bringing safety to hospital facilities: is hydrogen peroxide vapor a useful strategy for fighting against healthcare-related infections?
Acácio Gonçalves Rodrigues
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-SAP/123107/2010

STENOCROSSTALK: Antimicrobial susceptibility and virulence crosstalk in Stenotrophomonas maltophilia-Assessement of environmental modulation on genetic traits
RICARDO PEDRO MOREIRA DIAS
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-SAP/123109/2010

Analysis of hereditary cardiovascular risk factors - a family based approach to prevent premature cardiovascular events
Mafalda Bourbon
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-SAP/123118/2010

Temperature screening for triage and critical patient`s evaluation using medical thermal imaging
Ricardo Ângelo Rosa Vardasca
Instituto Politécnico de Leiria (IPLeiria)

PTDC/SAU-SAP/123121/2010

GLOVEAID - Instrumented textile glove for complemental rehabilitation of muscular injuries using embedded shape memory alloys
André Paulo de Almeida Whiteman Catarino
Universidade do Minho (UM)

PTDC/SAU-TOX/116511/2010

Modifying Machado-Joseph disease progression by blockage of Adenosine A2A receptors
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/116539/2010

Combinations of cocaine and heroin- Mechanisms of speedball action
MARIA TERESA MARTINS DA CUNHA OLIVEIRA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/116627/2010

TARGETING HEME PHARMACOLOGICALLY TO TREAT SEVERE FORMS OF MALARIA
Miguel Amado Franco Parreira Soares
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-TOX/117121/2010

Caveolae involvement in the mechanism of neurotoxicity of aluminium
Virgília Sofia Almeida de Azevedo e Silva
Universidade de Aveiro (UA)

PTDC/SAU-TOX/117247/2010

Aldosterone and its receptors: new targets for the prevention of neuronal death in diabetic retinopathy
Paulo Fernando Martins dos Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/117267/2010

Neuro-DynaMito: Epigenetic modulation of neuronal mitochondrial dynamics and survival
Jorge Miguel de Ascenção Oliveira
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/117322/2010

Silencing of Kupffer cell inflammatory activity as a novel therapeutic strategy for the treatment of glucose intolerance and Type 2 diabetes
Teresa de Jesus Cardoso Delgado
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-TOX/117499/2010

Cardiac Mitochondrial Dysfunction During Hyperglycaemia - Role of Oxidative Stress, Mitochondrial Permeability Transition Induction and Prevention by Carvedilol
Maria Sancha de Jesus Vieira dos Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/117669/2010

Increased intraocular pressure and neuroagression modulation through type-1 receptor cannabinoid agonism (O-2545)or antagonism (O-2050) in a Wistar rat ´´glaucoma-like´´ model
Luis Almeida
Universidade de Coimbra (UC)

PTDC/SAU-TOX/117704/2010

Evaluation of Neurotoxicity Biomarkers for the Anti-HIV Drug Efavirenz.
Alexandra Maria Moita Antunes
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-TOX/117723/2010

OSTEOSCREEN - Screening for molecules with osteogenic activity in zebrafish
Leonor Cancela
Centro de Ciências do Mar (CCMar)

PTDC/SAU-TOX/117767/2010

Is methamphetamine self-administration associated with the activation of the brain receptor for advanced glycation end product (RAGE)?
Frederico Guilherme de Sousa da Costa Pereira
Universidade de Coimbra (UC)

PTDC/SAU-TOX/117811/2010

Artemisinins as potential anticancer drugs for breast cancer therapy
Isa da Conceição Lopes Cavaco
Universidade do Algarve (UAlg)

PTDC/SAU-TOX/117905/2010

Adenosinergic system in vascular responsiveness and hypertension: mechanistic interactions between ROS generation and NO levels
Carmen Diniz Pereira
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/117931/2010

TAKING GENETIC TOXICOLOGY INTO A NEW DIMENSION: IMPLEMENTATION AND VALIDATION OF THE HUMAN MAMMARY 3D CELL MICRONUCLEUS ASSAY
Nuno Filipe da Rocha Guerreiro de Oliveira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/117942/2010

Pharmacogenomics and inidividualization of isoniazid therapy
Henriqueta Alexandra Mendes Brêda Lobo Coimbra Silva
Universidade de Coimbra (UC)

PTDC/SAU-TOX/118191/2010

Toxicidade induzida por fármacos pós-transplantação renal - bases biomoleculares para a escolha de protocolos de conversão precoce ou tardia de ciclosporina A por Sirolimus e de melhor terapêutica anti-hipertensora/renoprotectora
Flávio Nelson Fernandes Reis
Universidade de Coimbra (UC)

PTDC/SAU-TOX/118269/2010

Surfactants in the Prophylaxis of Sexually Transmitted Infections and in Oral Hygiene
Otília Vieira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/118296/2010

Alterations of the synaptic proteome in the pilocarpine model of temporal lobe epilepsy: effect of different antiepileptic treatments
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/118931/2010

Effect of Erythropoietin on the Multiple Organ Dysfunction Associated to Burn Injury
Hélder Dias Mota Filipe
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/119379/2010

Nuclear receptors as xeno-sensors in antimalarial and anti-TB combination therapy
Jose Pedro Blanco Panadés Gil
Universidade do Algarve (UAlg)

PTDC/SAU-TOX/119476/2010

Development of physiologically based pharmacokinetic models to support drug discovery.
Paulo Jorge Pereira Alves Paixão
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/119517/2010

Synthesis, characterization, biokinetics and toxicity of gold nanoparticles
Maria de Lourdes Bastos
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/119525/2010

Regulation of erythropoietin gene expression in non-renal tissues
Elisio Manuel Sousa Costa
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-TOX/119599/2010

Alpha2C adrenoceptors as potential therapeutic target in Parkinson´s disease
Jose Eduardo Ferreira Moura
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-TOX/119759/2010

NAPHTOX: Evaluation of the citotoxicity levels induced by naphthoquinones with anticancer and antimicrobial potential
Paula Cristina Branquinho de Andrade
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/119845/2010

Anti-parasitic activity of natural products from Brazilian Nordeste marine algae and Amazonian plants
MARIA DE FÁTIMA CARVALHO NOGUEIRA
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-TOX/120000/2010

Perinatal maturation of vascular responses mediated by G-protein-coupled receptors
Daniel Filipe de Lima Moura
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-TOX/120001/2010

ALSilence - Effects of mutant SOD1 gene silencing and immunodulation with anti-CD40L on the neuromuscular system in Amyotrophic Lateral Sclerosis (ALS)
Paula Alexandra Costa Marçal Correia
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-TOX/120261/2010

Acting on Apoptosis Targets to Improve Neural Differentiation: A Novel Role for Ursodeoxycholic Acid
SUSANA ZEFERINO SOLÁ DA CRUZ
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/120281/2010

Intrarenal angiotensinogen and oxidative stress: new targets to improve Heart Failure management?
António Albino-Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-TOX/120351/2010

CANCANOMICS: EchinoCANdin drug resistance in CANdida glabrata: a PharmacogenOMICS approach
Miguel Cacho Teixeira
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-TOX/120541/2010

S-glutathionylation in the PERK-Nrf2 pathway: So many stresses, so little time.
Maria João Carlos da Silva Gama
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/120592/2010

Cytotoxicity mechanisms of retinoids derivatives in combination with antiestrogens 4-hydroxytamoxifen and endoxifen
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/120829/2010

Exploring the Combined Use of Epigenetic and Conventional Therapy in Prostate Cancer Treatment
Carmen Jerónimo
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-TOX/121069/2010

BREAST CANCER CHEMOTHERAPEUTIC AGENTS: THE IMPACT OF BASE EXISION REPAIR DNA POLYMORPHISMS IN DRUG RESPONSE
Jorge Francisco Dias Rodrigues Gaspar
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-TOX/121205/2010

Candida and catecholamines: elucidation of its impact upon antifungal resistance, morphogenesis and cell cycle
Cidalia Pina Vaz
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-TOX/121317/2010

Meconium: an important source of information in the assessment of fetal drug exposure.
Eugenia Gallardo
Universidade da Beira Interior (UBI)

PTDC/SAU-TOX/121469/2010

EnDis-Sensor - Endocrine disruptors: infant food study, evaluation and chemical sensor development.
Elvira Maria Mendes Sardão Monteiro Gaspar
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-TOX/121722/2010

Efflux pumps: their role in resistance phenotypes to disinfectant agents in Toxocara canis and in the mode of action of new natural compounds of plant origin
Ana Júlia Pinto Fonseca Sieuve Afonso
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-TOX/121731/2010

p63 and its targets in neurogenesis: modulation by tauroursodeoxycholic acid
Filipa Nunes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/121814/2010

Myristicin: a potential chemopreventive agent
António Sebastião Rodrigues
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-TOX/121949/2010

Modulation by adenosine receptors of the protective and deleterious roles of astrocytes
PAULA MARIA GARCIA AGOSTINHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/121988/2010

Inhibitors of Cytidine Deaminase for the treatment of B-cell lymphoma, lymphocytic leukemia, other tumors and autoimmune disease.
Vasco M Barreto
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-TOX/122161/2010

Molecular and cellular studies on the role of PGRMC1 in breast cancer chemotherapy resistance.
Michel Kranendonk
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-TOX/122188/2010

Pharmacogenomics in stroke: identifying genetic factors for stroke recovery and clinical outcome after therapy with recombinant tissue Plasminogen Activator (tPA)
Astrid Vicente
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-TOX/122248/2010

Pathophysiologic relevance of the activation of trophic factor receptors upon the adenosine A2A receptor blockade-mediated neuroprotection in degenerative conditions
Catarina Alexandra Reis Vale Gomes
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/122355/2010

SARTANS - Selective AT1 Receptor Antagonists as PPAR-modulators. New TArgets in cardiovascular disease and metabolic Syndrome.
Helder Jose Marques Pinheiro
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/122526/2010

Predictive risk assessement of occupational exposure to mixtures of neurotoxic metals
Ana Paula Marreilha dos Santos
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-TOX/122553/2010

Activation of the innate pro-inflammatory response by magnetic nanoparticles
Eduarda das Graças Rodrigues Fernandes
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-TOX/122736/2010

Estradiol and testosterone in chondrogenic differentiation and phenotypic stabilization of human adipose stem cells: new targets and modulators for cartilage repair
Alexandrina Maria Ferreira dos Santos Pinto Mendes
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/122822/2010

New insights on the role of adenosine signaling pathway in pulmonary hypertension
Ana Patrícia Fontes de Sousa
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-TOX/122894/2010

Therapeutic potential of caffeine and adenosine A2A receptor antagonists in ADHD (Attention Deficit and Hyperactivity Disorder)
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/122906/2010

Role of chromatin and protein modification with SUMO and Ubiquitin in the efficacy of topoisomerase2-specific drugs
João António Augusto Ferreira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-TOX/122928/2010

Mushroom intoxications: Development of antidotes for amatoxins
Félix Carvalho
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/116590/2010

Plasmepsin V as new target for malaria chemotherapy - Inhibition studies and structural characterization
Pedro Miguel Dias Castanheira
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/SAU-FAR/116741/2010

Inhibiting the CXCL12/CXCR4/CXCR7 chemokine axis in cancer by rational structure-based drug design
Marco André Coelho das Neves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/116816/2010

Pathophysiological and therapeutic role of urocortin-2 system in pulmonary hypertension
Carmen Dulce da Silveira Brás Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FAR/116941/2010

Identification of novel putative drugs and drug targets for the treatment of Huntington´s disease
Federico Herrera
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-FAR/116972/2010

NanoLBG: Locust bean gum-based nanocarriers for oral delivery of biopharmaceuticals
Ana Margarida Moutinho Grenha
Universidade do Algarve (UAlg)

PTDC/SAU-FAR/117062/2010

Can nanoparticles increase value of insulin oral delivery
António José Ribeiro
Universidade de Coimbra (UC)

PTDC/SAU-FAR/117469/2010

Cancer Multidrug Resistance and Cancer stem cells - functional identification
Filipa Fernandes Mendes
Instituto Tecnológico e Nuclear (ITN)

PTDC/SAU-FAR/117619/2010

Controlling infections due to Trypanosomatids by targeting specific small molecules
Joana Alexandra Pinto da Costa Tavares
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FAR/118082/2010

Nanoparticulate calcium phosphate bone cements as antibiotic delivery systems for osteomyelitis treatment.
António José Leitão das Neves Almeida
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/118268/2010

Functional analysis of AQPs in the adipose cell and search for activity regulators
Maria da GRAÇA Tavares Rebelo de SOVERAL Rodrigues
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-FAR/118459/2010

Towards malaria eradication. A novel approach for multi-targeting the parasite´s life cycle
Francisca Lopes
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/118461/2010

Glutamate antagonists and aromatase inhibitor in combination with active tamoxifen metabolites: Promising new therapeutic strategies for breast cancer?
José Barata Antunes Custódio
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/118475/2010

Molecular and functional characterization of pro-apoptotic extrolites from Penicillium chrysogenum strains
Francisco Javier Enguita
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-FAR/118649/2010

BYNOSE - Development of hybrid nanostructured systems using precipitation clean technologies for nose-to-brain drug delivery: overcoming CNS-barriers.
Ana Alexandra Figueiredo Matias
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-FAR/118787/2010

ARE MICROGLIA A NEW POTENTIAL PHARMACOLOGICAL TARGET IN AMYOTROPHIC LATERAL SCLEROSIS (ALS)?
Dora Brites
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/118976/2010

Acetyl-L-carnitine action in extracellular signaling
Maria Teresa Burnay Summavielle
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FAR/119029/2010

SECOLIVE. Secoiridoids in olive seeds: isolation, characterization and potential uses
Maria do Rosário Beja de Figueiredo Gonzaga Bronze
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-FAR/119127/2010

Influence of fluid therapy on Local and Systemic Inflammation, and on Drug Therapy. Role of New Drug Delivery Systems and Nanomedicine
Maria Luísa Teixeira de Azevedo Rodrigues Corvo
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/119173/2010

ArmAb: New strategy of ADC for arming antibodies in cancer therapy
Joao Goncalves
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-FAR/119389/2010

TherMelVac- dendritic cell-targeted peptide vaccine against melanoma by ligand-modified nanoparticles
Helena Isabel Fialho Florindo Roque Ferreira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/119588/2010

Development of a new drug carrier with potential neuroprotective effect in the Parkinson´s disease
Ana Figueiras
Universidade da Beira Interior (UBI)

PTDC/SAU-FAR/119647/2010

New therapeutic approaches for the treatment of ischaemic retinopathies
BERTA MARIA FERNANDES FERREIRA SÃO BRAZ
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-FAR/119712/2010

Research on pharmaceutical co-crystals of nonsteroidal anti-inflammatory drugs: a new approach to oral bioavailability enhancement and to the synthesis of combination drugs
João Carlos Canotilho Lage
Universidade de Coimbra (UC)

PTDC/SAU-FAR/119720/2010

Towards a targeted synergistic drug cocktail for the treatment of chemoresistant human breast cancer
João Nuno Sereno de Almeida Moreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/119727/2010

Peroxide-based hybrid drugs directed to plasmodial DNA as a strategy to overcome selection of resistance to antimalarial drugs
Maria de Lurdes dos Santos Cristiano
Centro de Ciências do Mar (CCMar)

PTDC/SAU-FAR/119852/2010

Antigen delivery through the first line of defense: a strategy for transcutaneous immunization against Helicobacter pylori
Sandra Simões
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/120175/2010

Natural agents to combat Alzheimer`s disease: development of an integrated methodology for efficient screening of active compounds
Patrícia Carla de Jesus Duarte Macedo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-FAR/120357/2010

NanoProtectBrain - Exploiting Hypericum perforatum antioxidant and neuroprotective properties through targeted brain extracts and compounds delivery via nanoparticles
Bruno Sarmento
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-FAR/120380/2010

Comparing the Membrane Permeability and Uptake Transporter-Enzyme Interplay of CYP3A Substrate Drugs between the Intestine and Liver
José Augusto Guimarães Morais
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/120398/2010

CARING-FILM - Combination AntiRetrovIral-loaded Nanoparticles-in-vaGinal FILM systems for preventing HIV transmission
Bruno Sarmento
Cooperativa de Ensino Superior Politécnico e Universitário, CRL (CESPU)

PTDC/SAU-FAR/120453/2010

siRNA incorporation in a lipid/micelle-based nanocarrier as a strategy to restore E-cadherin expression and eradicate advanced breast cancer metastatic phenotype
Mafalda de Castro Ascensão Marques Videira
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/120472/2010

Venomics of European Vipera family - inspiration for design of new peptidomimetic antithrombotic drugs
Deborah Penque
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-FAR/120515/2010

Interaction of Leishmania with monocyte-derived macrophage and dendritic cells: application to Leishmania/HIV coinfection treatment
Maria do Céu Rodrigues de Sousa
Universidade de Coimbra (UC)

PTDC/SAU-FAR/120517/2010

Agentes Modificadores da Doença para uma Terapêutica Inovadora da Doença de Alzheimer
Sérgio Manuel Marques
Instituto Superior Técnico (IST/ULisboa)

PTDC/SAU-FAR/120677/2010

Nanostructured biomimetic interfaces for enzyme studies applications
Maria de La Salette de Freitas Fernandes Hipólito Reis
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/120747/2010

Lung renin-angiotensin system: the role of AT-2 receptor on pathophysiology of pulmonary arterial hypertension
Tiago Alexandre Henriques Coelho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-FAR/120861/2010

LIFIMB - Lead Identification of Falcipain Inhibitors from Malaria Boxes
Cátia Teixeira
Universidade de Aveiro (UA)

PTDC/SAU-FAR/121674/2010

Development of a poly(glutamic acid)-paclitaxel conjugate with potential for clinical translation
Rogério Paulo Pinto de Sá Gaspar
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/121808/2010

Exploring mycobacteriophage lysis properties to target the mycobacteria cell envelope
Madalena Maria Vilela Pimentel
Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia (ADEIM)

PTDC/SAU-FAR/121911/2010

Development of high-throughput screening strategies for in vitro drug profiling with applications in drug discovery research
MARLENE SUSANA DIONISIO LÚCIO
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/121937/2010

MedMilk - Medicinal milks to deliver drugs in paediatrics
João Fernandes de Abreu Pinto
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/121944/2010

A new approach to the design of drug-like DNA G-quadruplex ligands, a novel class of selective anticancer agents
Maria Alexandra da Silva Paulo
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/122017/2010

Modern NMR techniques in drug discovery: Design of new matrix metalloproteinases inhibitors for cancer therapy
Raquel Grazina
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-FAR/122022/2010

Novel analytical approaches to assess the antioxidant activity of drugs using oxidative biological targets: the pleiotropic effects of statins
Luis Miguel Andrade de Magalhães
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-FAR/122058/2010

Identification and pharmacological characterization of small molecules from plant origin for development of new drugs for chronic inflammation.
Carlos Manuel Freire Cavaleiro
Universidade de Coimbra (UC)

PTDC/SAU-FAR/122074/2010

Histone deacetylase inhibition and estrogen receptor alpha antagonism by hybrid molecules. Rational design, synthesis and evaluation of anticancer compounds with dual activity.
Maria Manuel Cruz Silva
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/122668/2010

Nano/micro particles delivery systems on the development of heterologous prime-boost vaccines
Lídia Maria Diogo Gonçalves
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/122757/2010

Inclusion of natural compounds on cyclodextrins: Evaluation of eficacy and development of a new drug delivery system for the treatment of recurrent vulvovaginal candidosis
José António Martinez Souto de Oliveira
Universidade da Beira Interior (UBI)

PTDC/SAU-FAR/122940/2010

Design and characterization of enzymatic (de)glycosilation systems towards neuroprotective drugs
Maria Henriques Lourenço Ribeiro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-FAR/123092/2010

Supercritical fluid-assisted preparation of demulcent/protein/drug delivery contact lenses to improve the dry eye syndrome treatment
Mara Elga Medeiros Braga
PRODEQ - Associação para o Desenvolvimento da Engenharia Química (PRODEQ)

PTDC/SAU-ONC/116655/2010

The role of KRAS mutations signalling in autophagy regulation in colorectal carcinoma: towards identification of new molecular targets.
Ana Preto
Universidade do Minho (UM)

PTDC/SAU-ONC/116821/2010

Establishing anti-telomerase terapeuthics for invasive melanoma in zebrafish
Miguel Godinho Ferreira
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ONC/117088/2010

Implications of Claspin mutations in the maintenance of cell homeostasis, oncogenesis and response to chemotherapy
Teresa Maria Caldeira Martins
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ONC/117348/2010

EPID 3D in vivo dosimetry
Brígida Costa Ferreira
Universidade de Aveiro (UA)

PTDC/SAU-ONC/117401/2010

Dissecting the molecular pathways underlying crosstalk between the thymic microenvironment and T-cell acute lymphoblastic leukemia
Matthias Erwin Futschik
Universidade do Algarve (UAlg)

PTDC/SAU-ONC/117673/2010

Identification of novel ETS fusion genes and their downstream targets in sporadic and familial/hereditary prostate cancer
Manuel António Rodrigues Teixeira
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ONC/117745/2010

SCAFFOLDS4CANCER - Establishment of a 3D angiogenic model for the study of uterine cervix tumours.
Ana Rita da Costa Pinto
Universidade do Minho (UM)

PTDC/SAU-ONC/117855/2010

New therapeutic targets for primary liver tumors
José Guilherme Lopes Rodrigues Tralhão
Universidade de Coimbra (UC)

PTDC/SAU-ONC/117961/2010

Development of novel therapies and biomarkers for human gliomas
Jorge Filipe de Almeida Vieira Lima
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/118058/2010

Amniotic membrane: a therapeutic option against cancer?
Maria Filomena Rabaça Roque Botelho
Universidade de Coimbra (UC)

PTDC/SAU-ONC/118213/2010

Light and Radiotherapy for oesophageal cancer
Maria Filomena Rabaça Roque Botelho
Universidade de Coimbra (UC)

PTDC/SAU-ONC/118287/2010

Genomics and Proteomics to identify biomarkers of drug resistance and progression in chronic myeloid leukemia
António Sebastião Rodrigues
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/118587/2010

Combination therapeutic schemes for breast cancer metastatic bone disease
Sandra Cristina Cara de Anjo Casimiro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ONC/118993/2010

Development of an innovative cell based phenomics high-throughput screening platform for individual oncology patient anti-TRK agents sensitivity assessment.
Alain José da Silva Morais
Universidade do Minho (UM)

PTDC/SAU-ONC/119275/2010

Role of Cancer Stem Cells in Tumorigenesis and Chemoresistance in Osteossarcoma by in vivo Molecular Imaging with PET
Célia Maria Freitas Gomes
Universidade de Coimbra (UC)

PTDC/SAU-ONC/119445/2010

Melanoma ER stress induced by chemotherapy. Role of Protein Disulfide Isomerase family members
Carlos Manuel Mendes Novo
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ONC/119473/2010

The effects of intense pulsed light on normal skin and in a two-stage skin cancer model
Paula Alexandra Martins de Oliveira
Universidade de Trás-os-Montes e Alto Douro (UTAD)

PTDC/SAU-ONC/119731/2010

Microenvironment in oral squamous cancer cells : interference with PI3K/AKT/mTOR pathway
Henriqueta Alexandra Mendes Brêda Lobo Coimbra Silva
Universidade de Coimbra (UC)

PTDC/SAU-ONC/119893/2010

(Sia)Signature And Enhancement Of Intravesical Bladder Cancer Therapy
Paula Alexandra Quintela Videira
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/119965/2010

Effect of the histone deacetylase inhibitor Vorinostat in hematopoietic cell differentiation: molecular mechanisms and clinical implications for myelodysplasia
Gabriela Medeiros Silva
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/120016/2010

Laminin-332 in cervical carcinoma - a prognostic factor and a new therapeutic target
Ana Maria Felix de Campos Pinto
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/120066/2010

How do Prodigionines, the novel anticancer drugs, target and regulate PP1/AKT complex?
Margarida Fardilha
Universidade de Aveiro (UA)

PTDC/SAU-ONC/120587/2010

Indução de lesões no ADN como meio de reduzir a toxicidade de tratamentos quimio-radioterápicos.
Maria de Fátima Guerreiro da Silva Campos Raposo
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FCTUNL/UNL)

PTDC/SAU-ONC/121169/2010

LiSSSA - Light Scattering Spectroscopy for Non-invasive Early Diagnosis of Stomach Adenocarcinoma
Joaquim Agostinho Moreira
Faculdade de Ciências da Universidade do Porto (FCUP/UP)

PTDC/SAU-ONC/121349/2010

Understanding Sensitivity and Resistance to Targeted Therapies in Hematological Neoplasias
Ana Bela Sarmento Ribeiro
Universidade de Coimbra (UC)

PTDC/SAU-ONC/121464/2010

SCL-BioM - Screening Lung Cancer: Biomarkers
Elvira Maria Mendes Sardão Monteiro Gaspar
Fundação da Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (FFCT/FCT/UNL)

PTDC/SAU-ONC/121573/2010

Canonical and noncanonical NF-kappaB signaling in acute T-cell leukemia
Nuno Alexandre Pinto Rodrigues dos Santos
Universidade do Algarve (UAlg)

PTDC/SAU-ONC/121670/2010

Development of function blocking antibodies using Phage Display Technology: Inhibiton of the Notch1 signaling pathway by function blocking anti-jagged 1 antibody.
Ana Barbas
Instituto de Biologia Experimental e Tecnológica (IBET)

PTDC/SAU-ONC/121742/2010

Investigation on the effect of Dll4Fc anti-angiogenic tumour therapy on metastatic dissemination
Alexandre José Neto Trindade
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-ONC/121933/2010

Biology of pancreatic cancer stem cells - the relevance of MUC1 protein
Luis Filipe Santos Silva
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/122023/2010

Identification of microRNAs that modulate the communication between bone marrow endothelial cells and hematopoietic stem cells: implications in normalcy and in disease
Ana Margarida Silva Bexiga Costa
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ONC/122051/2010

Epigenetic signature of prostate cancer stem cells
Carmen Jerónimo
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ONC/122428/2010

Dissecting the impact of IL7R gain-of-function mutations in T-cell leukemia
João Pedro Taborda Barata
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ONC/122587/2010

Specific targeting to proteasomal degradation of the human neurotropic polyomavirus JC large T antigen: effect on controlling its oncogenic transformation potential in transfected human colorectal epithelium cells
Luis Almeida
Universidade de Coimbra (UC)

PTDC/SAU-BID/116779/2010

The role of Viriato and nucleolar-based events in the cellular responses to Myc activity.
Paulo Jorge Sousa Nunes Pereira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BID/117120/2010

Role of embryonic tissue-resident macrophages in lung development
SANDRA MARIA ARAÚJO DA COSTA
Universidade do Minho (UM)

PTDC/SAU-BID/117158/2010

Identifying the function of different cilia types in early left right development
Susana Santos Lopes
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-BID/117418/2010

Identification and Functional Characterization of Prrxl1 Target Genes in Nociceptive System Development
Deolinda Maria Valente Alves Lima Teixeira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-BID/118072/2010

PRO-MATURUS. Linear and nonlinear analysis of uterine contractions recordings in promotion of fetal maturity. Application to screening and diagnosis of preterm labor and dystocia.
Hernâni Manuel da Silva Lobo Maia Gonçalves
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-BID/118267/2010

CardiON - The Ontogeny of Cardiac-(Re)genesis
Perpetua Pinto do Ó
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BID/118584/2010

Interplay between biological clocks operating in life
Isabel Maria Mestre Marques Palmeirim
Universidade do Algarve (UAlg)

PTDC/SAU-BID/119194/2010

Schizophrenia is a neurodevelopmental disorder: do genes and environment meet to regulate cerebrospinal fluid dynamics?
Joana de Almeida Santos Pacheco Palha
Universidade do Minho (UM)

PTDC/SAU-BID/119295/2010

TBCCD1: A Novel centrosomal protein involved in centrosome-nucleus connection
Maria Helena Antunes Soares
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-BID/119627/2010

Uncover the molecular mechanism downstream of Dmrt2a/Terra that coordinates symmetry versus asymmetry along the left-right axis
Maria Leonor Tavares Saúde
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BID/119995/2010

Role of adrenaline on the maturation of the different beta-adrenoceptor subtypes
Mónica Isa Moreira Rodrigues
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BID/120079/2010

The physiology of body size: how nutrition controls ecdysone synthesis to regulate developmental processes in Drosophila melanogaster
Christen Mirth
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BID/120115/2010

The role of checkpoint genes during development and tumourigenesis in Drosophila melanogaster
Sara Luisa Morais da Silva
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BID/120130/2010

The laminin matrices of early skeletal muscle development: a changing tissue microenvironment regulating myogenic differentiation and morphogenesis.
Solveig Thorsteinsdottir
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-BID/120138/2010

PRO-FERTILTREAT - Prediction of Reproductive Outcome during Fertility Treatments
Maria Irene de Oliveira Monteiro Jesus Rebelo
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-BID/120488/2010

MicroRNAs regulating vertebrate bone development and mineralization (BonemiR)
Daniel António Martins Tiago
Centro de Ciências do Mar (CCMar)

PTDC/SAU-BID/120511/2010

Computer alerts for reducing intrapartum fetal asphyxia
Diogo de Matos Graca Ayres de Campos
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BID/120783/2010

Understand the role of F-actin in proliferation and apoptosis mediated by the Src proto-oncogene
Florence Janody
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BID/121630/2010

Molecular parallelisms in vertebrate segmentation and lung development
Rute S Moura
Universidade do Minho (UM)

PTDC/SAU-BID/121735/2010

Exploring nuclear roles of small regulatory RNAs in somatic cell reprogramming
Maria Joana Pinto Desterro
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BID/121846/2010

The V2 domain of the spinal cord as a model to study neuronal fate decisions
Domingos Manuel Pinto Henrique
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-BID/121935/2010

Function of the zinc-finger factor Myt1 in vertebrate neurogenesis: a combined approach of mouse genetics and genomics
Diogo Pinto da Cruz Sampaio e Castro
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-BID/122835/2010

Regulatory and functional evolution upon gene duplication
José Élio da Silva Sucena
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ORG/116826/2010

Telomerase-dependent rejuvenation in Zebrafish
Miguel Godinho Ferreira
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ORG/116898/2010

Gastrointestinal mural transmural endoscopic procedures
Carla Rolanda da Rocha Gonçalves
Universidade do Minho (UM)

PTDC/SAU-ORG/116978/2010

Elucidating the Crucial Role of GRK4 Variants and GADD34 in Renal Dopamine D3 Receptor Expression and Function and in the Pathogenesis of Hypertension
Maria João Jorge Pinho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/117017/2010

Intestinal metaplasia of the stomach: study of a regenerative carcinogenic process centered on BMP-mediated CDX2 regulation
Raquel Maria da Silva Graça Almeida
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ORG/117054/2010

Diabetic nephropathy as an inflammatory disease: search for new molecular targets with therapeutic relevance based on the characterization of adenosine-mediated effects
Manuela Morato
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ORG/117064/2010

Protein interaction mechanisms in transcriptional regulation: modulation of ataxin-2 as therapeutic target for Machado-Joseph Disease.
Clevio David Rodrigues Nobrega
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/117110/2010

Role of reduced renal dopaminergic activity and vitamin D3 deficiency on natriuretic peptide system dysfunction in nephrotic syndrome
Manuel Pestana
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/117127/2010

Cancer stem cells in liver hepatocellular carcinoma
LUÍS FILIPE FORTADO SOARES TOMÉ
Universidade de Coimbra (UC)

PTDC/SAU-ORG/117170/2010

Brain Derived Neurotrophic Factor (BDNF) in the diagnosis and phatophysiology of the overactive bladder syndrome.
Célia da Conceição Duarte Cruz
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/117220/2010

The role of lipocalin 2 in the crosstalk between the immune and the central nervous systems
Fernanda Cristina Gomes de Sousa Marques
Universidade do Minho (UM)

PTDC/SAU-ORG/117266/2010

Insights into Gla-rich Protein (GRP) function and molecular mechanism of action in vascular calcification (BioGlaGRP)
Carla Alexandra São Bento Viegas
Centro de Ciências do Mar (CCMar)

PTDC/SAU-ORG/117438/2010

Role of obesity and pressure-overload in the genesis of diastolic heart failure
Joaquim Adelino Correia Ferreira Leite Moreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/117594/2010

The role of autoantibodies and B1 cells in the early steps of type 1 diabetes
Nádia Cristina Varela da Silva Duarte
Fundação Calouste Gulbenkian (FCG)

PTDC/SAU-ORG/117680/2010

Non-invasive Magnetic Resonance Biomarkers for the diagnosis and follow-up of Non-alcoholic Steatohepatitis
Carlos Geraldes
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/117700/2010

Prevention of I/R injury associated with cold preservation: modulation of cyclophilin D activity and induction of mitochondrial permeability transition
Anabela Pinto Rolo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/117884/2010

RNA toxicity in oculo-pharyngeal muscular dystrophy as a new paradigm for targeted therapeutics in muscular dystrophies
Francisco Javier Enguita
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/117891/2010

Is bladder pain syndrome/interstitial cystitis a sympathetic dysautonomia? Experimental and clinical implications
Francisco José Miranda Rodrigues Cruz
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/118013/2010

The effect of positive pressure ventilation and the differential effect of distinguishing values of positive end expiratory pressure in systemic inflammation and visceral organs. Evaluation on an animal model.
Paulo Alexandre do Rosário Marcelino
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ORG/118096/2010

Biphosphonates and jaw iatrogenic osteonecrosis
Manuel Marques Ferreira
Universidade de Coimbra (UC)

PTDC/SAU-ORG/118197/2010

Molecular pathways and proteomics in diabetic skin wound healing
EUGÉNIA MARIA LOURENÇO DE CARVALHO
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/118200/2010

Cardiovascular assessment in a population of monochorionic twins
Edite Serrano Gonçalves
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/118207/2010

Splicing mutations: making sense with antisense therapy
Isabel Maria Antolin Martins-de-Carvalho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/118209/2010

A rescue screen of combinations of chemical compounds in zebrafish models for polycistic kidney disease
Susana Santos Lopes
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ORG/118235/2010

Effects of intradialytic resistance training on muscle strength, bone mineral density and functional capacity in hemodialysis patients
André Novo
Instituto Politécnico de Bragança (IPBragança)

PTDC/SAU-ORG/118273/2010

Role of Wnt signalling in heart disease
Sonia Alexandra Vieira e Pinho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/118357/2010

Oxidative stress in pulmonary hypertension: the role of oxidized plasma proteins in vascular dysfunction
Tiago Alexandre Henriques Coelho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/118541/2010

The future of fatty livers in surgery and transplantation: is preconditioning and mitochondrial tolerance a useful strategy to overcome ischemia/reperfusion injury?
Carlos Palmeira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/118723/2010

Exploiting the interplay between cellular redox balance and breast cancer invasiveness
Matilde da Luz dos Santos Duque da Fonseca e Castro
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/118861/2010

Identification of new proteins involved in colorectal cancer due to internal ribosome entry site (IRES)-mediated translation
Luísa Romão
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ORG/118977/2010

Cholesterol as a pathogenic agent and a potential therapeutic target for CLN6 neurodegenerative disease
CARLA ANDREIA FIDALGO TEIXEIRA
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/119128/2010

Inflammation, iron and lipid homeostasis: a new perspective to study the role of immune cells in atherogenesis
LUCIANA MARIA GONÇALVES DA COSTA
Pró-INSA, Associação para a Promoção da Investigação em Saúde (Pró-INSA/INSARJ)

PTDC/SAU-ORG/119150/2010

Unraveling the role of microRNA in left ventricular reverse remodeling and its potential therapeutic implications
Inês Falcão Pires
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/119171/2010

Regulatory T cells as a target in the treatment of autoimmune diseases
Iris Caramalho
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/119236/2010

IRON AND LYMPHOCYTE HOMEOSTASIS: implications for the pathogenesis of Hemochromatosis
Maria da Graça Beça Gonçalves Porto
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/119297/2010

Controlling neuroinflammation in the retina through A2AR modulation: potential therapeutic implication in glaucoma
Ana Raquel Sarabando Santiago
Universidade de Coimbra (UC)

PTDC/SAU-ORG/119474/2010

Neuropeptide Y system: a new major player and therapeutic target in diabetic retinopathy?
António Francisco Rosa Gomes Ambrósio
Universidade de Coimbra (UC)

PTDC/SAU-ORG/119603/2010

O papel da Autofagia na patogénese das Doenças Lisossomais de Sobrecarga
Sandra Catarina da Conceição Alves
Instituto Nacional de Saúde Dr. Ricardo Jorge (INSARJ)

PTDC/SAU-ORG/119742/2010

Novel Molecular Mechanisms of Epithelial Cell Differentiation and Inflammation in Cystic Fibrosis Lung
Teresa Maria Dos Santos Pereira
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ORG/119782/2010

A novel signalling pathway possibly involved in renal salt handling and hypertension
Peter Jordan
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ORG/119796/2010

Unraveling microRNA regulators of adult cardiac stem cells
Margarida Henriques da Gama Carvalho
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-ORG/119818/2010

Bilirubin-Induced Neurological Damage: Exploring Developmental Windows of Susceptibility and Enduring Cognitive or Behavioural Deficits
Dora Brites
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/119842/2010

NecroPT - Targeting Hepatocyte Necroptosis to Treat Liver Diseases
Joana São José Dias Amaral
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/119854/2010

Study of the neuroprotective role of adenosine in diabetic retinopathy
Paulo Fernando Martins dos Santos
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/119916/2010

IRONBONE_Identification of molecular players in iron-related osteoarthritis: Hereditary Hemochromatosis as a case study
Leonor Cancela
Centro de Ciências do Mar (CCMar)

PTDC/SAU-ORG/120007/2010

Comparative study of tight junctions in wound healing
António Alfredo Coelho Jacinto
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/120025/2010

Role of Arl13b in cardiac development
Duarte Barral
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ORG/120117/2010

Relevance of HGF/c-Met signalling pathway in lung hypoplasia development
SANDRA MARIA ARAÚJO DA COSTA
Universidade do Minho (UM)

PTDC/SAU-ORG/120142/2010

Pathophysiological mechanisms in rotavirus diarrhea: emphasis on intestinal motility, prostaglandins, and aspirin
Claudia Istrate
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-ORG/120145/2010

How to build a model for sacral nerve stimulation? An interdisciplinary research program in Humans
Maria Amélia Duarte Ferreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/120150/2010

Dissecting the molecular mechanisms of EPC response to myocardial ischemia in diabetes: from bench to bedside
Rosa Cristina S Fernandes
Universidade de Coimbra (UC)

PTDC/SAU-ORG/120198/2010

Physiological and Clinical Importance of the Parasympathetic Nervous System in Glucose Homeostasis
Andrea Natali
Faculdade de Ciências Médicas (FCM/UNL)

PTDC/SAU-ORG/120220/2010

A new strategy for therapeutic angiogenesis: Low doses of Ionizing radiation
Susana Constantino Rosa Santos
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/120243/2010

Metabolic profile in pre-clinical stages of Alzheimer`s disease: looking for the metabolic link
Rui de Albuquerque Carvalho
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/120335/2010

Stduy of molecular mechanisms leading to medullary cystic kidney disease - first approach in Portugal
Gabriel Miltenberger-Miltenyi
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/120374/2010

Redox balance alterations in aged female reproduction: role in placental disorders
Elisabete Silva
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/120389/2010

DISLEEP-MSA: Autonomic progression markers of sleep disturbances on multiple system atrophy
Maria Isabel de Sousa Rocha
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/120417/2010

Longitudinal variation of peripheral refraction and its correlation with myopia onset and progression
Jorge Manuel Martins Jorge
Universidade do Minho (UM)

PTDC/SAU-ORG/120513/2010

CPEB1 - a new modulator of angiogenesis
Marta Sofia Carvalho Teixeira Pinto
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ORG/120740/2010

Molecular mechanisms involved in maintenance of pluripotency and cardiac cell lineages differentiation from embryonic
José Bragança
Universidade do Algarve (UAlg)

PTDC/SAU-ORG/120746/2010

The relationship between nutrient transport by first trimester human trophoblasts and placentation: relevance in intrauterine growth restriction
Fátima Martel
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/120777/2010

Salivary glands guanylin and natriuretic peptides systems in chronic kidney diseases
Benedita Sampaio Maia
Faculdade de Medicina Dentária da Universidade do Porto (FMD/UP)

PTDC/SAU-ORG/120802/2010

New lipids messengers in uterine tissue remodeling: implications to pregnancy outcome.
Natércia Aurora Almeida Teixeira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/120993/2010

Study of the actions of testosterone and dihydrotestosterone at the vascular level
Ignacio Verde
Universidade da Beira Interior (UBI)

PTDC/SAU-ORG/121082/2010

Crosstalk of sirtuins 1,6 and 7 in progression of age-dependent endothelium dysfunction.
Delminda Gamelas Neves Lopes de Magalhaes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/121178/2010

Identification of Autophagic Defects in Crohn`s Disease Immune Cells: Potential Target for Intervention
Fernando José Magro Dias
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/121188/2010

Cardiac rehabilitation, ventricular remodelling and underling molecular mechanisms
José Carlos de Magalhães Silva-Cardoso
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/121299/2010

Adrenergic system in immune cells: a new promising target in obesity control
Laura Virgínia Pereira Teixeira Ribeiro
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/121321/2010

Classical Galactosemia: taking a step further
Isabel Maria Antolin Martins-de-Carvalho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/121438/2010

Unexpected roles of STAT3 in thyroid carcinogenesis: an orchestrator of tumor-microenvironment crosstalk?
Ana Paula Soares Dias Ferreira
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ORG/121554/2010

O peixe Zebra como um organismo-modelo na doença de Parkinson
Ana Dulce de Ascensao Almeida Correia
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-ORG/121612/2010

ERK5-Regulated microRNA Signaling Networks in Colon Cancer and Associated Angiogenesis
Pedro Borralho
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/121643/2010

Nanotechnology applied to the treatment of hyperproliferative skin diseases
MARIA DO CÉU GONÇALVES DA COSTA
COFAC, Cooperativa de Formação e Animação Cultural, CRL (COFAC)

PTDC/SAU-ORG/121678/2010

BIG - Behind the weight gain - Proteomic analysis of saliva in obesity: effects of appetite / satiety factors
Elsa Lamy
Universidade de Évora (UE)

PTDC/SAU-ORG/121890/2010

Who comes first: The chicken or the egg? Obstructive sleep apnea syndrome or obesity? Unravelling the role of intermittent hypoxia on adipose tissue physiology
Joana Salgado
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/121954/2010

DIABETES-ASSOCIATED ERECTILE DYSFUNCTION - PURINERGIC MODULATION AND REMODELLING OF HUMAN CAVERNOSAL VESSELS
Paulo Correia de Sá
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-ORG/121963/2010

Identification of potential biomarkers in Amyotrophic Lateral Sclerosis and hypoxia using a glycomics approach
Júlia Carvalho Costa
ITQB NOVA - Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA/UNL)

PTDC/SAU-ORG/122001/2010

Identification of penile microcirculatory changes to create a compartmental model that allows a predictive and non-invasive evaluation of the vasculogenic factors of erectile dysfunction
Nuno José Duarte Monteiro Pereira
COFAC, Cooperativa de Formação e Animação Cultural, CRL (COFAC)

PTDC/SAU-ORG/122015/2010

Autonomic Nervous System and nocturnal blood pressure profiles in hypertensive patients
Jose Luis Bliebernicht Ducla Soares
Associação para Investigação e Desenvolvimento da Faculdade de Medicina (AIDFM/FM/ULisboa)

PTDC/SAU-ORG/122151/2010

Role of cancer stem cells in bladder tumor initiation and progression - self-renewal, proliferation and differentiation
Célia Maria Freitas Gomes
Universidade de Coimbra (UC)

PTDC/SAU-ORG/122178/2010

Exploring the Unexplored Phenomenon of Interallelic Complementation in Medium-chain Acyl-CoA Dehydrogenase Deficiency
Maria de Fátima Vieira Ventura
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/122192/2010

Characterization of cutaneous functional changes affecting obese patients after wheight loss
Luis António Monteiro Rodrigues
COFAC, Cooperativa de Formação e Animação Cultural, CRL (COFAC)

PTDC/SAU-ORG/122243/2010

TRAIN :: TRACE ELEMENT & HUMAN BRAIN - Age-related and region-specific changes. Changes in relation to neurodegenerative processes.
AGOSTINHO ALMIRO DE ALMEIDA
Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA)

PTDC/SAU-ORG/122250/2010

Gene expression profile of fetal cffRNA in amniotic fluid and maternal plasma in monochorionic twin pregnancies with twin-to-twin transfusion syndrome
Filipa Abreu Gomes de Carvalho
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/122279/2010

Neurodegeneration and central pathways of immuneregulation and homeostasis: impact in in-hospital morbidity and mortality
João Santos Relvas
Hospitais da Universidade de Coimbra, E.P.E (HUC/UC)

PTDC/SAU-ORG/122634/2010

Mechanisms of drug-associated hepatic steatosis: hyperacetylation of CPT1A or cellular depletion on acetyl-Coenzyme A?
Margarida Maria Fernandes Baptista e Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-ORG/122734/2010

Molecular mechanisms underlying aging-related changes in diabetic male and female rat brain: effect of insulin therapy
Ana Isabel Marques Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ORG/123059/2010

Randomized trial comparing telemedicine monitoring and titration with usual care in patients initiating Home non-invasive ventilation (TELEMOTINIV study)
João Carlos Winck
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-ORG/123084/2010

CELLAF - Cellular remodelling in paroxysmal atrial fibrillation
Mario Joao Martins Oliveira
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MET/116486/2010

Type 2 diabetes and infertility: the role of sex hormones and metabolic dysfunction in Sertoli cells
CARLOS PEDRO FONTES OLIVEIRA
Universidade da Beira Interior (UBI)

PTDC/SAU-MET/116806/2010

Endogenous Cannabinoids as Potential Biomarkers in Eating Disorders
Maria Augusta Vieira Coelho
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-MET/116933/2010

Food polyphenols and prevention of neurodegeneration.
Rui Fernando Marques da Silva
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)

PTDC/SAU-MET/117010/2010

HEARTPHENOLIVA - Contribution of olive oil polyphenolic compounds to the prevention of coronary heart disease.
Fátima Paiva-Martins
Associação para o Desenvolvimento da Faculdade de Ciências (ADFCUP/FCUP/UP)

PTDC/SAU-MET/117236/2010

New insights into the regulation of insulin-sensitive glucose transporters by protein kinases
Peter Jordan
Fundação da Faculdade de Ciências da Universidade de Lisboa, FP (FFC/FC/ULisboa)

PTDC/SAU-MET/117392/2010

Role of glycolytic metabolism in cervical cancer aggressiveness: in vitro and in vivo studies
Céline Pinheiro
Universidade do Minho (UM)

PTDC/SAU-MET/117402/2010

Modelling functional food effects on health: Impact of seafood processing technologies on nutrients bioavailability
Rogério da Silva Oliveira Mendes
Instituto Nacional de Recursos Biológicos, I.P. (INRB)

PTDC/SAU-MET/117771/2010

Structural analogues of the t10,c12-octadecadienoic acid: effects and underlying mechanisms on body fat reduction and obesity
JOSÉ ANTÓNIO MESTRE PRATES
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-MET/118090/2010

Cholesterol Homeostasis - Role of passive processes in cholesterol absorption and distribution between hydrophobic assemblies
Maria João Pedrosa Ferreira Moreno Silvestre
Universidade de Coimbra (UC)

PTDC/SAU-MET/118199/2010

Mechanisms of nutrient-sensing by the malaria parasite
Liliana Mancio-Silva
Instituto de Medicina Molecular João lobo Antunes (IMM/FM/ULisboa)

PTDC/SAU-MET/118899/2010

MetSyFOL - Does high folic acid supplementation during the periconceptional period interfere in fetal programming for Metabolic Syndrome during post-natal life?
Elisa Oliveira Braga Keating
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/119364/2010

Role of melanocortin system in human adipocyte biology
Alexandra Maria Monteiro Gouveia
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/119875/2010

On the disclosure of novel anti-adipogenic conjugated linoleic acid (CLA) compounds using distinct mammalian adipose systems
Paula Alexandra Lopes
Faculdade de Medicina Veterinária (FMV/ULisboa)

PTDC/SAU-MET/120154/2010

THE ROLE OF BONE HISTOMORPHOMETRY IN CHRONIC KIDNEY DISEASE - PREDIALYSIS AND KIDNEY TRANSPLANT
João Miguel Machado Dória Frazão
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/120458/2010

Herbal dietary supplements and antiepileptic drugs: evaluation of potentially serious drug interactions
Gilberto Lourenço Alves
Universidade da Beira Interior (UBI)

PTDC/SAU-MET/120476/2010

Antiangiogenic potential of leaves Cynara cardunculus polyphenolic rich extracts on hepatocellular carcinoma
MARIA DE FÁTIMA PEREIRA DUARTE RICARDO
Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo (CEBAL)

PTDC/SAU-MET/120554/2010

Development of an anti-ghrelin vaccine for obesity treatment
LÍDIA MARIANA RODRIGUES PEREIRA MONTEIRO
Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP)

PTDC/SAU-MET/120868/2010

Targeting the Warburg effect for cancer therapy
Valdemar de Jesus Conde Máximo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-MET/121399/2010

Molecular mechanisms of insulin resistance after immunosuppressive therapy
Daniel Omar Espinoza
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MET/121635/2010

Sweet Brains (Are Made of THL) - The weight-loss pill alli as a nootropic?
Attila Köfalvi
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MET/121672/2010

P-glycoprotein inhibition by extracts of herbs/fruits used as food: a screening program targeting multidrug resistance
Amílcar Celta Falcão Ramos Ferreira
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MET/122187/2010

Induction of AMPK activity to protect against renal injury triggered by the combination of hypertension with obesity
António Pedro Barros Gomes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-MET/122557/2010

Portuguese artisanal food yeasts: a threat for diabetic patients?
Teresa Maria Fonseca de Oliveira Gonçalves
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-MET/122944/2010

Transcriptional regulatory networks mediated by the farnesoid X receptor - physiological relevance of structural diversity
Vera Ribeiro Marques
Instituto de Higiene e Medicina Tropical (IHMT/UNL)

PTDC/SAU-MET/123029/2010

A randomized controlled trial of the efficacy and safety of different diet interventions for weight loss in subjects with asthma
André Miguel Afonso de Sousa Moreira
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-GMG/116621/2010

Global analysis of alternative polyadenylation regulators and miRNA silencing of immune modulators
Alexandra Moreira
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-GMG/120049/2010

Adhesion, Differentiation and Invasion: different processes, common cadherin players
Joana Cancela de Amorim Falcão Paredes
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-MIC/119069/2010

Mechanisms of Candida glabrata biofilms tolerance to antifungal agents
Mariana Contente Rangel Henriques
Universidade do Minho (UM)

PTDC/SAU-IMU/117057/2010

The function of the thymus in pathophysiological conditions: A systematic approach to study the expression of interleukin 7 during stress-induced thymic injury.
Nuno Miguel de Oliveira Lages Alves
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/116512/2010

Dissecting the pathogenesis of Machado-Joseph disease in a new human disease model derived from induced pluripotent stem cells
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NMC/118971/2010

The role of brain lipid metabolism in the modulation of chronic stress effects
Tiago Gil Oliveira
Universidade do Minho (UM)

PTDC/SAU-NMC/119937/2010

The “processosome”: identification and characterization of proteins promoting oligodendrocyte process outgrowth, axon wrapping and (re) myelination of axons.
Joao Carlos Bettencourt de Medeiros relvas
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NMC/120144/2010

Regulation of the ubiquitin-proteasome system by BDNF at the hippocampal synapses: role in synaptic plasticity
Carlos Jorge Alves Miranda Bandeira Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-NSC/118194/2010

The interplay between astrocytes and neurons in the progression of stress-induced pathologies
João Filipe Oliveira
Universidade do Minho (UM)

PTDC/SAU-NSC/119847/2010

Local monosynaptic connections between thalamocortical neurons in the ventrobasal complex of the rat thalamus
Peter Szucs
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-NSC/119986/2010

Damage of Primary Afferent Neurons Associated With Experimental Osteoarthritis
José Manuel Pereira Dias de Castro Lopes
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-NSC/120590/2010

Deciphering the role of Aβ and TAU among neuronal subpopulations in Alzheimer´s disease network malfunction.
Vítor Manuel da Silva Pinto
Universidade do Minho (UM)

PTDC/SAU-NSC/122254/2010

Role of accumbens and amygdala in the control of chronic stress neuropathology
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-BMA/118531/2010

Nanostructured human telomeric DNA electrochemical biosensor for screening anti-cancer drugs
Ana Maria Chiorcea Paquim
Instituto Pedro Nunes - Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia (IPN)

PTDC/SAU-BMA/118869/2010

NeurON - Molecularly-designed hydrogels for neural stem cell transplantation: a combinatorial approach for successful regeneration and functional recovery in spinal cord injury.
Isabel Freitas Amaral
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-BMA/121028/2010

Design of novel breast tumor ‘targeted` multifunctional nanoparticles
Leonardus Dorothea Kluskens
Universidade do Minho (UM)

PTDC/SAU-ENB/116850/2010

WICKEEG - A NOVEL POLYMER WICK BASED ELECTRODE FOR EEG MONITORING: FROM MATERIALS DEVELOPMENT TO IN-VIVO TESTING
José Carlos Magalhães Duque da Fonseca
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-ENB/116929/2010

BIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability
Rui Lima
Instituto Politécnico de Bragança (IPBragança)

PTDC/SAU-ENB/117631/2010

The effect of shielding on dose distributions in intra-operative electron radiotherapy: a Monte Carlo simulation study
SANDRA REBELO SARMENTO
Instituto Português de Oncologia do Porto Francisco Gentil, EPE (IPO Porto)

PTDC/SAU-ENB/118383/2010

Cognitive Rehabilitation Based on Brain-Machine Interface
Nuno Sérgio Mendes Dias
Universidade do Minho (UM)

PTDC/SAU-ENB/119132/2010

Optical Modelling of the Human Retina in Health and Disease: from structure to function.
Antonio Miguel Lino Santos Morgado
Associação para a Investigação Biomédica e Inovação em Luz e Imagem (AIBILI)

PTDC/SAU-ENB/119292/2010

Differentiation of mesenchymal stem cells to oligodendroglial lineage: complementary roles of soluble factors, extracellular matrix and mechanotransduction
MÁRIO MARTINS RODRIGUES GRÃOS
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/SAU-ENB/122128/2010

Fluorescence Lifetime Microscope for Clinical Metabolic Imaging of Corneal Tissues
Antonio Miguel Lino Santos Morgado
Universidade de Coimbra (UC)

PTDC/SAU-EPI/121532/2010

Understanding the dynamics of childhood body fat - the mediating effect of dietary patterns and eating behaviors
Andreia Cristina Matos Oliveira
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-EPI/121811/2010

Neuropsychological Assessment and Dual Genome Investigation in Frontotemporal Dementia
Manuela Grazina
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-EPI/122460/2010

Determinants of gastric and esophageal cancers incidence in the north of Portugal
Nuno Miguel de Sousa Lunet
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-SAP/116563/2010

GERIA-Geriatric study in Portugal on Health Effects of Air Quality in Elderly Care Centers
João Paulo Fernandes Teixeira
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-SAP/116738/2010

Breastfeeding and Postpartum Depression
Bárbara Fernandes de Carvalho Figueiredo
Universidade do Minho (UM)

PTDC/SAU-SAP/119192/2010

Control and Burden of Asthma and Rhinitis
João A Fonseca
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-SAP/120024/2010

Helicobacter pylori genetic variation: An opportunity to identify individuals at increased risk for disease
Ceu Figueiredo
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-SAP/121827/2010

INAIRCHILD - Indoor Air Pollution on Nurseries and Primary Schools: Impact on Childhood Asthma
Sofia Isabel Vieira de Sousa
Faculdade de Engenharia da Universidade do Porto (FE/UP)

PTDC/SAU-SAP/122904/2010

Violence in various stages of life: frequency, determinants and consequences of health
JOSÉ HENRIQUE DIAS PINTO DE BARROS
Instituto de Saúde Pública da Universidade do Porto (ISPUP/UP)

PTDC/SAU-TOX/117481/2010

The impact of exendin-4 therapy in the molecular mechanisms underlying type 2 diabetes-related long-term brain dysfunction
Ana Isabel Marques Duarte
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/117664/2010

Regulatory effects of pattern recognition receptors (PRRs) in electrolyte transport and membrane potential in intestinal epithelial cells.
Fernando José Magro Dias
Faculdade de Medicina da Universidade do Porto (FM/UP)

PTDC/SAU-TOX/117912/2010

Role of mitochondrial p66Shc in drug-induced mitochondrial toxicity memory
Ignacio Vega Naredo
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-TOX/120953/2010

Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials
Iola Melissa Fernandes Duarte
Universidade de Aveiro (UA)

PTDC/SAU-TOX/121887/2010

Personalized 3D vascular constructs for toxicity assessment- VASCTOX
MÁRIO MARTINS RODRIGUES GRÃOS
BIOCANT - Associação de Transferência de Tecnologia (BIOCANT)

PTDC/SAU-TOX/122005/2010

Physiopathological role of ecto-5`-nucleotidase - a new target for neuroprotection
Rodrigo Antunes Cunha
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/116535/2010

Non-invasive-Non-viral Silencing of Machado-Joseph disease
LUÍS FERNANDO MORGADO PEREIRA DE ALMEIDA
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-FAR/121109/2010

Neuropeptide release in wounds: a new therapeutic approach for the treatment of diabetic foot ulceration
Ermelindo Carreira Leal
Centro de Neurociências e Biologia Celular (CNBC/UC)

PTDC/SAU-ONC/117216/2010

Mucin MUC16 - CA125 cancer biomarker - biological functions and development of new biomarker assays
Maria Leonor Martins Soares David
Instituto de Patologia e Imunologia Molecular (IPATIMUP/UP)

PTDC/SAU-ONC/118346/2010

Epigenetic regulation in mammary stem/progenitor cells and its contribution to malignant transformation
Luisa Alejandra Helguero
Universidade de Aveiro (UA)

PTDC/SAU-BID/121459/2010

Regulating the pace of the Embryonic Clock: a step forward towards temporal control of cell differentiation
Raquel Gláucia Varzielas Pego de Andrade
Universidade do Minho (UM)

PTDC/SAU-ORG/116645/2010

Study of natural and synthetic inhibitors of transthyretin amyloidosis and characterization of their mechanism of action
Maria Rosário Almeida
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/118297/2010

MatriCard - Dissection and Reconstruction of the Extracellular Matrix: A Cardiac Regenerative Niche
Perpetua Pinto do Ó
Instituto Nacional de Engenharia Biomédica - INEB Univ. Porto (INEB Porto)

PTDC/SAU-ORG/118380/2010

Mecanismos de inibição neuronal na Neurofibromatose Tipo I: um modelo de translação para a compreensão de mecanismos de doença
Miguel de Sá e Sousa de Castelo Branco
Universidade de Coimbra (UC)

PTDC/SAU-ORG/118694/2010

An animal model for age-related changes in proteostasis
Henrique Girao
Universidade de Coimbra (UC)

PTDC/SAU-ORG/118863/2010

Transthyretin is a metalloprotease: possible implications in nervous system diseases
Márcia Raquel Pereira de Almeida e Liz
Instituto de Biologia Molecular e Celular (IBMC/UP)

PTDC/SAU-ORG/119296/2010

Unravelling the molecular events of gap junction remodelling in ischemic heart
Henrique Girao
Universidade de Coimbra (UC)

PTDC/SAU-ORG/120530/2010

Proteins of pancreatic zymogen granules as novel tools in molecular cell biology and medicine
Michael Schrader
Universidade de Aveiro (UA)

PTDC/SAU-MET/121133/2010

Pathways of adipose tissue dysfunction: a route for obesity- related cancer
Raquel Maria Fino Seiça
Universidade de Coimbra (UC)